The GLP4 log

TopzyTirzy

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Has it ever crossed your mind what might go down if every peptide you have got dumped into a single vial, followed by an injection of that mixture?

Your curiosity can stop now.

Say hello to: GLP4

Cagrilinitide+tirzepatide+semaglutide+retatrutide

Each one sits in its own vial, already reconstituted so that the concentration equals a second tier dose per 25mg. Take semaglutide: the starting dose is .25mg, and the second tier dose is .5mg. That means my sema vial is mixed to .5mg/25 units (this is how I handle every peptide, so a mix-up still lands me at a standard dose instead of turning me into the guy who planned on 10mg of motsc and ended up with 30mg of reta), tirz comes out to 5mg/25 units, reta matches that, and cagri is .5/25 units.

From there I drew 25 units out of each one and combined them in one vial. So the contents should be .5mg sema, .5 mg cagri, 5mg tirz, 5mg reta, spread across 100 units. Because every ingredient sits at a second tier dose per 25 units, my expectation is second tier effects from 25 units, meaning a 25 unit shot ought to give me the same suppression as .5mg of sema or 5mg tirz.

Once my alchemy was done, I pulled 10 units of it to find out whether I would drop dead or have some kind of reaction. It went terribly wrong and sadly I have died, and this is TopzyTirzys ghost writing this.

Nah so far I am doing fine. Nothing gelled up in the vial, which is the thing I always saw people predicting would happen when glp1s get mixed. I also think I'm having slight diarrhea/farts, but last week when I took cagri I had 24 hours of bad butt explosions, so i think its just due to the cagri.

In terms of appetite, its pretty suppressed today. I have however recently took so reta and cag too.

I think ill take 25 units tomorrow, ill update more.

Oh and why am I doing this? Kind of just want to see, and also I get side effects from tirz, sema, and cagri, and not enough appetite suppression from reta, so I was wondering if there is a magic middle ground where if I combine then I will feel great and not hungry.
 
I'm constantly surprised by what I read here. This whole notion makes no sense at all. Also, just so you know, cagrilintide isn't a GLP-1, so you won't be getting a GLP-4.
 
Why bother stacking when you could instead settle that age-old question: "Will it blend"?

Should you spot any lumps appearing on your back, no need for concern — those are simply your fresh angel wings coming through.
 
Fascinating. It's risky and I wouldn't suggest it, yet I'm quite curious about your experiment. Let us know how it goes.
 
TopzyTirzy said:

Has it ever crossed your mind what might go down if every peptide you have got dumped into a single vial, followed by an injection of that mixture?

Your curiosity can stop now.

Say hello to: GLP4

Cagrilinitide+tirzepatide+semaglutide+retatrutide

Each one sits in its own vial, already reconstituted so that the concentration equals a second tier dose per 25mg. Take semaglutide: the starting dose is .25mg, and the second tier dose is .5mg. That means my sema vial is mixed to .5mg/25 units (this is how I handle every peptide, so a mix-up still lands me at a standard dose instead of turning me into the guy who planned on 10mg of motsc and ended up with 30mg of reta), tirz comes out to 5mg/25 units, reta matches that, and cagri is .5/25 units.

From there I drew 25 units out of each one and combined them in one vial. So the contents should be .5mg sema, .5 mg cagri, 5mg tirz, 5mg reta, spread across 100 units. Because every ingredient sits at a second tier dose per 25 units, my expectation is second tier effects from 25 units, meaning a 25 unit shot ought to give me the same suppression as .5mg of sema or 5mg tirz.

Once my alchemy was done, I pulled 10 units of it to find out whether I would drop dead or have some kind of reaction. It went terribly wrong and sadly I have died, and this is TopzyTirzys ghost writing this.

Nah so far I am doing fine. Nothing gelled up in the vial, which is the thing I always saw people predicting would happen when glp1s get mixed. I also think I'm having slight diarrhea/farts, but last week when I took cagri I had 24 hours of bad butt explosions, so i think its just due to the cagri.

In terms of appetite, its pretty suppressed today. I have however recently took so reta and cag too.

I think ill take 25 units tomorrow, ill update more.

Oh and why am I doing this? Kind of just want to see, and also I get side effects from tirz, sema, and cagri, and not enough appetite suppression from reta, so I was wondering if there is a magic middle ground where if I combine then I will feel great and not hungry.
wait, you're being serious?
 
mraajr said:

I'm constantly surprised by what I read here. This whole notion makes no sense at all. Also, just so you know, cagrilintide isn't a GLP-1, so you won't be getting a GLP-4.





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That's what you are now.
 
