Gf is asking about trying peptides — how do I handle it?

[oldrunnerguy]

lessthanhalf said:

desinr-gal said:

JohannesSweden77 said:

desinr-gal said:

JohannesSweden77 said:


So since I started taking tirz my girlfriend first didn't seem interested in taking it herself but now she's even getting a bit annoying pestering me that she wants to loose weight and try some peptides also. I don't know how to react really. I want to help her lose weight and feel better in her own body but at the same time I'm scared she'll have a bad reaction or something. I'm thinking about giving her a starter dose of tirz. That will most likely happen if she keeps nagging me. Don't know what my question is anymore but maybe someone have been in a situation like this?

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Begin at .25 so you can confirm she won't react badly and then hold you responsible. Increase the amount gradually after that. For me, .5 Tirz was enough to get a response, so there's no reason to burn through peptides when it isn't necessary.

For tirz that dose is far too small, though she did begin at the same starting dose prescribed to everyone on Mounjaro. Could you have meant 2,5mg?

SVT810E said:

Are people actually suggesting a dose that's just 1/10th of the standard starting amount? Might as well put them on homeopathic tirz while we're at it, just for extra caution. “The vendor's bac water remembers the tirz, plus a touch of norovirus. This stuff really works!”

For tirz, 2.5mg is a safe and effective dose to begin with.

Absolutely safe and effective. My own start wasn't as effective as hers, as far as I recall, but once I reached 5mg things picked up. I'm glad for her.

Nope, sweetie.

A 2.5 starting dose gives a lot of folks really rough side effects — nausea, stomach trouble, that sort of thing. My own start was .5, and I truly mean .5. Micro dosing was the approach we tried. It did work, by the way, and I moved up in tiny steps. After quite a few months I reached 2mg, and then I brought in Reta the same gradual way.

On either one, my ceiling stayed under 3mg, so under 6mg combined. I'm acquainted with people who topped out at 4mg of Tirze and still dropped every pound they were aiming for.

29% of my body weight came off.

that's my take

I'm not saying your results at those tiny doses aren't real, but only a fairly narrow slice of people will ever react that strongly to doses that low — super responders are probably just 5-10% of the population. Losing 29% of body weight from 6mg of reta / tirz is far above what the typical person sees.

There's a rationale behind the standard starting doses: they keep the chance of meaningful side effects reasonably low, while not stretching the ramp-up phase out by another 3-4 months. That's exactly how long it would take to reach 2.5mg if you began at 0.5 and increased by 0.5mg every 4 weeks. Under that approach, most people would burn the first 3, maybe even 6, months just getting to a dose that actually suppresses appetite and starts the weight loss — too long, in my view, and plenty would lose motivation when nothing happens. To me it's more reasonable to take on a few percent risk of an unpleasant side effect by starting at 2.5mg, rather than waiting months for any effect at all. At 2.5mg, side effects beyond mild nausea aren't very common, and if one does show up, you simply lower the dose.

Whether we're talking Reta or Tirz, my dose has stayed at or below 1.5mg the whole time. Call me a super responder if that fits — I'm not complaining one bit.

 

[Airborne Daddy]

bamagirl26 said:

At times I find myself asking whether compounding pharmacies operate the same way we do. For instance, what is the origin of the raw materials they use?

I honestly don't know, but my take is that they get 15-20kg of raws in and run tests on it before giving the green light. For comparison, a big underground steroid seller picks up 5kg in one order, and that's enough to keep producing for months.

 

[BNLFL]

Airborne Daddy said:

BNLFL said:

Airborne Daddy said:

boytres said:

Taking it yourself while not wanting her to research it on her own strikes me as a bit hypocritical. But thats just my opinion...

In my experience, the harder you push to stop someone doing what they want, the more certain it becomes that they will do it, and then some. Better to be supportive and enjoy the journey together. At least that way you know she's safe, and if anything goes wrong your there to help when she needs it.

At first my wife refused anything from China... until her sister mentioned dropping 56lbs thanks to the stuff I'd given her 12 months earlier.

Pretty much the same situation in our home. I let my wife know I'd be sourcing from a different place instead of the US vendor we'd been overpaying — 4 vials at crazy prices. She wanted to know where, and once I said China she flipped out. That lasted until I showed her that everything traces back to China, and that even the large companies, Lilly included, may well be getting raw materials from there. Once she heard about the testing, she calmed down. Everything's been fine since the weight started coming off and she felt no different.

I'm confident that vendors such as bff and nexaph undergo more testing than pharma does. When it comes to bff, stg runs tests on it roughly 12 times each month.

Straight up. That Google spreadsheet has plenty of BFF, and it stretches back to 2024.

 

[angeliquereta]

What makes you think your approval is required for her to do this?

 

[JohannesSweden77]

A few weeks in, and she's genuinely noticing a difference, including weight coming off. She told me earlier today that her constant hunger has faded and that alcohol doesn't really appeal to her anymore. All my reminders to drink plenty of water paid off — now she's just like me, carrying a big water bottle everywhere. Watching these shifts happen in another person rather than in myself is fascinating. Next week we'll find out whether her dose needs to go up or if she should remain at 2,5mg.

