Restless sleep

kroert99

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For years my sleep has been restless, and I'm tired of it. A sleep study isn't something my doctor thinks I need — I don't snore, and my husband has never seen me pause my breathing the way someone with sleep apnea would.

So I want to try out a few peptides aimed at sleep. For the restless legs I get in the evening, she prescribed gabapentin, on the theory that my fidgety legs are what wakes me, though we're not certain. My brain keeps going and I flip around in bed. The more nights this happens, the more anxious I get just about getting into bed. Right now I'm only taking about 7-8mg of Tirz for maintenance. I still have KLOW sitting unmixed and unpinned — the sting makes me a bit nervous. Tesa/ipa is also still unmixed. I'd picked it up to cut body fat ahead of my lipo360, but the instructions said 6 weeks before it kicks in, and my surgery date came up sooner. Now I'm 12wpo and eager to get the most out of my sleep and my workouts.
 
At bedtime, switching my brain off has always been impossible for me. What has helped me most, personally, is putting on a sleep-focused podcast. It shifts my brain into a task-oriented state and pulls my mind away from everything racing around in it. Nothing Much Happens is the one I like best.

I'll admit I was skeptical that something so basic could do anything, but it turned out to be a game changer.
 
I can't tell anyone what to do here, but I'll mention that trazodone helped me deal with the kind of thing you're describing back when I used it. This is an older medication for anxiety that doctors stopped giving for that purpose, since it left people so sleepy and worn out that they'd nod off — meaning it didn't work for daytime. That's the reason it's now mainly handed out for sleep. Unlike most other sleeping pills, it doesn't create a habit. What I noticed was that it didn't exactly silence my mind; rather, once I'd taken it, the random stuff my mind wanted to chew on stopped mattering to me. My mind might still latch onto tomorrow's work tasks (or some other stressful thing waiting for me), but rather than a stress reaction, what came up was indifference. I'm playing it up a little, but my joke was that if the kitchen caught fire, instead of leaping up to douse it, I'd probably just stay put a while longer, seeing as it hadn't reached the bedroom yet.
 
Sleeping has been rougher for me than it used to be — I still get sleep, but I'm waking up more often and earlier. This week I began magnesium glycinate to test whether it makes a difference. Last night was one of the better nights I've had recently, though it's too soon to draw conclusions. I've also begun wearing my watch in bed so I can gather more quantitative sleep data and logs.
 
CandyCap said:

At bedtime, switching my brain off has always been impossible for me. What has helped me most, personally, is putting on a sleep-focused podcast. It shifts my brain into a task-oriented state and pulls my mind away from everything racing around in it. Nothing Much Happens is the one I like best.

I'll admit I was skeptical that something so basic could do anything, but it turned out to be a game changer.
I went ahead and picked up a headband that has speakers built in, so I can try listening to something. I already owned earbuds, but sleeping with them isn't comfortable, so tonight I'll get the headband ready and give it a go. It's so frustrating. Our sleep number bed keeps tabs on just how badly I sleep — around 1.5 to 2 hours of restlessness. Lately it's been hurting my focus and my energy the following day. Ugh!
 
tubby said:

I can't tell anyone what to do here, but I'll mention that trazodone helped me deal with the kind of thing you're describing back when I used it. This is an older medication for anxiety that doctors stopped giving for that purpose, since it left people so sleepy and worn out that they'd nod off — meaning it didn't work for daytime. That's the reason it's now mainly handed out for sleep. Unlike most other sleeping pills, it doesn't create a habit. What I noticed was that it didn't exactly silence my mind; rather, once I'd taken it, the random stuff my mind wanted to chew on stopped mattering to me. My mind might still latch onto tomorrow's work tasks (or some other stressful thing waiting for me), but rather than a stress reaction, what came up was indifference. I'm playing it up a little, but my joke was that if the kitchen caught fire, instead of leaping up to douse it, I'd probably just stay put a while longer, seeing as it hadn't reached the bedroom yet.
A couple of years back I gave that a shot, plus progesterone, which is also said to be beneficial. Nothing. Various marijuana gummies were no help either. On the occasions I could recall actually waking up, I was just high. That felt awful. CBN gummies I have aren't doing anything for me. Hyland Calm Forte isn't helping, and neither is Hyland restful legs. Ativan does the job. It was prescribed to me for anxiety when flying, and it knocks me out. lol
 
woundcarping said:

