65-year-old with a 2-year-old granddaughter, aiming to stay healthy, active, and mentally sharp as long as I can. Hit goal weight on tirzepatide—what

[pumpkinpie]

I dropped ~60lbs. on trz while never exceeding 5mg/week, and it took roughly 6.5 months. My doctor called me a 'super responder' and instructed me (and noted in my chart) to quit tirzepitide right away and put back on no less than 10 lbs. At 5'6" and 135 lbs, I was hoping to shed another 5 pounds, but given my age he's concerned about muscle and bone loss - I completely get it, yet I'm extremely physically active (I use the Dr. Vonda Wright FACE framework) and I'm in the best shape I've been in since I ran track in hs. A recent dexa scan showed sarcopenia, but nothing out of the ordinary for my age. My worry is regaining weight, and ever since I stopped the trz, all the inflammation I had before trz has returned (wrists, hands, hips, neck stiffness and inflammation). I want to look into ways to keep my weight stable if it starts climbing, look into HRT (am I too old to start?), and anything to do with muscle and bone loss. And if anybody has found the fountain of youth - I'd like to look into that as well............

I'd love to hear about the successes and challenges others have had.

 

[Blueeyedme]

Glad you're here! My suggestion is to look into a maintenance dose of tirzepatide, or perhaps micro dosing, so you can keep enjoying everything tirzepatide provides without either losing or gaining weight. Naturally, this isn't medical advice.

 

[Peptidio_Banderas]

That's wonderful. My mom is 75 and has two grandsons, 3 and 5 years old. For their sake, she's also working to remain as active as she can for as long as possible. That's truly fantastic.

A microdose of TRZ might be worth trying. Should you be a "super responder," taking 2 mg or 2.5 mg every 10 to 14 days could be sufficient to hold your weight steady and silence the "food noise." Still, the right approach is something only you can determine.

I'm also a strong responder. For me, even 1.25mg to 2mg every 10 days does the job. That said, I'm somewhat younger and I work out frequently. Even so, without TRZ's support, things become very difficult, particularly in terms of mental state and during the night.

Best of luck!

 

[pumpkinpie]

Thanks! Given how well I did on it previously, I believe that approach could suit me. Since dropping the weight, every aspect of my life has gotten better and I'm in a much improved place, and I'd like to maintain that momentum. I stay quite active, though I'd also appreciate any guidance on preserving muscle mass and reducing bone loss. In that context, would a low dose of reta offer more advantages than tirzepatide? Or is there something else worth adding? I've only just begun reading up on KLOW too. There's plenty for me to learn. Thanks again!

 

[pumpkinpie]

Peptidio_Banderas said:

That's wonderful. My mom is 75 and has two grandsons, 3 and 5 years old. For their sake, she's also working to remain as active as she can for as long as possible. That's truly fantastic.

A microdose of TRZ might be worth trying. Should you be a "super responder," taking 2 mg or 2.5 mg every 10 to 14 days could be sufficient to hold your weight steady and silence the "food noise." Still, the right approach is something only you can determine.

I'm also a strong responder. For me, even 1.25mg to 2mg every 10 days does the job. That said, I'm somewhat younger and I work out frequently. Even so, without TRZ's support, things become very difficult, particularly in terms of mental state and during the night.

Best of luck!

I appreciate you sharing this—it's encouraging to hear that people in my age group are working toward the same goals. Great job to both you and your mother!

 

[pepsrjstsmllproteins]

Muscle mass shrinking is among the leading causes behind sickness, the need for extended care, and mortality itself. When balance fails or someone falls, they can end up confined to bed for extended stretches, and in the case of wasting conditions such as cancer, having less muscle correlates with a greater risk of dying. Sarcopenia is something you've already been told you have. A major drawback of GLP-1/GIP and other highly effective weight-loss drugs is the loss of muscle that comes from eating too little protein and nutrients while also moving too little. For older adults who want more years and better health, the most crucial piece of advice anyone can offer is this: begin strength training. Movement shouldn't scare you, heavy weights shouldn't scare you, and injury shouldn't scare you. Don't let magazines or strangers steer you toward different forms of exercise instead — yes, those have benefits too, but nothing builds muscle more effectively than strength training. Join a gym, preferably one with skilled trainers, perhaps even those whose expertise is in training older adults, and work every muscle group a minimum of 2 times each week. Begin gradually at only 4 sets weekly per muscle group, keep reps between 6 and 12, and once more, heavy weight is nothing to fear provided your form holds up. Have someone demonstrate and describe correct form, use machines initially, and remain consistent. Whether you're using GLPs or following other diets, aim to meet your protein requirements — a solid guideline is about 1.6g/kg of bodyweight (approximately 0.7g for every lb of bodyweight).

