[Progress][NSFW] 12 Months on GLP1's Plus Weight Training, Down About 30kg

Itankstuff

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My weight loss journey began in 2025. At that point I was depressed and anxious, and had just been put on antidepressants for the first time. Lexapro came first, and Bupropion was added later. On top of that, I had recently received a diagnosis of obstructive sleep apnoea. Fatigue and lethargy dominated my days, and if I'm honest, I was simply watching life go by without participating in it.

I'm in my early 30's. Back in my college years I had been a fairly fit guy. My first year of college, at about age 17, is when I began lifting weights. It wasn't a consistent or frequent habit, maybe 2-3 times a week. Still, the noob gains were real; muscle seemed to come on fairly quickly for me, and I found the gym to be an excellent tool for my mental health. Looking back, it's so hard to understand how I had fallen so hard and ended up at my heaviest recorded weight (I stopped weighing myself out of embarassment, I'm sure some of you can relate) sitting at around 131-132kg, my height is 185.5cm.

Feeling so empty and depressed, while also managing a very stressful job, led me to "reward" myself with wine. Friday and Saturday nights became my reward for decompressing. Wine felt classy, or so I thought. But there was nothing classy when over the course of 4 years the Friday and Saturday nights were accompanied by the Monday night bottle of wine "because it was a stressful day", then the Wednesday drinking session to "get through the mid week".... I'm sure you get the picture. By the end of it I have to estimate I would probably have 10-15 standard drinks of alcohol 3-4 nights a week (a standard drink being 10g of alcohol).

Image 1: March/April 2025





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Weighing around 131-132kg. Highest recorded.

For a long time I resisted GLP1’s, having read extensively about the side effects. Pancreatitis or gastroparesis were things I feared. I feared dropping weight too fast and being left with too much loose skin. All sorts of excuses were made. Eventually I reached a point where it felt like my way of living would put me in an early grave. So do you know what my rationale was for starting Tirzepatide? “Well, I’m going to die anyways, so why does it matter if it’s the Tirze that kills me”. It’s sad reflecting back on that mentality, but in many ways it kickstarted this whole journey. This realisation came to me in Jan/Feb, but looking at my Shotsy data, it turns out I didn’t muster the courage to start until April. Speaking to my Doctor was too embarrassing, since our initial conversation was met with, “well, why don’t you just try doing it the normal way first.” I had explained that I had lost weight before and had been, up until this point, a regular gym goer. Macros, calories, fasting, you name it — I understood them. But I didn’t understand how to do it with this black cloud hanging over me. After that experience I signed up to an online clinic. A phone call with a lovely Nurse Practitioner followed, and for the first time she made me feel that I could maybe, just maybe, take control back of my life.

Image 2: The GLP1 Journey via Shotsy

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For those of you wondering what happened in January this year, don't worry, I can explain....

And so off I went, I started Tirzepatide, or Mounjaro as it's called around these parts. It was amazing. It was strange, I couldn't describe the feeling, but I just didn't thnk about food. It was weird, I didn't think or desire alcohol either. I mean, I still drank, because it was habit. The alcohol tasted funny, I enjoyed wine and I loved my gin and tonic, but they tasted funny. Despite this, I continued to drink, because I never thought I would never not drink, it's just what I did on a Friday. Without trying, it went down to 5 standard drinks 3-4 times a week. Sometimes I'd add a little chaos in to my life and thoroughly indulge myself when I could feel the Tirze wearing off, and let me tell you, I felt it the next morning. They say insanity is doing the same thing over and over again and expecting different results. I knew I was a little insane to begin with so it made sense for me to keep drinking despite not enjoying the taste, nor the feeling anymore.

By this time it was July, the 25th of July was a Friday, so you know what I did, Saturday was no different. I decided though on the 27th of July, why not continue the insanity for another day? It was on this day of insanity I said to my now fiance "I think I'm going to stop drinking next month" the expression on her face esentially read as "Oh, I'm sure you will, like the 15 other times you've said that." That expression sat with me. It may come as a surprise, but because July 27th was a Sunday, July 28th ended up being a Monday. On this auspicious Monday I poured out all the alcohol I had at home. I self excluded myself from Uber Eats and Doordash so I couldn't spontaneously order alcohol.

