Which supplements go well with Retatrutide?

Mr. Blonde said:

Silver said:

Every day I go through 2 packs of gruns. Previously I had a whole stack of other pills going. Since sticking to just the gruns, I feel an improvement.
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What exactly is meant by gruns?
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From what I understand, the pronunciation is something like grüns...
 
Psyllium husk.

Since reta reduces how quickly the stomach empties, giving digestion some help matters a lot.

Psyllium husk does a solid job of preventing stagnation. It also eases bloating.
 
cujet said:

Reta caused cramping for me. Before this, I almost never got cramps in any muscle. Now, though, it begins in my thumbs, which is really strange. For me, electrolytes are essential and they do help. I take Nutricost fruit punch electrolytes daily, and they work reasonably well. Still, getting full relief for several days means taking a lot of potassium pills.

My guess is that this comes from Reta's diuretic action.
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I appreciate you posting this. I've been getting painful cramps that come and go, and it never occurred to me they might be connected to reta. I'll give those electrolytes a shot!
 
bigbodybarry said:

Psyllium husk.

Since reta reduces how quickly the stomach empties, giving digestion some help matters a lot.

Psyllium husk does a solid job of preventing stagnation. It also eases bloating.
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Absolutely, I swear by it!...It keeps everything moving smoothly, right on schedule!....
 
For me, taking a digestive enzyme alongside each meal makes a real difference. It eases the heartburn, gas, and similar issues that come from gastric emptying slowing down.
 
Mr. Blonde said:

Silver said:

Every day I go through 2 packs of gruns. Previously I had a whole stack of other pills going. Since sticking to just the gruns, I feel an improvement.
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What exactly is meant by gruns?
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Those little gummies over at https://gruns.co/ — they cost a fair bit, but they've taken the place of quite a few capsules I was on before.
 
Shittersfull said:

The purpose of supplements is to fill the gaps in what your diet and lifestyle aren't providing. Take omega-3: if fish is a regular part of your meals, there's no need for it. Likewise, if you spend enough time in the sun, vitamin D supplementation isn't necessary.

My diet consists entirely of meat—no fruits or vegetables at all. The supplements I use are milk thistle, TUDCA, magnesium, and olive oil. I've never felt better.
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Honestly, your location plays a big role — in some places, you simply won't get enough sun exposure to reach healthy vitamin D levels. The Pacific Northwest area of North America is a prime example, especially during fall and winter: the sun's angle plus heavy, persistent cloud cover means the UVB needed for vitamin D synthesis through skin and eyes just isn't there in sufficient amounts.

Every day I use a men's 50+ multivitamin (I'm nowhere near that age, but enclomiphene makes me want added endocrine-supporting vitamins and minerals), vitamin D at 10k i.u. during fall/winter and 4k i.u. in spring/summer, omega-3, CoQ10, and OptiNAD+ (which probably isn't doing much — I'll likely swap it for actual subQ NAD+ down the road).

For sleep or stress, I keep Magnesium Citrate/Threonate, L-Theanine, and Liposomal Apigenin available and take them when needed. Now and then I'll do a pre/probiotic run for a stretch, or go through phases where I eat fermented foods regularly — that seems to really help keep gut health steady. Since I began this approach, I've never had gut problems while on first Tirz and now Reta.

I've tried dozens of supplements over the years and fallen down countless nutritional biology rabbit holes (shoutout 'examine' iykyk), yet my current stack is straightforward, works well, and is easy to stick with — no pill fatigue.

edit nearly left out Creatine, 5g twice a day. Honestly, that stuff is a life-saver.
 
ayou1316 said:

Which supplements do you combine with Reta, and which ones actually seemed to make a difference for you? Honestly, it feels like I'm stocking a whole pharmacy now.

Here's what I'm on:

omega 3s

d3-k2

Essential amino acids

NMNs

creatine together with my protein shakes

magnesium glycinate and ashwagandha taken before bed

Psyllium Husk

multi vitamin

and whenever possible, I'll have an electrolyte packet.
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I'm getting ready to begin Reta, and my stack looks a lot like yours:

Omega

NMN + TMG

Creatine

D3/K2 + Magnesium glycinate (taken before bed)

On top of that, I use Thorne's Curcumin Phytosome, Hyaluronic acid + Vit C (for my joints), Melatonin before sleep, and Shilajit to cover all the minerals I need
 
noria18 said:

I've been dealing with significant hair shedding while on reta. Are there hair supplements that work well alongside it?
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Hair loss isn’t something Reta brings on, though it can set off shedding. A few things feed into that: dropping weight, eating fewer calories, getting less protein and fewer micronutrients, plus the strain all of this puts on your system. That means using a glp by itself isn’t what makes hair fall out.
 