 

[lemonadegin29]

Hello, and I hope things keep going well for you on your path!

 

[pumpkinpie]

pepsrjstsmllproteins said:

Muscle mass shrinking is among the leading causes behind sickness, the need for extended care, and mortality itself. When balance fails or someone falls, they can end up confined to bed for extended stretches, and in the case of wasting conditions such as cancer, having less muscle correlates with a greater risk of dying. Sarcopenia is something you've already been told you have. A major drawback of GLP-1/GIP and other highly effective weight-loss drugs is the loss of muscle that comes from eating too little protein and nutrients while also moving too little. For older adults who want more years and better health, the most crucial piece of advice anyone can offer is this: begin strength training. Movement shouldn't scare you, heavy weights shouldn't scare you, and injury shouldn't scare you. Don't let magazines or strangers steer you toward different forms of exercise instead — yes, those have benefits too, but nothing builds muscle more effectively than strength training. Join a gym, preferably one with skilled trainers, perhaps even those whose expertise is in training older adults, and work every muscle group a minimum of 2 times each week. Begin gradually at only 4 sets weekly per muscle group, keep reps between 6 and 12, and once more, heavy weight is nothing to fear provided your form holds up. Have someone demonstrate and describe correct form, use machines initially, and remain consistent. Whether you're using GLPs or following other diets, aim to meet your protein requirements — a solid guideline is about 1.6g/kg of bodyweight (approximately 0.7g for every lb of bodyweight).

I really appreciate you sharing this! For several years I was into crossfit, but once COVID hit I quit completely. I stopped doing everything—I wouldn't even go for a walk. That was a serious error on my part, and these days I'm putting in a lot of effort to build and keep muscle. The hardest part for me is making it a regular, everyday habit again. What you've said gives me motivation. Thank you.

 

[pepsrjstsmllproteins]

pumpkinpie said:

pepsrjstsmllproteins said:

Muscle mass shrinking is among the leading causes behind sickness, the need for extended care, and mortality itself. When balance fails or someone falls, they can end up confined to bed for extended stretches, and in the case of wasting conditions such as cancer, having less muscle correlates with a greater risk of dying. Sarcopenia is something you've already been told you have. A major drawback of GLP-1/GIP and other highly effective weight-loss drugs is the loss of muscle that comes from eating too little protein and nutrients while also moving too little. For older adults who want more years and better health, the most crucial piece of advice anyone can offer is this: begin strength training. Movement shouldn't scare you, heavy weights shouldn't scare you, and injury shouldn't scare you. Don't let magazines or strangers steer you toward different forms of exercise instead — yes, those have benefits too, but nothing builds muscle more effectively than strength training. Join a gym, preferably one with skilled trainers, perhaps even those whose expertise is in training older adults, and work every muscle group a minimum of 2 times each week. Begin gradually at only 4 sets weekly per muscle group, keep reps between 6 and 12, and once more, heavy weight is nothing to fear provided your form holds up. Have someone demonstrate and describe correct form, use machines initially, and remain consistent. Whether you're using GLPs or following other diets, aim to meet your protein requirements — a solid guideline is about 1.6g/kg of bodyweight (approximately 0.7g for every lb of bodyweight).

I really appreciate you sharing this! For several years I was into crossfit, but once COVID hit I quit completely. I stopped doing everything—I wouldn't even go for a walk. That was a serious error on my part, and these days I'm putting in a lot of effort to build and keep muscle. The hardest part for me is making it a regular, everyday habit again. What you've said gives me motivation. Thank you.

This resonates with me a lot. There were probably 10 years where I kept beginning and then quitting — the gym, but also healthy habits and taking care of myself in general — right up until roughly 3 years ago, when I began and simply didn't stop. During those first weeks it was nothing but stubbornness, a refusal to give up, yet each week that went by became slightly less difficult, and eventually I found myself genuinely liking the gym and all that goes along with it. Nowadays I don't even ask myself whether I'm going to the gym — it has turned into something as routine as brushing my teeth, buying groceries, or handling laundry. In my view, many people survive the beginning only through sheer discipline and willpower, but you're able to make the entire process as simple as possible for yourself — what matters most is not making things too complicated early on, keeping to the basics, and most importantly, staying consistent. More can always be added later, but the real progress comes from those fundamentals. What's wonderful about this sport is that no innate talent is needed, and genuine improvement can still show up in only a few weeks to months. If Crossfit worked for you in the past and you got at least some enjoyment out of it, that might be an excellent route back in. I hope things go well for you, and I wish you the very best on your fitness journey!

