Omeprazole use alongside Triz
- Thread starter rodrom82
- Start date
CranberryRocker
Explorer
I was prescribed Omeprazole previously. Within several weeks, though, the dose I needed went down. Eventually, after a number of months, I quit it entirely. The reason someone takes it probably makes a difference. My doctor mentioned that stopping can trigger rebound acid production at first. In practice, I ended up taking it only as needed, plus Rennie chewable antacid tablets. These days it has been at least 3 months since I last used either (following a 60lb loss). Even so, when I did need them, tirz didn't make them any less effective.
RaveBaddie
Explorer
Reta is what I take, and when needed I turn to Omeprazole or Pantoprazole (these were given to me for acid reflux stemming from a gastric sleeve operation done many years earlier).
My suggestion for you would be the same: take it only if it's truly needed.
From what I've noticed, the acid reflux gets less as your system adapts to the peptide over time.
It might also ease the acid problems that come with Tirz.
Gr33dyOctopus
Explorer
They pair up quite nicely, in fact. Many folks get concerned about using specific acid-reflux medications over the long haul, but speaking from my own experience, the harm that reflux itself can inflict on your system is probably far greater than any long-term impact from omeprazole.
Week 1 of TRiz for me.
Omiprazole has been part of my routine because in the past I dealt with a lot of acid reflux problems triggered by medication that brings it on. Naturally I don't use it every day, only when I sense it coming or notice early signs of acid reflux (inflammation included).
Still, it's reassuring that I can continue taking it whenever needed.
To deal with the initial high acidity I obviously reach for magnesiumsubcarbonaat or natriumbicarbonate.
stomach pain is no joke
Memory problems are one of the effects.
So i'm running Semax cycles (300mcg, 4 weeks on/off) together with cu-gk, taken as a nasal spray.
Even so, staying off these things entirely would be preferable.
Right now i'm only 2 days into week 1, so nothing feels different so far.
Still, it's very early..
FartfulCodger
Explorer
Omeprazole did the job really well for me. Similar to what other people have reported, after a few weeks I found I could stop taking it. By then, I didn't require antacid either.
chewonmysac
Explorer
During month 2 I was on Omeprazole, yet after my system got used to eating lean, green, and protein-clean, I managed to quit it. Sort of amusing what happens when you give your body proper fuel. Gas is still something I deal with now, though it exits the opposite side. After switching to grey Tirz, I've been able to fart on command and do it loudly, but there's never any odor. Has to be some Ancient Chinese Secret formula.
turlian
Explorer
My gastroenterologist prescribed omeprazole for me, and she's aware that I've been on Semaglutide too. The sole issue she raised was whether I'd get sufficient B12.
wheymaster1
Explorer
When I began tirz a year ago, I took esomeprazole, but after 1 month I quit since I no longer needed it. My reflux disappeared. Yours will disappear too. You’ll figure out how to consume smaller portions and choose foods that are kinder to the stomach (less fats, and heavy sauces ). Even so, there’s no danger in continuing omeprazole long term.
Since acid reflux is something I deal with, omeprazole is part of my routine.
Can I keep taking it? And might it help offset some of the acid problems that come with Triz?
My meals have included salads, soups, Wey shakes, smoked fish, smoked chicken, Pearl couscous, light yogurt dressing, buratta, stragiatelly, cottage chease, 1 slice of full grain bread per day, and poke bowl with no mayo. I'm careful with seasoning, and everything is freshly prepared.
Fruits too, obviously, plus low fat greek yogurt that's high in Proteine, and granola that has no sugar and is gluten free.
I can't figure out what might be triggering the acid issues.
Can I keep taking it? And might it help offset some of the acid problems that come with Triz?
My meals have included salads, soups, Wey shakes, smoked fish, smoked chicken, Pearl couscous, light yogurt dressing, buratta, stragiatelly, cottage chease, 1 slice of full grain bread per day, and poke bowl with no mayo. I'm careful with seasoning, and everything is freshly prepared.
Fruits too, obviously, plus low fat greek yogurt that's high in Proteine, and granola that has no sugar and is gluten free.
I can't figure out what might be triggering the acid issues.
wheymaster1
Explorer
Consider reducing how much you eat at each sitting — go with smaller servings. What I found was that even though I wasn't as hungry and felt full sooner, I kept piling my plate the same way I used to back when I was overweight. That's a habit that fades over time. Using smaller dishes helps, and so on.
laansasa
Explorer
Iron gets depleted too, from what I've experienced. Don't ask me how I found that out, haha
FartfulCodger
Explorer
There do appear to be certain risks that emerge over a longer horizon. As Gemini AI puts it:
"When omeprazole is taken long-term (usually beyond 1 year), it has been tied to deficiencies in nutrients (including vitamin B12 and magnesium), a greater chance of bone fractures, and somewhat higher vulnerability to gut infections such as C. difficile. Rare kidney issues may also be connected to it."