July 27th 2026 was the last time I had alcohol, hopefully for the rest of my life. At the time of writing this, my app says it’s been 7 months, 25 days and counting. I’ll be honest, I had tried plenty of “Sober Octobers” and “Dry Julys” before. But in all that time since quitting, there has only been a single moment where I had a genuine craving for alcohol.

For this to make sense, you have to understand that I’m on the spectrum and was recently diagnosed with ADHD, so I tend to become obsessed with obscure things. At that point in my life, it was North Korea. I was in bed watching this video on YouTube. It's essentially a video of a North Korean soldier describing how he used to dream of drinking whiskey, because it was something only royalty had access to. Watching him savour this cheap, bottom-shelf American whiskey, I suddenly wanted nothing more than to share a glass with him. Thankfully, my North Korea obsession has since taken a backseat, and for now, my sobriety is safe.

In a long-winded way, what I’m trying to say is that GLP1’s made it easy for me to abstain. It’s actually pretty funny looking at the Shotsy graph, because you can clearly see when I stopped alcohol, my sugar cravings briefly took over, and then the rapid weight loss followed. I’m starting to think the conspiracy theory that booze might be empty calories has some truth to it.

Anyways.... Mounjaro.... Not only did it make me not desire alcohol, a lot of dopamine seeking behviours reduced. I had been doing a lot of research and reading the literature and it turns out we don't quite understand the mechanism, but there's emerging evidence that the medication can help with ADHD. It all clicked. So, the alcohol, the binge eating, the risky behviours, the impulsivity... They aren't just weird quirks, but rather my dopamine starved brain looking for stimulation. I was diagnosed with ADHD, I now take Vyvanse and without a word of a lie, it's almost like I have been living life in black and white this entire time and now put on some colour vision glasses. Since starting I had reduced anxiety (though not zero, more on that later), reduced depression and I found it a bit easier to socialise. I used to get cripping social anxiety, but it was now tolerable.

Life was good. Work was good. I was going to the gym. I was trying to eat 200g of protein a day but usually hitting around 150g due to Mounjaro, but I was happy with how things progressed. I went for an overseas holiday in December, and because I wasn't working, rather than doing the normal things people do on a holiday, I read. I read and read and read, I educated myself. I spent about a month everyday reading more about peptides and peptide therapy, I read a lot about testosterone replacement therapy too. What prompted me to do so was though I felt really good, I noticed I wasn't holding on to my muscle like I used to. I had lost weight before, but this time was different. I felt flat, soft and weak. The gym was starting to become a struggle and.... I had noticed my balls started to shrink.

Image 3: January 2026. Before I went all in.

f5f1493a0392869abe45d159b79d68eb81a76d5f5e958b6b09678e0a5c81d997.webp


Recently returned from my overseas trip and ready to execute on the knowledge I had acquired.

So the cool thing about this whole reflection on the journey thing is that I get to look at photos, timestamps and dates. January 3rd is apparently the date I signed up to this forum. I think I was still overseas then but returned home shortly. I started CJC 1295/Ipamorealin and Retatrutide sometime in mid January. I'll post the January Pre Peptide photo and a photo taken in the last few days side by side as I think the effects speak for themselves. I was afraid of TRT, even though my balls were shrinking, I was scared to take TRT because I didn't want my balls to shrink (do you see a pattern here?). But because Tirze, CJC/IPA and Reta had already given me confidence in making these changes I just did it. I'm now taking TRT at around 150-175mg per week. I am still playing around with the dosages to try "dial in" my dose, but it's been 6-8 weeks on TRT so far and remember how I said treating my ADHD made me have almost no anxiety and depression? Well, it turns out having small balls and lower testosterone tends to do this, with TRT I feel like it was the missing piece of the puzzle. I still am trying to stabilise the dosage so there are some ups and downs, but I feel like I am very close to there. I feel fantastic 90% of the time.

