Switching from Sema to Reta?
- Thread starter Phatmax
- Start date
My switch was from 0.75 mg of Sema to Reta, and because I quit Sema, my starting dose was 1mg/week. There wasn't much of a feeling at that level, so two weeks later I titrated up to 2 mg/week. Now I'm looking at going to 3 mg/week once four weeks have passed, to find out whether I can get some effect.
MsGizmo
Explorer
On Sunday I'd take 1mg of sema, and on Wednesday I'd take .5mg of reta. My increases were gradual, and I never raised both in the same week. Right now I'm on 1.5 mg of sema plus 8mg of reta.
Ultra_Unlimited
Explorer
When semaglutide was still a new research compound available on the free market a couple years back, 1mg of it played a key role in my losing 65-70 lbs. My Retatrutide starting dose was 1.5mg, and I moved up fast to 2.2, 3, and 4, then jumped to 8 mg.
In my view, beginning at 2-4 mg is likely the optimal approach.
In my view, beginning at 2-4 mg is likely the optimal approach.
woundcarping
Explorer
I’d begin with 1mg/day, spaced out however he prefers, to raise exposure gradually and avoid going past the target and then having to wait it out longer.
When I switched from Tirz to Reta, during week 1 I injected 7mg across 6 shots. Over my first month, that totaled 36mg given in 15 injections. I had no negative side effects.
When I switched from Tirz to Reta, during week 1 I injected 7mg across 6 shots. Over my first month, that totaled 36mg given in 15 injections. I had no negative side effects.
Blindman
Explorer
I went from 1mg in week 1, then 2mg in week 2, then 3mg in week 3 of reta. It gave me something like a head cold. I'm new, so I don't know if I just have to get used to it, but during the first 2 weeks I barely noticed anything. At 3mg it's clearly doing something: I had lunch, then dinner, 8oz bowls of tuna and eggs, and I was set for the day.
muleman750
Explorer
I moved over from 2mg sema to 3mg reta. Sema had stopped working for me. After making the change, I dropped 11lb within 2 weeks. I'm now on week 3 at 3mg reta. What stands out most is that I barely get any sides, unlike with sema. With reta, my brain signals that I'm full. With sema, I get fullness or a bit of nausea that kills my appetite. Reta definitely leaves me more irritated by other people 
Week 4 I'll increase to 4mg. Best of luck.
Week 4 I'll increase to 4mg. Best of luck.Before I made the change, I had been taking 2.4 of wagovey (Sema). When I switched, I began again at low doses. Looking back, roughly 4mg would have been the right starting point. I agree with what was said above: I would begin at 2mg.