Sleeping has been rougher for me than it used to be — I still get sleep, but I'm waking up more often and earlier. This week I began magnesium glycinate to test whether it makes a difference. Last night was one of the better nights I've had recently, though it's too soon to draw conclusions. I've also begun wearing my watch in bed so I can gather more quantitative sleep data and logs.
I'm going to give magnesium another shot. I used it before, but perhaps I gave up too soon. I've come across info suggesting DSIP and possibly sermorelin could be beneficial.
 
kroert99 said:

woundcarping said:

Sleeping has been rougher for me than it used to be — I still get sleep, but I'm waking up more often and earlier. This week I began magnesium glycinate to test whether it makes a difference. Last night was one of the better nights I've had recently, though it's too soon to draw conclusions. I've also begun wearing my watch in bed so I can gather more quantitative sleep data and logs.
I'm going to give magnesium another shot. I used it before, but perhaps I gave up too soon. I've come across info suggesting DSIP and possibly sermorelin could be beneficial.
Another thing Epitalon is said to do is shift your circadian rhythm back. I wrapped up a cycle recently, though my main reason was brain health. For me it didn't produce that effect, but I'm also taking Reta, which appears to cut through everything I use apart from Trazodone. On the night of my weekly dose, and the night after, I take half a pill, and that carries me through the week. DSIP has been mentioned by some as helpful too, while others report it did nothing; those who did get results are very enthusiastic about it. I also came across a note that DSIP may interact with ACE inhibitors for HBP, so for now that option is off the table for me.
 
For me, DSIP seems to produce a deeper and more restful night's sleep. I've placed an order for Epitalon and plan to look into it next.
 
tubby said:

I can't tell anyone what to do here, but I'll mention that trazodone helped me deal with the kind of thing you're describing back when I used it. This is an older medication for anxiety that doctors stopped giving for that purpose, since it left people so sleepy and worn out that they'd nod off — meaning it didn't work for daytime. That's the reason it's now mainly handed out for sleep. Unlike most other sleeping pills, it doesn't create a habit. What I noticed was that it didn't exactly silence my mind; rather, once I'd taken it, the random stuff my mind wanted to chew on stopped mattering to me. My mind might still latch onto tomorrow's work tasks (or some other stressful thing waiting for me), but rather than a stress reaction, what came up was indifference. I'm playing it up a little, but my joke was that if the kitchen caught fire, instead of leaping up to douse it, I'd probably just stay put a while longer, seeing as it hadn't reached the bedroom yet.

Years ago I took trazadone as a sleep aid, and for me it was also very effective. Some morning side effects related to being male showed up, though they weren't serious. It was like my teenage years all over again 😁. I don't know why that happened, but it definitely did.

Still, if OP is able to obtain trazadone, it's excellent stuff.

kroert99 said:

miss-sanne said:

Both eptalon and pinealon work well. DSIP might be worth trying too.
I need to look at suppliers for each of these, then decide on one to test.

I'm looking for DSIP, so should I find any vendors that have it in stock, I'll return and share that here.
 
