NAD Dosage

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Mduffy18d

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Just getting started—does anyone have thoughts on how much to take and the timing? I'm going to try it out experimentally: 100 MG daily, 2x per week—does that seem correct?
 
Starting out: 25mg, taken 2 times per week, for a period of 2 weeks

Next step: 50mg, taken 2 times per week, spanning 2 weeks

Then: 100mg, taken 2 times per week, continuing for 10 weeks
 
For the first 2 weeks I began with 50mg twice a week, after that I'll raise it to 75 twice a week for 2 weeks, then 100
 
Mduffy18d said:

Just getting started—does anyone have thoughts on how much to take and the timing? I'm going to try it out experimentally: 100 MG daily, 2x per week—does that seem correct?
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NAD+ dosing gets debated quite a bit around here, and you'll find plenty of varying viewpoints if you look through older threads. Try the search feature and take a look.
 
This doc may show up when you search, but in case it doesn't, I've included it here. In my view, the biggest payoff comes from the synergy that happens when it's combined with MOTS-c. The upside is that you're able to begin the NAD+ right away, even before the MOTS-c shows up.
 
PAPoots said:

This doc may show up when you search, but in case it doesn't, I've included it here. In my view, the biggest payoff comes from the synergy that happens when it's combined with MOTS-c. The upside is that you're able to begin the NAD+ right away, even before the MOTS-c shows up.
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Appreciate you sharing that. I'm getting ready to begin NAD+ alongside mots and ss31 too.
 
I can't tell how much of that came from AI versus actual evidence. That said, it does include links to trials and other material, and parts of the reasoning hold up.
 
Use whatever suits you. Begin with 25-50mg to gauge tolerance. For me it isn't very effective, though my mom appears to enjoy it. I gave her 150mg subq immediately from the start, and she experiences no unpleasant reactions.

Keep in mind that NAD depletes methyl groups, somewhat similar to flush niacin but milder. If you're taking a large amount, think about adding methyl b/tmg/phosphatidylcholine as support.
 
After finishing my MOTS-c, I followed the NAD+ protocol I shared before and used it for a number of weeks; the results did gradually diminish. According to my spreadsheet, I went through NAD+ for roughly 5 weeks, until the kit was used up. Later in the summer I'll likely do an Epitalon cycle, then once fall/winter gives me more workout time, I'll repeat the full SS/MOTS-c plus NAD+ cycle.
 
Bigdog0628 said:

For the first 2 weeks I began with 50mg twice a week, after that I'll raise it to 75 twice a week for 2 weeks, then 100
Click to expand...
That's the plan I'm going with.... I'm still sitting at 225
 
Airborne Daddy said:

Bigdog0628 said:

For the first 2 weeks I began with 50mg twice a week, after that I'll raise it to 75 twice a week for 2 weeks, then 100
Click to expand...
That's the plan I'm going with.... I'm still sitting at 225
Click to expand...
Since I haven't been here long enough to use private messages, I figured I'd just drop a line and greet a fellow paratrooper. I was a parachute rigger from OCT 91 to AUG 00. These days I'm a civilian working on T-11's over at the Airborne School on Benning.
 
Mduffy18d said:

Just getting started—does anyone have thoughts on how much to take and the timing? I'm going to try it out experimentally: 100 MG daily, 2x per week—does that seem correct?
Click to expand...
100 mg is far too much for a beginner dose.

Begin at 25mg, then gradually increase
 
As has been said in this thread, you should begin at a lower amount and increase gradually. From what I recall, my starting point was 25mg EOD, and over roughly 8 weeks I built up to 100mg each day. In the end I switched to 1000mg oral NR taken daily, since that approach works better for lifting baseline cellular NAD levels across time. It is more steady. Injecting NAD gives a more immediate, short-lived delivery along with a short-lived result.


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