Your brain on COVID

Chili777

Explorer
Joined
Oct 31, 2025
Messages
816
Reaction score
836
Location
USA
A recent piece covering new COVID findings and how the virus impacts the brain caught my attention. Even though it has dropped off the front pages, scientists continue working to pin down exactly which alterations COVID infection leaves behind in the brain. My own reason for digging into this topic comes from the lingering brain fog I deal with after having had COVID twice.



e96e2e4c5d085096dae1697dc3fe6f79a48b4d589f18163fb909bfd731975dba.jpg




Brain scans reveal widespread structural and functional changes in patients following COVID-19 infection



A review covering 49 imaging studies sheds light on how COVID-19 impacts the human brain. The researchers documented broad structural and functional shifts in regions tied to memory, emotion, and attention, which helps explain persistent neurological complaints such as brain fog.

6fa76a95849a5a7b090ce5fa38af375365bada393f7ad615ddea05cfc05aa480.png



www.psypost.org
 
Among people I know, I haven't observed lasting cognitive problems, yet a number of them suffer from irreversible hearing damage, high blood pressure in the lungs, and heart complications—each condition linked squarely to severe COVID episodes. And it's not over: where I live, COVID cases are climbing again as we speak.
 
Chili777 said:

A recent piece covering new COVID findings and how the virus impacts the brain caught my attention. Even though it has dropped off the front pages, scientists continue working to pin down exactly which alterations COVID infection leaves behind in the brain. My own reason for digging into this topic comes from the lingering brain fog I deal with after having had COVID twice.



View attachment 370



Brain scans reveal widespread structural and functional changes in patients following COVID-19 infection



A review covering 49 imaging studies sheds light on how COVID-19 impacts the human brain. The researchers documented broad structural and functional shifts in regions tied to memory, emotion, and attention, which helps explain persistent neurological complaints such as brain fog.

View attachment 371


www.psypost.org

Thanks for posting this—it's a fascinating read.

Could covid be behind my tiredness, the trouble with my inner ear, and this general foggy feeling in my head 🤣?

Up to now, I'd been putting the blame on cagri.
 

Attachments

  • e96e2e4c5d085096dae1697dc3fe6f79a48b4d589f18163fb909bfd731975dba.jpg
    e96e2e4c5d085096dae1697dc3fe6f79a48b4d589f18163fb909bfd731975dba.jpg
    216.3 KB · Views: 33
  • 6fa76a95849a5a7b090ce5fa38af375365bada393f7ad615ddea05cfc05aa480.png
    6fa76a95849a5a7b090ce5fa38af375365bada393f7ad615ddea05cfc05aa480.png
    752 bytes · Views: 25
At this point there have been no fewer than 12 Covid waves, and the majority arrived after the pandemic was declared "over." Even so, Long Covid and other fallout from the illness keep appearing in people. Nothing suggests this pattern is winding down; at minimum, we are still seeing a summer wave and a winter wave. Roughly 500,000 scientific papers now exist on Covid and Long Covid, and all of them document the harms Covid causes us. Not a single one indicates that catching it is a good idea!

I am among those with Long Covid, having contracted it during the first wave in 2020. It has been an absolute nightmare. Many people near me do not realize how much damage Covid inflicts, and you can observe them struggling in different ways, frequently with neurological problems. The disease has caused genuine harm to those who ignore it, and I wish more people would take steps to safeguard their health.
 
Grogu said:

Chili777 said:

A recent piece covering new COVID findings and how the virus impacts the brain caught my attention. Even though it has dropped off the front pages, scientists continue working to pin down exactly which alterations COVID infection leaves behind in the brain. My own reason for digging into this topic comes from the lingering brain fog I deal with after having had COVID twice.



View attachment 370



Brain scans reveal widespread structural and functional changes in patients following COVID-19 infection



A review covering 49 imaging studies sheds light on how COVID-19 impacts the human brain. The researchers documented broad structural and functional shifts in regions tied to memory, emotion, and attention, which helps explain persistent neurological complaints such as brain fog.

View attachment 371


www.psypost.org

Thanks for posting this—it's a fascinating read.

Could covid be behind my tiredness, the trouble with my inner ear, and this general foggy feeling in my head 🤣?

Up to now, I'd been putting the blame on cagri.
That research does make it a real possibility. What I know for certain is that covid marked a dividing line for me: the person I was before is not the person I am now. Brain fog and trouble concentrating are among the changes, and I have been trying to address them from that point on. It resembles ADHD in some ways, yet it is not the same, and it appeared when I was in my 60s. Strange.
 
Chili777 said:

Grogu said:

Chili777 said:

A recent piece covering new COVID findings and how the virus impacts the brain caught my attention. Even though it has dropped off the front pages, scientists continue working to pin down exactly which alterations COVID infection leaves behind in the brain. My own reason for digging into this topic comes from the lingering brain fog I deal with after having had COVID twice.



