AFIB Episode While on Retatrutide

[cujet]

62M, used to be an athlete. Weight now holds around 192 pounds (roughly where I want to be), previously 262. Still strong and able to go slow for long stretches, even with several autoimmune conditions. Those conditions triggered AFIB 30 years back. Nothing since then, until this happened.

I was up on my moving truck and tumbled out of the cab, roughly 6 feet to the ground. I had been putting together a platform for my puppy, stepped off it, and missed the foothold. My headphones smashed against a nearby tree (that's what kept me from getting hurt), then I struck the truck, then landed. I ended up battered and scraped. The series of impacts is what stopped any bones from breaking, since each one slowed the fall.

Right away my pulse jumped to 160 and would not come down. I stayed on the ground for 30 minutes hoping it would calm. My Apple watch flagged AFIB along with a high rate that was gradually dropping. The next night, a little over 24 hours afterward, I went back into a steady sinus rhythm during a good hot shower, with a pleasant Ahhhh sensation, and nothing since.

No doubt the adrenaline from the fall drove my heart rate up.

Because I had gone 30 years without AFIB (that earlier case came from a heart infection), even after plenty of dirt bike wrecks, SeaDoo wave jumping and racing chaos, and bicycle racing crashes with fractures, I believe Retatrutide tipped me past the limit. I had just increased to 5mg/wk, which appears to be my maintenance dose. On Reta my resting heart rate is probably above my fit-normal, though I can't say by how much. It was also elevated when my weight was higher. Perhaps 82bpm either way. Fat, or on Reta.

 

[QueenMuntha]

Reta seems to set off AFib episodes even at .5mg per week, triggered by minor things such as eating tomato sauce or having food within 6 hours of going to bed. None of this occurred prior to when I reintroduced small Reta doses, after having quit it because of back pain tied to the gall bladder.

I'm not claiming correlation equals causation, but it is mighty peculiar. This is my 5am Kardia reading on Wed, following spaghetti and meatballs with tomato sauce at 5pm. (200 mg of Flecainide settled it after 2 hours.)

 

[JCO79]

AF tends to occur more often when the body is in a high adrenergic state. Given that this person is 62 and had likely been carrying excess weight for many years, there is no way to determine whether this episode would have brought on AF even without Reta. Still, this could be a rationale for switching to Tirz. Tirz simply appears not to produce the same rise in sympathetic tone that Reta does.

 

[SeaGypsy]

At a 2.5mg low dose of Reta, I ran into heart rate problems. Even while just sitting around watching television, my readings would occasionally jump into the 130s and 140s. After switching back to Tirz, everything returned to normal.

 

[birdwhacker]

cujet said:

62M, used to be an athlete. Weight now holds around 192 pounds (roughly where I want to be), previously 262. Still strong and able to go slow for long stretches, even with several autoimmune conditions. Those conditions triggered AFIB 30 years back. Nothing since then, until this happened.

I was up on my moving truck and tumbled out of the cab, roughly 6 feet to the ground. I had been putting together a platform for my puppy, stepped off it, and missed the foothold. My headphones smashed against a nearby tree (that's what kept me from getting hurt), then I struck the truck, then landed. I ended up battered and scraped. The series of impacts is what stopped any bones from breaking, since each one slowed the fall.

Right away my pulse jumped to 160 and would not come down. I stayed on the ground for 30 minutes hoping it would calm. My Apple watch flagged AFIB along with a high rate that was gradually dropping. The next night, a little over 24 hours afterward, I went back into a steady sinus rhythm during a good hot shower, with a pleasant Ahhhh sensation, and nothing since.

No doubt the adrenaline from the fall drove my heart rate up.

Because I had gone 30 years without AFIB (that earlier case came from a heart infection), even after plenty of dirt bike wrecks, SeaDoo wave jumping and racing chaos, and bicycle racing crashes with fractures, I believe Retatrutide tipped me past the limit. I had just increased to 5mg/wk, which appears to be my maintenance dose. On Reta my resting heart rate is probably above my fit-normal, though I can't say by how much. It was also elevated when my weight was higher. Perhaps 82bpm either way. Fat, or on Reta.

QueenMuntha said:

Reta seems to set off AFib episodes even at .5mg per week, triggered by minor things such as eating tomato sauce or having food within 6 hours of going to bed. None of this occurred prior to when I reintroduced small Reta doses, after having quit it because of back pain tied to the gall bladder.

