Peptides and Fasting question

[ftv10hb]

When it comes to peptides that need to be dosed while fasted — I'm mainly wondering about GHRP-2 and others like it, since from what I understand, consuming food too soon before or after can mess with insulin response and weaken the peptide's effect — does anyone know or think that "fasting" here would also mean staying away from zero sugar drinks?

I usually drink zero sugar sodas/teas/etc. in the morning or before bed. I've been assuming that since they have no sugar or calories, they don't break the fast and aren't interfering with my peptides. But am I mistaken — do they still cause some kind of insulin response that could get in the way?

If I have to, I'm fine with switching to just water around dosing, but I'd really rather keep my zero sugar drinks if it turns out not to matter lol.

 

[Gr33dyOctopus]

ftv10hb said:

When it comes to peptides that need to be dosed while fasted — I'm mainly wondering about GHRP-2 and others like it, since from what I understand, consuming food too soon before or after can mess with insulin response and weaken the peptide's effect — does anyone know or think that "fasting" here would also mean staying away from zero sugar drinks?

I usually drink zero sugar sodas/teas/etc. in the morning or before bed. I've been assuming that since they have no sugar or calories, they don't break the fast and aren't interfering with my peptides. But am I mistaken — do they still cause some kind of insulin response that could get in the way?

If I have to, I'm fine with switching to just water around dosing, but I'd really rather keep my zero sugar drinks if it turns out not to matter lol.

From what I know, drinks with no sugar and no calories won't break a fast. Honestly, even something that has 20 calories shouldn't break a fast. In my experience, LMNT sticks are the best option while fasting. When I fast for 48 hours, particularly while on glp1, I need that potassium, sodium and magnesium, and those also contain artificial sweeteners

 

[yrrdead]

Gr33dyOctopus said:

ftv10hb said:

When it comes to peptides that need to be dosed while fasted — I'm mainly wondering about GHRP-2 and others like it, since from what I understand, consuming food too soon before or after can mess with insulin response and weaken the peptide's effect — does anyone know or think that "fasting" here would also mean staying away from zero sugar drinks?

I usually drink zero sugar sodas/teas/etc. in the morning or before bed. I've been assuming that since they have no sugar or calories, they don't break the fast and aren't interfering with my peptides. But am I mistaken — do they still cause some kind of insulin response that could get in the way?

If I have to, I'm fine with switching to just water around dosing, but I'd really rather keep my zero sugar drinks if it turns out not to matter lol.

From what I know, drinks with no sugar and no calories won't break a fast. Honestly, even something that has 20 calories shouldn't break a fast. In my experience, LMNT sticks are the best option while fasting. When I fast for 48 hours, particularly while on glp1, I need that potassium, sodium and magnesium, and those also contain artificial sweeteners

For those who enjoy grape flavor, this electrolyte powder is excellent — it's not as handy as LMNT packets, but the formulation is strong and the price is lower.


https://www.amazon.com/dp/B0D3T248FJ


Just a heads-up: coloring made from carrot or beet will leave stains.

 

[chelsea daggerz]

ftv10hb said:

When it comes to peptides that need to be dosed while fasted — I'm mainly wondering about GHRP-2 and others like it, since from what I understand, consuming food too soon before or after can mess with insulin response and weaken the peptide's effect — does anyone know or think that "fasting" here would also mean staying away from zero sugar drinks?

I usually drink zero sugar sodas/teas/etc. in the morning or before bed. I've been assuming that since they have no sugar or calories, they don't break the fast and aren't interfering with my peptides. But am I mistaken — do they still cause some kind of insulin response that could get in the way?

If I have to, I'm fine with switching to just water around dosing, but I'd really rather keep my zero sugar drinks if it turns out not to matter lol.

Drinks with artificial sweeteners barely move insulin, if at all. The systematic review and meta analysis linked here found that after a meal, glucose, insulin, GLP-1, GIP, PYY, ghrelin, and glucagon reactions match those seen with water as the control.

 

[Gr33dyOctopus]

yrrdead said:

Gr33dyOctopus said:

ftv10hb said:

When it comes to peptides that need to be dosed while fasted — I'm mainly wondering about GHRP-2 and others like it, since from what I understand, consuming food too soon before or after can mess with insulin response and weaken the peptide's effect — does anyone know or think that "fasting" here would also mean staying away from zero sugar drinks?

I usually drink zero sugar sodas/teas/etc. in the morning or before bed. I've been assuming that since they have no sugar or calories, they don't break the fast and aren't interfering with my peptides. But am I mistaken — do they still cause some kind of insulin response that could get in the way?