Grogu said:

tubby said:

I can't tell anyone what to do here, but I'll mention that trazodone helped me deal with the kind of thing you're describing back when I used it. This is an older medication for anxiety that doctors stopped giving for that purpose, since it left people so sleepy and worn out that they'd nod off — meaning it didn't work for daytime. That's the reason it's now mainly handed out for sleep. Unlike most other sleeping pills, it doesn't create a habit. What I noticed was that it didn't exactly silence my mind; rather, once I'd taken it, the random stuff my mind wanted to chew on stopped mattering to me. My mind might still latch onto tomorrow's work tasks (or some other stressful thing waiting for me), but rather than a stress reaction, what came up was indifference. I'm playing it up a little, but my joke was that if the kitchen caught fire, instead of leaping up to douse it, I'd probably just stay put a while longer, seeing as it hadn't reached the bedroom yet.

Years ago I took trazadone as a sleep aid, and for me it was also very effective. Some morning side effects related to being male showed up, though they weren't serious. It was like my teenage years all over again 😁. I don't know why that happened, but it definitely did.

Still, if OP is able to obtain trazadone, it's excellent stuff.

kroert99 said:

miss-sanne said:

Both eptalon and pinealon work well. DSIP might be worth trying too.
I need to look at suppliers for each of these, then decide on one to test.

I'm looking for DSIP, so should I find any vendors that have it in stock, I'll return and share that here.
Neither trazadone nor hydroxyzine made much of a difference for me. I'm a mess lol
 
I can relate to what you're going through. My sleep is terrible.

If SSRIs (trazodone) aren't something you'd consider, I've found 3 over the counter supplements that made the biggest difference. I've ranked them by how well they worked.

1.) Glycine. Give it a search and give it a shot. Without question the most effective and safest sleep supplement I've personally used.

2.) Magnesium L theonate. Works well, but it costs more than anything else here.

3.) Magnesium glycinate. Inexpensive and it does the job.

I hope one of these works for you.
 
Epitalon is headed my way; pinealon didn’t work out for me. It left me feeling really drowsy during the day. From what I gather, pinealon isn’t always a good fit for adhd brains, though epitalon ought to be an improvement.
 
For years I've relied on 50mg trazadone to remain asleep. Getting to sleep was never a problem for me. It works right up until it stops working, and for me that happened again roughly 3 months ago. Even after tripling the dose, the issue persisted. Fortunately, my internist sent me to a sleep doctor, and sometime this week I'll be doing a home sleep study.

I could have tried peptides to solve this, but as a 200lbs meat head, I'd rather rule out any medical problem that might have appeared. In particular, non obstructive sleep apnea, given that I don't snore and my wife can confirm that I don't.
 
kroert99 said:

Grogu said:

tubby said:

I can't tell anyone what to do here, but I'll mention that trazodone helped me deal with the kind of thing you're describing back when I used it. This is an older medication for anxiety that doctors stopped giving for that purpose, since it left people so sleepy and worn out that they'd nod off — meaning it didn't work for daytime. That's the reason it's now mainly handed out for sleep. Unlike most other sleeping pills, it doesn't create a habit. What I noticed was that it didn't exactly silence my mind; rather, once I'd taken it, the random stuff my mind wanted to chew on stopped mattering to me. My mind might still latch onto tomorrow's work tasks (or some other stressful thing waiting for me), but rather than a stress reaction, what came up was indifference. I'm playing it up a little, but my joke was that if the kitchen caught fire, instead of leaping up to douse it, I'd probably just stay put a while longer, seeing as it hadn't reached the bedroom yet.

Years ago I took trazadone as a sleep aid, and for me it was also very effective. Some morning side effects related to being male showed up, though they weren't serious. It was like my teenage years all over again 😁. I don't know why that happened, but it definitely did.

Still, if OP is able to obtain trazadone, it's excellent stuff.

kroert99 said:

miss-sanne said:

Both eptalon and pinealon work well. DSIP might be worth trying too.
I need to look at suppliers for each of these, then decide on one to test.

I'm looking for DSIP, so should I find any vendors that have it in stock, I'll return and share that here.
Neither trazadone nor hydroxyzine made much of a difference for me. I'm a mess lol

That's rough — I know exactly how frustrating this is.