I'm not claiming correlation equals causation, but it is mighty peculiar. This is my 5am Kardia reading on Wed, following spaghetti and meatballs with tomato sauce at 5pm. (200 mg of Flecainide settled it after 2 hours.)

SeaGypsy said:

At a 2.5mg low dose of Reta, I ran into heart rate problems. Even while just sitting around watching television, my readings would occasionally jump into the 130s and 140s. After switching back to Tirz, everything returned to normal.

I have a question for each of you:

Are magnesium and potassium part of your daily routine? Which supplements are you on, and is there anything you take specifically to support heart health?

 

[QueenMuntha]

birdwhacker said:

cujet said:

62M, used to be an athlete. Weight now holds around 192 pounds (roughly where I want to be), previously 262. Still strong and able to go slow for long stretches, even with several autoimmune conditions. Those conditions triggered AFIB 30 years back. Nothing since then, until this happened.

I was up on my moving truck and tumbled out of the cab, roughly 6 feet to the ground. I had been putting together a platform for my puppy, stepped off it, and missed the foothold. My headphones smashed against a nearby tree (that's what kept me from getting hurt), then I struck the truck, then landed. I ended up battered and scraped. The series of impacts is what stopped any bones from breaking, since each one slowed the fall.

Right away my pulse jumped to 160 and would not come down. I stayed on the ground for 30 minutes hoping it would calm. My Apple watch flagged AFIB along with a high rate that was gradually dropping. The next night, a little over 24 hours afterward, I went back into a steady sinus rhythm during a good hot shower, with a pleasant Ahhhh sensation, and nothing since.

No doubt the adrenaline from the fall drove my heart rate up.

Because I had gone 30 years without AFIB (that earlier case came from a heart infection), even after plenty of dirt bike wrecks, SeaDoo wave jumping and racing chaos, and bicycle racing crashes with fractures, I believe Retatrutide tipped me past the limit. I had just increased to 5mg/wk, which appears to be my maintenance dose. On Reta my resting heart rate is probably above my fit-normal, though I can't say by how much. It was also elevated when my weight was higher. Perhaps 82bpm either way. Fat, or on Reta.

QueenMuntha said:

Reta seems to set off AFib episodes even at .5mg per week, triggered by minor things such as eating tomato sauce or having food within 6 hours of going to bed. None of this occurred prior to when I reintroduced small Reta doses, after having quit it because of back pain tied to the gall bladder.

I'm not claiming correlation equals causation, but it is mighty peculiar. This is my 5am Kardia reading on Wed, following spaghetti and meatballs with tomato sauce at 5pm. (200 mg of Flecainide settled it after 2 hours.)

SeaGypsy said:

At a 2.5mg low dose of Reta, I ran into heart rate problems. Even while just sitting around watching television, my readings would occasionally jump into the 130s and 140s. After switching back to Tirz, everything returned to normal.

I have a question for each of you:

Are magnesium and potassium part of your daily routine? Which supplements are you on, and is there anything you take specifically to support heart health?

Nope, I don't take any supplements. My regimen is just 75mg Metoprolol, 50 mg Flecainide bid and Xarelto.

Magnesium didn't do anything for me when I gave it a shot. That said, prior to starting Reta, my AFib episodes were only around 3 times/year. Oh, and I can't forget my trusty CPAP.

 

[birdwhacker]

QueenMuntha said:

birdwhacker said:

cujet said:

62M, used to be an athlete. Weight now holds around 192 pounds (roughly where I want to be), previously 262. Still strong and able to go slow for long stretches, even with several autoimmune conditions. Those conditions triggered AFIB 30 years back. Nothing since then, until this happened.

I was up on my moving truck and tumbled out of the cab, roughly 6 feet to the ground. I had been putting together a platform for my puppy, stepped off it, and missed the foothold. My headphones smashed against a nearby tree (that's what kept me from getting hurt), then I struck the truck, then landed. I ended up battered and scraped. The series of impacts is what stopped any bones from breaking, since each one slowed the fall.

Right away my pulse jumped to 160 and would not come down. I stayed on the ground for 30 minutes hoping it would calm. My Apple watch flagged AFIB along with a high rate that was gradually dropping. The next night, a little over 24 hours afterward, I went back into a steady sinus rhythm during a good hot shower, with a pleasant Ahhhh sensation, and nothing since.

No doubt the adrenaline from the fall drove my heart rate up.

