Reta is effective, but the rest appear to do nothing

PorcShanc

PorcShanc

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Hey everyone. For close to 3 months I've been using Reta, BPC, TB500 and GHK. Reta is delivering solid results, and that's the only reason I still have faith in the supplier I came across on this forum. I have zero doubts about how well it works and I'm happy with the weight I've dropped.

As for the others, this is what my dosing looks like...

BPC - 1mg daily (missing around 3 days each month)

GHK - 3mg daily (missing around 3 days each month)

TB500 - front-loaded 3mg 3 times per week for 2 weeks, now on 3mg per week (1 injection weekly)

From these peptides I've felt basically nothing. My skin hasn't improved and my recovery doesn't seem any quicker. Is my dose too low? Or could they simply be bunk?
 
The other 3 are far less noticeable compared to reta. Visible changes may require multiple skin cycles, with 1 skin cycle lasting 4-6 weeks. If you haven't done so yet, I'd suggest capturing "before" photos. For me, the earliest sign was softer skin, along with thinner calluses on my hands and heels that no longer split open the way they did previously. That happened after a few months.
 
bpc was helpful for my back pain caused by protrusions. it also aided with a foot injury. after 2 injections, there was improvement. 500 mg / 10 days.

When it comes to tendon sprain, there is no effect at all
 
I figure there's a reason most of these other peptides never made it as 'pharma drugs'.

They just don't produce reliable results.

Many users report feeling absolutely nothing.

That said, ghk-cu does seem to do something for me — my skin looks improved, rosacea is reduced, and my wrinkles aren't as deep.
 
When I get hurt or feel pain, or when I go through a stretch of training that’s much harder than what I usually do, that’s when I’ll run a BPC/TB cycle.

To me it’s similar to using panadol. It’s not something I use daily. I only reach for it when there’s an actual need.
 
Reta has been shown to be effective in large-scale human trials. It hasn't received approval yet since the stage 3 studies aren't complete, but that will very likely happen soon. Right now it appears to be the most effective anti-obesity medication ever created (that doesn't potentially kill you).

BPC and GHK, when used as systemic treatments (not just applied to the skin), have never been tested in human trials. Whether they are safe or effective for treating any human illness, or for health in general, is unknown.

TB500 has had a small number of very specific human studies, and development continues, so at least there is some safety information for it.

So of 4 peptides, one has solid scientific evidence that it works, one actually works, and the remaining 3 are highly experimental and don't appear to do much. This shouldn't be all that surprising. There is good evidence from cell or animal studies that these 3 peptides may have strong biological effects, but anecdotal reports online of them working are not the same as clinical trial data, whether for safety from unknown adverse effects or for effectiveness. And it's fair to say that nobody really knows exactly what these peptides do.
 
olehandro said:

bpc was helpful for my back pain caused by protrusions. it also aided with a foot injury. after 2 injections, there was improvement. 500 mg / 10 days.

When it comes to tendon sprain, there is no effect at all
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I believe you were referring to 500mcg
 
v2boi said:

olehandro said:

bpc was helpful for my back pain caused by protrusions. it also aided with a foot injury. after 2 injections, there was improvement. 500 mg / 10 days.

When it comes to tendon sprain, there is no effect at all
Click to expand...
I believe you were referring to 500mcg
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Yes)
 
I've done the 'wolverine' stack 2 times because of an injury and... nothing. I also bought a tiny $350 jar of eye cream, since I figured that if it cost THAT much it HAD to work.

This isn't a new thing. Snake oil (and selling it) has been a deeply rooted part of human civilization. Sometimes I wish my brain were stronger and could at least access the placebo effect every now and then, though.
 
olehandro said:

bpc was helpful for my back pain caused by protrusions. it also aided with a foot injury. after 2 injections, there was improvement. 500 mg / 10 days.

When it comes to tendon sprain, there is no effect at all
Click to expand...
Appreciate the response. So you're telling me that 500mg of BPC was used across a 10-day stretch???
 
lessthanhalf said:

Reta has been shown to be effective in large-scale human trials. It hasn't received approval yet since the stage 3 studies aren't complete, but that will very likely happen soon. Right now it appears to be the most effective anti-obesity medication ever created (that doesn't potentially kill you).

BPC and GHK, when used as systemic treatments (not just applied to the skin), have never been tested in human trials. Whether they are safe or effective for treating any human illness, or for health in general, is unknown.

TB500 has had a small number of very specific human studies, and development continues, so at least there is some safety information for it.