View attachment 370



Brain scans reveal widespread structural and functional changes in patients following COVID-19 infection



A review covering 49 imaging studies sheds light on how COVID-19 impacts the human brain. The researchers documented broad structural and functional shifts in regions tied to memory, emotion, and attention, which helps explain persistent neurological complaints such as brain fog.

View attachment 371


www.psypost.org

Thanks for posting this—it's a fascinating read.

Could covid be behind my tiredness, the trouble with my inner ear, and this general foggy feeling in my head 🤣?

Up to now, I'd been putting the blame on cagri.
That research does make it a real possibility. What I know for certain is that covid marked a dividing line for me: the person I was before is not the person I am now. Brain fog and trouble concentrating are among the changes, and I have been trying to address them from that point on. It resembles ADHD in some ways, yet it is not the same, and it appeared when I was in my 60s. Strange.

Joking aside, something about my cognition does feel different, though I had chalked that up to peptides instead of COVID. Looks like I need to dig into this further.

Modafinil has been a big help for me. The few times I've used it, my productivity jumped, my thinking became razor sharp, and I felt great. For various reasons, though, I'm hesitant to use it regularly. I even split the tablet into 1/2, and the result was still excellent. It's been 2 years since my head felt this clear.
 
Grogu said:

Chili777 said:

Grogu said:

Chili777 said:

A recent piece covering new COVID findings and how the virus impacts the brain caught my attention. Even though it has dropped off the front pages, scientists continue working to pin down exactly which alterations COVID infection leaves behind in the brain. My own reason for digging into this topic comes from the lingering brain fog I deal with after having had COVID twice.



View attachment 370



Brain scans reveal widespread structural and functional changes in patients following COVID-19 infection



A review covering 49 imaging studies sheds light on how COVID-19 impacts the human brain. The researchers documented broad structural and functional shifts in regions tied to memory, emotion, and attention, which helps explain persistent neurological complaints such as brain fog.

View attachment 371


www.psypost.org

Thanks for posting this—it's a fascinating read.

Could covid be behind my tiredness, the trouble with my inner ear, and this general foggy feeling in my head 🤣?

Up to now, I'd been putting the blame on cagri.
That research does make it a real possibility. What I know for certain is that covid marked a dividing line for me: the person I was before is not the person I am now. Brain fog and trouble concentrating are among the changes, and I have been trying to address them from that point on. It resembles ADHD in some ways, yet it is not the same, and it appeared when I was in my 60s. Strange.

Joking aside, something about my cognition does feel different, though I had chalked that up to peptides instead of COVID. Looks like I need to dig into this further.

Modafinil has been a big help for me. The few times I've used it, my productivity jumped, my thinking became razor sharp, and I felt great. For various reasons, though, I'm hesitant to use it regularly. I even split the tablet into 1/2, and the result was still excellent. It's been 2 years since my head felt this clear.
Modafinil has gotten positive feedback, so I'll check into that. Epitalon has been through 3 of my cycles, and NA Epi Amidate is what I'm currently using. P21 IN was also part of a 1-month run for me, plus more recently I gave Noopept and Piracetam a try. Each appears to deliver benefits, though they hold up only while they're active. Since peptides act as signalling molecules, the signalling continues only so long as they stay active. My conclusion is that a lasting effect isn't something any of them truly provide. That just means I need to plan around it and figure out which option suits me when used on a semi-regular basis.
 
I really relate to this. @Grogu and @Chili777, the two of you included, I can recall a time before this constant mental haze settled in, when concentrating and thinking came easily. Getting through work feels like a battle, and what I want most is simply to stop feeling exhausted (changing how long or how well I sleep doesn't appear to change anything) and to stay focused long enough to finish my tasks. Modafinil appeals to me, though I hesitate because it might do exactly what I need and then I'd end up taking it every weekday, or more. Surely there's an option that's gentler yet still provides a bit of a boost. Last year I bought a Semax kit hoping it would do something, but after roughly 2 weeks I felt nothing aside from a really dry nose.

I believe this ties strongly to the COVID I had 4 years ago. Since that time my WBC count has stayed low, and while my PCP keeps an eye on it, he tells me medication isn't necessary yet. That's the reason I now take KPV every day, plus TA-1 2x/week, because I want to do everything possible to bring inflammation down and strengthen my anti-inflammatory response when I get sick.

Motivation is another thing that takes a hit. Once I'm at the gym I'm fine, but summoning the energy to actually get there is its own mental exertion.