Clearly, you haven't experienced what happens when you take too many GLPs. Trust me, it's awful. One moment you're dealing with gas, burping, and loose stools, and the next you're stuck in bed for 7 days, feeling worse than if you had the flu. Luckily, I doubt it's fatal, but you waste a week of your life just waiting for the GLP effects to fade. Best of luck!
 
honestly, i really can't understand the reason behind doing something like that. It just raises the chance of severe adverse reactions.
 
miss-sanne said:

honestly, i really can't understand the reason behind doing something like that. It just raises the chance of severe adverse reactions.

Heads up: possible adverse reactions involve turning into: a total smoke show
 
TopzyTirzy said:

Has it ever crossed your mind what might go down if every peptide you have got dumped into a single vial, followed by an injection of that mixture?

Your curiosity can stop now.

Say hello to: GLP4

Cagrilinitide+tirzepatide+semaglutide+retatrutide

Each one sits in its own vial, already reconstituted so that the concentration equals a second tier dose per 25mg. Take semaglutide: the starting dose is .25mg, and the second tier dose is .5mg. That means my sema vial is mixed to .5mg/25 units (this is how I handle every peptide, so a mix-up still lands me at a standard dose instead of turning me into the guy who planned on 10mg of motsc and ended up with 30mg of reta), tirz comes out to 5mg/25 units, reta matches that, and cagri is .5/25 units.

From there I drew 25 units out of each one and combined them in one vial. So the contents should be .5mg sema, .5 mg cagri, 5mg tirz, 5mg reta, spread across 100 units. Because every ingredient sits at a second tier dose per 25 units, my expectation is second tier effects from 25 units, meaning a 25 unit shot ought to give me the same suppression as .5mg of sema or 5mg tirz.

Once my alchemy was done, I pulled 10 units of it to find out whether I would drop dead or have some kind of reaction. It went terribly wrong and sadly I have died, and this is TopzyTirzys ghost writing this.

Nah so far I am doing fine. Nothing gelled up in the vial, which is the thing I always saw people predicting would happen when glp1s get mixed. I also think I'm having slight diarrhea/farts, but last week when I took cagri I had 24 hours of bad butt explosions, so i think its just due to the cagri.

In terms of appetite, its pretty suppressed today. I have however recently took so reta and cag too.

I think ill take 25 units tomorrow, ill update more.

Oh and why am I doing this? Kind of just want to see, and also I get side effects from tirz, sema, and cagri, and not enough appetite suppression from reta, so I was wondering if there is a magic middle ground where if I combine then I will feel great and not hungry.

In principle, keeping the GLPs apart—rather than combining them—should lower the chance of problems like aggregation or clumping. Each one would go into a separate spot. Yes, that means 4 shots rather than a single one, though spacing them across different days is always an option.
 
yesterday my roommate injected 10 units of the glp4, and nothing bad happened — only the positive effects.

today I went with 15 units more. appetite is under control, and I'm not feeling any downsides.

all in all 10/10, I'd repeat it. if I end up dead, I'll let you all know.

@ZippityDooDah any chance I can move up from glp1 novice to GLP4 creator?
 
What are your usual weekly doses for reta, tirz, cagri, and sema? In other words, had you already been running a heavy stack prior to this?

TopzyTirzy said:

yesterday my roommate injected 10 units of the glp4, and nothing bad happened — only the positive effects.

today I went with 15 units more. appetite is under control, and I'm not feeling any downsides.

all in all 10/10, I'd repeat it. if I end up dead, I'll let you all know.

@ZippityDooDah any chance I can move up from glp1 novice to GLP4 creator?
Would a four-peptide combo with a daring buddy be what P Diddy termed freakoffs?
 
Glenn said:

Clearly, you haven't experienced what happens when you take too many GLPs. Trust me, it's awful. One moment you're dealing with gas, burping, and loose stools, and the next you're stuck in bed for 7 days, feeling worse than if you had the flu. Luckily, I doubt it's fatal, but you waste a week of your life just waiting for the GLP effects to fade. Best of luck!
Also, while you're stuck in the hospital, you can't really make the most of the food they serve. That's the absolute worst bit.
 
Keep in mind that the effects of these peptides stick around for a very long time — weeks might pass before any side effects or impacts show up, and they could arrive gradually or all at once.

Take my advice with however many grains of salt you like. maybe this is the moment to sort out your insurance, your will and your affairs.
 
No survodutide? What about mazdutide? Liraglutide? Seriously, if this experiment is happening at all, then commit fully or don't bother!

(Just to cover myself legally, should you go through with it and end up dying a terrible GLP-caused death by your own hand, I'm not genuinely suggesting the above.)
 
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