UnusualLLama said:
Another 7 days done and dusted!
The numbers
Male
Mid-40's
5'10/178cm
This morning's weight - 75.9.kg/167.3309lbs (previously 76.5.kg/168.6536lbs)
7-day rolling average has dropped 0.8kg/1.7637lbs (slightly more than the week before)
Body fat estimate - 0.3% lower (withings scale, aware it's not the most precise, but I track the direction - and since I began, withings reports a total BF drop of 1.4% and a muscle mass gain of 1.3%)
Resting heart rate average - 46-48 (unchanged from last week)
Blood pressure average - 112/69 (previously 113/71)
Dose - was 1mg reta, bumped it to 2mg yesterday
What I'm noticing
The headline here is that basically nothing shifted compared to last week, everything I wrote then still holds. The one change is that I went from 1mg to 2mg.
This isn't because "it's not doing anything" because it obviously is, I can see it, the numbers confirm it, all signs point that way. The only reason is that the last couple of days before my next pin get a bit tougher.
I'm curious how strongly dose and heart-rate will correlate, and I'll report any sides, but I expect it'll be fine.
Muscle retention rant
I'll probably ramble a bit here, but this has been on my mind a lot this past week or so, particularly after seeing my withings trends consistently show higher lean mass and lower fat numbers.
Taken at face value, that means I'm losing fat and gaining muscle. The fat loss is certain, the muscle gain I'm not sure about, but what I feel more confident in is that I'm not losing muscle. And that was one of my worries with reta. I mentioned it in my first post, I want to get lean while keeping as much muscle as I can, yet everywhere you look reta gets painted as some muscle-devouring compound you could inject into the Hulk to turn him back into Bruce Banner.
I don't believe that's true.
So here are a few things I've been turning over that I want to raise.
1. Every study shows roughly 25-30% lean mass reduction in people on Reta. But that's misleading. The world's reflex seems to be that lean mass = muscle, which isn't correct.
Lean mass covers a lot, and when you're talking about muscle specifically, it isn't even all muscle. A big chunk is water (do a heavy leg session that you feel the next day, I can easily weigh 1kg more than I should), intra-muscular fat, all kinds of things that feed into that number. But we see lean mass in the studies and people instantly think muscle.
2. Back to the studies. Most participants have clinical obesity plus a whole range of other chronic conditions, and from what I can tell, there are plenty of much older people in them too.
This matters because you're dealing not only with people whose metabolism is broken, but also people who probably aren't doing everything possible to limit lean mass loss while in a calorie deficit. Which brings me neatly to the next point.
3. Unless you're on a solid TRT dose, loaded up with SARMS (or similar), or you make a swishing noise when you move because you're pinning so many peptides daily, then anyone in a calorie deficit will lose some lean mass.
Anyone. Everyone.
And that's talking about a normal diet, eating less than you burn.
The human body is great, incredible, it does many things really really well.
But it's not perfect. You can't nail the golden ratio of calories in vs. calories out with ideal muscle stimulus and decimal-accurate protein amounts and expect the body to flip a switch and say "I'm only going to be burning 100% fat now". It's not
THAT good. If you're in a deficit and losing weight, some of it will be lean mass.
Sure, you can tweak things and do the right stuff, and minimise the ratio, but you will lose lean mass. Full stop.
4. This is the point that jumps out at me most, and it's kind of wild that I don't see anyone discussing it now that I've thought about it for a while.
Lean mass to total body weight ratio.
Here's a very rough example to illustrate.
Take someone who's overweight, 50% of their total weight is lean mass, the rest fat.
That person loses weight, say with a GLP. And when they hit their goal, scans show they lost 30% lean mass.
Shocking, right? Or is it?
That person started with a lean mass to total weight ratio of 0.5 (for every lb of weight, 0.5 of it was lean mass, the rest fat).
But at the end, because only 30% of the total weight they lost was lean mass, that means the other 70% was fat.
So now, instead of a ratio of 0.5 it's probably closer to 0.7. They've gone from half their weight being lean mass to 70% of their weight being lean mass. Not only is that healthier, but it will visibly look a ton better, as well as feeling immensely better.
But this ratio never gets highlighted, it's only the "30% lean mass/muscle gone" without the proper nuance it actually needs.
So now that I've rambled way too much, my point is this. I think it's very possible to retain a very good amount of muscle (I said muscle not lean mass for a reason, read above

)on Reta with just a few simple steps.
1. Easy calorie deficit, nothing too extreme. (I understand this might not be the case for everyone, some people have a lot more weight to lose, so you do you).
2. Adequate protein amounts. 1 gram of protein per estimated lb of lean mass (important distinction, lean mass, not muscle).
3. Proper stimulus for the muscles. You don't need to smash the gym 20x per week, just a few workouts where you have 1 or 2 sets in most muscle groups getting within 1-2 reps of failure should do it (I always like to push 1 set to absolute failure on most lifts where viable, don't do this for barbell squats and other compounds etc.)
4. Decent rest and recovery. This is when all of the work you put in is turned into something more than just work. Don't neglect sleep and recovery.
And that's it, rant over. I've typed way too much for something non-work related so I'm out.
Onto the next!