Because I had gone 30 years without AFIB (that earlier case came from a heart infection), even after plenty of dirt bike wrecks, SeaDoo wave jumping and racing chaos, and bicycle racing crashes with fractures, I believe Retatrutide tipped me past the limit. I had just increased to 5mg/wk, which appears to be my maintenance dose. On Reta my resting heart rate is probably above my fit-normal, though I can't say by how much. It was also elevated when my weight was higher. Perhaps 82bpm either way. Fat, or on Reta.

QueenMuntha said:

Reta seems to set off AFib episodes even at .5mg per week, triggered by minor things such as eating tomato sauce or having food within 6 hours of going to bed. None of this occurred prior to when I reintroduced small Reta doses, after having quit it because of back pain tied to the gall bladder.

I'm not claiming correlation equals causation, but it is mighty peculiar. This is my 5am Kardia reading on Wed, following spaghetti and meatballs with tomato sauce at 5pm. (200 mg of Flecainide settled it after 2 hours.)

SeaGypsy said:

At a 2.5mg low dose of Reta, I ran into heart rate problems. Even while just sitting around watching television, my readings would occasionally jump into the 130s and 140s. After switching back to Tirz, everything returned to normal.

I have a question for each of you:

Are magnesium and potassium part of your daily routine? Which supplements are you on, and is there anything you take specifically to support heart health?

Nope, I don't take any supplements. My regimen is just 75mg Metoprolol, 50 mg Flecainide bid and Xarelto.

Magnesium didn't do anything for me when I gave it a shot. That said, prior to starting Reta, my AFib episodes were only around 3 times/year. Oh, and I can't forget my trusty CPAP.

That's rough. At the very least, if nothing else, I'd strongly urge you to start taking 200mg of elemental magnesium daily in the form of magnesium glycinate. Both Doctor's Best and Now Foods are solid choices.

QueenMuntha said:

birdwhacker said:

cujet said:

62M, used to be an athlete. Weight now holds around 192 pounds (roughly where I want to be), previously 262. Still strong and able to go slow for long stretches, even with several autoimmune conditions. Those conditions triggered AFIB 30 years back. Nothing since then, until this happened.

I was up on my moving truck and tumbled out of the cab, roughly 6 feet to the ground. I had been putting together a platform for my puppy, stepped off it, and missed the foothold. My headphones smashed against a nearby tree (that's what kept me from getting hurt), then I struck the truck, then landed. I ended up battered and scraped. The series of impacts is what stopped any bones from breaking, since each one slowed the fall.

Right away my pulse jumped to 160 and would not come down. I stayed on the ground for 30 minutes hoping it would calm. My Apple watch flagged AFIB along with a high rate that was gradually dropping. The next night, a little over 24 hours afterward, I went back into a steady sinus rhythm during a good hot shower, with a pleasant Ahhhh sensation, and nothing since.

No doubt the adrenaline from the fall drove my heart rate up.

Because I had gone 30 years without AFIB (that earlier case came from a heart infection), even after plenty of dirt bike wrecks, SeaDoo wave jumping and racing chaos, and bicycle racing crashes with fractures, I believe Retatrutide tipped me past the limit. I had just increased to 5mg/wk, which appears to be my maintenance dose. On Reta my resting heart rate is probably above my fit-normal, though I can't say by how much. It was also elevated when my weight was higher. Perhaps 82bpm either way. Fat, or on Reta.

QueenMuntha said:

Reta seems to set off AFib episodes even at .5mg per week, triggered by minor things such as eating tomato sauce or having food within 6 hours of going to bed. None of this occurred prior to when I reintroduced small Reta doses, after having quit it because of back pain tied to the gall bladder.

I'm not claiming correlation equals causation, but it is mighty peculiar. This is my 5am Kardia reading on Wed, following spaghetti and meatballs with tomato sauce at 5pm. (200 mg of Flecainide settled it after 2 hours.)

SeaGypsy said:

At a 2.5mg low dose of Reta, I ran into heart rate problems. Even while just sitting around watching television, my readings would occasionally jump into the 130s and 140s. After switching back to Tirz, everything returned to normal.

I have a question for each of you:

Are magnesium and potassium part of your daily routine? Which supplements are you on, and is there anything you take specifically to support heart health?

Nope, I don't take any supplements. My regimen is just 75mg Metoprolol, 50 mg Flecainide bid and Xarelto.

Magnesium didn't do anything for me when I gave it a shot. That said, prior to starting Reta, my AFib episodes were only around 3 times/year. Oh, and I can't forget my trusty CPAP.

Xarelto—ha, that brings back memories. I ended up with an embolism after the covid vaccine a few years ago. My mom had to grab a sample for me from one of her offices since the doctor I saw afterward refused to prescribe it, doubting my account. Good times. I was on it for 3 months, plus a ton of NAC, natto, fish oil, iodine, vitamin D, and zinc.