From my own experience, tirzepatide has completely wrecked my sleep. The worst stretch came right after I began treatment, though it never really resolved. Early last year I ran a poll in a reddit community, and the anecdotal pattern showed that folks who already struggled with sleep before starting tirzepatide tended to have worse outcomes than those who had no sleep problems beforehand.

If you happen to own a health tracking device, it may be worth checking whether your oxygen levels drop overnight. I deal with sleep apnea myself, and after spending time in a few discussion communities, I noticed that snoring usually goes hand in hand with sleep apnea — but that isn't always the case. Central sleep apnea, for instance, isn't caused by any obstruction or compression of the airway.

I'm not a doc, but what you're describing sounds closer to the anxiety you brought up than to sleep apnea. My suggestion would be to address that first and see whether things improve.
 
Grogu said:

kroert99 said:

Grogu said:

tubby said:

I can't tell anyone what to do here, but I'll mention that trazodone helped me deal with the kind of thing you're describing back when I used it. This is an older medication for anxiety that doctors stopped giving for that purpose, since it left people so sleepy and worn out that they'd nod off — meaning it didn't work for daytime. That's the reason it's now mainly handed out for sleep. Unlike most other sleeping pills, it doesn't create a habit. What I noticed was that it didn't exactly silence my mind; rather, once I'd taken it, the random stuff my mind wanted to chew on stopped mattering to me. My mind might still latch onto tomorrow's work tasks (or some other stressful thing waiting for me), but rather than a stress reaction, what came up was indifference. I'm playing it up a little, but my joke was that if the kitchen caught fire, instead of leaping up to douse it, I'd probably just stay put a while longer, seeing as it hadn't reached the bedroom yet.

Years ago I took trazadone as a sleep aid, and for me it was also very effective. Some morning side effects related to being male showed up, though they weren't serious. It was like my teenage years all over again 😁. I don't know why that happened, but it definitely did.

Still, if OP is able to obtain trazadone, it's excellent stuff.

kroert99 said:

miss-sanne said:

Both eptalon and pinealon work well. DSIP might be worth trying too.
I need to look at suppliers for each of these, then decide on one to test.

I'm looking for DSIP, so should I find any vendors that have it in stock, I'll return and share that here.
Neither trazadone nor hydroxyzine made much of a difference for me. I'm a mess lol

That's rough — I know exactly how frustrating this is.

From my own experience, tirzepatide has completely wrecked my sleep. The worst stretch came right after I began treatment, though it never really resolved. Early last year I ran a poll in a reddit community, and the anecdotal pattern showed that folks who already struggled with sleep before starting tirzepatide tended to have worse outcomes than those who had no sleep problems beforehand.

If you happen to own a health tracking device, it may be worth checking whether your oxygen levels drop overnight. I deal with sleep apnea myself, and after spending time in a few discussion communities, I noticed that snoring usually goes hand in hand with sleep apnea — but that isn't always the case. Central sleep apnea, for instance, isn't caused by any obstruction or compression of the airway.

I'm not a doc, but what you're describing sounds closer to the anxiety you brought up than to sleep apnea. My suggestion would be to address that first and see whether things improve.
Appreciate it. I do own an Apple Watch. Whether it would show an oxygen problem, I'm not certain.

Last night I tried a headband that has speakers built in, plus I grabbed the Headspace app, and I slept really well right up until 3:30 am. After waking, I didn't put on another story, and the next few hours of sleep were terrible.
 
kroert99 said:

Grogu said:

kroert99 said:

Grogu said:

tubby said:

I can't tell anyone what to do here, but I'll mention that trazodone helped me deal with the kind of thing you're describing back when I used it. This is an older medication for anxiety that doctors stopped giving for that purpose, since it left people so sleepy and worn out that they'd nod off — meaning it didn't work for daytime. That's the reason it's now mainly handed out for sleep. Unlike most other sleeping pills, it doesn't create a habit. What I noticed was that it didn't exactly silence my mind; rather, once I'd taken it, the random stuff my mind wanted to chew on stopped mattering to me. My mind might still latch onto tomorrow's work tasks (or some other stressful thing waiting for me), but rather than a stress reaction, what came up was indifference. I'm playing it up a little, but my joke was that if the kitchen caught fire, instead of leaping up to douse it, I'd probably just stay put a while longer, seeing as it hadn't reached the bedroom yet.

