Stacking cagri with reta: my personal experience

Crowreap

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I've been on reta for roughly 8 weeks, dosing 1 mg each week, and a little while ago I chose to try adding Cagrilintide to the mix. To give some background: I'm already relatively lean and I stay active. I train with weights every day, fit in some cardio, follow OMAD, and I've logged my weight, macros, energy, sleep, and side effects every single day for the whole reta run.

Even before cagri entered the picture, reta was performing very well for me. Appetite control was great, food noise had essentially vanished, hunger stayed very low, and fat loss progressed steadily while my gym performance held steady or even got better. Something I picked up on as time went on was that the GI side effects appeared to creep up gradually, week after week. My energy also tracked closely with how many carbohydrates I ate. With enough carbs, I felt fantastic. On very low carbs, I'd feel drained and slow even with no hunger at all.

This week I started cagri: 133 mcg on Monday, then 133 mcg on Wednesday, putting me at 266 mcg total so far. The most noticeable shift since then hasn't been appetite suppression, since reta had that covered already. What changed most was the gastrointestinal side. I'm getting really powerful fullness and satiety cues. I feel stuffed very fast when eating, and the physical sense of being full lingers for hours. I've had food-related burps long after meals, occasionally carrying into the following day. Bloating and fullness are clearly stronger than with reta alone, my bowel movements appear less frequent, and I frequently feel like I've just eaten when I actually haven't. Thus far, no major nausea or vomiting. I did get a mild headache on 1 day and 1 instance of feeling strangely short of breath and wiped out after a workout, but beyond that I haven't had the heavy fatigue some people describe with cagri.

What I find curious is that my energy still seems tied far more to carbohydrate intake than to appetite. When carbs are low, I'm depleted and sluggish despite zero hunger. When carbs are sufficient, energy is excellent and appetite remains virtually absent. So for me, appetite suppression and energy feel like nearly independent factors.

I'd like to hear from anyone who has stacked cagri with reta. Did the GI effects keep ramping up over time, or did they level off eventually? How long until cag's full effects kicked in for you? Was the first thing you noticed stronger satiety and fullness, or appetite suppression? Did you get more bloating or slower bowel movements? For those combining it with reta, what dose ratio worked best? Did fatigue improve, worsen, or stay the same as time passed? Did anyone find that tiny cag doses were sufficient alongside reta? And lastly, did cag give you benefits that went beyond what reta was already providing?

At the moment I'm actually liking the extra satiety and fullness, but I wonder whether this is typical for the early phase of a cagri and reta stack, or whether these effects usually get much stronger later on. I'd love to hear other people's experiences.
 
Crowreap said:

I've been on reta for roughly 8 weeks, dosing 1 mg each week, and a little while ago I chose to try adding Cagrilintide to the mix. To give some background: I'm already relatively lean and I stay active. I train with weights every day, fit in some cardio, follow OMAD, and I've logged my weight, macros, energy, sleep, and side effects every single day for the whole reta run.

Even before cagri entered the picture, reta was performing very well for me. Appetite control was great, food noise had essentially vanished, hunger stayed very low, and fat loss progressed steadily while my gym performance held steady or even got better. Something I picked up on as time went on was that the GI side effects appeared to creep up gradually, week after week. My energy also tracked closely with how many carbohydrates I ate. With enough carbs, I felt fantastic. On very low carbs, I'd feel drained and slow even with no hunger at all.

This week I started cagri: 133 mcg on Monday, then 133 mcg on Wednesday, putting me at 266 mcg total so far. The most noticeable shift since then hasn't been appetite suppression, since reta had that covered already. What changed most was the gastrointestinal side. I'm getting really powerful fullness and satiety cues. I feel stuffed very fast when eating, and the physical sense of being full lingers for hours. I've had food-related burps long after meals, occasionally carrying into the following day. Bloating and fullness are clearly stronger than with reta alone, my bowel movements appear less frequent, and I frequently feel like I've just eaten when I actually haven't. Thus far, no major nausea or vomiting. I did get a mild headache on 1 day and 1 instance of feeling strangely short of breath and wiped out after a workout, but beyond that I haven't had the heavy fatigue some people describe with cagri.

What I find curious is that my energy still seems tied far more to carbohydrate intake than to appetite. When carbs are low, I'm depleted and sluggish despite zero hunger. When carbs are sufficient, energy is excellent and appetite remains virtually absent. So for me, appetite suppression and energy feel like nearly independent factors.

I'd like to hear from anyone who has stacked cagri with reta. Did the GI effects keep ramping up over time, or did they level off eventually? How long until cag's full effects kicked in for you? Was the first thing you noticed stronger satiety and fullness, or appetite suppression? Did you get more bloating or slower bowel movements? For those combining it with reta, what dose ratio worked best? Did fatigue improve, worsen, or stay the same as time passed? Did anyone find that tiny cag doses were sufficient alongside reta? And lastly, did cag give you benefits that went beyond what reta was already providing?