If I have to, I'm fine with switching to just water around dosing, but I'd really rather keep my zero sugar drinks if it turns out not to matter lol.

From what I know, drinks with no sugar and no calories won't break a fast. Honestly, even something that has 20 calories shouldn't break a fast. In my experience, LMNT sticks are the best option while fasting. When I fast for 48 hours, particularly while on glp1, I need that potassium, sodium and magnesium, and those also contain artificial sweeteners

For those who enjoy grape flavor, this electrolyte powder is excellent — it's not as handy as LMNT packets, but the formulation is strong and the price is lower.


https://www.amazon.com/dp/B0D3T248FJ


Just a heads-up: coloring made from carrot or beet will leave stains.

Yeah, I dug into plenty of stuff. When I'm fasting I only take those pricey LMNT packets, so it's not a concern for me.

 

[yrrdead]

Gr33dyOctopus said:

yrrdead said:

Gr33dyOctopus said:

ftv10hb said:

When it comes to peptides that need to be dosed while fasted — I'm mainly wondering about GHRP-2 and others like it, since from what I understand, consuming food too soon before or after can mess with insulin response and weaken the peptide's effect — does anyone know or think that "fasting" here would also mean staying away from zero sugar drinks?

I usually drink zero sugar sodas/teas/etc. in the morning or before bed. I've been assuming that since they have no sugar or calories, they don't break the fast and aren't interfering with my peptides. But am I mistaken — do they still cause some kind of insulin response that could get in the way?

If I have to, I'm fine with switching to just water around dosing, but I'd really rather keep my zero sugar drinks if it turns out not to matter lol.

From what I know, drinks with no sugar and no calories won't break a fast. Honestly, even something that has 20 calories shouldn't break a fast. In my experience, LMNT sticks are the best option while fasting. When I fast for 48 hours, particularly while on glp1, I need that potassium, sodium and magnesium, and those also contain artificial sweeteners

For those who enjoy grape flavor, this electrolyte powder is excellent — it's not as handy as LMNT packets, but the formulation is strong and the price is lower.


https://www.amazon.com/dp/B0D3T248FJ


Just a heads-up: coloring made from carrot or beet will leave stains.

Yeah, I dug into plenty of stuff. When I'm fasting I only take those pricey LMNT packets, so it's not a concern for me.

Chatgpt? When it comes to nutrition, it's nearly as terrible as a PCP. Saying Americans should take in more sodium is about as useful to me as growing another head.

 

[randompersonrandom]

yrrdead said:

Gr33dyOctopus said:

yrrdead said:

Gr33dyOctopus said:

ftv10hb said:

When it comes to peptides that need to be dosed while fasted — I'm mainly wondering about GHRP-2 and others like it, since from what I understand, consuming food too soon before or after can mess with insulin response and weaken the peptide's effect — does anyone know or think that "fasting" here would also mean staying away from zero sugar drinks?

I usually drink zero sugar sodas/teas/etc. in the morning or before bed. I've been assuming that since they have no sugar or calories, they don't break the fast and aren't interfering with my peptides. But am I mistaken — do they still cause some kind of insulin response that could get in the way?

If I have to, I'm fine with switching to just water around dosing, but I'd really rather keep my zero sugar drinks if it turns out not to matter lol.

From what I know, drinks with no sugar and no calories won't break a fast. Honestly, even something that has 20 calories shouldn't break a fast. In my experience, LMNT sticks are the best option while fasting. When I fast for 48 hours, particularly while on glp1, I need that potassium, sodium and magnesium, and those also contain artificial sweeteners

For those who enjoy grape flavor, this electrolyte powder is excellent — it's not as handy as LMNT packets, but the formulation is strong and the price is lower.


https://www.amazon.com/dp/B0D3T248FJ


Just a heads-up: coloring made from carrot or beet will leave stains.

Yeah, I dug into plenty of stuff. When I'm fasting I only take those pricey LMNT packets, so it's not a concern for me.

Chatgpt? When it comes to nutrition, it's nearly as terrible as a PCP. Saying Americans should take in more sodium is about as useful to me as growing another head.

That comparison is a bit harsh—imagine if that extra head had its own consciousness. You would permanently have twice as many thoughts, plus another pair of eyes watching out for any danger you faced. And when a call came in that you truly ought to take but had no desire to, you could just hand the job off to it. The catch, naturally, is that you would first have to settle which head counted as the original and which was merely the spare, and that could get rather complicated.

