upnorth8 said:
Spork said:
upnorth8 said:
Just my 2 cents, as someone who has run both tirz and reta (and dropped over 100 pounds). Tirz acts faster and, for most people it seems, does more for food noise.
That really grabs my attention, since the same point keeps coming up repeatedly, and still... what explains retatrutide studies showing greater weight reduction compared with tirzepatide?
From what people report, though, tirzepatide does seem to do a better job at quieting food noise and suppressing appetite.
Could it be the glucagon agonist — that third one in reta — which ramps up how quickly your metabolism burns?
I'm only speculating here, but reta's gradual buildup means it appears to need a lot more time before the food noise actually settles down. When I introduced reta, I attempted to lower my tirz dose, and that turned out to be impossible for me. On top of that, reta gives me something of an anxious sensation, at least in my case. I ought to begin logging it so I can figure out how it lines up with my levels according to shotsy. That's why I'm increasing so gradually. Since late Jan I've been using reta, and I'm still only at 2mg every 5 days (which works out to roughly 2.8mg every 7, if my math is right). A lot of other folks seem to stack additional peps, cagri maybe, to deal with food noise while on reta, but I've got a stash of tirz that's just sitting there creeping past its BUD, so I'll keep using that instead.