How do I choose the size of the vials to order?

[ShimrodsPhial]

I'll be placing my first order of Retatrutide this week. There are 35 kg to shift, and a lot of that is visceral fat. That works out at roughly 32% of my current body weight. From what I gather this can take as long as two years with Retatrutide, and the dose determines how it goes.

From the experiences I've read, people describe starting at around 1 mg, then going to 2 mg for 4 weeks, 4 mg for 4 weeks, and so on. Whether I'll push up to 6 or 8 mg I haven't decided. I believe I've grasped how to titrate properly and how to watch for side effects.

Where I'm stuck: buying 10 mg vials works nicely for the first month, but after that dividing them by 4 no longer comes out even. How do you all deal with it?

If I go for 20 mg vials instead, half of each one gets thrown out after the first month. It's only $10, but waste bothers me.

Have I missed something? Thanks.

 

[BigRed1]

Starting on 10mg and moving to bigger sizes as you titrate up strikes me as sensible. I did the reverse - bought the bigger ones because it's "better value" - and then ended up binning some because they lasted too long.

I'm on week 11 and can barely handle 3mg at the moment, so titrating up could take you a while. You don't really know until you try it.

As for the "can't divide by 4" problem, that's fine. Just finish whatever is left in a vial, then move to the next vial to make up your full dose for the week.

 

[Pocket]

Big Red has it right. Get a kit at the smaller dosage and work upwards from there. That said, plenty of members run a vial past the recommended 28 days with few issues. So it comes down to how much risk you'll accept against how much reta you're prepared to lose.

 

[Romulusguy]

Opinions will differ on this: here is mine What isn't really up for debate is that higher concentrations (i.e. 60mg vs. 10mg) give you more mg for your money. With that in mind....

You can reconstitute several smaller bottles into one highly concentrated vial. As an example, take 3ML and reconstitute a 10MG reta with it, then use that reconstituted reta to reconstitute ANOTHER bottle of 10mg, giving you 20MG reta/3ml Bac in total. So if you titrate faster than expected, or fast enough that a 10MG bottle no longer covers you, you can just combine the smaller bottles into a higher concentration.

If your problem is the opposite one - say you're using 1mg a week from a 10mg bottle - I'd expect most people (myself included) to back using that bottle for up to 8 weeks. Theoretically that gets you 8 doses out of your 10mg vial @ 1mg a week (or 8 weeks/.2 months).

Here is what I would recommend for you.

Set yourself a "planned" titration schedule, but let your body decide the real one once you're underway (i.e. how do you feel). Say you begin at 1mg for the first 2 weeks, plan to titrate to 2mg for the next 4 weeks, then leave yourself room to nitrate up to 8mg for the following several months (this is of course JUST AN EXAMPLE, not a schedule I'm recommending or that comes from any expert or known protocol lol). So buying a kit of 10mg RETA, then several kits of 20mg or 30mg Reta to cover later titrations, is easy enough (remember, vials combine, so the 10mg ones are usable if you do titrate up quickly). Stay low and those 10MG vials will serve you for a long time before you move up (or just save them for a future titration, and order more of the lower concentrations once your original supply runs out); go higher and you have a solid supply to cover your expansion.

 

[ShimrodsPhial]

Romulusguy said:

Opinions will differ on this: here is mine What isn't really up for debate is that higher concentrations (i.e. 60mg vs. 10mg) give you more mg for your money. With that in mind....

You can reconstitute several smaller bottles into one highly concentrated vial. As an example, take 3ML and reconstitute a 10MG reta with it, then use that reconstituted reta to reconstitute ANOTHER bottle of 10mg, giving you 20MG reta/3ml Bac in total. So if you titrate faster than expected, or fast enough that a 10MG bottle no longer covers you, you can just combine the smaller bottles into a higher concentration.

If your problem is the opposite one - say you're using 1mg a week from a 10mg bottle - I'd expect most people (myself included) to back using that bottle for up to 8 weeks. Theoretically that gets you 8 doses out of your 10mg vial @ 1mg a week (or 8 weeks/.2 months).

