Stormblessed91 said:
I'm looking for advice before I begin — what should I do and what should I avoid? A number of posts I've come across mention dosing either just before sleep or right after waking up. Only once daily, so I'm curious whether one timing is recommended over the other, or if either is equally effective.
I don't know how old you are, and that matters because in my honest opinion this primarily helps people who are 45 or older — or someone going through puberty who wants more gh, say to grow taller.
I'm 60 and my gh is very low because of aghd — and yes, it did make a difference for me, though not a dramatic one. I stayed on it for 5 wks, then became sensitized to it and moved to 191aa.
So, assuming you have a standard 5+5 vial: add 3ml bac h20 to the 5+5 vial. The resulting solution, when you draw 12 units on an insulin syringe, delivers .2mcg of cjc/ipam. The suggested dose for this is 150-200 mcg — taking more doesn't help.
Roughly 2-5 minutes after you take it, a mild flush will come over your face — that's how you'll know it's active.
My recommendation is to use it right before bed. Your pituitary releases gh while you sleep, and cjc/ipam has a half life of about 2 hr, so it supports your pituitary in putting out maximum gh overnight. Yes, it works — and it works best when you're older. When you're younger your pituitary already functions well, so the response is smaller. You notice the extra gh when you're older and your pituitary isn't putting out much gh.
It does work — but it's not as effective as 191aa (hgh).
A few pointers:
Don't use cjc while you're on high doses of 191aa, 5+iu.
If you're using low doses of hgh first thing in the morning, you can still use cjc at night. The reason: hgh raises your igf1 blood markers a lot, and those markers are what signal your pituitary to stop releasing gh — they take 12-15 hours to fall. For cjc/ipam to work well, you want those igf1 blood markers low.
Also, a large meal triggers an insulin spike, which in turn causes a big rise in igf1 — again signaling your pituitary not to release gh. That's why people who eat a lot right before bed end up robbing themselves of extra gh. Your pituitary releases gh best when you're fasted.
That's the reasoning behind taking it right before bed — ideally about 3-4+ hours after your last meal.
Also, if you do heavy cardio or weight training, you can take cjc/ipam — or cjc alone — right before the cardio or the weights. Your pituitary puts out more gh during intense weightlifting and intense cardio, and one of the best ways to boost that output is sprinting — yes, seriously, sprinting.
You can also take it first thing in the morning if you prefer (while fasted), then do cardio or weightlifting — that's what most people do — and again it will raise your pituitary gh output during that window.
The gap between cjc/ipam and hgh is night and day. That said, hgh carries more side effects and is used for different reasons. It won't give you huge muscles or make you 21 again, though if you're an older guy or gal it will make you feel 20 yrs younger — it changes your body for the better, really for the better. At low doses, hgh has very few side effects.
Again — just keep in mind that a fasted state is best for cjc/ipam.
Finally — remember you will become sensitized to this, so do 3-4 weeks on, then a few weeks off. Ymmv.
Good luck — I hope you get some benefit from it. It's where I started.