Semax has me hooked and that worries me

[FRMN01]

Researcher6076 said:

TipsyTirzy said:

Right now I'm running a semax cycle, and I'm about to put in an order for selank too. Testosterone and tirzepatide are also part of my stack. Sure, there are folks who feel nothing from semax, but I'm clearly not in that group. It's easy to understand how someone could get hooked on something like this... I really enjoy it. Pinning itself? No thanks, I actually despise that aspect. The rush that hits my head, though, is fantastic. It reminds me of what nicotine used to do for me, the way it lands on dopamine just right. At first I was uneasy about it, but these days I catch myself looking forward to each dose. Stacked with my adderall it performs great as well. The effects seem to stretch out longer. My dose is only .5 mg, and I plan to work up to .8. My concern is that I might enjoy it more than I should, and I don't know how to handle that. Focus and mental clarity are way up. I love it. Honestly, I can't wait for the next cycle.

Nasal use is my method, and I'm a big fan as well. There's no sudden jolt—only sharper focus, clearer thinking, improved cognition. It's as if hues appear more vivid. I'm considering running a self-administered n=1 double-blind trial to rule out placebo.

That's intriguing—what's your approach for a double-blind setup? From what I gather, you'd need 2 additional individuals to make it work correctly.

 

[CNCCurrency]

FRMN01 said:

Researcher6076 said:

TipsyTirzy said:

Right now I'm running a semax cycle, and I'm about to put in an order for selank too. Testosterone and tirzepatide are also part of my stack. Sure, there are folks who feel nothing from semax, but I'm clearly not in that group. It's easy to understand how someone could get hooked on something like this... I really enjoy it. Pinning itself? No thanks, I actually despise that aspect. The rush that hits my head, though, is fantastic. It reminds me of what nicotine used to do for me, the way it lands on dopamine just right. At first I was uneasy about it, but these days I catch myself looking forward to each dose. Stacked with my adderall it performs great as well. The effects seem to stretch out longer. My dose is only .5 mg, and I plan to work up to .8. My concern is that I might enjoy it more than I should, and I don't know how to handle that. Focus and mental clarity are way up. I love it. Honestly, I can't wait for the next cycle.

Nasal use is my method, and I'm a big fan as well. There's no sudden jolt—only sharper focus, clearer thinking, improved cognition. It's as if hues appear more vivid. I'm considering running a self-administered n=1 double-blind trial to rule out placebo.

That's intriguing—what's your approach for a double-blind setup? From what I gather, you'd need 2 additional individuals to make it work correctly.

 

[Researcher6076]

FRMN01 said:

Researcher6076 said:

TipsyTirzy said:

Right now I'm running a semax cycle, and I'm about to put in an order for selank too. Testosterone and tirzepatide are also part of my stack. Sure, there are folks who feel nothing from semax, but I'm clearly not in that group. It's easy to understand how someone could get hooked on something like this... I really enjoy it. Pinning itself? No thanks, I actually despise that aspect. The rush that hits my head, though, is fantastic. It reminds me of what nicotine used to do for me, the way it lands on dopamine just right. At first I was uneasy about it, but these days I catch myself looking forward to each dose. Stacked with my adderall it performs great as well. The effects seem to stretch out longer. My dose is only .5 mg, and I plan to work up to .8. My concern is that I might enjoy it more than I should, and I don't know how to handle that. Focus and mental clarity are way up. I love it. Honestly, I can't wait for the next cycle.

Nasal use is my method, and I'm a big fan as well. There's no sudden jolt—only sharper focus, clearer thinking, improved cognition. It's as if hues appear more vivid. I'm considering running a self-administered n=1 double-blind trial to rule out placebo.

That's intriguing—what's your approach for a double-blind setup? From what I gather, you'd need 2 additional individuals to make it work correctly.

My plan is to prepare 2 nasal spray bottles that look the same. One will contain only bacteriostatic water. The other will contain bacteriostatic water plus semax. I hand both over to my partner, and I let her know which bottle holds the semax. She marks them as 1 and 2. She knows whether 1 or 2 contains the semax, but she keeps that information from me. After that, she returns them to the fridge. I'm the one who doses them, and I record what I notice from bottle 1 and from bottle 2. That way I'm blind as the subject. I'm also blind as the person administering it, since I do it myself. She has no role in giving the doses and has no idea which one I'm using at any point, so nothing she does can tip me off. When it's over, I'll have my notes, and we can check whether any differences I picked up line up with semax or not.

 

[Chili777]

Researcher6076 said:


I will make two identical nasal spray bottles, one with just the bacteriostatic water and one with bacteriostatic water and semax added. Then I give them to my partner and tell her which one has semax in it. She labels them 1 and 2. She keeps track which of 1 or 2 has the semax but doesn't tell me. Then she puts them back in the fridge. I administer them myself and keep track of effects from bottle 1 and bottle 2. So I the subject am blind. And I the administrator (self administer) am blind. She doesn't participate in the administration and doesn't know which I use, so I cannot get any hint from her. At the end I have my notes and we can see if I found any differences if those differencea match up with semax or not.

