Considering stacking cagri with reta — would that help my food noise?

BailyHaywood

BailyHaywood

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I take 1mg of reta every other day, since that schedule has given me the most consistent effects. My deficit isn't very aggressive — roughly 400-600 a day — and occasionally I go over it, or on days when I'm not feeling it I just eat at maintenance. The problem is the food noise is still terrible, and I've read a lot of positive reports about cagri helping with that. Would you recommend it in my case, or do you think I should try a different approach for now?
 
My current stack is 7mg (working my way down to 5mg) of Tirz together with 5mg Reta and 1mg Cagri. Back when I was on 15mg Tirz, the food noise stayed manageable. Once I began tapering down so I could bring Reta in, that food noise returned. With all 3 in the mix now, it's manageable once more.
 
Cagri pulled me out of a plateau in just a couple of weeks. Just keep an eye on how you dose it and how often you take it.
 
Silver said:

Cagri pulled me out of a plateau in just a couple of weeks. Just keep an eye on how you dose it and how often you take it.
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Yeah, I've come across those horror stories😂 but I appreciate the warnings. My plan is to begin at 150mcg once a week and then see how things go from that point👍
 
BailyHaywood said:

Yeah, I've come across those horror stories😂 but I appreciate the warnings. My plan is to begin at 150mcg once a week and then see how things go from that point👍
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My starting dose was .25mg (250mcg). After a week at that level I went up to .5mg and stayed there for 2 weeks. Next came .75mg for a week, and this past week I've been at 1mg.
 
Milo said:

What would you recommend instead for keeping food noise in check?
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When it comes to keeping food noise under control, tirzepatide is the stronger option. The likely reason is that its GIP activity packs more of a punch.

From a structural standpoint, tirzepatide behaves as an "imbalanced" agonist — it leans toward engaging the GIP receptor rather than the GLP-1 receptor.

On the other hand, if your goal is the biggest weight loss numbers, retatrutide is the one that delivers that. The catch is that food noise tends to stay a problem for a larger share of people using retatrutide.
 
Just A Cat said:

When it comes to keeping food noise under control, tirzepatide is the stronger option. The likely reason is that its GIP activity packs more of a punch.

From a structural standpoint, tirzepatide behaves as an "imbalanced" agonist — it leans toward engaging the GIP receptor rather than the GLP-1 receptor.

On the other hand, if your goal is the biggest weight loss numbers, retatrutide is the one that delivers that. The catch is that food noise tends to stay a problem for a larger share of people using retatrutide.
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After switching over completely from tirz to reta, the food noise came back a lot stronger — honestly, it caught me off guard. I've got some cagri sitting here, but I haven't given it a try yet. My plan is to pick up 20mg tirz vials and stack those with the reta. I'm on 5mg reta, and I'd begin the tirz at 2.5mg, then titrate upward, possibly reaching 4mg.

As for cagri... I've come across reports of bad reactions. I do want to test it out, but the vials I have are 10mg, and I'm worried about two things: how long it stays good after reconstitution, and how my body would handle it.
 
tekkit said:

After switching over completely from tirz to reta, the food noise came back a lot stronger — honestly, it caught me off guard. I've got some cagri sitting here, but I haven't given it a try yet. My plan is to pick up 20mg tirz vials and stack those with the reta. I'm on 5mg reta, and I'd begin the tirz at 2.5mg, then titrate upward, possibly reaching 4mg.

As for cagri... I've come across reports of bad reactions. I do want to test it out, but the vials I have are 10mg, and I'm worried about two things: how long it stays good after reconstitution, and how my body would handle it.
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For me, cagri has worked incredibly well. Ease into it very gradually. I did get 2 days where I felt wiped out, but given how Reta pushes your heart rate up and wrecks your sleep, that tiredness can actually be a welcome bonus at times haha. The fatigue stuck around for just those 2 days
 
Clavicular's Hammer said:

For me, cagri has worked incredibly well. Ease into it very gradually. I did get 2 days where I felt wiped out, but given how Reta pushes your heart rate up and wrecks your sleep, that tiredness can actually be a welcome bonus at times haha. The fatigue stuck around for just those 2 days
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What was your starting dose, and how long do you feel okay leaving it mixed up? I was after 5mg vials, but stock problems left me with 10mg instead. Back then I had no idea cagri doses could go that low.
 
tekkit said:

What was your starting dose, and how long do you feel okay leaving it mixed up? I was after 5mg vials, but stock problems left me with 10mg instead. Back then I had no idea cagri doses could go that low.
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My first day was about .05mg, then .1 the following day, and slightly more than that on day three.

After that came two days of fatigue.

Since then I've been dosing closer to .3mg, spaced out every 3-4 days.

My vials are 5mg, and I'm hoping to stretch them across roughly 45 days.

Appetite is gone, and the sides have been minimal.
 
Clavicular's Hammer said:

My first day was about .05mg, then .1 the following day, and slightly more than that on day three.

After that came two days of fatigue.