Image 4: Before an after CJC/IPA for around 10-12 weeks and TRT for 6 weeks.

f3fe26951bba481b72d240df9ead9a517e6b29249a98ecd88cd2de660a761cde.webp


Image 5: DEXA Scan Results before and after CJC/IPA for around 10-12 weeks and TRT for 6 weeks.

73b6c501b75e8527a9d2a755626b2f64b4fe650a110b3a6fd83a32b5bcb25914.webp
 
The site's admins set a cap of 10,000 characters, which is why my summary got chopped off....

Summary

And so, here we are on the 24th of March 2026. It has now been 1 month since I stopped taking Lexapro and Bupropion. Depression isn't present, anxiety isn't present, and I have no desire for alcohol nor do I care about it. My weight has fallen to roughly 105kg, and I hope to shed another 10kg gradually, spread out across many months, without any hurry. It feels as though my entire life shifted thanks to a small (or lengthy) chain of amino acids, which set off a domino effect that led me to finally look after myself. This isn't solely about dropping weight, nor solely about squeezing into those jeans we've always dreamed of wearing. It isn't solely about feeling at ease in our own skin either. It's that this medication, and these medications as a whole, are instruments that at last give us the ability to direct our own lives, in a world and society that sometimes leaves us feeling completely powerless. The strange twist in this whole journey is that now I neither think about dying nor wish for it, so given how I feel today, I doubt I would have pushed that tiny needle into my belly to begin this path. And as a harsh irony, my balls remain small, but for the moment, I believe I'm fine with that..... Unless a peptide for it happens to be something you know about.

Thanks for reading!
 
Nice work. Your difficulties are something others share too. HCG — available through numerous peptide sellers in China — can be used to support your balls and also generate a bit of testosterone, in case you weren't aware. It signals your body to get the testicles working, which stops atrophy.
 
nice work! seems like a real health journey, and it always makes me glad when folks are more content with their lives. keep it up, dude.
 
Itankstuff said:

My weight loss journey began in 2025. At that point I was depressed and anxious, and had just been put on antidepressants for the first time. Lexapro came first, and Bupropion was added later. On top of that, I had recently received a diagnosis of obstructive sleep apnoea. Fatigue and lethargy dominated my days, and if I'm honest, I was simply watching life go by without participating in it.

I'm in my early 30's. Back in my college years I had been a fairly fit guy. My first year of college, at about age 17, is when I began lifting weights. It wasn't a consistent or frequent habit, maybe 2-3 times a week. Still, the noob gains were real; muscle seemed to come on fairly quickly for me, and I found the gym to be an excellent tool for my mental health. Looking back, it's so hard to understand how I had fallen so hard and ended up at my heaviest recorded weight (I stopped weighing myself out of embarassment, I'm sure some of you can relate) sitting at around 131-132kg, my height is 185.5cm.

Feeling so empty and depressed, while also managing a very stressful job, led me to "reward" myself with wine. Friday and Saturday nights became my reward for decompressing. Wine felt classy, or so I thought. But there was nothing classy when over the course of 4 years the Friday and Saturday nights were accompanied by the Monday night bottle of wine "because it was a stressful day", then the Wednesday drinking session to "get through the mid week".... I'm sure you get the picture. By the end of it I have to estimate I would probably have 10-15 standard drinks of alcohol 3-4 nights a week (a standard drink being 10g of alcohol).

Image 1: March/April 2025





View attachment 11211

Weighing around 131-132kg. Highest recorded.

For a long time I resisted GLP1’s, having read extensively about the side effects. Pancreatitis or gastroparesis were things I feared. I feared dropping weight too fast and being left with too much loose skin. All sorts of excuses were made. Eventually I reached a point where it felt like my way of living would put me in an early grave. So do you know what my rationale was for starting Tirzepatide? “Well, I’m going to die anyways, so why does it matter if it’s the Tirze that kills me”. It’s sad reflecting back on that mentality, but in many ways it kickstarted this whole journey. This realisation came to me in Jan/Feb, but looking at my Shotsy data, it turns out I didn’t muster the courage to start until April. Speaking to my Doctor was too embarrassing, since our initial conversation was met with, “well, why don’t you just try doing it the normal way first.” I had explained that I had lost weight before and had been, up until this point, a regular gym goer. Macros, calories, fasting, you name it — I understood them. But I didn’t understand how to do it with this black cloud hanging over me. After that experience I signed up to an online clinic. A phone call with a lovely Nurse Practitioner followed, and for the first time she made me feel that I could maybe, just maybe, take control back of my life.