So of 4 peptides, one has solid scientific evidence that it works, one actually works, and the remaining 3 are highly experimental and don't appear to do much. This shouldn't be all that surprising. There is good evidence from cell or animal studies that these 3 peptides may have strong biological effects, but anecdotal reports online of them working are not the same as clinical trial data, whether for safety from unknown adverse effects or for effectiveness. And it's fair to say that nobody really knows exactly what these peptides do.
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My expectation was that these compounds would deliver for me in the same way they clearly have for a large number of others. A huge amount of people have shared impressive outcomes with BPC and TB500 when it comes to healing injuries and aiding recovery, and the same goes for GHK regarding its impact on the skin. Hoping that I might experience those same benefits doesn’t strike me as foolish 😅 Calling it something I shouldn’t be surprised by feels like a stretch.
 
KPV gets a thumbs-up from me — my joints feel better and my dermatitis might have improved somewhat. I'm 1 month into what will be a 3 month run. My knees and elbows do get less inflamed, though the relief never lasts. So it's not a fix-all, but I don't believe anyone markets it as one.

A few months back, a Redditor said KPV wiped out her skin issues entirely within 3 months, describing it like a miracle. I haven't reached that point, and it could be overstated, but time will tell.

As for the 3 Russian peptides, I find them fairly potent, and I'm sure the regulars are sick of hearing me go on about them. If you're older and dealing with a brain injury from COVID or a TBI, I'd say they're worth looking into.
 
PorcShanc said:

olehandro said:

bpc was helpful for my back pain caused by protrusions. it also aided with a foot injury. after 2 injections, there was improvement. 500 mg / 10 days.

When it comes to tendon sprain, there is no effect at all
Click to expand...
Appreciate the response. So you're telling me that 500mg of BPC was used across a 10-day stretch???
Click to expand...
No. My earlier figure was incorrect. 500mcg daily, taken across 10 days.
 
When people take peptides that have mostly not been tested in humans, one issue I notice is this: if you're somewhat older, then across the coming 5 to 10 years, a sizable share of those who used them will develop cancer, heart disease, or another serious health problem. There will never be a method to determine whether those peptides brought it about or raised the odds of that outcome—likely they didn't, but certainty is impossible.
 
lessthanhalf said:

When people take peptides that have mostly not been tested in humans, one issue I notice is this: if you're somewhat older, then across the coming 5 to 10 years, a sizable share of those who used them will develop cancer, heart disease, or another serious health problem. There will never be a method to determine whether those peptides brought it about or raised the odds of that outcome—likely they didn't, but certainty is impossible.
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bpc/tb has a very large user base, in my view. The wolverine stack/peptides came onto my radar well before grey anything did. So athletes, crossfitters and gym bros must have been on them for years. Still, you're right that real research is scarce.

Perhaps AI research chemical models will make a bigger jump. I can imagine running a whole simulated "study."
 
A massive amount of individuals post online about using those peptides, yet the reports they share are far too patchy, shaped by self selection, and involve such differing compounds and dosages that no scientifically sound conclusions can ever be drawn from them.

Should a number of users of one specific peptide develop a severe adverse reaction, that kind of signal could still be valuable and merit follow up. For it to emerge from the background noise, though, it would have to be distinctive rather than merely a raised chance of some commonplace issue.

Online accounts also help you gauge which subjective side effects glp drugs might produce, something the trials or manufacturer materials leave unclear.
 
My wife is 62 and has used GLOW for roughly 6 months. It has knocked about 10 yrs off her face and made her hair thicker. These days every one of her friends is on it.

As for me, I use it here and there. Nothing much happens to my face since I am ruggedly handsome.

😀
 
Rolltide61 said:

My wife is 62 and has used GLOW for roughly 6 months. It has knocked about 10 yrs off her face and made her hair thicker. These days every one of her friends is on it.

As for me, I use it here and there. Nothing much happens to my face since I am ruggedly handsome.

😀
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Is her use continuous, or does she cycle it?
 
cheaperseeker said:

Rolltide61 said:

My wife is 62 and has used GLOW for roughly 6 months. It has knocked about 10 yrs off her face and made her hair thicker. These days every one of her friends is on it.

As for me, I use it here and there. Nothing much happens to my face since I am ruggedly handsome.

😀
Click to expand...
Is her use continuous, or does she cycle it?
Click to expand...
I take it for 5 days straight (Monday through Friday), then take the weekends off. I never take entire months off.
 
Rolltide61 said:

cheaperseeker said:

Rolltide61 said:

My wife is 62 and has used GLOW for roughly 6 months. It has knocked about 10 yrs off her face and made her hair thicker. These days every one of her friends is on it.

As for me, I use it here and there. Nothing much happens to my face since I am ruggedly handsome.

😀
Click to expand...
Is her use continuous, or does she cycle it?
Click to expand...
I take it for 5 days straight (Monday through Friday), then take the weekends off. I never take entire months off.
Click to expand...
Rather than doing 2-3 month cycles, I may give that approach a shot. During the weeks I pause, it seems like I'm going backwards.
 
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