Here is what I would recommend for you.

Set yourself a "planned" titration schedule, but let your body decide the real one once you're underway (i.e. how do you feel). Say you begin at 1mg for the first 2 weeks, plan to titrate to 2mg for the next 4 weeks, then leave yourself room to nitrate up to 8mg for the following several months (this is of course JUST AN EXAMPLE, not a schedule I'm recommending or that comes from any expert or known protocol lol). So buying a kit of 10mg RETA, then several kits of 20mg or 30mg Reta to cover later titrations, is easy enough (remember, vials combine, so the 10mg ones are usable if you do titrate up quickly). Stay low and those 10MG vials will serve you for a long time before you move up (or just save them for a future titration, and order more of the lower concentrations once your original supply runs out); go higher and you have a solid supply to cover your expansion.

That's really clear, thanks.

A 10 mg kit it is then, and in a couple of months I'll work out what to order next.

 

[pier_man0909]

ShimrodsPhial said:

I'll be placing my first order of Retatrutide this week. There are 35 kg to shift, and a lot of that is visceral fat. That works out at roughly 32% of my current body weight. From what I gather this can take as long as two years with Retatrutide, and the dose determines how it goes.

From the experiences I've read, people describe starting at around 1 mg, then going to 2 mg for 4 weeks, 4 mg for 4 weeks, and so on. Whether I'll push up to 6 or 8 mg I haven't decided. I believe I've grasped how to titrate properly and how to watch for side effects.

Where I'm stuck: buying 10 mg vials works nicely for the first month, but after that dividing them by 4 no longer comes out even. How do you all deal with it?

If I go for 20 mg vials instead, half of each one gets thrown out after the first month. It's only $10, but waste bothers me.

Have I missed something? Thanks.

Not a recommendation, just a couple of things worth reading up on. A friend of mine at work began reta at .5mg. His reasoning was to reduce the chance of side effects. The reta suited him well and he never went beyond a 2mg dose across 6 months. That's simply how it went for him. Basing your dose on how your own body responds rather than on a calendar might serve you better.

You mentioned visceral fat. Accurate or not, studies have shown tesamorelin is good at reducing it. It even holds fda approval under the name "egrifta" for treating visceral fat. It could be a useful addition alongside the reta if visceral fat is the worry.

 

[anhydrous]

Solid advice so far, but I'd stress that there's no way to predict your own response accurately. 1mg a week could feel like nothing at all, or it could hit you hard. You simply don't know until you try, so I'd plan on tailoring your usage to what you need.

 

[BNLFL]

Start at 2mg, using a 10mg vial reconstituted with 1ml BAC, and run that for 4 weeks. That covers 10 weeks of shots. My own limit is on how long something sits reconed in the fridge, but you'll be at 4mgs within 4 weeks. After that the mg disappear much faster. Trust me, that 10mg kit will be gone in no time. Before long you'll be hunting R60's. Around my house a 10mg vial is one shot.

 

[Vriende]

pier_man0909 said:

ShimrodsPhial said:

I'll be placing my first order of Retatrutide this week. There are 35 kg to shift, and a lot of that is visceral fat. That works out at roughly 32% of my current body weight. From what I gather this can take as long as two years with Retatrutide, and the dose determines how it goes.

From the experiences I've read, people describe starting at around 1 mg, then going to 2 mg for 4 weeks, 4 mg for 4 weeks, and so on. Whether I'll push up to 6 or 8 mg I haven't decided. I believe I've grasped how to titrate properly and how to watch for side effects.

Where I'm stuck: buying 10 mg vials works nicely for the first month, but after that dividing them by 4 no longer comes out even. How do you all deal with it?

If I go for 20 mg vials instead, half of each one gets thrown out after the first month. It's only $10, but waste bothers me.

Have I missed something? Thanks.