 

[cujet]

Muscle equals lifespan, and lifting weights is the top approach. I'm an older guy dealing with an extreme amount of health issues. To keep my weight at a sensible level, I'm on Retatrutide. Peptides for telomere extension and other life-extension avenues might be worth exploring. Lately I've been through an absolute nightmare with autoimmune conditions flaring out of control.

Hashimoto's thyroid failure.

Sec Adrl Insf, severe, zero cortisol (life threatening)

MCTD (like lupus)

Possible MG (muscle/nerve interface issues)(muscle failure)

What I've come to understand is that peptides won't cure anything, but they can target inflammation, and that alone is a massive relief.

 

[pumpkinpie]

pepsrjstsmllproteins said:

pumpkinpie said:

pepsrjstsmllproteins said:

Muscle mass shrinking is among the leading causes behind sickness, the need for extended care, and mortality itself. When balance fails or someone falls, they can end up confined to bed for extended stretches, and in the case of wasting conditions such as cancer, having less muscle correlates with a greater risk of dying. Sarcopenia is something you've already been told you have. A major drawback of GLP-1/GIP and other highly effective weight-loss drugs is the loss of muscle that comes from eating too little protein and nutrients while also moving too little. For older adults who want more years and better health, the most crucial piece of advice anyone can offer is this: begin strength training. Movement shouldn't scare you, heavy weights shouldn't scare you, and injury shouldn't scare you. Don't let magazines or strangers steer you toward different forms of exercise instead — yes, those have benefits too, but nothing builds muscle more effectively than strength training. Join a gym, preferably one with skilled trainers, perhaps even those whose expertise is in training older adults, and work every muscle group a minimum of 2 times each week. Begin gradually at only 4 sets weekly per muscle group, keep reps between 6 and 12, and once more, heavy weight is nothing to fear provided your form holds up. Have someone demonstrate and describe correct form, use machines initially, and remain consistent. Whether you're using GLPs or following other diets, aim to meet your protein requirements — a solid guideline is about 1.6g/kg of bodyweight (approximately 0.7g for every lb of bodyweight).

I really appreciate you sharing this! For several years I was into crossfit, but once COVID hit I quit completely. I stopped doing everything—I wouldn't even go for a walk. That was a serious error on my part, and these days I'm putting in a lot of effort to build and keep muscle. The hardest part for me is making it a regular, everyday habit again. What you've said gives me motivation. Thank you.

This resonates with me a lot. There were probably 10 years where I kept beginning and then quitting — the gym, but also healthy habits and taking care of myself in general — right up until roughly 3 years ago, when I began and simply didn't stop. During those first weeks it was nothing but stubbornness, a refusal to give up, yet each week that went by became slightly less difficult, and eventually I found myself genuinely liking the gym and all that goes along with it. Nowadays I don't even ask myself whether I'm going to the gym — it has turned into something as routine as brushing my teeth, buying groceries, or handling laundry. In my view, many people survive the beginning only through sheer discipline and willpower, but you're able to make the entire process as simple as possible for yourself — what matters most is not making things too complicated early on, keeping to the basics, and most importantly, staying consistent. More can always be added later, but the real progress comes from those fundamentals. What's wonderful about this sport is that no innate talent is needed, and genuine improvement can still show up in only a few weeks to months. If Crossfit worked for you in the past and you got at least some enjoyment out of it, that might be an excellent route back in. I hope things go well for you, and I wish you the very best on your fitness journey!

Thanks for the kind words. Sounds like things are going really well for you!

 

[pumpkinpie]

cujet said:

Muscle equals lifespan, and lifting weights is the top approach. I'm an older guy dealing with an extreme amount of health issues. To keep my weight at a sensible level, I'm on Retatrutide. Peptides for telomere extension and other life-extension avenues might be worth exploring. Lately I've been through an absolute nightmare with autoimmune conditions flaring out of control.

Hashimoto's thyroid failure.

Sec Adrl Insf, severe, zero cortisol (life threatening)

MCTD (like lupus)

Possible MG (muscle/nerve interface issues)(muscle failure)

What I've come to understand is that peptides won't cure anything, but they can target inflammation, and that alone is a massive relief.

I'm grateful you posted this. What I'm dealing with doesn't come close to what you've been through - you're an inspiration to me! My priority now, I believe, has to be tackling the inflammation head-on. It has a ripple effect on everything else - lifting, sleeping, etc. Wishing you well, and please stay in touch.