Image 2: The GLP1 Journey via Shotsy

View attachment 11212

For those of you wondering what happened in January this year, don't worry, I can explain....

And so off I went, I started Tirzepatide, or Mounjaro as it's called around these parts. It was amazing. It was strange, I couldn't describe the feeling, but I just didn't thnk about food. It was weird, I didn't think or desire alcohol either. I mean, I still drank, because it was habit. The alcohol tasted funny, I enjoyed wine and I loved my gin and tonic, but they tasted funny. Despite this, I continued to drink, because I never thought I would never not drink, it's just what I did on a Friday. Without trying, it went down to 5 standard drinks 3-4 times a week. Sometimes I'd add a little chaos in to my life and thoroughly indulge myself when I could feel the Tirze wearing off, and let me tell you, I felt it the next morning. They say insanity is doing the same thing over and over again and expecting different results. I knew I was a little insane to begin with so it made sense for me to keep drinking despite not enjoying the taste, nor the feeling anymore.

By this time it was July, the 25th of July was a Friday, so you know what I did, Saturday was no different. I decided though on the 27th of July, why not continue the insanity for another day? It was on this day of insanity I said to my now fiance "I think I'm going to stop drinking next month" the expression on her face esentially read as "Oh, I'm sure you will, like the 15 other times you've said that." That expression sat with me. It may come as a surprise, but because July 27th was a Sunday, July 28th ended up being a Monday. On this auspicious Monday I poured out all the alcohol I had at home. I self excluded myself from Uber Eats and Doordash so I couldn't spontaneously order alcohol.

July 27th 2026 was the last time I had alcohol, hopefully for the rest of my life. At the time of writing this, my app says it’s been 7 months, 25 days and counting. I’ll be honest, I had tried plenty of “Sober Octobers” and “Dry Julys” before. But in all that time since quitting, there has only been a single moment where I had a genuine craving for alcohol.

For this to make sense, you have to understand that I’m on the spectrum and was recently diagnosed with ADHD, so I tend to become obsessed with obscure things. At that point in my life, it was North Korea. I was in bed watching this video on YouTube. It's essentially a video of a North Korean soldier describing how he used to dream of drinking whiskey, because it was something only royalty had access to. Watching him savour this cheap, bottom-shelf American whiskey, I suddenly wanted nothing more than to share a glass with him. Thankfully, my North Korea obsession has since taken a backseat, and for now, my sobriety is safe.

In a long-winded way, what I’m trying to say is that GLP1’s made it easy for me to abstain. It’s actually pretty funny looking at the Shotsy graph, because you can clearly see when I stopped alcohol, my sugar cravings briefly took over, and then the rapid weight loss followed. I’m starting to think the conspiracy theory that booze might be empty calories has some truth to it.

Anyways.... Mounjaro.... Not only did it make me not desire alcohol, a lot of dopamine seeking behviours reduced. I had been doing a lot of research and reading the literature and it turns out we don't quite understand the mechanism, but there's emerging evidence that the medication can help with ADHD. It all clicked. So, the alcohol, the binge eating, the risky behviours, the impulsivity... They aren't just weird quirks, but rather my dopamine starved brain looking for stimulation. I was diagnosed with ADHD, I now take Vyvanse and without a word of a lie, it's almost like I have been living life in black and white this entire time and now put on some colour vision glasses. Since starting I had reduced anxiety (though not zero, more on that later), reduced depression and I found it a bit easier to socialise. I used to get cripping social anxiety, but it was now tolerable.