Not a recommendation, just a couple of things worth reading up on. A friend of mine at work began reta at .5mg. His reasoning was to reduce the chance of side effects. The reta suited him well and he never went beyond a 2mg dose across 6 months. That's simply how it went for him. Basing your dose on how your own body responds rather than on a calendar might serve you better.

You mentioned visceral fat. Accurate or not, studies have shown tesamorelin is good at reducing it. It even holds fda approval under the name "egrifta" for treating visceral fat. It could be a useful addition alongside the reta if visceral fat is the worry.

Plenty of people choose to take it gently and go the cautious route, to steer clear of constipation, explosive diarrhea or other unexpected side effects.

I was going to warn you that BNLFL would turn up saying you should definitely start at 2mg.

Well, I see he got here first -- Hi BNLFL! ;-)

He's adventurous and it worked out for him, but some of us do better on smaller doses, like Pier's friend above. I'm months in and still working through my first 12mg/vial kit.

My next kit may well be the same.

 

[Vriende]

A similar thread running at the same time --




Reta Question: RT 10 against larger MG vials



Hi all, I've just joined and already picked up SO MUCH from everyone - thank you! I'm hoping this post stays within the rules (I did search the sub before posting), but my first reta purchase is coming up and I'd love someone to explain why would you buy higher than RT10...

GLP1Chat.com

 

[jpru2001]

Same take as the others — 4-8 weeks per vial is the sweet spot. Lots of good input in this thread.

 

[Shittersfull]

Plenty of solid input in this thread. My first vial came from a mate — an r30 — and I dove straight in at 2mg, then moved up to 4mg somewhere around the 6 week mark. Ran it down to empty. The official line is 28 days for a reconstituted vial, though plenty of folk stretch it well past that. Stay hygienic, and once you push the timeline the grade of your bac water counts for a lot more.

 

[BNLFL]

Shittersfull said:

Plenty of solid input in this thread. My first vial came from a mate — an r30 — and I dove straight in at 2mg, then moved up to 4mg somewhere around the 6 week mark. Ran it down to empty. The official line is 28 days for a reconstituted vial, though plenty of folk stretch it well past that. Stay hygienic, and once you push the timeline the grade of your bac water counts for a lot more.

Yep — I'm an 8 week guy, and I'd push to 10 when it's warranted. I do my best to plan so I never hit 10 weeks.

 

[Skidude]

BNLFL said:

Shittersfull said:

Plenty of solid input in this thread. My first vial came from a mate — an r30 — and I dove straight in at 2mg, then moved up to 4mg somewhere around the 6 week mark. Ran it down to empty. The official line is 28 days for a reconstituted vial, though plenty of folk stretch it well past that. Stay hygienic, and once you push the timeline the grade of your bac water counts for a lot more.

Yep — I'm an 8 week guy, and I'd push to 10 when it's warranted. I do my best to plan so I never hit 10 weeks.

6-8 was my range for most of the Tirz titration

EDIT

That said, I've never bought it by the barrel

 

[Bahookie]

Fat Scientist has a tool that makes it easy to work out how to finish one vial on a given dose and then step onto the next vial at a different strength (10mg for me, then 30mg). I found it really useful.

Vial Transition Dosage Calculator | Fat Scientist - GLP-1 Dosage Calculators & Guides



Simple tool to help you transition between GLP-1 vials of different concentrations safely. Calculate the correct units from both vials to maintain your prescribed dose.

Image unavailable


www.fatscientist.com

 

[BNLFL]

Bahookie said:

Fat Scientist has a tool that makes it easy to work out how to finish one vial on a given dose and then step onto the next vial at a different strength (10mg for me, then 30mg). I found it really useful.



View attachment 8702



Vial Transition Dosage Calculator | Fat Scientist - GLP-1 Dosage Calculators & Guides



Simple tool to help you transition between GLP-1 vials of different concentrations safely. Calculate the correct units from both vials to maintain your prescribed dose.

Image unavailable


www.fatscientist.com

This is the one I use.