If you're on a blood thinner, adding omega 3 is wise too. Now Foods Liquid is the most budget-friendly, but if you're feeling fancy, go for Nordic Naturals.

QueenMuntha said:

birdwhacker said:

cujet said:

62M, used to be an athlete. Weight now holds around 192 pounds (roughly where I want to be), previously 262. Still strong and able to go slow for long stretches, even with several autoimmune conditions. Those conditions triggered AFIB 30 years back. Nothing since then, until this happened.

I was up on my moving truck and tumbled out of the cab, roughly 6 feet to the ground. I had been putting together a platform for my puppy, stepped off it, and missed the foothold. My headphones smashed against a nearby tree (that's what kept me from getting hurt), then I struck the truck, then landed. I ended up battered and scraped. The series of impacts is what stopped any bones from breaking, since each one slowed the fall.

Right away my pulse jumped to 160 and would not come down. I stayed on the ground for 30 minutes hoping it would calm. My Apple watch flagged AFIB along with a high rate that was gradually dropping. The next night, a little over 24 hours afterward, I went back into a steady sinus rhythm during a good hot shower, with a pleasant Ahhhh sensation, and nothing since.

No doubt the adrenaline from the fall drove my heart rate up.

Because I had gone 30 years without AFIB (that earlier case came from a heart infection), even after plenty of dirt bike wrecks, SeaDoo wave jumping and racing chaos, and bicycle racing crashes with fractures, I believe Retatrutide tipped me past the limit. I had just increased to 5mg/wk, which appears to be my maintenance dose. On Reta my resting heart rate is probably above my fit-normal, though I can't say by how much. It was also elevated when my weight was higher. Perhaps 82bpm either way. Fat, or on Reta.

QueenMuntha said:

Reta seems to set off AFib episodes even at .5mg per week, triggered by minor things such as eating tomato sauce or having food within 6 hours of going to bed. None of this occurred prior to when I reintroduced small Reta doses, after having quit it because of back pain tied to the gall bladder.

I'm not claiming correlation equals causation, but it is mighty peculiar. This is my 5am Kardia reading on Wed, following spaghetti and meatballs with tomato sauce at 5pm. (200 mg of Flecainide settled it after 2 hours.)

SeaGypsy said:

At a 2.5mg low dose of Reta, I ran into heart rate problems. Even while just sitting around watching television, my readings would occasionally jump into the 130s and 140s. After switching back to Tirz, everything returned to normal.

I have a question for each of you:

Are magnesium and potassium part of your daily routine? Which supplements are you on, and is there anything you take specifically to support heart health?

Nope, I don't take any supplements. My regimen is just 75mg Metoprolol, 50 mg Flecainide bid and Xarelto.

Magnesium didn't do anything for me when I gave it a shot. That said, prior to starting Reta, my AFib episodes were only around 3 times/year. Oh, and I can't forget my trusty CPAP.

There are times I don't notice a change after brushing my teeth, but you still need to do it at least a few times a week. That's just basic self-care. Skipping all supplements seems insane to me.

 

[lessthanhalf]

It seems like this situation calls for a cardiologist's assessment, along with making them aware of the reta. Based on what I've read here about reta raising heart rates and triggering some panic attacks, I was honestly surprised that nobody had reported an arrhythmia yet—it stands to reason they'd become more likely, since sympathetic nervous system activity and heart rate both go up.

Maybe you already did this, but nothing in what you wrote indicates you got medical care.

With AF, a rate of 160 is high enough to be problematic: it's too fast for the heart to pump efficiently and could bring on heart failure, and I don't believe it's safe to let it stay that elevated for long without expert guidance. I can't see any reason why the right move here wouldn't be to head straight to an emergency department, particularly since this isn't something that has occurred many times before and has been handled by a specialist.

In the past, treating AF focused on achieving rate control to manage the problem, but these days far more emphasis is placed on restoring sinus rhythm when that's possible, because AF can produce left atrial clots that may dislodge and cause strokes. Both transitioning in and out of AF and remaining in AF over the long term can bring that about. That in turn means anticoagulant drugs are needed to prevent strokes.

I haven't come across substantial research on reta and heart disease, but judging only from what's been shared on this forum, for people with established heart disease—and arrhythmias in particular—there's a solid case for picking tirz instead. And even 1 episode of AF calls for an expert's opinion on how to manage it.

