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What's the way to tell which supplement brands are trustworthy? There's no regulation on any of them. It feels just as much like the wild wild west as peptides do.birdwhacker said:
Getting solid nutrition down to its fundamentals, in my view, means covering a few bases: a methylated B12 complex (igennus makes a solid one), a trace mineral complex (nutricost's version is decent), plus magnesium glycinate or magnesium malate. NOW foods has a reliable reputation. When it comes to glycinate, Doctor's Best gets my pick.bockscar said:
For my friend, what would you suggest he take? He hadn't considered this angle at all...but since he's committed long-term and isn't particularly old, coming across this gave him a real scare. Him, obviously—not me. I'm definitely not asking about myself.birdwhacker said:
Honestly this comes down to a skill issue. It only affects those who skip all cardiac supplements.spanky2026 said:
I remain skeptical that Reta carries no meaningful heart-related risks. In the most recent trial I looked at, arrhythmias showed up, and there were also a couple of cardiac deaths among those in the test group — yet the presenter at ADA, who was paid, dismissed this as statistically "insignificant". ?! I'm not 79, but I'm still up there in years, and heart problems like these don't strike me as 'insignificant" at all.
Just wait
SeaGypsy, are you regularly taking magnesium or potassium?SeaGypsy said:
I had the same experience — after starting Reta, my resting heart rate became erratic. Even while just sitting and watching TV, it would jump into the 140s. Since I'm in my 50's, heart issues carry real weight for me. I switched back to Tirz.spanky2026 said:
I remain skeptical that Reta carries no meaningful heart-related risks. In the most recent trial I looked at, arrhythmias showed up, and there were also a couple of cardiac deaths among those in the test group — yet the presenter at ADA, who was paid, dismissed this as statistically "insignificant". ?! I'm not 79, but I'm still up there in years, and heart problems like these don't strike me as 'insignificant" at all.
(btw I'm completely talking out of my ass)
On top of that, adding a bit of extra potassium is worth doing. Psilium husk or bananas can supply it. Plenty of drink mixes out there carry a good amount, though the price has to make sense. Alternatively, no salt from the store works fine sprinkled into food or stirred into water.
Beyond that, Ubiquinol is a worthwhile add-on, particularly for heart support. Skip the Qunol brand, and to be honest, nutricost wouldn't be my choice for that one either. These days NOW foods is close to the only option I'd feel safe with, along with life extensions and a small handful of others.
I'm going to look into that. This is news to me. Every cardiologist I work with at Orlando's largest hospital holds it in high regard. If it turns out I was fooled, I'll be furious.birdwhacker said:
Qunol has been caught faking products, most notably magnesium, along with Double Wood, Nutricost, and many other brands. See the attached image, all of the companies highlighted in red FAILED testing for the amount of magnesium glycinate that they failed to contain. When you search for supplements on Amazon, any number of the recommended brands are low quality and known for lying.
Here is the video discussing the lab results on the magnesium:
View: https://www.youtube.com/watch?v=YaQ6bpDqhuw
View: https://www.reddit.com/r/Supplements/comments/1abcfzd/what_are_some_companies_we_know_have_faked_their/
Click to expand...
The sole method to get an answer is hunting down discussions about it, and as far as public forums go, there's basically just 1.anotherusername said:
What's the way to tell which supplement brands are trustworthy? There's no regulation on any of them. It feels just as much like the wild wild west as peptides do.birdwhacker said:
Getting solid nutrition down to its fundamentals, in my view, means covering a few bases: a methylated B12 complex (igennus makes a solid one), a trace mineral complex (nutricost's version is decent), plus magnesium glycinate or magnesium malate. NOW foods has a reliable reputation. When it comes to glycinate, Doctor's Best gets my pick.bockscar said:
For my friend, what would you suggest he take? He hadn't considered this angle at all...but since he's committed long-term and isn't particularly old, coming across this gave him a real scare. Him, obviously—not me. I'm definitely not asking about myself.birdwhacker said:
Honestly this comes down to a skill issue. It only affects those who skip all cardiac supplements.spanky2026 said:
I remain skeptical that Reta carries no meaningful heart-related risks. In the most recent trial I looked at, arrhythmias showed up, and there were also a couple of cardiac deaths among those in the test group — yet the presenter at ADA, who was paid, dismissed this as statistically "insignificant". ?! I'm not 79, but I'm still up there in years, and heart problems like these don't strike me as 'insignificant" at all.
Just wait
SeaGypsy, are you regularly taking magnesium or potassium?SeaGypsy said:
I had the same experience — after starting Reta, my resting heart rate became erratic. Even while just sitting and watching TV, it would jump into the 140s. Since I'm in my 50's, heart issues carry real weight for me. I switched back to Tirz.spanky2026 said:
I remain skeptical that Reta carries no meaningful heart-related risks. In the most recent trial I looked at, arrhythmias showed up, and there were also a couple of cardiac deaths among those in the test group — yet the presenter at ADA, who was paid, dismissed this as statistically "insignificant". ?! I'm not 79, but I'm still up there in years, and heart problems like these don't strike me as 'insignificant" at all.
(btw I'm completely talking out of my ass)
On top of that, adding a bit of extra potassium is worth doing. Psilium husk or bananas can supply it. Plenty of drink mixes out there carry a good amount, though the price has to make sense. Alternatively, no salt from the store works fine sprinkled into food or stirred into water.
Beyond that, Ubiquinol is a worthwhile add-on, particularly for heart support. Skip the Qunol brand, and to be honest, nutricost wouldn't be my choice for that one either. These days NOW foods is close to the only option I'd feel safe with, along with life extensions and a small handful of others.
Even over at the prestigious shands... They're only human lol. How does the saying go, every vendor is good until they aren't?HARLEYV2 said:
I will check this out . Had no idea . All the Cardiologist I know at the Biggest Hospital in Orlando where I work swear by it . I'll pe pissed if I got duped.
Click to expand...
Hey Zippity, what forum works best for science articles? I won't bring politics into it, promise!ZippityDooDah said:
If I end up having to remove yet another post that's full of political nonsense, I'll simply begin banning users.
It looks like this compound is getting the green light, maybe since it serves to showcase how the peptide performs and its safety profile. By this point, there's a huge amount of observational data available for AI systems to analyze and turn into actionable insights.Vash said:
I’m fairly confident many of us have already paid for Reta access…
Is it true that this approach speeds up FDA approval for a new drug?spanky2026 said:
View attachment 9988
Eli Lilly gave extraordinary obesity drug access to a 79-year-old patient. Who was it?
According to STAT, an exclusive report reveals that Eli Lilly worked with the FDA so that a 79-year-old could obtain exceptional access to an experimental obesity medication via the agency's "compassionate use" pathway.
View attachment 9989
www.statnews.com
From the article, it sounds like a well-connected elderly person was granted a compassionate use exception for Reta ahead of approval? Does anyone have additional details on this? Curious.