Injection Shop - Reconstitution Calculator



A free calculator for working out how to reconstitute lyophilized peptide vials, whether with bacteriostatic (BAC) water, sterile water or bacteriostatic sodium chloride NaCl. The same site also carries peptide and injection supplies, testosterone and hormone therapy, glp-1 and compounded semaglutide...

Image unavailable


calc.injectionshop.com

 

[Riviera]

ShimrodsPhial said:

Romulusguy said:

Opinions will differ on this: here is mine What isn't really up for debate is that higher concentrations (i.e. 60mg vs. 10mg) give you more mg for your money. With that in mind....

You can reconstitute several smaller bottles into one highly concentrated vial. As an example, take 3ML and reconstitute a 10MG reta with it, then use that reconstituted reta to reconstitute ANOTHER bottle of 10mg, giving you 20MG reta/3ml Bac in total. So if you titrate faster than expected, or fast enough that a 10MG bottle no longer covers you, you can just combine the smaller bottles into a higher concentration.

If your problem is the opposite one - say you're using 1mg a week from a 10mg bottle - I'd expect most people (myself included) to back using that bottle for up to 8 weeks. Theoretically that gets you 8 doses out of your 10mg vial @ 1mg a week (or 8 weeks/.2 months).

Here is what I would recommend for you.

Set yourself a "planned" titration schedule, but let your body decide the real one once you're underway (i.e. how do you feel). Say you begin at 1mg for the first 2 weeks, plan to titrate to 2mg for the next 4 weeks, then leave yourself room to nitrate up to 8mg for the following several months (this is of course JUST AN EXAMPLE, not a schedule I'm recommending or that comes from any expert or known protocol lol). So buying a kit of 10mg RETA, then several kits of 20mg or 30mg Reta to cover later titrations, is easy enough (remember, vials combine, so the 10mg ones are usable if you do titrate up quickly). Stay low and those 10MG vials will serve you for a long time before you move up (or just save them for a future titration, and order more of the lower concentrations once your original supply runs out); go higher and you have a solid supply to cover your expansion.

That's really clear, thanks.

A 10 mg kit it is then, and in a couple of months I'll work out what to order next.

Yes, the 10 mg kits are a very safe bet, and starting off at 1mg/week makes for a soft intro. For me it was 1.75mg / wk, then up in steps of roughly .25mg / wk, and after 7 weeks I'm 23 lb lighter and settled somewhere around 3.25-3.5mg / wk. I split that into 3 parts, taking one every other day, which has worked beautifully. Your mileage may vary.

I doubt you'll be waiting a few years. Nothing I've come across comes as close to a miracle as Reta. Enjoy it!

 

[BNLFL]

Riviera said:

ShimrodsPhial said:

Romulusguy said:

Opinions will differ on this: here is mine What isn't really up for debate is that higher concentrations (i.e. 60mg vs. 10mg) give you more mg for your money. With that in mind....

You can reconstitute several smaller bottles into one highly concentrated vial. As an example, take 3ML and reconstitute a 10MG reta with it, then use that reconstituted reta to reconstitute ANOTHER bottle of 10mg, giving you 20MG reta/3ml Bac in total. So if you titrate faster than expected, or fast enough that a 10MG bottle no longer covers you, you can just combine the smaller bottles into a higher concentration.

If your problem is the opposite one - say you're using 1mg a week from a 10mg bottle - I'd expect most people (myself included) to back using that bottle for up to 8 weeks. Theoretically that gets you 8 doses out of your 10mg vial @ 1mg a week (or 8 weeks/.2 months).

Here is what I would recommend for you.

Set yourself a "planned" titration schedule, but let your body decide the real one once you're underway (i.e. how do you feel). Say you begin at 1mg for the first 2 weeks, plan to titrate to 2mg for the next 4 weeks, then leave yourself room to nitrate up to 8mg for the following several months (this is of course JUST AN EXAMPLE, not a schedule I'm recommending or that comes from any expert or known protocol lol). So buying a kit of 10mg RETA, then several kits of 20mg or 30mg Reta to cover later titrations, is easy enough (remember, vials combine, so the 10mg ones are usable if you do titrate up quickly). Stay low and those 10MG vials will serve you for a long time before you move up (or just save them for a future titration, and order more of the lower concentrations once your original supply runs out); go higher and you have a solid supply to cover your expansion.