 

[SeaGypsy]

birdwhacker said:

cujet said:

62M, used to be an athlete. Weight now holds around 192 pounds (roughly where I want to be), previously 262. Still strong and able to go slow for long stretches, even with several autoimmune conditions. Those conditions triggered AFIB 30 years back. Nothing since then, until this happened.

I was up on my moving truck and tumbled out of the cab, roughly 6 feet to the ground. I had been putting together a platform for my puppy, stepped off it, and missed the foothold. My headphones smashed against a nearby tree (that's what kept me from getting hurt), then I struck the truck, then landed. I ended up battered and scraped. The series of impacts is what stopped any bones from breaking, since each one slowed the fall.

Right away my pulse jumped to 160 and would not come down. I stayed on the ground for 30 minutes hoping it would calm. My Apple watch flagged AFIB along with a high rate that was gradually dropping. The next night, a little over 24 hours afterward, I went back into a steady sinus rhythm during a good hot shower, with a pleasant Ahhhh sensation, and nothing since.

No doubt the adrenaline from the fall drove my heart rate up.

Because I had gone 30 years without AFIB (that earlier case came from a heart infection), even after plenty of dirt bike wrecks, SeaDoo wave jumping and racing chaos, and bicycle racing crashes with fractures, I believe Retatrutide tipped me past the limit. I had just increased to 5mg/wk, which appears to be my maintenance dose. On Reta my resting heart rate is probably above my fit-normal, though I can't say by how much. It was also elevated when my weight was higher. Perhaps 82bpm either way. Fat, or on Reta.

QueenMuntha said:

Reta seems to set off AFib episodes even at .5mg per week, triggered by minor things such as eating tomato sauce or having food within 6 hours of going to bed. None of this occurred prior to when I reintroduced small Reta doses, after having quit it because of back pain tied to the gall bladder.

I'm not claiming correlation equals causation, but it is mighty peculiar. This is my 5am Kardia reading on Wed, following spaghetti and meatballs with tomato sauce at 5pm. (200 mg of Flecainide settled it after 2 hours.)

SeaGypsy said:

At a 2.5mg low dose of Reta, I ran into heart rate problems. Even while just sitting around watching television, my readings would occasionally jump into the 130s and 140s. After switching back to Tirz, everything returned to normal.

I have a question for each of you:

Are magnesium and potassium part of your daily routine? Which supplements are you on, and is there anything you take specifically to support heart health?

Other than a daily multivitamin, I take nothing extra. My whole life, both my blood pressure and heart rate ran on the low side...that is, until Reta came along. From this point forward, I'm sticking with Tirz. Nothing heart-related has ever been prescribed to me.

 

[JCO79]

TRIUMPH-3, which is 1 of the phase 3 trials for Reta, is focused on how Reta affects individuals who already have cardiovascular disease. Eli Lilly would not put money behind that kind of study unless there were signs it would help. That said, it likely won't suit everyone. My guess is that a notable number of atrial fibrillation cases will show up, even if the overall effect is a lower AF risk. Tirz appears to avoid this issue and has demonstrated a positive impact on AF burden.

 

[QueenMuntha]

birdwhacker said:

QueenMuntha said:

birdwhacker said:

cujet said:

62M, used to be an athlete. Weight now holds around 192 pounds (roughly where I want to be), previously 262. Still strong and able to go slow for long stretches, even with several autoimmune conditions. Those conditions triggered AFIB 30 years back. Nothing since then, until this happened.

I was up on my moving truck and tumbled out of the cab, roughly 6 feet to the ground. I had been putting together a platform for my puppy, stepped off it, and missed the foothold. My headphones smashed against a nearby tree (that's what kept me from getting hurt), then I struck the truck, then landed. I ended up battered and scraped. The series of impacts is what stopped any bones from breaking, since each one slowed the fall.

Right away my pulse jumped to 160 and would not come down. I stayed on the ground for 30 minutes hoping it would calm. My Apple watch flagged AFIB along with a high rate that was gradually dropping. The next night, a little over 24 hours afterward, I went back into a steady sinus rhythm during a good hot shower, with a pleasant Ahhhh sensation, and nothing since.

No doubt the adrenaline from the fall drove my heart rate up.

Because I had gone 30 years without AFIB (that earlier case came from a heart infection), even after plenty of dirt bike wrecks, SeaDoo wave jumping and racing chaos, and bicycle racing crashes with fractures, I believe Retatrutide tipped me past the limit. I had just increased to 5mg/wk, which appears to be my maintenance dose. On Reta my resting heart rate is probably above my fit-normal, though I can't say by how much. It was also elevated when my weight was higher. Perhaps 82bpm either way. Fat, or on Reta.