At the moment I'm actually liking the extra satiety and fullness, but I wonder whether this is typical for the early phase of a cagri and reta stack, or whether these effects usually get much stronger later on. I'd love to hear other people's experiences.
I'm pretty fresh to Reta myself, though I've begun mapping out what maintenance will look like, and cagri has caught my attention. Appreciate you laying out how it went for you
 
My cag should arrive later this week, so I'll be following right after you. Right now I'm on reta at 1.5mg q3d, which puts me close to 4mg per week.

So far, neither appetite nor satiety has impressed me much. I want more of both, which is why I'm adding cag too.

I'm also in decent shape: lifting 3x weekly, cardio 4-5x, and body fat around 12%.
 
nkresho said:

My cag should arrive later this week, so I'll be following right after you. Right now I'm on reta at 1.5mg q3d, which puts me close to 4mg per week.

So far, neither appetite nor satiety has impressed me much. I want more of both, which is why I'm adding cag too.

I'm also in decent shape: lifting 3x weekly, cardio 4-5x, and body fat around 12%.
🖕 😆
 
Why would someone stack cagri on top of Reta when 1mg of Reta is already doing 110% of the work ...
 
nkresho said:

My cag should arrive later this week, so I'll be following right after you. Right now I'm on reta at 1.5mg q3d, which puts me close to 4mg per week.

So far, neither appetite nor satiety has impressed me much. I want more of both, which is why I'm adding cag too.

I'm also in decent shape: lifting 3x weekly, cardio 4-5x, and body fat around 12%.
Good to hear. I'd be interested in hearing how cagri works out for you. If you're sitting at 12% body fat, what are you aiming for? Chasing a shredded look? That's what I'm after. Right now my bathroom scale reads 9%. I want to push even lower and find out how long I can hold it there, since reta plus cagri is honestly a wild combination — it's so simple and requires so little effort that it almost seems absurd. These days it feels like I'm bulking, yet I'm actually cutting aggressively and only taking in 1500 calories per day. This cut on reta and cagri is less of a struggle than bulking or maintaining when I'm not on weight loss drugs lol. So might as well find out how far it can go. Currently looking a bit freaky with veins on my abs and hollow cheeks.

Rezwalker said:

Why would someone stack cagri on top of Reta when 1mg of Reta is already doing 110% of the work ...
Right, adding cagri on top of reta isn't really necessary for me since reta already does the whole job, but I figured I'd test it out just to see what would happen. It blew past what I expected, far more than I ever imagined. I've been on cagri for just 1 week so far. My plan was only 1 week of cagri, but now I'm unsure whether I want to quit it, because I really enjoy that sensation of being extra full. So it's not needed, but I'll make up my mind about whether to keep the cagri going alongside reta. If I do stick with adding cagri, there's definitely no chance I'd bump up the dose for either one, since I'm already getting every effect I wanted and zero sides
 
So right now I'm focused on rebuilding, and while I bulk I really don't want to put on more than 1-2% BF. Getting here took a lot of work, so my plan with reta is to use it as a tool that supports the gains I make going forward by making it simple to adjust how much I eat.

Over the last month I've been bringing carbs back in gradually. The aim is a diet I can stick with for life, with the right calories for my metabolism and enough protein to build and keep muscle. Keto worked really well for shedding the weight, but over time it became a hassle. Bacon and eggs, cheese, pepperoni—I genuinely enjoy those, but it definitely wears thin.

TRT started for me last month, and since then my appetite has been huge and I put on something like 15# in May alone. Much of that early gain was water, though a few pounds were fat as well. Restocking glycogen and keeping it topped up so my lifts stay strong matters a lot to me too. Keto simply wasn't getting that done.

My training is free weights—pressing, squatting, curling, all of it—multiple sets taken to failure in the 12-15 rep range. That happens every other day. On top of that I've added 30-40 mins of LISS (incline treadmill) 4-5 days per week.

Food noise has been a huge problem for me for as long as I can remember. Last year I did a cut with strict Keto and lost around 50#. The food noise never went away, but I could hold it off because I was avoiding carbs completely. Now that exogenous T is in the picture, I'm hungry constantly, like ravenous.

Yeah, so I was the fat kid, and I've always been the fat kid. Not the fattest, but from roughly 10 years old on I was never comfortable taking my shirt off because of my weight. I could demolish an entire birthday cake in one sitting, a tub of ice cream, a bag of chips, candy—oh man, candy is just glorious. Last year I worked my ass off with keto, and there's no way I'll let myself end up back where I was.

