TR60 Reconstituted With 3mL BAC: What Volume Results?

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john_askins

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Has anyone measured, even roughly, how much volume you end up with when TR60 is combined with 3mL of BAC? Without using a big needle to move it into another vial, what method could tell you the total? I tried the dose calculator site, but the result doesn't look right to me (or at least not in my head). Once 3mL goes into 60mg, the volume isn't 3mL anymore.

Thanks!
 
Inside the vial there are 60mg of Tirz — that figure stays put unless testing showed it was overfilled or underfilled, so the quantity of "medicine" itself is fixed. Do you have access to a peptide dosing calculator? With 3ml of Bac added, you'll need to work out how many units each injection requires.
 
Basically. Since 1ml of BAC water weighs 1 gram, then 3ml comes to 3g, which is 3000mg. If you put 60mg into that, the overall total goes up by just 2%. An insulin syringe can't measure that precisely.
 
john_askins said:

Has anyone measured, even roughly, how much volume you end up with when TR60 is combined with 3mL of BAC? Without using a big needle to move it into another vial, what method could tell you the total? I tried the dose calculator site, but the result doesn't look right to me (or at least not in my head). Once 3mL goes into 60mg, the volume isn't 3mL anymore.

Thanks!
Click to expand...
Do you mean the total liquid amount when 60 mg tirz is combined with 3 ml BAC? The result will be slightly above 3 ml, though that small gap shouldn’t be a concern. Like you mentioned, if you truly need the exact figure, the only way is to pull everything into a 5 ml mixing syringe and check the markings. Because that syringe is sterile, re-injecting the contents back into the same vial should be fine.

Suppose you measure something like 3.25 ml — then the math gets more involved. At that level of precision, you’d also have to factor in the batch’s tested overfill, assuming that number is reliable and actually applies to your vial.

My approach would be to keep it simple: 60 mg with 3 ml BAC gives 20 mg/ml. Work out your dose from that. Inject. If the vial ends up giving you 15-30 “extra” units, treat it as a bonus.
 
john_askins said:

Has anyone measured, even roughly, how much volume you end up with when TR60 is combined with 3mL of BAC? Without using a big needle to move it into another vial, what method could tell you the total? I tried the dose calculator site, but the result doesn't look right to me (or at least not in my head). Once 3mL goes into 60mg, the volume isn't 3mL anymore.

Thanks!
Click to expand...
The figure stays at 3mL — once the peptide dissolves, it doesn't change how much BAC you added in any way that matters. Whatever quantity of BAC goes into the vial is the volume you should expect.
 
latviantower said:

john_askins said:

Has anyone measured, even roughly, how much volume you end up with when TR60 is combined with 3mL of BAC? Without using a big needle to move it into another vial, what method could tell you the total? I tried the dose calculator site, but the result doesn't look right to me (or at least not in my head). Once 3mL goes into 60mg, the volume isn't 3mL anymore.

Thanks!
Click to expand...
Do you mean the total liquid amount when 60 mg tirz is combined with 3 ml BAC? The result will be slightly above 3 ml, though that small gap shouldn’t be a concern. Like you mentioned, if you truly need the exact figure, the only way is to pull everything into a 5 ml mixing syringe and check the markings. Because that syringe is sterile, re-injecting the contents back into the same vial should be fine.

Suppose you measure something like 3.25 ml — then the math gets more involved. At that level of precision, you’d also have to factor in the batch’s tested overfill, assuming that number is reliable and actually applies to your vial.

My approach would be to keep it simple: 60 mg with 3 ml BAC gives 20 mg/ml. Work out your dose from that. Inject. If the vial ends up giving you 15-30 “extra” units, treat it as a bonus.
Click to expand...
I'm with you on that. The difference is so tiny that I leave my math as is.
 
john_askins said:

Has anyone measured, even roughly, how much volume you end up with when TR60 is combined with 3mL of BAC? Without using a big needle to move it into another vial, what method could tell you the total? I tried the dose calculator site, but the result doesn't look right to me (or at least not in my head). Once 3mL goes into 60mg, the volume isn't 3mL anymore.

Thanks!
Click to expand...
My guess is that the overall volume lands somewhere around 3.2–3.6mL.
 
DjJoshua said:

john_askins said:

Has anyone measured, even roughly, how much volume you end up with when TR60 is combined with 3mL of BAC? Without using a big needle to move it into another vial, what method could tell you the total? I tried the dose calculator site, but the result doesn't look right to me (or at least not in my head). Once 3mL goes into 60mg, the volume isn't 3mL anymore.

Thanks!
Click to expand...
My guess is that the overall volume lands somewhere around 3.2–3.6mL.
Click to expand...
What's the reasoning behind that figure? Like the replies above said, the volume shift is negligible.
 
The 60 mg of T isn't really tied to how much powder you can see sitting in the vial. And trying to use that weight to figure out volume is a whole other problem.
 
FNG33 said:

The 60 mg of T isn't really tied to how much powder you can see sitting in the vial. And trying to use that weight to figure out volume is a whole other problem.
Click to expand...
right
 
I went down a rabbit hole about peptide volume — not because I care about dosing precision, but because I wanted to figure out how big a 50 year supply of Tirz at 15mg/week would be if it were just the peptide on its own. Turns out it comes to about 90% of the inside space of a regular ping pong ball.

When reconstituted, the actual Tirz at 60mg takes up around 4.4 units, which is .044mL. On top of that, the vial contains binders and other stuff that add volume, along with pore space, which adds nothing.

So if you reconstitute 60mg of Tirz in 3mL, you'd end up with 3.044mL, plus whatever volume the binders and other components of the lyophilized puck contribute.
 
byefatlicia said:

latviantower said:

john_askins said:

Has anyone measured, even roughly, how much volume you end up with when TR60 is combined with 3mL of BAC? Without using a big needle to move it into another vial, what method could tell you the total? I tried the dose calculator site, but the result doesn't look right to me (or at least not in my head). Once 3mL goes into 60mg, the volume isn't 3mL anymore.

Thanks!
Click to expand...
Do you mean the total liquid amount when 60 mg tirz is combined with 3 ml BAC? The result will be slightly above 3 ml, though that small gap shouldn’t be a concern. Like you mentioned, if you truly need the exact figure, the only way is to pull everything into a 5 ml mixing syringe and check the markings. Because that syringe is sterile, re-injecting the contents back into the same vial should be fine.

Suppose you measure something like 3.25 ml — then the math gets more involved. At that level of precision, you’d also have to factor in the batch’s tested overfill, assuming that number is reliable and actually applies to your vial.

My approach would be to keep it simple: 60 mg with 3 ml BAC gives 20 mg/ml. Work out your dose from that. Inject. If the vial ends up giving you 15-30 “extra” units, treat it as a bonus.
Click to expand...
I'm with you on that. The difference is so tiny that I leave my math as is.
Click to expand...
I had this exact conversation with my sister — 100%. She works as an RN, and when she prepares injections, she reconstitutes them in that same manner.
 
Across most products, I've seen little to no change in volume — NAD+ 500mg is the exception. After adding 3ml of BAC, the total comes out to roughly 3.3ml, which is too much for a 3ml cartridge.
 
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