QueenMuntha said:

Reta seems to set off AFib episodes even at .5mg per week, triggered by minor things such as eating tomato sauce or having food within 6 hours of going to bed. None of this occurred prior to when I reintroduced small Reta doses, after having quit it because of back pain tied to the gall bladder.

I'm not claiming correlation equals causation, but it is mighty peculiar. This is my 5am Kardia reading on Wed, following spaghetti and meatballs with tomato sauce at 5pm. (200 mg of Flecainide settled it after 2 hours.)

SeaGypsy said:

At a 2.5mg low dose of Reta, I ran into heart rate problems. Even while just sitting around watching television, my readings would occasionally jump into the 130s and 140s. After switching back to Tirz, everything returned to normal.

I have a question for each of you:

Are magnesium and potassium part of your daily routine? Which supplements are you on, and is there anything you take specifically to support heart health?

Nope, I don't take any supplements. My regimen is just 75mg Metoprolol, 50 mg Flecainide bid and Xarelto.

Magnesium didn't do anything for me when I gave it a shot. That said, prior to starting Reta, my AFib episodes were only around 3 times/year. Oh, and I can't forget my trusty CPAP.

That's rough. At the very least, if nothing else, I'd strongly urge you to start taking 200mg of elemental magnesium daily in the form of magnesium glycinate. Both Doctor's Best and Now Foods are solid choices.

QueenMuntha said:

birdwhacker said:

cujet said:

62M, used to be an athlete. Weight now holds around 192 pounds (roughly where I want to be), previously 262. Still strong and able to go slow for long stretches, even with several autoimmune conditions. Those conditions triggered AFIB 30 years back. Nothing since then, until this happened.

I was up on my moving truck and tumbled out of the cab, roughly 6 feet to the ground. I had been putting together a platform for my puppy, stepped off it, and missed the foothold. My headphones smashed against a nearby tree (that's what kept me from getting hurt), then I struck the truck, then landed. I ended up battered and scraped. The series of impacts is what stopped any bones from breaking, since each one slowed the fall.

Right away my pulse jumped to 160 and would not come down. I stayed on the ground for 30 minutes hoping it would calm. My Apple watch flagged AFIB along with a high rate that was gradually dropping. The next night, a little over 24 hours afterward, I went back into a steady sinus rhythm during a good hot shower, with a pleasant Ahhhh sensation, and nothing since.

No doubt the adrenaline from the fall drove my heart rate up.

Because I had gone 30 years without AFIB (that earlier case came from a heart infection), even after plenty of dirt bike wrecks, SeaDoo wave jumping and racing chaos, and bicycle racing crashes with fractures, I believe Retatrutide tipped me past the limit. I had just increased to 5mg/wk, which appears to be my maintenance dose. On Reta my resting heart rate is probably above my fit-normal, though I can't say by how much. It was also elevated when my weight was higher. Perhaps 82bpm either way. Fat, or on Reta.

QueenMuntha said:

Reta seems to set off AFib episodes even at .5mg per week, triggered by minor things such as eating tomato sauce or having food within 6 hours of going to bed. None of this occurred prior to when I reintroduced small Reta doses, after having quit it because of back pain tied to the gall bladder.

I'm not claiming correlation equals causation, but it is mighty peculiar. This is my 5am Kardia reading on Wed, following spaghetti and meatballs with tomato sauce at 5pm. (200 mg of Flecainide settled it after 2 hours.)

SeaGypsy said:

At a 2.5mg low dose of Reta, I ran into heart rate problems. Even while just sitting around watching television, my readings would occasionally jump into the 130s and 140s. After switching back to Tirz, everything returned to normal.

I have a question for each of you:

Are magnesium and potassium part of your daily routine? Which supplements are you on, and is there anything you take specifically to support heart health?

Nope, I don't take any supplements. My regimen is just 75mg Metoprolol, 50 mg Flecainide bid and Xarelto.

Magnesium didn't do anything for me when I gave it a shot. That said, prior to starting Reta, my AFib episodes were only around 3 times/year. Oh, and I can't forget my trusty CPAP.

Xarelto—ha, that brings back memories. I ended up with an embolism after the covid vaccine a few years ago. My mom had to grab a sample for me from one of her offices since the doctor I saw afterward refused to prescribe it, doubting my account. Good times. I was on it for 3 months, plus a ton of NAC, natto, fish oil, iodine, vitamin D, and zinc.