DC_143C said:

Shittersfull said:

The purpose of supplements is to fill the gaps in what your diet and lifestyle aren't providing. Take omega-3: if fish is a regular part of your meals, there's no need for it. Likewise, if you spend enough time in the sun, vitamin D supplementation isn't necessary.

My diet consists entirely of meat—no fruits or vegetables at all. The supplements I use are milk thistle, TUDCA, magnesium, and olive oil. I've never felt better.
Click to expand...
Honestly, your location plays a big role — in some places, you simply won't get enough sun exposure to reach healthy vitamin D levels. The Pacific Northwest area of North America is a prime example, especially during fall and winter: the sun's angle plus heavy, persistent cloud cover means the UVB needed for vitamin D synthesis through skin and eyes just isn't there in sufficient amounts.

Every day I use a men's 50+ multivitamin (I'm nowhere near that age, but enclomiphene makes me want added endocrine-supporting vitamins and minerals), vitamin D at 10k i.u. during fall/winter and 4k i.u. in spring/summer, omega-3, CoQ10, and OptiNAD+ (which probably isn't doing much — I'll likely swap it for actual subQ NAD+ down the road).

For sleep or stress, I keep Magnesium Citrate/Threonate, L-Theanine, and Liposomal Apigenin available and take them when needed. Now and then I'll do a pre/probiotic run for a stretch, or go through phases where I eat fermented foods regularly — that seems to really help keep gut health steady. Since I began this approach, I've never had gut problems while on first Tirz and now Reta.

I've tried dozens of supplements over the years and fallen down countless nutritional biology rabbit holes (shoutout 'examine' iykyk), yet my current stack is straightforward, works well, and is easy to stick with — no pill fatigue.

edit nearly left out Creatine, 5g twice a day. Honestly, that stuff is a life-saver.
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You're correct — the pnw region you mention is where I live. Tacoma, Washington is my area. During winter in the pacific northwest, vitamin d is difficult to obtain naturally. It is possible to get it naturally, and I do get plenty that way (I exercise outdoors in the morning, shirtless, throughout winter). Thanks for bringing that up — I was being way too vague.

DC_143C said:

Shittersfull said:

The purpose of supplements is to fill the gaps in what your diet and lifestyle aren't providing. Take omega-3: if fish is a regular part of your meals, there's no need for it. Likewise, if you spend enough time in the sun, vitamin D supplementation isn't necessary.

My diet consists entirely of meat—no fruits or vegetables at all. The supplements I use are milk thistle, TUDCA, magnesium, and olive oil. I've never felt better.
Click to expand...
Honestly, your location plays a big role — in some places, you simply won't get enough sun exposure to reach healthy vitamin D levels. The Pacific Northwest area of North America is a prime example, especially during fall and winter: the sun's angle plus heavy, persistent cloud cover means the UVB needed for vitamin D synthesis through skin and eyes just isn't there in sufficient amounts.

Every day I use a men's 50+ multivitamin (I'm nowhere near that age, but enclomiphene makes me want added endocrine-supporting vitamins and minerals), vitamin D at 10k i.u. during fall/winter and 4k i.u. in spring/summer, omega-3, CoQ10, and OptiNAD+ (which probably isn't doing much — I'll likely swap it for actual subQ NAD+ down the road).

For sleep or stress, I keep Magnesium Citrate/Threonate, L-Theanine, and Liposomal Apigenin available and take them when needed. Now and then I'll do a pre/probiotic run for a stretch, or go through phases where I eat fermented foods regularly — that seems to really help keep gut health steady. Since I began this approach, I've never had gut problems while on first Tirz and now Reta.

I've tried dozens of supplements over the years and fallen down countless nutritional biology rabbit holes (shoutout 'examine' iykyk), yet my current stack is straightforward, works well, and is easy to stick with — no pill fatigue.

edit nearly left out Creatine, 5g twice a day. Honestly, that stuff is a life-saver.
Click to expand...
Magnesium citrate? Or magnesium glycinate, for sleep? Taking the citrate form right before bed would have me pooping the bed.

Pre and probiotics — I agree with those 100%. My job is at a sewage treatment plant. GI issues from work exposure happen regularly for me. To clear out my gi track, I take mag citrate. After that, I use fiber, prebiotic and probiotics to restore it.
 
Shittersfull said:


Magnesium citrate? Or magnesium glycinate, For a sleep? The Citrate version before bed would make me poop the bed.

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Yeah lol, citrate. Personally, I've noticed that GI side effects scale with the dose, and since I never go above 150mg, it's not an issue. If anything, the stool-softening effect could work in your favor on GLP-1's by getting ahead of constipation, ja?

I belong to the minority who reacts paradoxically to glycine—magnesium bis/glycinate actually leaves me with mild anxiety, restlessness, and insomnia, like I'm coming down from too much coffee.

On a side note, magnesium taurate is another one I like. The taurine it contains makes a clear difference when it comes to physical tension and tightness.
 
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