With that said, my own experience matched yours: I reached a point where it simply wasn't necessary. I lowered my dosage until I was taking 1 pill every few days. Eventually I stopped taking it altogether, and the heartburn/reflux stayed away permanently. My guess is that this came down to shifts in what I eat--shifts I intend to keep up whether or not GLP-1 meds are part of the picture. For me, I believe eating less was the main factor that made the difference.
So far, anti-reflux medication (the chewable kind plus something for acid reflux) has only been necessary for me on 3 occasions.
At this point I'll take it one day at a time and see whether it's needed. That means improving my diet, cutting back on heavy spices, and avoiding anything with sour in it — foods and dressings alike.
Still, I appreciate all the advice and encouragement up to now.
At this point I'll take it one day at a time and see whether it's needed. That means improving my diet, cutting back on heavy spices, and avoiding anything with sour in it — foods and dressings alike.
Still, I appreciate all the advice and encouragement up to now.
Omeprazole has been part of my routine for years.
A couple of times I tried to stop, but the acid returned, so my Doc advised me to keep taking it.
Because food lingers longer in the digestive tract with GLP1s, acid reflux tends to show up as a common side effect.
Like others here, I'd say that when your diet is restricted, you have to keep an eye on all Vit/Nutrients and add supplements to match.
I wish I could quit.. But spicy food is my weakness, and Thai peppers, Serrano peppers, and Jalapenos give me low calorie plus high VitC.
A nice Salad with avocado and fresh salsa is worth trying- only good fat, low cal, and tasty.. but I need my Prilosec or I'll regret it
A couple of times I tried to stop, but the acid returned, so my Doc advised me to keep taking it.
Because food lingers longer in the digestive tract with GLP1s, acid reflux tends to show up as a common side effect.
Like others here, I'd say that when your diet is restricted, you have to keep an eye on all Vit/Nutrients and add supplements to match.
I wish I could quit.. But spicy food is my weakness, and Thai peppers, Serrano peppers, and Jalapenos give me low calorie plus high VitC.
A nice Salad with avocado and fresh salsa is worth trying- only good fat, low cal, and tasty.. but I need my Prilosec or I'll regret it
Blueeyedme
Explorer
For years I've taken 10mg each morning because of reflux that hits at night. I haven't stopped. When I'm on tirz, I barely eat anything past 3pm for the 3 days following my injection…if I do, I'll wake up during the night with reflux.
YoYoFat
Explorer
As other people have said, once I began Tirz, I no longer required omeprazole or any kind of antacid. I had been asking myself whether my HRT estrogen might be responsible.
eidos
Explorer
In my first 12 months of GLP-1 treatment on Victoza, a big bottle of Sriracha would last me about 3 months, and I added cayenne pepper since the heat wasn't strong enough. A bottle of Tabasco was gone within 14 days, so I quit using it...Skidude said:
Omeprazole has been part of my routine for years.
A couple of times I tried to stop, but the acid returned, so my Doc advised me to keep taking it.
Because food lingers longer in the digestive tract with GLP1s, acid reflux tends to show up as a common side effect.
Like others here, I'd say that when your diet is restricted, you have to keep an eye on all Vit/Nutrients and add supplements to match.
I wish I could quit.. But spicy food is my weakness, and Thai peppers, Serrano peppers, and Jalapenos give me low calorie plus high VitC.
A nice Salad with avocado and fresh salsa is worth trying- only good fat, low cal, and tasty.. but I need my Prilosec or I'll regret it
Strangely, Tirz didn't produce the same result for me.
Reflux still hits me occasionally, though it improves when I steer clear of fatty meals at night. Even before GLP-1, I'd already figured out that late-night chocolate and beer were off the table.
It varies from one individual to another and from one food to another. Work out your own triggers and which food combinations spell trouble.
Putting on weight (starting weight 138kg / 304lbs) was partly down to how I ate — I was hooked on samurai saus (that chili mayo), and I'd have it with anything. Then stress plus a bunch of other poor decisions left me with stomach inflammation, and after that I couldn't handle much spice anymore. If I do eat it, I end up waking at night with acid reflux. no bueno