“Tirz is Tirz” What is your experience?

HouseCat

HouseCat

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I spend an inordinate amount of time on Reddit, and a common debate is whether “tirz is tirz”…some people swear by certain pharmacies, others say it’s all the same. I don’t have a horse in the race since I’ve only tried tirz from two different compounding pharmacies so far and don’t have enough anecdotal data to judge.

For the gray space, assuming your product tests at 98-99%+ purity/you can access the COAs to show it does, have you ever found a difference between your kits in how it affects you regarding efficacy, weight loss or side effects or anything else?

Enquiring minds wanna know!
 
woundcarping said:


Clearly you didn’t do a search for defective/bunk tirz.

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That’s why I specified that I am interested in experiences from people who can reasonably verify that the purity of their products was close to 100%. I’m not interested in real vs bunk, I’m interested in real vs real.
 
I actually see less variability in the grey market. All of my Tirz has a vendor COA and paid 3rd party testing. Some makes me fart more. That is about it. They all have been extremely effective. In the Telehealth market, I could absolutely tell the difference between BPI, Hallandale, ProRx, and Olympia. PH and additives/preservatives had my wife and me respond differently in terms of efficiency, side effects and weight loss. Also, it will never be 100% on any test because of the salts.
 
chewonmysac said:


I actually see less variability in the grey market. All of my Tirz has a vendor COA and paid 3rd party testing. Some makes me fart more. That is about it. They all have been extremely effective. In the Telehealth market, I could absolutely tell the difference between BPI, Hallandale, ProRx, and Olympia. PH and additives/preservatives had my wife and me respond differently in terms of efficiency, side effects and weight loss. Also, it will never be 100% on any test because of the salts.

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thanks for answering! That’s interesting about the lack of variability in gray; & given my plans going forward, great to hear!
 
Of the 3 vendor's products I've had over the last year, I can tell no difference one from another. Pep Calc app keeps them all the same strength🙂
 
byefatlicia said:


Of the 3 vendor's products I've had over the last year, I can tell no difference one from another. Pep Calc app keeps them all the same strength🙂

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Thanks for tip about Pep Calc 😊
 
I have purchased from at least 10 different gray vendors in the past two years and I have never been able to tell a difference. They were all great
 
HouseCat said:


I spend an inordinate amount of time on Reddit

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Probably worse for your physical and mental health than obesity 😂. Especially the tirzepatidecompound sub-reddit. I used to spend a lot of time there…

As far as tirz being tirz between compound pharmacies, I do think that there are some differences. Before grey, I had my favorite pharmacy. But I don’t attribute that difference to something different in the molecules, I think it was the concentration. Each pharmacy blends at various concentrations, but you really don’t know if that concentration is actually what’s in the vial. Compounded tirzepatide is rarely (if ever) tested for mass/purity, so I suspect that some pharmacies may have made their concentrations a little higher than specified. And thus , sometimes certain pharmacy’s product had more “feelz” and some were deemed “water”.

In the grey world, you can reconstitute at various concentrations and not consider any overfill in your computations, which is what I usually do. Any extra is just a bonus and more feelz. So, just say a kit of T60 vial tests at 68mg, I just ignore the 8mg. Gives each shot a little more “juice”.
 
I think there's a bit of placebo effect going on. The Tirz that arrives in a tidy box with colorful labels and slick ice packs probably "works" better than the one that arrived in a warm bubble wrap pouch with vial labels askew.

That being said, I'm sure there are cases where unreported overfill led to the impression that one brand was stronger.
 
only difference for me was my first grey purchase was a significant overfill, which gave me a stronger effect.

i am not as far along as some here, but have used vials from 3 different grey sources and all were pretty comparable.
 
I spend time on Reddit, this IS a consistent theme, but I've used compounded from multiple pharmacies, couldn't tell a bit of difference in any of them. I think folks just use it as THE thing that must explain their stall.
 
Grogu said:


Probably worse for your physical and mental health than obesity 😂. Especially the tirzepatidecompound sub-reddit.

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Haha! I feel you, and drumroll…you are correct, the last few months that’s the sub I go to most often. BUT if it hadn’t been for that, I would have never found my way here!

Grogu said:


So, just say a kit of T60 vial tests at 68mg, I just ignore the 8mg. Gives each shot a little more “juice”.

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I like this tip, thanks! I’m currently waiting for Jano to receive my vials, hoping all goes as I hope it does.
 
HouseCat said:


I like this tip, thanks! I’m currently waiting for Jano to receive my vials, hoping all goes as I hope it does.

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Good luck with your testing! Did you send these on your own or are you part of a group?
 
Grogu said:


Good luck with your testing! Did you send these on your own or are you part of a group?

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Thanks 😁 I’m testing it myself…it’s on its way to Jano now (mass/purity, endo and heavy metals)!
 
Apart from the compounded ones, there is no difference , other than slight dose variations due to underfill/overfill. The compounded ones with b12 could be weaker as there was a recent paper showing b12 and tirzepatide form complexes when mixed together, which presumably will alter its effects to some degree, almost certainly making it less effective at a given dose.
 
All of mine has been compounded OR brand name, and I can absolutely tell a difference from the brand name/no additive compounded vs the ones that are compounded with additives like glycine or b12. In fact, the ones with any B vitamin in the mix send my B vitamins up so high it is in dangerous territory, since I take a bariatric multi and it just piles onto that. I had a favorite compounder who unfortunately no longer makes GLPs (RIP Olympia!) but I still have some Hallandale as well.
 
lessthanhalf said:


Apart from the compounded ones, there is no difference , other than slight dose variations due to underfill/overfill. The compounded ones with b12 could be weaker as there was a recent paper showing b12 and tirzepatide form complexes when mixed together, which presumably will alter its effects to some degree, almost certainly making it less effective at a given dose.

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OK, so, if there is possibly 5 sources for true Tirz. API, do the legal compounders employ this API, or do they have to concoct some pseudo-api?

My relationship with compounders wasn't good. I still don't know if compounders can sell lyphilised product? But by adding strange and possibly destructive fillers, I now understand why compounders suck.
 
spanky2026 said:


I spend time on Reddit, this IS a consistent theme, but I've used compounded from multiple pharmacies, couldn't tell a bit of difference in any of them. I think folks just use it as THE thing that must explain their stall.

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Agree 100%. Having tried various compounding pharmacies I couldn’t tell any difference. Reddit is full of drama queens
 
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