NAD+ shot gone wrong: worst flush ever, nearly called 911

Tbagger

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Before leaving for work today, I did my injections like any other day. I put 50mg of NAD+ into my hip. As soon as the needle came out, a little blood shot out. My first thought was "huh, I've never nicked a vein in my hip before" and I brushed it off. Roughly 15 seconds later, it hit me like a brick wall. Everything went bright white, and my head filled with pressure like it was about to burst. Next, my arms and chest began tingling, which then became a burning sensation. My chest got so tight that breathing became difficult. I became extremely dizzy and had to steady myself because I was starting to fall over. I thought either a massive heart attack or anaphylactic shock was happening. Since my phone was in the living room, I somehow got my drawer open, grabbed my emergency epi-pen, and had it in hand. I figured if I used it, I'd have enough time to reach my phone and call an ambulance. I removed the cap and was on the verge of injecting when the pressure in my head started fading and my breathing got easier. I waited it out for another 15 seconds or so until everything completely passed. The entire episode probably lasted 90 seconds. That was the most insane reaction I've ever had to any peptide, medication, or drug. I assume I accidentally injected into a vein. It really rattled me, and afterward I sat there shaking uncontrollably for a good 5min. I've experienced mild flushing, and even what I considered severe flushing, from NAD+ and a few other peptides before, but nothing close to that. I'm okay now and only got to work a few minutes late. But damn, that terrified me while it was happening! Has anyone else had a crazy reaction that made you reconsider your current peptide research?
 
Good to hear you came out of that fine. What happened to you sounds genuinely frightening. My own take is that going up in small steps is the way to go. As far as I've read, 50 mg of NAD+ is simply too high a dose, since these peptides are short chain amino acids that only give our bodies a gentle push toward doing things on their own through slow signals. So wouldn't staying at smaller amounts be the better approach?
 
Rickcaps said:

Good to hear you came out of that fine. What happened to you sounds genuinely frightening. My own take is that going up in small steps is the way to go. As far as I've read, 50 mg of NAD+ is simply too high a dose, since these peptides are short chain amino acids that only give our bodies a gentle push toward doing things on their own through slow signals. So wouldn't staying at smaller amounts be the better approach?
I’ve been on this for a while, not just starting out. My NAD+ routine had already been scaled back to 50mg, taken 2 times per week. At one point I was doing 500mg weekly. What went wrong wasn’t the amount — I hit a vein by mistake, so it went in IV rather than under the skin like I meant.
 
Could you share additional specifics? Which site did you inject into? Did you use a pen or a syringe? What was the needle length? Thanks.
 
Helpful advice: before you inject, make sure to pull back on the syringe plunger to check for blood return.
 
cat_walk said:

Could you share additional specifics? Which site did you inject into? Did you use a pen or a syringe? What was the needle length? Thanks.
I injected into my right hip using a 31g 5/16” insulin syringe.

DrPEPr said:

Helpful advice: before you inject, make sure to pull back on the syringe plunger to check for blood return.
I know I should, and I did in the past. But after injecting more than 7 times daily for most of a year, I got complacent.
 
It's surprising that a 31g insulin syringe reached a vein — that's not a depth where you'd typically expect to strike one. Good to know you came out of it fine. Since you're aware there are veins sitting near the surface in that subq area, pulling back before injecting there next time would probably be smart?
 
@Tbagger There have been a couple of occasions with subQ NAD+ injections where I struck a vein, an area of muscle with heavy blood flow, or a capillary large enough to trigger a comparable response. The first time it happened, I was absolutely terrified, but it clears up pretty fast, within a few minutes or so. On both occasions, I was rushing and skipped "pinching a good inch" before injecting. My ears begin ringing, my chest tightens, my heart pounds, and my limbs feel like lead. It's almost comparable to a chemically induced stress test, and it resolves just about as fast. Glad you're ok!
 
Ted R said:

@Tbagger There have been a couple of occasions with subQ NAD+ injections where I struck a vein, an area of muscle with heavy blood flow, or a capillary large enough to trigger a comparable response. The first time it happened, I was absolutely terrified, but it clears up pretty fast, within a few minutes or so. On both occasions, I was rushing and skipped "pinching a good inch" before injecting. My ears begin ringing, my chest tightens, my heart pounds, and my limbs feel like lead. It's almost comparable to a chemically induced stress test, and it resolves just about as fast. Glad you're ok!
Knowing others have gone through this too gives me some relief. Lol
 
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