Life was good. Work was good. I was going to the gym. I was trying to eat 200g of protein a day but usually hitting around 150g due to Mounjaro, but I was happy with how things progressed. I went for an overseas holiday in December, and because I wasn't working, rather than doing the normal things people do on a holiday, I read. I read and read and read, I educated myself. I spent about a month everyday reading more about peptides and peptide therapy, I read a lot about testosterone replacement therapy too. What prompted me to do so was though I felt really good, I noticed I wasn't holding on to my muscle like I used to. I had lost weight before, but this time was different. I felt flat, soft and weak. The gym was starting to become a struggle and.... I had noticed my balls started to shrink.

Image 3: January 2026. Before I went all in.

View attachment 11213

Recently returned from my overseas trip and ready to execute on the knowledge I had acquired.

So the cool thing about this whole reflection on the journey thing is that I get to look at photos, timestamps and dates. January 3rd is apparently the date I signed up to this forum. I think I was still overseas then but returned home shortly. I started CJC 1295/Ipamorealin and Retatrutide sometime in mid January. I'll post the January Pre Peptide photo and a photo taken in the last few days side by side as I think the effects speak for themselves. I was afraid of TRT, even though my balls were shrinking, I was scared to take TRT because I didn't want my balls to shrink (do you see a pattern here?). But because Tirze, CJC/IPA and Reta had already given me confidence in making these changes I just did it. I'm now taking TRT at around 150-175mg per week. I am still playing around with the dosages to try "dial in" my dose, but it's been 6-8 weeks on TRT so far and remember how I said treating my ADHD made me have almost no anxiety and depression? Well, it turns out having small balls and lower testosterone tends to do this, with TRT I feel like it was the missing piece of the puzzle. I still am trying to stabilise the dosage so there are some ups and downs, but I feel like I am very close to there. I feel fantastic 90% of the time.

Image 4: Before an after CJC/IPA for around 10-12 weeks and TRT for 6 weeks.

View attachment 11214

Image 5: DEXA Scan Results before and after CJC/IPA for around 10-12 weeks and TRT for 6 weeks.

View attachment 11215
 
MFGamesta said:

Nice work. Your difficulties are something others share too. HCG — available through numerous peptide sellers in China — can be used to support your balls and also generate a bit of testosterone, in case you weren't aware. It signals your body to get the testicles working, which stops atrophy.

ADHD and weight problems tend to be linked, so it wouldn't shock me if a fair number of people on this forum are neurodivergent in some way! Appreciate the suggestion. I do have HCG on hand and used it at the start; oddly it didn't seem to do much for the little guys, but I believe it did push my E2 up, which makes dialing in my TRT dose trickier. So for roughly the next 3 months I'm thinking of dropping it or taking a lot less. Case in point: I got only 4.5 hours of sleep last night since yesterday was my TRT pinning day.

Volkswagen57 said:

Curious about your cjc ipa protocol

My dose was 250mcg/250mcg, taken twice daily — at bedtime and right after waking — and I kept fasting until midday. 4 weeks later I had my IGF checked and it came back at 405 (82-243 ng/mL). I don't recall the Z-score, but in my view it was too high. I've already got a neanderbrow and large hands, so I don't want to invite any more acromegaly-like traits haha! These days I'm on 200mcg/200mcg before bed and I'm waiting on the newest IGF1 result, which should arrive sometime today.
 
Itankstuff said:

MFGamesta said:

Nice work. Your difficulties are something others share too. HCG — available through numerous peptide sellers in China — can be used to support your balls and also generate a bit of testosterone, in case you weren't aware. It signals your body to get the testicles working, which stops atrophy.

ADHD and weight problems tend to be linked, so it wouldn't shock me if a fair number of people on this forum are neurodivergent in some way! Appreciate the suggestion. I do have HCG on hand and used it at the start; oddly it didn't seem to do much for the little guys, but I believe it did push my E2 up, which makes dialing in my TRT dose trickier. So for roughly the next 3 months I'm thinking of dropping it or taking a lot less. Case in point: I got only 4.5 hours of sleep last night since yesterday was my TRT pinning day.

