Scientists just regrew knee cartilage.

I hope it's this easy someday, maybe even for hip or other joints as well. I've replaced both my knees and have Arthritis in both hips and everywhere else. I'm probably the outlier here for PPS-Pentosan Polysulfate Sodium, it's an old bladder medication being repurposed for Arthritis. It's been around for horses a hot minute, my dog is on Adequan which is weaker version of it we get through my vet.

There's a company bringing this to market in 26/27, it's in stage III clinical trials now in a few countries. I get mine through my Doctor via telehealth, from a compound pharmacy. I got Arthritis pretty bad, can't sing or dance and can't take Nsaids. So this is the other option for me right now.
 
Can you play any sports with an artificial knee?

I’ve heard a lot of negative things and complaints regarding the surgery itself.

Compared to hip surgery, which generally yields good results, this procedure carries much higher risks.
 
ssmith said:


I really hope so!!!😉

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Stanford Scientists Unveil Breakthrough That Could Eliminate the Need for Knee Replacements by Regrowing Cartilage with a Single Injection



Stanford Medicine published a landmark study in Science (June 12, 2026) showing that blocking the aging enzyme 15-PGDH completely reverses cartilage loss in old mice, prevents post-injury arthritis, and regenerates human knee tissue from replacement surgeries. Here is the full breakthrough.

www.medicaldaily.com
 
Vuja said:


Can you play any sports with an artificial knee?

I’ve heard a lot of negative things and complaints regarding the surgery itself.

Compared to hip surgery, which generally yields good results, this procedure carries much higher risks.

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Yup! I know plenty of old goat skiers that still crush the mountain every day despite both knees getting done.
 
I've had meniscus tears in both knees and went through "clean-up" procedures on each one. My goal is to keep what's left functioning for as many years as I can. Appreciate you posting this — I'll take a look.
 
Vuja said:

Can you play any sports with an artificial knee?

I’ve heard a lot of negative things and complaints regarding the surgery itself.

Compared to hip surgery, which generally yields good results, this procedure carries much higher risks.
Click to expand...
Both of my mother's knees have been replaced — she's 84 — and she still square dances weekly. It isn't really sports, I suppose, but she stays active. Walking beside her through a grocery store, you practically have to jog to stay with her.

Even so, coming back from knee surgery was hard. Word is that it hurts considerably more than hip surgery does, and I find that easy to believe.
 
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