For me, adding the Cag to the reta is about fine-tuning my diet precisely, without that sensation that my body still wants food after I've hit my macros. Logically I know exactly what I need to eat to maintain and to build without piling on extra fat. My mouth and stomach, however, have their own agenda and would take me up to 30, 40, 50% body fat within months if I let them.
 
nkresho said:

So right now I'm focused on rebuilding, and while I bulk I really don't want to put on more than 1-2% BF. Getting here took a lot of work, so my plan with reta is to use it as a tool that supports the gains I make going forward by making it simple to adjust how much I eat.

Over the last month I've been bringing carbs back in gradually. The aim is a diet I can stick with for life, with the right calories for my metabolism and enough protein to build and keep muscle. Keto worked really well for shedding the weight, but over time it became a hassle. Bacon and eggs, cheese, pepperoni—I genuinely enjoy those, but it definitely wears thin.

TRT started for me last month, and since then my appetite has been huge and I put on something like 15# in May alone. Much of that early gain was water, though a few pounds were fat as well. Restocking glycogen and keeping it topped up so my lifts stay strong matters a lot to me too. Keto simply wasn't getting that done.

My training is free weights—pressing, squatting, curling, all of it—multiple sets taken to failure in the 12-15 rep range. That happens every other day. On top of that I've added 30-40 mins of LISS (incline treadmill) 4-5 days per week.

Food noise has been a huge problem for me for as long as I can remember. Last year I did a cut with strict Keto and lost around 50#. The food noise never went away, but I could hold it off because I was avoiding carbs completely. Now that exogenous T is in the picture, I'm hungry constantly, like ravenous.

Yeah, so I was the fat kid, and I've always been the fat kid. Not the fattest, but from roughly 10 years old on I was never comfortable taking my shirt off because of my weight. I could demolish an entire birthday cake in one sitting, a tub of ice cream, a bag of chips, candy—oh man, candy is just glorious. Last year I worked my ass off with keto, and there's no way I'll let myself end up back where I was.

For me, adding the Cag to the reta is about fine-tuning my diet precisely, without that sensation that my body still wants food after I've hit my macros. Logically I know exactly what I need to eat to maintain and to build without piling on extra fat. My mouth and stomach, however, have their own agenda and would take me up to 30, 40, 50% body fat within months if I let them.
Right — if your bulk is already where you want it, adding body fat is pointless. On these drugs, and honestly off them too, you can simply recompose; only someone at bodybuilder stage leanness would genuinely need a bulk, and everyone else would be spinning their wheels. But 99% of people are nowhere near stage lean, so recomposition is the smart play. And these drugs make it 10 times simpler to pull off.

nkresho said:

So right now I'm focused on rebuilding, and while I bulk I really don't want to put on more than 1-2% BF. Getting here took a lot of work, so my plan with reta is to use it as a tool that supports the gains I make going forward by making it simple to adjust how much I eat.

Over the last month I've been bringing carbs back in gradually. The aim is a diet I can stick with for life, with the right calories for my metabolism and enough protein to build and keep muscle. Keto worked really well for shedding the weight, but over time it became a hassle. Bacon and eggs, cheese, pepperoni—I genuinely enjoy those, but it definitely wears thin.

TRT started for me last month, and since then my appetite has been huge and I put on something like 15# in May alone. Much of that early gain was water, though a few pounds were fat as well. Restocking glycogen and keeping it topped up so my lifts stay strong matters a lot to me too. Keto simply wasn't getting that done.

My training is free weights—pressing, squatting, curling, all of it—multiple sets taken to failure in the 12-15 rep range. That happens every other day. On top of that I've added 30-40 mins of LISS (incline treadmill) 4-5 days per week.

Food noise has been a huge problem for me for as long as I can remember. Last year I did a cut with strict Keto and lost around 50#. The food noise never went away, but I could hold it off because I was avoiding carbs completely. Now that exogenous T is in the picture, I'm hungry constantly, like ravenous.

Yeah, so I was the fat kid, and I've always been the fat kid. Not the fattest, but from roughly 10 years old on I was never comfortable taking my shirt off because of my weight. I could demolish an entire birthday cake in one sitting, a tub of ice cream, a bag of chips, candy—oh man, candy is just glorious. Last year I worked my ass off with keto, and there's no way I'll let myself end up back where I was.

For me, adding the Cag to the reta is about fine-tuning my diet precisely, without that sensation that my body still wants food after I've hit my macros. Logically I know exactly what I need to eat to maintain and to build without piling on extra fat. My mouth and stomach, however, have their own agenda and would take me up to 30, 40, 50% body fat within months if I let them.
Carbs are non-negotiable. What happens otherwise is that a fairly deep calorie deficit drains your energy as the hours pass. Keto works well for fat loss, no argument, but it's harder to sustain because carbs are so low, so you'll feel flatter.

If food noise has been a real problem for you, adding cagri should take care of it, but please don't cut carbs to get there — otherwise you'll feel half dead, mentally and physically.
 
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