Volkswagen57 said:

Curious about your cjc ipa protocol

My dose was 250mcg/250mcg, taken twice daily — at bedtime and right after waking — and I kept fasting until midday. 4 weeks later I had my IGF checked and it came back at 405 (82-243 ng/mL). I don't recall the Z-score, but in my view it was too high. I've already got a neanderbrow and large hands, so I don't want to invite any more acromegaly-like traits haha! These days I'm on 200mcg/200mcg before bed and I'm waiting on the newest IGF1 result, which should arrive sometime today.
Haha, I appreciate you getting back to me. I regret not getting my levels checked before I began (250mcg/250mcg) once nightly. However, I was just 3 weeks in when I went ahead and got my blood drawn. Still waiting on those results
 
Volkswagen57 said:

Itankstuff said:

MFGamesta said:

Nice work. Your difficulties are something others share too. HCG — available through numerous peptide sellers in China — can be used to support your balls and also generate a bit of testosterone, in case you weren't aware. It signals your body to get the testicles working, which stops atrophy.

ADHD and weight problems tend to be linked, so it wouldn't shock me if a fair number of people on this forum are neurodivergent in some way! Appreciate the suggestion. I do have HCG on hand and used it at the start; oddly it didn't seem to do much for the little guys, but I believe it did push my E2 up, which makes dialing in my TRT dose trickier. So for roughly the next 3 months I'm thinking of dropping it or taking a lot less. Case in point: I got only 4.5 hours of sleep last night since yesterday was my TRT pinning day.

Volkswagen57 said:

Curious about your cjc ipa protocol

My dose was 250mcg/250mcg, taken twice daily — at bedtime and right after waking — and I kept fasting until midday. 4 weeks later I had my IGF checked and it came back at 405 (82-243 ng/mL). I don't recall the Z-score, but in my view it was too high. I've already got a neanderbrow and large hands, so I don't want to invite any more acromegaly-like traits haha! These days I'm on 200mcg/200mcg before bed and I'm waiting on the newest IGF1 result, which should arrive sometime today.
Haha, I appreciate you getting back to me. I regret not getting my levels checked before I began (250mcg/250mcg) once nightly. However, I was just 3 weeks in when I went ahead and got my blood drawn. Still waiting on those results

Please let me know how it goes. My second round of results just came in. When I went from 250/250mcg twice daily down to once daily, here's what changed:

Serum IGF1: 405 ng/mL

Became

Serum IGF1: 314 ng/mL

The reference range is roughly (~84–245 ng/mL)

I had ChatGPT look over the assay data and lab reference ranges that were available, so it could estimate a Z score. From what it says, my latest Z score sits at 3.5 - 3.8! While the earlier one was around 5.9!

How accurate those ChatGPT calculations really are, I can't say, and I do wish the lab would publish the data.

My thinking is to target 3, so I might even divide the dose into 100/100mcg taken twice a day.
 
Itankstuff said:

Volkswagen57 said:

Itankstuff said:

MFGamesta said:

Nice work. Your difficulties are something others share too. HCG — available through numerous peptide sellers in China — can be used to support your balls and also generate a bit of testosterone, in case you weren't aware. It signals your body to get the testicles working, which stops atrophy.

ADHD and weight problems tend to be linked, so it wouldn't shock me if a fair number of people on this forum are neurodivergent in some way! Appreciate the suggestion. I do have HCG on hand and used it at the start; oddly it didn't seem to do much for the little guys, but I believe it did push my E2 up, which makes dialing in my TRT dose trickier. So for roughly the next 3 months I'm thinking of dropping it or taking a lot less. Case in point: I got only 4.5 hours of sleep last night since yesterday was my TRT pinning day.

Volkswagen57 said:

Curious about your cjc ipa protocol

My dose was 250mcg/250mcg, taken twice daily — at bedtime and right after waking — and I kept fasting until midday. 4 weeks later I had my IGF checked and it came back at 405 (82-243 ng/mL). I don't recall the Z-score, but in my view it was too high. I've already got a neanderbrow and large hands, so I don't want to invite any more acromegaly-like traits haha! These days I'm on 200mcg/200mcg before bed and I'm waiting on the newest IGF1 result, which should arrive sometime today.
Haha, I appreciate you getting back to me. I regret not getting my levels checked before I began (250mcg/250mcg) once nightly. However, I was just 3 weeks in when I went ahead and got my blood drawn. Still waiting on those results

Please let me know how it goes. My second round of results just came in. When I went from 250/250mcg twice daily down to once daily, here's what changed:

Serum IGF1: 405 ng/mL

Became

Serum IGF1: 314 ng/mL

The reference range is roughly (~84–245 ng/mL)

I had ChatGPT look over the assay data and lab reference ranges that were available, so it could estimate a Z score. From what it says, my latest Z score sits at 3.5 - 3.8! While the earlier one was around 5.9!