 

[Beansnapper]

JohannesSweden77 said:


So since I started taking tirz my girlfriend first didn't seem interested in taking it herself but now she's even getting a bit annoying pestering me that she wants to loose weight and try some peptides also. I don't know how to react really. I want to help her lose weight and feel better in her own body but at the same time I'm scared she'll have a bad reaction or something. I'm thinking about giving her a starter dose of tirz. That will most likely happen if she keeps nagging me. Don't know what my question is anymore but maybe someone have been in a situation like this?

Click to expand...

Quit acting like a gatekeeper and just get her started.

 

[JohannesSweden77]

Beansnapper said:

JohannesSweden77 said:


So since I started taking tirz my girlfriend first didn't seem interested in taking it herself but now she's even getting a bit annoying pestering me that she wants to loose weight and try some peptides also. I don't know how to react really. I want to help her lose weight and feel better in her own body but at the same time I'm scared she'll have a bad reaction or something. I'm thinking about giving her a starter dose of tirz. That will most likely happen if she keeps nagging me. Don't know what my question is anymore but maybe someone have been in a situation like this?

Click to expand...

Quit acting like a gatekeeper and just get her started.

Incredible. Have you considered going through the entire thread?

 

[JohannesSweden77]

Another quick update on how my girlfriend is doing on tirzepatide. One month in, and her weekly dose has moved up from 2,5mg to 5mg. She's feeling great, with no significant side effects. There are a few minor ones, such as spicy food being harder for her to eat (a shame, since she really loves spicy food). She mentioned that when she was out drinking with friends, she managed only half a glass and had no desire for more. So far she's down 5kg/11lb. She's started excersising and says her energy levels are much higher than they used to be. Overall, things are going very well indeed.

 

[boytres]

That's a really nice update!

I'm honestly glad for her — she's moving forward and working on improving her health.

Keep supporting each other; sharing the burden makes the path smoother!

 

[Kevin Jones]

Sharing your own supply with her is something I'd approach carefully. Since reactions vary from person to person, having a doctor involved beforehand looks like the wiser path. Still, I get why you'd want to support her!

 

[Isabella Rogers]

Handing over your own tirz is something I'd think twice about, particularly when she hasn't run it past a doctor yet. Supporting her matters, sure, but a bad reaction would leave you both regretting that you didn't go the safer way. Instead of feeling pushed into handing her a dose, perhaps guide her toward looking at the proper options.

 

[boytres]

Kevin Jones said:

Sharing your own supply with her is something I'd approach carefully. Since reactions vary from person to person, having a doctor involved beforehand looks like the wiser path. Still, I get why you'd want to support her!

Isabella Rogers said:

Handing over your own tirz is something I'd think twice about, particularly when she hasn't run it past a doctor yet. Supporting her matters, sure, but a bad reaction would leave you both regretting that you didn't go the safer way. Instead of feeling pushed into handing her a dose, perhaps guide her toward looking at the proper options.

I get why people are wary, but what else is there? If OP won't help, his partner will just go find her own Tirz from gray and use it regardless. To me, sharing the same source seems like it lowers the risk compared with two different sources.

Say one of them ends up with ISR, an infection, or something similar — they'd both stop, and that might spare the other person some harm.

They're two consenting adults who can each decide for themselves. I really don't think either one is being pushed so hard that they have to give in.

I already said this in an earlier post: if OP's partner decides she wants to start Tirz and OP won't give her access, she'll get it on her own, and that could end up hurting them both.

Once more, this is just how I see it, and I respect what both of you think too.

 

[BNLFL]

Kevin Jones said:

Sharing your own supply with her is something I'd approach carefully. Since reactions vary from person to person, having a doctor involved beforehand looks like the wiser path. Still, I get why you'd want to support her!

I don't mean to be rude, but that's not right. There's no chance I'm scheduling appointments for both of us over this. Who knows what the doctors would tell us, other than pushing something different from Reta. My wife and I have used the identical product at the identical dose, going up to 10mg, and next week we'll probably move to 12mg. I do the reconstitution, the filtering, and load the syringes on injection day, then shoot both her and myself.

Isabella Rogers said:

Handing over your own tirz is something I'd think twice about, particularly when she hasn't run it past a doctor yet. Supporting her matters, sure, but a bad reaction would leave you both regretting that you didn't go the safer way. Instead of feeling pushed into handing her a dose, perhaps guide her toward looking at the proper options.

Look at what I wrote above.

 

[Flash-BCR]

Kevin Jones said:

Sharing your own supply with her is something I'd approach carefully. Since reactions vary from person to person, having a doctor involved beforehand looks like the wiser path. Still, I get why you'd want to support her!

Isabella Rogers said:

Handing over your own tirz is something I'd think twice about, particularly when she hasn't run it past a doctor yet. Supporting her matters, sure, but a bad reaction would leave you both regretting that you didn't go the safer way. Instead of feeling pushed into handing her a dose, perhaps guide her toward looking at the proper options.

What would a doctor actually say to her?..."you don't meet the weight criteria for GLPs yet"?..."here's a prescription for Zepbound/Mounjaro" $$$$?..."diet and exercise should be your first approach to losing weight"?