Click to expand...

Are you using BAC rather than sterile saline? BAC really dries out my sinuses. It's too much for me to tolerate.

 

[Researcher6076]

Bacteriostatic isn't an issue for me in the slightest. I also have bacteriostatic saline that came from Hosperia. I just haven't given it a go yet.

 

[FRMN01]

Researcher6076 said:


I will make two identical nasal spray bottles, one with just the bacteriostatic water and one with bacteriostatic water and semax added. Then I give them to my partner and tell her which one has semax in it. She labels them 1 and 2. She keeps track which of 1 or 2 has the semax but doesn't tell me. Then she puts them back in the fridge. I administer them myself and keep track of effects from bottle 1 and bottle 2. So I the subject am blind. And I the administrator (self administer) am blind. She doesn't participate in the administration and doesn't know which I use, so I cannot get any hint from her. At the end I have my notes and we can see if I found any differences if those differencea match up with semax or not.

Click to expand...

If the study is truly double blind, then whoever administers it must also be kept in the dark

 

[TipsyTirzy]

Chili777 said:

TipsyTirzy said:

myopicmystic said:

Is this the regular version or N-acetyl semax? I don't know how they differ, but from what I understand, N-acetyl is more stable when injected

plain semax — from what I've read, N-acetyl and adamax hit harder, and if I try those I might lose my mind lol

NA offers better bioavailability and a longer duration, yet to me it doesn't hit harder than the standard version. Adamax, by contrast, is said to be rocket fuel. I've got some on hand but haven't mixed it up yet. Once the Semax vial is finished, I'll need to choose when to use it.

Appreciate the info, I'll be sure to check it out. Today I ran a test by skipping my adderall, just to rule out whether I was tricking myself. The result: nowhere near the same "buzz," and it had mostly faded by around 4 hours. That fits with adderall amplifying the effect, especially since folks turn to semax when their adhd meds aren't available. Are the BAC dilution and the dosages identical?

 

[Heiko]

what does semax do for you?

 

[MsGizmo]

Well, I went ahead and made the purchase for my husband. He's been struggling with some forgetfulness, which is likely tied to his diabetes. If it ends up helping him, I may bring it up with my mother and ask whether she'd be open to giving it a try too. I suppose we'll find out.

 

[Neurogroot]

TipsyTirzy said:

Chili777 said:

TipsyTirzy said:

myopicmystic said:

Is this the regular version or N-acetyl semax? I don't know how they differ, but from what I understand, N-acetyl is more stable when injected

plain semax — from what I've read, N-acetyl and adamax hit harder, and if I try those I might lose my mind lol

NA offers better bioavailability and a longer duration, yet to me it doesn't hit harder than the standard version. Adamax, by contrast, is said to be rocket fuel. I've got some on hand but haven't mixed it up yet. Once the Semax vial is finished, I'll need to choose when to use it.

Appreciate the info, I'll be sure to check it out. Today I ran a test by skipping my adderall, just to rule out whether I was tricking myself. The result: nowhere near the same "buzz," and it had mostly faded by around 4 hours. That fits with adderall amplifying the effect, especially since folks turn to semax when their adhd meds aren't available. Are the BAC dilution and the dosages identical?

After going through the threads on here, my take is that what you're after is something to stack with your Adderall or give it a boost? Could be it's not packing the same punch these days, or you'd just like a bit more kick without your prescriber agreeing to raise the dose? Either way, there are routes you can take, and Semax is one of them. It gives you somewhat more of a dopamine and serotonin lift.

What about Selank — have you given it a shot? The spray didn't impress me much, but subcutaneous N-Acetyl Selank Amidate? That one I really liked. It's not a slap-in-the-face kind of effect, but when a situation pops up that would normally send me into panic and spiraling, it keeps me fairly steady, dialed in, and honestly feeling pretty good. Thanks, pretend GABA!

Setting aside my guess that you want extra horsepower for your meds, if you're set on combining Adderall with Semax…

You can make sure those dopamine-synthesizing neurons get fed with "N-Acetyl L-tyrosine", an amino acid. Mucuna Pruriens Extract is another thing you could try. Both serve as precursors to L-Dopa, and L-Dopa is a precursor to dopamine.

Plenty of other approaches exist for stacking with or complementing Adderall, ranging from genuine nootropics to other substances. The options are endless, assuming that's what you're going for.

 

[nnnnnaaaaa]

Neurogroot said:

TipsyTirzy said:

Chili777 said:

TipsyTirzy said:

myopicmystic said:

Is this the regular version or N-acetyl semax? I don't know how they differ, but from what I understand, N-acetyl is more stable when injected

plain semax — from what I've read, N-acetyl and adamax hit harder, and if I try those I might lose my mind lol

NA offers better bioavailability and a longer duration, yet to me it doesn't hit harder than the standard version. Adamax, by contrast, is said to be rocket fuel. I've got some on hand but haven't mixed it up yet. Once the Semax vial is finished, I'll need to choose when to use it.

