ColdBubbles
Explorer
I got the chance not long ago to use a V2 peptide pen for my KLOW, dosing it 5 days each week, and figured sharing how my first month went could be useful for anyone thinking about going the pen route. YMMV!!!
The pen I received was a standard generic V2 from amazon, priced at $39. I bought sterile 3ml cartridges plus a box of 32g pen tips. Since I'm using it for KLOW80, I chose the 8mm length, because with KLOW I've noticed longer needles give me less ISR. If GLP-1s were what I was dosing, I'd go with 6mm tips.
Testing the dosing accuracy was the very first thing I did. Generic pens have a reputation for being notoriously inaccurate, so I figured a test was worthwhile. I used BAC water for the test, though looking back, plain water would probably have worked too. YouTube has plenty of videos showing how to test, but my approach was simpler: fill the cartridge with 2ml water using a luer-lock syringe, attach a tip, hold the pen pointing straight up, purge all the air until liquid began emerging from the tip, then take the tip off. After that I put an insulin syringe into the cartridge tip, dialed the dose, and injected into the syringe to measure what was dispensed. I checked a number of different doses, and on every setting my particular pen came out within 1/2 unit of accuracy. Satisfied with my dosing accuracy, I threw out that cartridge, loaded a fresh one with my KLOW80, purged the air, sterilized, and I was all set!
First off, that 32g needle is unbelievably pain-free! At first I wasn't even sure the injection had happened. I truly felt nothing going in, not even the slightest pinch. For my reta I use 31g insulin needles, and those are pretty good, but the smaller needle plus not having to pierce the vial with it first makes a huge difference. With KLOW via syringe, I typically used to get a very slight ISR as a faint one-inch reddish circle (bruise?) that took several days to fade. With the pen, I get that circle only about half the time, and it fades within a day or two.
Temperature was the next thing I tackled. Bringing an entire cartridge of peptides to room temp 5 times a week didn't appeal to me for obvious reasons, so I tested how well I tolerated cold injections. My starting point was leaving it out for 8 minutes, then I cut the time by 2 minutes daily. In the end the cooler temps didn't bother me even slightly, and these days I inject straight from the fridge. Worth noting: I'm among the lucky ones who don't feel the "spicy" burn of GHK-cu, so your experience may be different. What I'm getting at is that testing your own tolerance in stages is easy.
Last, my take on auto-inject versus manual inject pens such as the V2. Spring-loaded auto pens are something I personally do NOT like. The Wegovy auto-pens are the only ones I've used, but the spring action just freaks me out. I prefer the control of a plunger I can push at whatever rate I want. That's what the V2 pens let you do.
The pen I received was a standard generic V2 from amazon, priced at $39. I bought sterile 3ml cartridges plus a box of 32g pen tips. Since I'm using it for KLOW80, I chose the 8mm length, because with KLOW I've noticed longer needles give me less ISR. If GLP-1s were what I was dosing, I'd go with 6mm tips.
Testing the dosing accuracy was the very first thing I did. Generic pens have a reputation for being notoriously inaccurate, so I figured a test was worthwhile. I used BAC water for the test, though looking back, plain water would probably have worked too. YouTube has plenty of videos showing how to test, but my approach was simpler: fill the cartridge with 2ml water using a luer-lock syringe, attach a tip, hold the pen pointing straight up, purge all the air until liquid began emerging from the tip, then take the tip off. After that I put an insulin syringe into the cartridge tip, dialed the dose, and injected into the syringe to measure what was dispensed. I checked a number of different doses, and on every setting my particular pen came out within 1/2 unit of accuracy. Satisfied with my dosing accuracy, I threw out that cartridge, loaded a fresh one with my KLOW80, purged the air, sterilized, and I was all set!
First off, that 32g needle is unbelievably pain-free! At first I wasn't even sure the injection had happened. I truly felt nothing going in, not even the slightest pinch. For my reta I use 31g insulin needles, and those are pretty good, but the smaller needle plus not having to pierce the vial with it first makes a huge difference. With KLOW via syringe, I typically used to get a very slight ISR as a faint one-inch reddish circle (bruise?) that took several days to fade. With the pen, I get that circle only about half the time, and it fades within a day or two.
Temperature was the next thing I tackled. Bringing an entire cartridge of peptides to room temp 5 times a week didn't appeal to me for obvious reasons, so I tested how well I tolerated cold injections. My starting point was leaving it out for 8 minutes, then I cut the time by 2 minutes daily. In the end the cooler temps didn't bother me even slightly, and these days I inject straight from the fridge. Worth noting: I'm among the lucky ones who don't feel the "spicy" burn of GHK-cu, so your experience may be different. What I'm getting at is that testing your own tolerance in stages is easy.
Last, my take on auto-inject versus manual inject pens such as the V2. Spring-loaded auto pens are something I personally do NOT like. The Wegovy auto-pens are the only ones I've used, but the spring action just freaks me out. I prefer the control of a plunger I can push at whatever rate I want. That's what the V2 pens let you do.