I went ahead and picked up some Tirz, planning to use it for managing my food noise, binge thoughts, and appetite. At 5’8 and 118lbs (53kg), I’m already at a lean weight, but I’m worried that won’t last unless I get things under control. So I wanted to ask everyone here: has anyone used a dose below the standard starting dose for reasons like these, and did it help? The usual recommendation is 2.5mg weekly to begin, but I was considering 1mg per week just to test it out. I don’t want to drop too much weight since I’m not starting off heavy. Thanks!!
Tirz for BED
- Thread starter Oskapig
- Start date
AlexSilver
Explorer
Cagrilintide could be worth considering if your only goal is managing food noise.
eidos
Explorer
At 18, your BMI already sits below the healthy range. Peptides on top of that are a genuine danger to your health.
laansasa
Explorer
I take tirz in microdoses (1mg weekly, divided into 2 doses of 0.5mg each week). I had little weight to shed and was just 4 lbs away from my target. My intention is to continue microdosing for upkeep, so I won't keep worrying about regaining 5-10 lbs.
Many individuals remain on tirz once they hit their goal, so it would be comparable, only for maintenance.
Many individuals remain on tirz once they hit their goal, so it would be comparable, only for maintenance.
miss-sanne
Explorer
You're at a very low weight, so my guess is that a lot of restriction is happening right now, especially if binges are also part of the picture. That loop has to be interrupted — restricting heavily tends to set off even stronger binges later. I lived in that loop for years.
What I'd suggest is eating proper meals 3 x per day, plus decent snacks, EVERY single day, so your brain gets the signal that it's safe.
Just don't let yourself undereat.
A microdose of Tirz could take the edge off food thoughts and noise, but when an underweight body isn't getting enough fuel, that can head somewhere bad. So please be careful.
What I'd suggest is eating proper meals 3 x per day, plus decent snacks, EVERY single day, so your brain gets the signal that it's safe.
Just don't let yourself undereat.
A microdose of Tirz could take the edge off food thoughts and noise, but when an underweight body isn't getting enough fuel, that can head somewhere bad. So please be careful.
Hey, I get where you're coming from, but my only reason for using it is the BED. That's why I'm considering a smaller amount, though if eating becomes too difficult I'll either log everything to ensure I'm getting enough calories or quit altogether. One factor in avoiding Reta was hearing that it raises energy expenditure
. Thanks so much for being upfront and for spending your time to warn me so I know what the risks are! I'm certainly not forgetting that.Hey, I appreciate the worry! Rest assured, I'll be careful to give my body the nutrition it needs. I should clarify that being slim is nothing new for me—I'm a tall Ectomorph with long limbs, same as my parents. The only thing I'm after here is relief for my BED, which got set off by some recent life events. Hope your day goes well
)))
miss-sanne
Explorer
Glad to hear it — tirz will likely be useful for the food noise.Oskapig said:
Hey, I appreciate the worry! Rest assured, I'll be careful to give my body the nutrition it needs. I should clarify that being slim is nothing new for me—I'm a tall Ectomorph with long limbs, same as my parents. The only thing I'm after here is relief for my BED, which got set off by some recent life events. Hope your day goes well
laansasa
Explorer
Tirz has been amazing for me! I'm what you'd call skinny fat, and I only needed to shed 15 lbs. Food noise was never an issue for me, and I could easily stay in a serious calorie deficit — yet I kept putting on weight even after cutting down to just 1 salad daily (400-500 calories)! Years ago, dropping to 900-1200 calories a day did help me lose weight, but that no longer works. I even tried intermittent fasting on a 23/1 schedule and pushed calories down to 500 daily, and the scale still went up!Oskapig said:
What has your experience with micro dosing been like? Did food noise used to be an issue for you, and did it make a difference? Let me know!
My doctors insisted nothing was wrong, but perimenopause was really doing a number on me. Bloodwork came back "within range" despite not being optimal. Thanks to tirz, I can finally shift that stubborn weight and eat the way a normal person does — either 2 small healthy meals daily or 1 regular-sized one. I had cut my food intake so drastically that my doctor told me I'd become catabolic — meaning the more you starve, the more your body clings to fat to survive. So tirz has handed me my life back.
5byfive
Explorer
Down the road, I believe Tirz will be recognized as a legitimate BED treatment. Research into Tirz and addiction is happening as we speak, and in my view BED sits in the addiction bucket rather than alongside the other eating disorders (my day job is in this field).
On a personal level, this is a fight I know well. Constant food noise, plus never feeling satisfied unless I ate way past full, was a lifelong issue for me. Tirz shut all of that down right away. The behaviors themselves I had already sorted out years before, yet my mind never got better until I started Tirz. My advice: begin at a low dose and titrate up gradually until you land on the dose that works best.
That being said, 1) This applies to BED and nothing else. Should other ED problems be present, the picture gets far more complex. Regardless, working with a therapist is something you ought to be doing, and it matters even more when other issues exist. 2) As the saying goes, I am a therapist but I am not your therapist. Nothing here is clinical advice or a sign-off.
On a personal level, this is a fight I know well. Constant food noise, plus never feeling satisfied unless I ate way past full, was a lifelong issue for me. Tirz shut all of that down right away. The behaviors themselves I had already sorted out years before, yet my mind never got better until I started Tirz. My advice: begin at a low dose and titrate up gradually until you land on the dose that works best.
That being said, 1) This applies to BED and nothing else. Should other ED problems be present, the picture gets far more complex. Regardless, working with a therapist is something you ought to be doing, and it matters even more when other issues exist. 2) As the saying goes, I am a therapist but I am not your therapist. Nothing here is clinical advice or a sign-off.
Flash-BCR
Explorer
Do you currently have a doctor overseeing your BED?...If not, it may be worth looking into professional treatment...It would be interesting if GLP-1s were part of treatment....GL!
5byfive
Explorer
For anyone beginning, my suggestion is a 1mg starting point. If a week passes and you notice nothing, increasing is always an option. My approach would be to begin at 1 and raise by .5 each week until effects appear (or until you reach the 2.5mg starting dose). Once you do begin to feel something, I would advise holding at that dose for several weeks, since it will keep accumulating in your system over the following 4 weeks or so.
Stace_wow
Explorer
That's consistently dependable guidance!
lessthanhalf
Explorer
Taking GLP medications when your BMI sits at 18 puts you dangerously near anorexia nervosa, which clinically begins at a BMI of 17. I get that you don't think this applies to you or that you have that kind of issue, but it's worth knowing that people with anorexia commonly feel exactly the same way, so I'd recommend talking to an expert before you go any further. If something meaningfully cuts down how much you eat or binge, it will very likely also make you lose weight. Eventually GLP drugs will probably be prescribed for BED, particularly when obesity is also present, but the evidence isn't really there at this point and I don't believe they're widely used in practice, and I seriously doubt any doctor or therapist would be okay with someone at such a low BMI taking them. In a case of binging with purging, it could maybe be a workable choice, but having professional oversight would be far safer.
For me they definitely do help with BED, which is pretty much resolved now thanks to a carefully planned diet plus GLP drugs, though my starting point was 145kg.
For me they definitely do help with BED, which is pretty much resolved now thanks to a carefully planned diet plus GLP drugs, though my starting point was 145kg.