How accurate those ChatGPT calculations really are, I can't say, and I do wish the lab would publish the data.

My thinking is to target 3, so I might even divide the dose into 100/100mcg taken twice a day.
I'll definitely share my igf-1 result once I have it. Thanks for posting your data and results. If anyone wants them, I'll also post my total and free test levels along with estradiol. Right now I'm on 125mg test cyp 2x/ week. The dose likely needs to come down, though my blood work will reveal what's actually going on.
 
Volkswagen57 said:

Itankstuff said:

Volkswagen57 said:

Itankstuff said:

MFGamesta said:

Nice work. Your difficulties are something others share too. HCG — available through numerous peptide sellers in China — can be used to support your balls and also generate a bit of testosterone, in case you weren't aware. It signals your body to get the testicles working, which stops atrophy.

ADHD and weight problems tend to be linked, so it wouldn't shock me if a fair number of people on this forum are neurodivergent in some way! Appreciate the suggestion. I do have HCG on hand and used it at the start; oddly it didn't seem to do much for the little guys, but I believe it did push my E2 up, which makes dialing in my TRT dose trickier. So for roughly the next 3 months I'm thinking of dropping it or taking a lot less. Case in point: I got only 4.5 hours of sleep last night since yesterday was my TRT pinning day.

Volkswagen57 said:

Curious about your cjc ipa protocol

My dose was 250mcg/250mcg, taken twice daily — at bedtime and right after waking — and I kept fasting until midday. 4 weeks later I had my IGF checked and it came back at 405 (82-243 ng/mL). I don't recall the Z-score, but in my view it was too high. I've already got a neanderbrow and large hands, so I don't want to invite any more acromegaly-like traits haha! These days I'm on 200mcg/200mcg before bed and I'm waiting on the newest IGF1 result, which should arrive sometime today.
Haha, I appreciate you getting back to me. I regret not getting my levels checked before I began (250mcg/250mcg) once nightly. However, I was just 3 weeks in when I went ahead and got my blood drawn. Still waiting on those results

Please let me know how it goes. My second round of results just came in. When I went from 250/250mcg twice daily down to once daily, here's what changed:

Serum IGF1: 405 ng/mL

Became

Serum IGF1: 314 ng/mL

The reference range is roughly (~84–245 ng/mL)

I had ChatGPT look over the assay data and lab reference ranges that were available, so it could estimate a Z score. From what it says, my latest Z score sits at 3.5 - 3.8! While the earlier one was around 5.9!

How accurate those ChatGPT calculations really are, I can't say, and I do wish the lab would publish the data.

My thinking is to target 3, so I might even divide the dose into 100/100mcg taken twice a day.
I'll definitely share my igf-1 result once I have it. Thanks for posting your data and results. If anyone wants them, I'll also post my total and free test levels along with estradiol. Right now I'm on 125mg test cyp 2x/ week. The dose likely needs to come down, though my blood work will reveal what's actually going on.

On this dose, what's your experience? Even without labs, I'd like to hear about mood, libido and overall wellbeing.

The changes from TRT are unbelievable to me. Public speaking, meeting new people, work stress — all of it feels so manageable now. I'm better at letting the small stuff roll off and not stressing as much.

My job is extremely toxic, and I actually told my boss: “I’m taking 4 weeks off, I need a break. These are the dates and we can discuss the terms I want to return on.” Normally he'd push back or make excuses because I was the one asking. This time, though, I told him instead of asking, and I stayed calm, confident and clear — I could tell he respected that I held my ground.