And honestly, as much as I enjoy a good nap with my cat, it's rough that the moment I wake up each day, my first thought is about when I can fit in another nap later. 😹
 
ThatNextGril said:

I really relate to this. @Grogu and @Chili777, the two of you included, I can recall a time before this constant mental haze settled in, when concentrating and thinking came easily. Getting through work feels like a battle, and what I want most is simply to stop feeling exhausted (changing how long or how well I sleep doesn't appear to change anything) and to stay focused long enough to finish my tasks. Modafinil appeals to me, though I hesitate because it might do exactly what I need and then I'd end up taking it every weekday, or more. Surely there's an option that's gentler yet still provides a bit of a boost. Last year I bought a Semax kit hoping it would do something, but after roughly 2 weeks I felt nothing aside from a really dry nose.

I believe this ties strongly to the COVID I had 4 years ago. Since that time my WBC count has stayed low, and while my PCP keeps an eye on it, he tells me medication isn't necessary yet. That's the reason I now take KPV every day, plus TA-1 2x/week, because I want to do everything possible to bring inflammation down and strengthen my anti-inflammatory response when I get sick.

Motivation is another thing that takes a hit. Once I'm at the gym I'm fine, but summoning the energy to actually get there is its own mental exertion.

And honestly, as much as I enjoy a good nap with my cat, it's rough that the moment I wake up each day, my first thought is about when I can fit in another nap later. 😹
Semax works for me, though you need 1 mg — SQ or IN — before it really takes hold. Adamax strikes me as a far better option, except that the maximum cycle is 30 days, and after two weeks my receptors have already gone dull, so I bump the dose from 350 mcg up to 500 mcg. Then what do you do during the remaining washout time? Pairing P21 with Adamax works really well, and I'll stick with that, though the cycle limits are identical.

Below I've got a link to a Modafinil guide. From what I can tell, its main action is on concentration, with a bit of a motivational boost. The schedule is 5 days on/2 days off, plus a 1 week wash out if you use it long term, and you absolutely need choline supplementation. It isn't cheap either, but I'll look into it.



8f1e57f5b61602264778db4ddad184c0b3c0c57253f2a6336a03b9e0b0773160.jpg




How to Take Modafinil Effectively | 16 Quick Tips and Tricks



Curious how to take Modafinil effectively? In the #1 GUIDE on getting the most of Modafinil, you'll find the best tips and tricks for smart drug users.

55e05e60ab531a08044fa48bfcab1d57ff1c29b5105c605518b49c0017877f88.png



www.modafinil.com
 
Chili777 said:

ThatNextGril said:

I really relate to this. @Grogu and @Chili777, the two of you included, I can recall a time before this constant mental haze settled in, when concentrating and thinking came easily. Getting through work feels like a battle, and what I want most is simply to stop feeling exhausted (changing how long or how well I sleep doesn't appear to change anything) and to stay focused long enough to finish my tasks. Modafinil appeals to me, though I hesitate because it might do exactly what I need and then I'd end up taking it every weekday, or more. Surely there's an option that's gentler yet still provides a bit of a boost. Last year I bought a Semax kit hoping it would do something, but after roughly 2 weeks I felt nothing aside from a really dry nose.

I believe this ties strongly to the COVID I had 4 years ago. Since that time my WBC count has stayed low, and while my PCP keeps an eye on it, he tells me medication isn't necessary yet. That's the reason I now take KPV every day, plus TA-1 2x/week, because I want to do everything possible to bring inflammation down and strengthen my anti-inflammatory response when I get sick.

Motivation is another thing that takes a hit. Once I'm at the gym I'm fine, but summoning the energy to actually get there is its own mental exertion.

And honestly, as much as I enjoy a good nap with my cat, it's rough that the moment I wake up each day, my first thought is about when I can fit in another nap later. 😹
Semax works for me, though you need 1 mg — SQ or IN — before it really takes hold. Adamax strikes me as a far better option, except that the maximum cycle is 30 days, and after two weeks my receptors have already gone dull, so I bump the dose from 350 mcg up to 500 mcg. Then what do you do during the remaining washout time? Pairing P21 with Adamax works really well, and I'll stick with that, though the cycle limits are identical.

Below I've got a link to a Modafinil guide. From what I can tell, its main action is on concentration, with a bit of a motivational boost. The schedule is 5 days on/2 days off, plus a 1 week wash out if you use it long term, and you absolutely need choline supplementation. It isn't cheap either, but I'll look into it.



View attachment 374



How to Take Modafinil Effectively | 16 Quick Tips and Tricks



Curious how to take Modafinil effectively? In the #1 GUIDE on getting the most of Modafinil, you'll find the best tips and tricks for smart drug users.

View attachment 375


www.modafinil.com

Thanks for the guide — the choline aspect was new to me, and I'll be sure to check it out.

On price, I managed to get it for fairly little. My bigger concern is a possible interaction with another medication I take, which is roughly why I only use it now and then. If I could, I'd use it daily, since it works that well for the issue I'm dealing with.
 
Back
Top