 

[ftv10hb]

chelsea daggerz said:

ftv10hb said:

When it comes to peptides that need to be dosed while fasted — I'm mainly wondering about GHRP-2 and others like it, since from what I understand, consuming food too soon before or after can mess with insulin response and weaken the peptide's effect — does anyone know or think that "fasting" here would also mean staying away from zero sugar drinks?

I usually drink zero sugar sodas/teas/etc. in the morning or before bed. I've been assuming that since they have no sugar or calories, they don't break the fast and aren't interfering with my peptides. But am I mistaken — do they still cause some kind of insulin response that could get in the way?

If I have to, I'm fine with switching to just water around dosing, but I'd really rather keep my zero sugar drinks if it turns out not to matter lol.

Drinks with artificial sweeteners barely move insulin, if at all. The systematic review and meta analysis linked here found that after a meal, glucose, insulin, GLP-1, GIP, PYY, ghrelin, and glucagon reactions match those seen with water as the control.

Fantastic, that is precisely what I was after, and it is reassuring that the data behind it comes from so many studies too. Thanks!

 

[chelsea daggerz]

chelsea daggerz said:

ftv10hb said:

When it comes to peptides that need to be dosed while fasted — I'm mainly wondering about GHRP-2 and others like it, since from what I understand, consuming food too soon before or after can mess with insulin response and weaken the peptide's effect — does anyone know or think that "fasting" here would also mean staying away from zero sugar drinks?

I usually drink zero sugar sodas/teas/etc. in the morning or before bed. I've been assuming that since they have no sugar or calories, they don't break the fast and aren't interfering with my peptides. But am I mistaken — do they still cause some kind of insulin response that could get in the way?

If I have to, I'm fine with switching to just water around dosing, but I'd really rather keep my zero sugar drinks if it turns out not to matter lol.

Drinks with artificial sweeteners barely move insulin, if at all. The systematic review and meta analysis linked here found that after a meal, glucose, insulin, GLP-1, GIP, PYY, ghrelin, and glucagon reactions match those seen with water as the control.

 

[chelsea daggerz]

ftv10hb said:

chelsea daggerz said:

ftv10hb said:

When it comes to peptides that need to be dosed while fasted — I'm mainly wondering about GHRP-2 and others like it, since from what I understand, consuming food too soon before or after can mess with insulin response and weaken the peptide's effect — does anyone know or think that "fasting" here would also mean staying away from zero sugar drinks?

I usually drink zero sugar sodas/teas/etc. in the morning or before bed. I've been assuming that since they have no sugar or calories, they don't break the fast and aren't interfering with my peptides. But am I mistaken — do they still cause some kind of insulin response that could get in the way?

If I have to, I'm fine with switching to just water around dosing, but I'd really rather keep my zero sugar drinks if it turns out not to matter lol.

Drinks with artificial sweeteners barely move insulin, if at all. The systematic review and meta analysis linked here found that after a meal, glucose, insulin, GLP-1, GIP, PYY, ghrelin, and glucagon reactions match those seen with water as the control.

Fantastic, that is precisely what I was after, and it is reassuring that the data behind it comes from so many studies too. Thanks!

Was the attachment successfully uploaded? When I tapped on it just now, it wouldn't open for me. The title is “The Effect of Non-Nutritive Sweetened Beverages on Postparandial Glycemic and Endocrine Responses” by Zhang et al

 

[ftv10hb]

chelsea daggerz said:

ftv10hb said:

chelsea daggerz said:

ftv10hb said:

When it comes to peptides that need to be dosed while fasted — I'm mainly wondering about GHRP-2 and others like it, since from what I understand, consuming food too soon before or after can mess with insulin response and weaken the peptide's effect — does anyone know or think that "fasting" here would also mean staying away from zero sugar drinks?

I usually drink zero sugar sodas/teas/etc. in the morning or before bed. I've been assuming that since they have no sugar or calories, they don't break the fast and aren't interfering with my peptides. But am I mistaken — do they still cause some kind of insulin response that could get in the way?

If I have to, I'm fine with switching to just water around dosing, but I'd really rather keep my zero sugar drinks if it turns out not to matter lol.

Drinks with artificial sweeteners barely move insulin, if at all. The systematic review and meta analysis linked here found that after a meal, glucose, insulin, GLP-1, GIP, PYY, ghrelin, and glucagon reactions match those seen with water as the control.

Fantastic, that is precisely what I was after, and it is reassuring that the data behind it comes from so many studies too. Thanks!

Was the attachment successfully uploaded? When I tapped on it just now, it wouldn't open for me. The title is “The Effect of Non-Nutritive Sweetened Beverages on Postparandial Glycemic and Endocrine Responses” by Zhang et al

Yes! It came through on my end at least, and I managed to download it