I place more value on myself, and I can see the value I bring much more easily instead of second-guessing myself.

Philosophically, it makes me kind of get why TRT is so looked down on in society. When people don't have self-confidence and don't value themselves, they tend to be far more compliant and easily shaped.
 
Itankstuff said:

Volkswagen57 said:

Itankstuff said:

Volkswagen57 said:

Itankstuff said:

MFGamesta said:

Nice work. Your difficulties are something others share too. HCG — available through numerous peptide sellers in China — can be used to support your balls and also generate a bit of testosterone, in case you weren't aware. It signals your body to get the testicles working, which stops atrophy.

ADHD and weight problems tend to be linked, so it wouldn't shock me if a fair number of people on this forum are neurodivergent in some way! Appreciate the suggestion. I do have HCG on hand and used it at the start; oddly it didn't seem to do much for the little guys, but I believe it did push my E2 up, which makes dialing in my TRT dose trickier. So for roughly the next 3 months I'm thinking of dropping it or taking a lot less. Case in point: I got only 4.5 hours of sleep last night since yesterday was my TRT pinning day.

Volkswagen57 said:

Curious about your cjc ipa protocol

My dose was 250mcg/250mcg, taken twice daily — at bedtime and right after waking — and I kept fasting until midday. 4 weeks later I had my IGF checked and it came back at 405 (82-243 ng/mL). I don't recall the Z-score, but in my view it was too high. I've already got a neanderbrow and large hands, so I don't want to invite any more acromegaly-like traits haha! These days I'm on 200mcg/200mcg before bed and I'm waiting on the newest IGF1 result, which should arrive sometime today.
Haha, I appreciate you getting back to me. I regret not getting my levels checked before I began (250mcg/250mcg) once nightly. However, I was just 3 weeks in when I went ahead and got my blood drawn. Still waiting on those results

Please let me know how it goes. My second round of results just came in. When I went from 250/250mcg twice daily down to once daily, here's what changed:

Serum IGF1: 405 ng/mL

Became

Serum IGF1: 314 ng/mL

The reference range is roughly (~84–245 ng/mL)

I had ChatGPT look over the assay data and lab reference ranges that were available, so it could estimate a Z score. From what it says, my latest Z score sits at 3.5 - 3.8! While the earlier one was around 5.9!

How accurate those ChatGPT calculations really are, I can't say, and I do wish the lab would publish the data.

My thinking is to target 3, so I might even divide the dose into 100/100mcg taken twice a day.
I'll definitely share my igf-1 result once I have it. Thanks for posting your data and results. If anyone wants them, I'll also post my total and free test levels along with estradiol. Right now I'm on 125mg test cyp 2x/ week. The dose likely needs to come down, though my blood work will reveal what's actually going on.

On this dose, what's your experience? Even without labs, I'd like to hear about mood, libido and overall wellbeing.

The changes from TRT are unbelievable to me. Public speaking, meeting new people, work stress — all of it feels so manageable now. I'm better at letting the small stuff roll off and not stressing as much.

My job is extremely toxic, and I actually told my boss: “I’m taking 4 weeks off, I need a break. These are the dates and we can discuss the terms I want to return on.” Normally he'd push back or make excuses because I was the one asking. This time, though, I told him instead of asking, and I stayed calm, confident and clear — I could tell he respected that I held my ground.

I place more value on myself, and I can see the value I bring much more easily instead of second-guessing myself.

Philosophically, it makes me kind of get why TRT is so looked down on in society. When people don't have self-confidence and don't value themselves, they tend to be far more compliant and easily shaped.

"Feels report": I'm doing great. Before this, I dealt with depression, anxiety, and a constant sense of sluggishness and fatigue throughout the day, plus I never woke up feeling refreshed regardless of how many hours I slept.

I had been taking ssri medication for depression, which did help, but I still felt "without purpose". I also had no drive to do the things I used to enjoy.

These days, 7-8 hours of sleep leaves me feeling well rested. My anxiety and depression are gone. I'm off depression meds. I've been hitting the gym 3x/week. Thanks to tirzepatide, I've dropped 25lbs since January 10th.
 
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