Appreciate the info, I'll be sure to check it out. Today I ran a test by skipping my adderall, just to rule out whether I was tricking myself. The result: nowhere near the same "buzz," and it had mostly faded by around 4 hours. That fits with adderall amplifying the effect, especially since folks turn to semax when their adhd meds aren't available. Are the BAC dilution and the dosages identical?

After going through the threads on here, my take is that what you're after is something to stack with your Adderall or give it a boost? Could be it's not packing the same punch these days, or you'd just like a bit more kick without your prescriber agreeing to raise the dose? Either way, there are routes you can take, and Semax is one of them. It gives you somewhat more of a dopamine and serotonin lift.

What about Selank — have you given it a shot? The spray didn't impress me much, but subcutaneous N-Acetyl Selank Amidate? That one I really liked. It's not a slap-in-the-face kind of effect, but when a situation pops up that would normally send me into panic and spiraling, it keeps me fairly steady, dialed in, and honestly feeling pretty good. Thanks, pretend GABA!

Setting aside my guess that you want extra horsepower for your meds, if you're set on combining Adderall with Semax…

You can make sure those dopamine-synthesizing neurons get fed with "N-Acetyl L-tyrosine", an amino acid. Mucuna Pruriens Extract is another thing you could try. Both serve as precursors to L-Dopa, and L-Dopa is a precursor to dopamine.

Plenty of other approaches exist for stacking with or complementing Adderall, ranging from genuine nootropics to other substances. The options are endless, assuming that's what you're going for.

When it comes to n-a selank, I like it quite a bit. As for semax, it leaves me dealing with mild aphasia -- is anyone else running into that?

 

[nnnnnaaaaa]

One more thing I want to put out there: any idea what could be behind brain fog, mild aphasia, and similar issues while using semax? Instead of the sharper thinking a lot of you describe, I'm getting the reverse.

 

[Rink123]

Researcher6076 said:


I will make two identical nasal spray bottles, one with just the bacteriostatic water and one with bacteriostatic water and semax added. Then I give them to my partner and tell her which one has semax in it. She labels them 1 and 2. She keeps track which of 1 or 2 has the semax but doesn't tell me. Then she puts them back in the fridge. I administer them myself and keep track of effects from bottle 1 and bottle 2. So I the subject am blind. And I the administrator (self administer) am blind. She doesn't participate in the administration and doesn't know which I use, so I cannot get any hint from her. At the end I have my notes and we can see if I found any differences if those differencea match up with semax or not.

Click to expand...

Please post an update in this thread

 

[Rink123]

I mean genuinely fascinated — I'm not trying to pressure anyone.

 

[lakelife13]

I've only been taking .5mg for 2 days now, and I haven't noticed any changes yet. How much time passed before you started noticing results?

 

[nnnnnaaaaa]

lakelife13 said:

I've only been taking .5mg for 2 days now, and I haven't noticed any changes yet. How much time passed before you started noticing results?

For me it hit right away, at a dose close to what you're using, sprayed through the nose. Either your product is fake, or I just respond strongly to it.

 

[Chili777]

lakelife13 said:

I've only been taking .5mg for 2 days now, and I haven't noticed any changes yet. How much time passed before you started noticing results?

With SQ, the usual requirement is a larger amount, since the liver screens it out prior to reaching the BBB.

 

[lakelife13]

Chili777 said:

lakelife13 said:

I've only been taking .5mg for 2 days now, and I haven't noticed any changes yet. How much time passed before you started noticing results?

With SQ, the usual requirement is a larger amount, since the liver screens it out prior to reaching the BBB.

What's the higher amount we're talking about? 1mg?

 

[Chili777]

lakelife13 said:

Chili777 said:

lakelife13 said:

I've only been taking .5mg for 2 days now, and I haven't noticed any changes yet. How much time passed before you started noticing results?

With SQ, the usual requirement is a larger amount, since the liver screens it out prior to reaching the BBB.

What's the higher amount we're talking about? 1mg?

When you inject subcutaneously, that dose ought to be sufficient for a reaction. Still, not everyone experiences one. My own SQ dose is 1 mg. Others push it further, yet I haven't felt the need to.

 

[lakelife13]

Chili777 said:

lakelife13 said:

Chili777 said:

lakelife13 said:

I've only been taking .5mg for 2 days now, and I haven't noticed any changes yet. How much time passed before you started noticing results?

With SQ, the usual requirement is a larger amount, since the liver screens it out prior to reaching the BBB.

What's the higher amount we're talking about? 1mg?

When you inject subcutaneously, that dose ought to be sufficient for a reaction. Still, not everyone experiences one. My own SQ dose is 1 mg. Others push it further, yet I haven't felt the need to.

SQ is what I'm using too. When week 2 rolls around, I might bump the dose up slightly.