Years ago I took trazadone as a sleep aid, and for me it was also very effective. Some morning side effects related to being male showed up, though they weren't serious. It was like my teenage years all over again 😁. I don't know why that happened, but it definitely did.

Still, if OP is able to obtain trazadone, it's excellent stuff.

kroert99 said:

miss-sanne said:

Both eptalon and pinealon work well. DSIP might be worth trying too.
I need to look at suppliers for each of these, then decide on one to test.

I'm looking for DSIP, so should I find any vendors that have it in stock, I'll return and share that here.
Neither trazadone nor hydroxyzine made much of a difference for me. I'm a mess lol

That's rough — I know exactly how frustrating this is.

From my own experience, tirzepatide has completely wrecked my sleep. The worst stretch came right after I began treatment, though it never really resolved. Early last year I ran a poll in a reddit community, and the anecdotal pattern showed that folks who already struggled with sleep before starting tirzepatide tended to have worse outcomes than those who had no sleep problems beforehand.

If you happen to own a health tracking device, it may be worth checking whether your oxygen levels drop overnight. I deal with sleep apnea myself, and after spending time in a few discussion communities, I noticed that snoring usually goes hand in hand with sleep apnea — but that isn't always the case. Central sleep apnea, for instance, isn't caused by any obstruction or compression of the airway.

I'm not a doc, but what you're describing sounds closer to the anxiety you brought up than to sleep apnea. My suggestion would be to address that first and see whether things improve.
Appreciate it. I do own an Apple Watch. Whether it would show an oxygen problem, I'm not certain.

Last night I tried a headband that has speakers built in, plus I grabbed the Headspace app, and I slept really well right up until 3:30 am. After waking, I didn't put on another story, and the next few hours of sleep were terrible.

Whether your Apple Watch can track sleep really comes down to which model you own — it can do it. For me, the issue was the size: the watch felt too bulky, and I never managed to fall asleep while wearing it. That led me to pick up an Oura ring instead, and that one I can actually keep on.

I hadn't come across that app before, so I checked it out, and it seems worth a try. Best of luck! Here's hoping you finally get some rest!
 
kroert99 said:

For years my sleep has been restless, and I'm tired of it. A sleep study isn't something my doctor thinks I need — I don't snore, and my husband has never seen me pause my breathing the way someone with sleep apnea would.

So I want to try out a few peptides aimed at sleep. For the restless legs I get in the evening, she prescribed gabapentin, on the theory that my fidgety legs are what wakes me, though we're not certain. My brain keeps going and I flip around in bed. The more nights this happens, the more anxious I get just about getting into bed. Right now I'm only taking about 7-8mg of Tirz for maintenance. I still have KLOW sitting unmixed and unpinned — the sting makes me a bit nervous. Tesa/ipa is also still unmixed. I'd picked it up to cut body fat ahead of my lipo360, but the instructions said 6 weeks before it kicks in, and my surgery date came up sooner. Now I'm 12wpo and eager to get the most out of my sleep and my workouts.
For me, peptides were not much use when it came to sleeping. Those who seriously pursue better rest tend to build what's called a "sleep stack". Sure, plenty of options give short-term relief, yet a stack appears to hold up over a longer stretch. Lunesta is something I take fairly often, and an anti-histamine occasionally too, but the components I never skip are l-th, melatonin, gaba, saffron, magnesium, agmatine, California poppy. It looks like what helps varies from person to person, though for the first time ever, I'm finally able to get around 7-8 hours of sleep.
 
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