If you're on a blood thinner, adding omega 3 is wise too. Now Foods Liquid is the most budget-friendly, but if you're feeling fancy, go for Nordic Naturals.

QueenMuntha said:

birdwhacker said:

cujet said:

62M, used to be an athlete. Weight now holds around 192 pounds (roughly where I want to be), previously 262. Still strong and able to go slow for long stretches, even with several autoimmune conditions. Those conditions triggered AFIB 30 years back. Nothing since then, until this happened.

I was up on my moving truck and tumbled out of the cab, roughly 6 feet to the ground. I had been putting together a platform for my puppy, stepped off it, and missed the foothold. My headphones smashed against a nearby tree (that's what kept me from getting hurt), then I struck the truck, then landed. I ended up battered and scraped. The series of impacts is what stopped any bones from breaking, since each one slowed the fall.

Right away my pulse jumped to 160 and would not come down. I stayed on the ground for 30 minutes hoping it would calm. My Apple watch flagged AFIB along with a high rate that was gradually dropping. The next night, a little over 24 hours afterward, I went back into a steady sinus rhythm during a good hot shower, with a pleasant Ahhhh sensation, and nothing since.

No doubt the adrenaline from the fall drove my heart rate up.

Because I had gone 30 years without AFIB (that earlier case came from a heart infection), even after plenty of dirt bike wrecks, SeaDoo wave jumping and racing chaos, and bicycle racing crashes with fractures, I believe Retatrutide tipped me past the limit. I had just increased to 5mg/wk, which appears to be my maintenance dose. On Reta my resting heart rate is probably above my fit-normal, though I can't say by how much. It was also elevated when my weight was higher. Perhaps 82bpm either way. Fat, or on Reta.

QueenMuntha said:

Reta seems to set off AFib episodes even at .5mg per week, triggered by minor things such as eating tomato sauce or having food within 6 hours of going to bed. None of this occurred prior to when I reintroduced small Reta doses, after having quit it because of back pain tied to the gall bladder.

I'm not claiming correlation equals causation, but it is mighty peculiar. This is my 5am Kardia reading on Wed, following spaghetti and meatballs with tomato sauce at 5pm. (200 mg of Flecainide settled it after 2 hours.)

SeaGypsy said:

At a 2.5mg low dose of Reta, I ran into heart rate problems. Even while just sitting around watching television, my readings would occasionally jump into the 130s and 140s. After switching back to Tirz, everything returned to normal.

I have a question for each of you:

Are magnesium and potassium part of your daily routine? Which supplements are you on, and is there anything you take specifically to support heart health?

Nope, I don't take any supplements. My regimen is just 75mg Metoprolol, 50 mg Flecainide bid and Xarelto.

Magnesium didn't do anything for me when I gave it a shot. That said, prior to starting Reta, my AFib episodes were only around 3 times/year. Oh, and I can't forget my trusty CPAP.

There are times I don't notice a change after brushing my teeth, but you still need to do it at least a few times a week. That's just basic self-care. Skipping all supplements seems insane to me.

No, I gave it a shot several years back, but these days my Chronic Kidney Disease means I can't risk magnesium or various other things. I once used magnesium for really bad muscle cramps, and it made zero difference.

Omega 3 is off the table too, since it thins the blood.

I appreciate the suggestions, but I'm fine skipping the supplements. Peptides, on the other hand—bring them on.

 

[birdwhacker]

Grim.

 

[myboysherman]

After 1 week on Reta, I experienced fairly severe palpitations. The "Health monitor" triggered alerts for afib and flutter, plus nearly every other condition, though it has given false readings before. I tried magnesium, which had helped at times previously, but it did not this time or recently. Mg and potassium electrolyte mixes made a huge difference—better than in years. I suspect a potato or banana might have helped too.

 

[birdwhacker]

myboysherman said:

After 1 week on Reta, I experienced fairly severe palpitations. The "Health monitor" triggered alerts for afib and flutter, plus nearly every other condition, though it has given false readings before. I tried magnesium, which had helped at times previously, but it did not this time or recently. Mg and potassium electrolyte mixes made a huge difference—better than in years. I suspect a potato or banana might have helped too.

For me, potassium made a huge difference. I take at least 1 gram every day. I also had to stop using nicotine and caffeine.

