Appreciate you sharing your experience with tirz at high doses, along with the other compounds. With virtually no published data to go on, personal accounts posted online are basically all we have when it comes to larger doses and stacking weight loss peptides, and some of us dealing with severe obesity or who don't get much of a response from GLPs have nothing solid to guide our choices.
Compared with the 16mg semaglutide trial, 60 mg of tirz doesn't seem all that far out there. If you scale 2.4mg:15mg up, that works out to 16mg sema matching 100mg of tirz. Still, my guess is a person would need to be pretty insensitive to the stuff for side effects not to become a big problem at those amounts. For me, at 15mg tirz with 6 mg of reta, adding even 1mg more of either one gives me that crawling skin feeling, so I'm clearly at my ceiling.