Anyone who does not store in the fridge?
- Thread starter Gohengrin
- Start date
Came across this on the internet.. ((Compounded pharma versions — For semaglutide/tirzepatide (like compounded versions of Ozempic/Mounjaro/Zepbound), official labeling often allows up to 21–30 days at room temperature (below ~86°F/30°C) after first use or reconstitution, so people follow that and skip the fridge entirely for the in-use period.))
Hoping this is useful? I'm sure others with more knowledge will chime in.
Hoping this is useful? I'm sure others with more knowledge will chime in.
cygnus
Explorer
My approach was the opposite: I bought a small separate fridge just for peptides, and it has a tiny freezer compartment so I can keep things for longer periods.
390120
Explorer
Did it still work?
In theory, it will break down quickly and lose potency, so even if you don’t feel any negative effects, it may have had no effect once injected into your body. I wouldn’t take that chance and would just refrigerate it regardless
In theory, it will break down quickly and lose potency, so even if you don’t feel any negative effects, it may have had no effect once injected into your body. I wouldn’t take that chance and would just refrigerate it regardless
Another thing worth checking out is a buzzer or alarm that goes off when the temperature falls. Years back I picked one up for my deep freezer, and when something goes wrong it alerts me. I'd bet they don't cost much, and they give you peace of mind, right?
As @DjJoshua mentioned, Big Pharma permits a stretch at room temperature. Whether that applies to multi-dose injectors sold in certain markets, I'm not sure.
IMO contamination worries me more than degradation. My guess is that sterility holds up for a couple of weeks at room temp—think fridge breakdowns or days spent traveling—if you're using bacteriostatic water and sanitizing surfaces properly with alcohol swabs. Still, keeping it cold is the better option.
IMO contamination worries me more than degradation. My guess is that sterility holds up for a couple of weeks at room temp—think fridge breakdowns or days spent traveling—if you're using bacteriostatic water and sanitizing surfaces properly with alcohol swabs. Still, keeping it cold is the better option.
woundcarping
Explorer
"Rapidly degrade" depends on the situation.
Cold storage cuts down oxidation a lot, and hydrolysis too, so the peptide stays intact for a longer period. Based on what I've come across, putting it in the fridge may reduce degradation by roughly 4x versus leaving it at room temperature (the exact figure varies by compound and by the process).
Compared with refrigerated vials, those containing BAC show greater bacterial and fungal activity when kept at room temp... BAC gives you more time. Reusing a vial multiple times can become a possible route for additional contamination.
I have personally used peptides that were not refrigerated (around 65* temps) in multi use vials. For me, the acceptable limit for a non refrigerated vial is roughly 2 weeks, if we assume standard "room temperature".
Cold storage cuts down oxidation a lot, and hydrolysis too, so the peptide stays intact for a longer period. Based on what I've come across, putting it in the fridge may reduce degradation by roughly 4x versus leaving it at room temperature (the exact figure varies by compound and by the process).
Compared with refrigerated vials, those containing BAC show greater bacterial and fungal activity when kept at room temp... BAC gives you more time. Reusing a vial multiple times can become a possible route for additional contamination.
I have personally used peptides that were not refrigerated (around 65* temps) in multi use vials. For me, the acceptable limit for a non refrigerated vial is roughly 2 weeks, if we assume standard "room temperature".