Since then I've been dosing closer to .3mg, spaced out every 3-4 days.

My vials are 5mg, and I'm hoping to stretch them across roughly 45 days.

Appetite is gone, and the sides have been minimal.
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I really appreciate you taking the time to share this!
 
I've had a few months on Cagri now. Looking back, I let the chatter about side effects shape my titration schedule more than it should have. Aside from some mild constipation, I've had zero sides on Reta, Tirz, or Cagri.

Right now my weekly Cagri dose is 1.25mg, stacked with 7.5mg Tirz and 4mg Reta. A few hours after injecting, I can feel the Cagri, but that fades within a few days. That's okay, since my schedule never leaves me far from the next GLP shot.

I'm 1 or 2 pounds from my first goal weight and now chasing a second one. My reason for trying Cagri was to learn how the peptide behaves. Were I to start it over, I'd titrate harder. For me, the sweet spot would land somewhere between 2mg and 3mg. No two people are alike, and my experience is just a data point.

Not long ago someone here pointed out how American it is to tinker with something that already works perfectly well. I got a kick out of that spot on remark. I have a few kits of Uther Elora headed my way, which I want to test as a replacement for my Cagri. Down the road, I'm sure improved versions of Tirz and Reta will show up, and I'll tinker with those too.

Zippy gets cranky around links, but Dr. Kevin Joseph just put out a fresh video that discusses the difference between Cagri and Elora really well. It's worth tracking down.
 
Seasonal1 said:

I've had a few months on Cagri now. Looking back, I let the chatter about side effects shape my titration schedule more than it should have. Aside from some mild constipation, I've had zero sides on Reta, Tirz, or Cagri.

Right now my weekly Cagri dose is 1.25mg, stacked with 7.5mg Tirz and 4mg Reta. A few hours after injecting, I can feel the Cagri, but that fades within a few days. That's okay, since my schedule never leaves me far from the next GLP shot.

I'm 1 or 2 pounds from my first goal weight and now chasing a second one. My reason for trying Cagri was to learn how the peptide behaves. Were I to start it over, I'd titrate harder. For me, the sweet spot would land somewhere between 2mg and 3mg. No two people are alike, and my experience is just a data point.

Not long ago someone here pointed out how American it is to tinker with something that already works perfectly well. I got a kick out of that spot on remark. I have a few kits of Uther Elora headed my way, which I want to test as a replacement for my Cagri. Down the road, I'm sure improved versions of Tirz and Reta will show up, and I'll tinker with those too.

Zippy gets cranky around links, but Dr. Kevin Joseph just put out a fresh video that discusses the difference between Cagri and Elora really well. It's worth tracking down.
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Normally I skip videos, but for anyone wanting a basic introduction to eloralintide, this one was worth it.
 
For me, cagri has been a 100% help. My RETA dose lands on Monday at 4mg. Then on Tuesday I add Cagri, up to 1mg, and how much depends on the noise. It genuinely works in my case. My suggestion: buy a single vial, even at the premium price, and test it out — look over your COA and begin low, around .25 mg for a week or two, then move to .50mg. By the way, .50mg kept working for me for months. Whether it affects women differently than men, I can't say — but that's exactly what this sandbox is here for — try it out before you buy a whole kit. 😁
 
Seasonal1 said:

I've had a few months on Cagri now. Looking back, I let the chatter about side effects shape my titration schedule more than it should have. Aside from some mild constipation, I've had zero sides on Reta, Tirz, or Cagri.

Right now my weekly Cagri dose is 1.25mg, stacked with 7.5mg Tirz and 4mg Reta. A few hours after injecting, I can feel the Cagri, but that fades within a few days. That's okay, since my schedule never leaves me far from the next GLP shot.

I'm 1 or 2 pounds from my first goal weight and now chasing a second one. My reason for trying Cagri was to learn how the peptide behaves. Were I to start it over, I'd titrate harder. For me, the sweet spot would land somewhere between 2mg and 3mg. No two people are alike, and my experience is just a data point.

Not long ago someone here pointed out how American it is to tinker with something that already works perfectly well. I got a kick out of that spot on remark. I have a few kits of Uther Elora headed my way, which I want to test as a replacement for my Cagri. Down the road, I'm sure improved versions of Tirz and Reta will show up, and I'll tinker with those too.

Zippy gets cranky around links, but Dr. Kevin Joseph just put out a fresh video that discusses the difference between Cagri and Elora really well. It's worth tracking down.
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LOL.

Adding a dozen extra parts to an engine that already runs perfectly, just so it becomes harder to diagnose and repair — that is so German.
 
Cagri never did anything for me. I picked up 4 single vials, gave it 2 tries, and there are 2 vials still sitting around.

My weight has been stuck at 160 for quite a while. I just had blood tests done for insurance, and I still fall into the "over weight" category. That doesn't really bother me, but it has gotten me interested again in breaking out of this stall. I've now got a couple of screenshots of doses I could try — love this place.
 
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