 

[cujet]

Apologies for taking so long to get back. There is a cardiologist I see, and I got in touch with him right away; we had a thorough discussion about it. According to him, catecholamines can set off a rapid heart rate when that kind of injury is present. That the Apple watch flagged AFIB didn't shock him, and he was emphatic that I should head to the ER if things didn't calm down fast, since the window for either spontaneous or cardio-reversion is 48 hours. I chose not to go to the ER because my heart rate was gradually dropping and hitting normal ranges more frequently. Waiting a little was my call. When I asked about stroke risk, I was told the risk early on is fairly low. Aspirin was something I took. Stroke risk from AFIB builds up over time.

Since things reverted, nothing has come up. I haven't been using magnesium or potassium supplement pills, but I do drink Brawndo electrolyte drink (Nutricost electrolytes) on a regular basis. The amounts in it are modest.

These past two weeks I've been loading and unloading my moving truck, and my heart is behaving normally. Given that I'm a former athlete and bicycle racer with a 0 calcium score, pushing my heart through exercise doesn't (so far?) bring on chest pain. Tomorrow I might try a bicycle ride as a test. Lately I've been feeling quite good.

 

[RetCurious]

myboysherman said:

After 1 week on Reta, I experienced fairly severe palpitations. The "Health monitor" triggered alerts for afib and flutter, plus nearly every other condition, though it has given false readings before. I tried magnesium, which had helped at times previously, but it did not this time or recently. Mg and potassium electrolyte mixes made a huge difference—better than in years. I suspect a potato or banana might have helped too.

"One medium banana carries roughly 450 milligrams of potassium."

"A medium baked potato, skin included, carries roughly 926 mg of potassium."

Never knew a potato outranks a banana on potassium.

 

[RetCurious]

cujet said:

Apologies for taking so long to get back. There is a cardiologist I see, and I got in touch with him right away; we had a thorough discussion about it. According to him, catecholamines can set off a rapid heart rate when that kind of injury is present. That the Apple watch flagged AFIB didn't shock him, and he was emphatic that I should head to the ER if things didn't calm down fast, since the window for either spontaneous or cardio-reversion is 48 hours. I chose not to go to the ER because my heart rate was gradually dropping and hitting normal ranges more frequently. Waiting a little was my call. When I asked about stroke risk, I was told the risk early on is fairly low. Aspirin was something I took. Stroke risk from AFIB builds up over time.

Since things reverted, nothing has come up. I haven't been using magnesium or potassium supplement pills, but I do drink Brawndo electrolyte drink (Nutricost electrolytes) on a regular basis. The amounts in it are modest.

These past two weeks I've been loading and unloading my moving truck, and my heart is behaving normally. Given that I'm a former athlete and bicycle racer with a 0 calcium score, pushing my heart through exercise doesn't (so far?) bring on chest pain. Tomorrow I might try a bicycle ride as a test. Lately I've been feeling quite good.

Every day I take 1/2 of a baby aspirin, for no particular reason.

"Aspirin is recommended for individuals aged 40 to 59 with a 10% or greater 10-year cardiovascular disease risk, but not for those aged 60 and older without a history of heart disease due to increased bleeding risks."

My guess is that by 60, most of us have developed some form of "heart disease"?

 

[ProblemChild]

myboysherman said:

After 1 week on Reta, I experienced fairly severe palpitations. The "Health monitor" triggered alerts for afib and flutter, plus nearly every other condition, though it has given false readings before. I tried magnesium, which had helped at times previously, but it did not this time or recently. Mg and potassium electrolyte mixes made a huge difference—better than in years. I suspect a potato or banana might have helped too.

How much were you taking? I'm in my late 50s, and I had an ablation in 2021. I'm being extremely cautious with my Reta titration. This clip discusses Taurine supplementation during Reta use.

 

[myboysherman]

ProblemChild said:

myboysherman said:

After 1 week on Reta, I experienced fairly severe palpitations. The "Health monitor" triggered alerts for afib and flutter, plus nearly every other condition, though it has given false readings before. I tried magnesium, which had helped at times previously, but it did not this time or recently. Mg and potassium electrolyte mixes made a huge difference—better than in years. I suspect a potato or banana might have helped too.

How much were you taking? I'm in my late 50s, and I had an ablation in 2021. I'm being extremely cautious with my Reta titration. This clip discusses Taurine supplementation during Reta use.

My beginning dose was 1mg, taken 2 times per week. At present I've worked my way to roughly 6mg/week. When I increased last time, I went too fast and the palpitations came back. On how slowly to move up, I'm with you. Rather than jumping doses the way the studies do, I'll take it gradually, since the amount isn't what causes trouble — it's how quickly I get to it.

Thanks for the pointer; I'll look at that Taurine video.