That's really clear, thanks.

A 10 mg kit it is then, and in a couple of months I'll work out what to order next.

Yes, the 10 mg kits are a very safe bet, and starting off at 1mg/week makes for a soft intro. For me it was 1.75mg / wk, then up in steps of roughly .25mg / wk, and after 7 weeks I'm 23 lb lighter and settled somewhere around 3.25-3.5mg / wk. I split that into 3 parts, taking one every other day, which has worked beautifully. Your mileage may vary.

I doubt you'll be waiting a few years. Nothing I've come across comes as close to a miracle as Reta. Enjoy it!

So you're doing 3 shots a week, and all of them together only add up to 1mg a week?

Can't say I follow the logic, but each to their own. Mine is 10mg a week, in one shot.

 

[Skidude]

BNLFL said:

Riviera said:

ShimrodsPhial said:

Romulusguy said:

Opinions will differ on this: here is mine What isn't really up for debate is that higher concentrations (i.e. 60mg vs. 10mg) give you more mg for your money. With that in mind....

You can reconstitute several smaller bottles into one highly concentrated vial. As an example, take 3ML and reconstitute a 10MG reta with it, then use that reconstituted reta to reconstitute ANOTHER bottle of 10mg, giving you 20MG reta/3ml Bac in total. So if you titrate faster than expected, or fast enough that a 10MG bottle no longer covers you, you can just combine the smaller bottles into a higher concentration.

If your problem is the opposite one - say you're using 1mg a week from a 10mg bottle - I'd expect most people (myself included) to back using that bottle for up to 8 weeks. Theoretically that gets you 8 doses out of your 10mg vial @ 1mg a week (or 8 weeks/.2 months).

Here is what I would recommend for you.

Set yourself a "planned" titration schedule, but let your body decide the real one once you're underway (i.e. how do you feel). Say you begin at 1mg for the first 2 weeks, plan to titrate to 2mg for the next 4 weeks, then leave yourself room to nitrate up to 8mg for the following several months (this is of course JUST AN EXAMPLE, not a schedule I'm recommending or that comes from any expert or known protocol lol). So buying a kit of 10mg RETA, then several kits of 20mg or 30mg Reta to cover later titrations, is easy enough (remember, vials combine, so the 10mg ones are usable if you do titrate up quickly). Stay low and those 10MG vials will serve you for a long time before you move up (or just save them for a future titration, and order more of the lower concentrations once your original supply runs out); go higher and you have a solid supply to cover your expansion.

That's really clear, thanks.

A 10 mg kit it is then, and in a couple of months I'll work out what to order next.

Yes, the 10 mg kits are a very safe bet, and starting off at 1mg/week makes for a soft intro. For me it was 1.75mg / wk, then up in steps of roughly .25mg / wk, and after 7 weeks I'm 23 lb lighter and settled somewhere around 3.25-3.5mg / wk. I split that into 3 parts, taking one every other day, which has worked beautifully. Your mileage may vary.

I doubt you'll be waiting a few years. Nothing I've come across comes as close to a miracle as Reta. Enjoy it!

So you're doing 3 shots a week, and all of them together only add up to 1mg a week?

Can't say I follow the logic, but each to their own. Mine is 10mg a week, in one shot.

Getting on for 2 years now, pinned weekly. These days it's T15, still just the one jab a week.

 

[tcpnomad]

Two things are in tension when you pick a vial size:

1. How long one vial will last you. The usual guidance with gray, bac water or not, is to get through it inside a month.
   
2. How many vials you'll be reconstituting as you go. Fewer is better, but doing more is hardly a disaster — some folk actively enjoy it.

Below is a chart of dose against lifetime (in months) covering a range of Tirz and Reta doses. Might be handy.