My switch from tirzepatide to retatrutide: what I've noticed so far

mcpeligro

mcpeligro

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Hi,

For roughly 6 months I was on mounjaro and the results have left me really pleased. I dropped 20Kg, and out of that only 1,7 was muscle. My reason for starting wasn't just vanity (I train a lot) — it was a knee injure, and I was advised to shed some weight.

Very intense training 6 Days a week plus a heavily cut cals diet, 150g of protein, plenty of vegs, and 0 food noise ... bammm.. the perfect combo. By agust I was at 11% of body fat.The catch is that mounjaro, as many of you already know, costs a fortune, at least here in Spain, so right after coming back from holidays I began with Rt.

Now I'm in my third week, starting from 0.5 the first week (nothing ... lots of food noises that took a huge effort to control), Second week 1.0 (something started to register, less food noise, no apparent second effects), Third week 1.5 (very little food noise now but I can still eat normal), my plan its to move up to 2.5 on the 5 week adding 0.5 each week and then stay there for about 8 weeks. The scale says almost the same as when I got back from holidays but the mirror shows the difference, and I've now halved the cal deficit I was running on mounjaro.

I also began the klow for skin firmness , but I'll share results in some weeks.

Sorry about my English jejeje I gave it my best and didn't want to use ai. jejejej
 
I'd raise the dose to 2mg and keep it at that level for 3-4 weeks, or extend it if the food noise stays manageable. 2.5 would likely work too, but what's the point? Titration takes roughly a month.
 
Retatrutide needs roughly 4-5 weeks to reach full saturation in your body. So if you bump up your dose just 1 week later, there is no way to tell whether that dose has actually had time to work yet. My advice: take it slower, and hold each dose for at least 3-4 weeks before going higher.
 
I don't get it. If tirzepatide was working so well, what's the reason for moving to retatrutide? You had to have access to tirzepatide, given that you turned to the grey market for retatrutide, right?
 
Trying out a new option never happens quickly.

Still, @gusterbuster raised the same point I'm wondering about — given how well tirz worked for you, what's the reason for not sticking with it?

My approach has always been: ''If it's not broken, why fix it?''
 
gusterbuster said:

I don't get it. If tirzepatide was working so well, what's the reason for moving to retatrutide? You had to have access to tirzepatide, given that you turned to the grey market for retatrutide, right?
Click to expand...
I'm wrestling with the same decision. Should I begin with Tirzepatide and observe its effects, or should I go straight to Retatrutide? I realize Retatrutide has impressive advantages, but I'm leaning toward using Tirzepatide first and keeping Retatrutide in reserve for later. Yet those Retatrutide benefits are tempting, and that's exactly why I haven't placed my initial order yet. I suppose I'm caught in a loop of overthinking... at least it buys me extra time to research.
 
About 3 or 4 months back, I went through the same transition you're just beginning. At this point reta seems to be at full effect for me, and every so often I'll reintroduce a bit of Tirz since I believe it eases joint inflammation. If I were to switch to reta from Tirz all over again, my starting dose would have been 2mg instead of the .5 then 1mg steps I took over several weeks. On the scale, I gave up a couple months of forward movement. The primary reason I wanted reta was the liver visceral fat reduction seen in trials. In hindsight, staying on Tirz right up until it stopped delivering results would have been the better call. For the time being I'm largely satisfied with reta and have noticed body recomp, though I can't say whether that's reta's doing or simply my body reacting to the overall weight loss. One more thing: Tirz was a big help against food noise, whereas reta... not really. With reta you still want to eat, but you're able to eat far less. That's how it's gone for me, and everyone responds differently. Wishing you the best.
 
oldjarhead said:

About 3 or 4 months back, I went through the same transition you're just beginning. At this point reta seems to be at full effect for me, and every so often I'll reintroduce a bit of Tirz since I believe it eases joint inflammation. If I were to switch to reta from Tirz all over again, my starting dose would have been 2mg instead of the .5 then 1mg steps I took over several weeks. On the scale, I gave up a couple months of forward movement. The primary reason I wanted reta was the liver visceral fat reduction seen in trials. In hindsight, staying on Tirz right up until it stopped delivering results would have been the better call. For the time being I'm largely satisfied with reta and have noticed body recomp, though I can't say whether that's reta's doing or simply my body reacting to the overall weight loss. One more thing: Tirz was a big help against food noise, whereas reta... not really. With reta you still want to eat, but you're able to eat far less. That's how it's gone for me, and everyone responds differently. Wishing you the best.
Click to expand...

That's precisely what I did — I introduced reta at 2mg, because I'd been on Tirz for quite a while and it wasn't delivering the results I was after, plus I had no interest in pushing up to a really high dose. My starting point with reta was 2mg, and it complements Tirz beautifully.
 
RandomCrew said:

gusterbuster said:

I don't get it. If tirzepatide was working so well, what's the reason for moving to retatrutide? You had to have access to tirzepatide, given that you turned to the grey market for retatrutide, right?
Click to expand...
I'm wrestling with the same decision. Should I begin with Tirzepatide and observe its effects, or should I go straight to Retatrutide? I realize Retatrutide has impressive advantages, but I'm leaning toward using Tirzepatide first and keeping Retatrutide in reserve for later. Yet those Retatrutide benefits are tempting, and that's exactly why I haven't placed my initial order yet. I suppose I'm caught in a loop of overthinking... at least it buys me extra time to research.
Click to expand...
The choice is yours to make. Reta is the latest craze and pulls in clicks, which is why you see content about it everywhere.

I'll just point out that a pattern seems to be emerging where people on Reta move over to Tirz for maintenance. I'm in that group myself. I'm not sold on the idea that a higher resting heart rate and lower heart rate variability are beneficial over the long haul.
 
jejeje alright, I wasn't planning to... but... Time for the cringe-worthy tale:

mounjaro was working fine for me, except for one thing: the cost... So I headed to this forum plus a few other places and began reading up on rt and other peps, and I told myself fine, I'll grab some from the grey market, what's the worst that could happen?? . So after chatting with plenty of professional scammers over ws, I found one that ships to madrid with a pay on delivery setup, ideal!! right? so I placed an order for tr since I didn't want to switch, even after reading a ton about rt (more fat, could eat more, glucagon activation, etc...) , and the following week I also ordered rt from a recommended grey marketer. 2 weeks later the pay on deliver tr arrived, and I had run out of mounjaro, and I was heading off on holiday... so I mixed it up and gave it a try.... first with a some units and the next day with the 5mg dose I was getting on mounjaro... nothing happens.. like inyecting water... next week the same. And then the reta showed up right when I got back from holidays... so I had no chance... jejejej..

Now this week I got and order with a friend (with lots of expertise in this things) and I got rt,tr,klow, so now i'm staing with reta for 8 weeks and then check the results
 
gusterbuster said:

RandomCrew said:

gusterbuster said:

I don't get it. If tirzepatide was working so well, what's the reason for moving to retatrutide? You had to have access to tirzepatide, given that you turned to the grey market for retatrutide, right?
Click to expand...
I'm wrestling with the same decision. Should I begin with Tirzepatide and observe its effects, or should I go straight to Retatrutide? I realize Retatrutide has impressive advantages, but I'm leaning toward using Tirzepatide first and keeping Retatrutide in reserve for later. Yet those Retatrutide benefits are tempting, and that's exactly why I haven't placed my initial order yet. I suppose I'm caught in a loop of overthinking... at least it buys me extra time to research.
Click to expand...
The choice is yours to make. Reta is the latest craze and pulls in clicks, which is why you see content about it everywhere.

I'll just point out that a pattern seems to be emerging where people on Reta move over to Tirz for maintenance. I'm in that group myself. I'm not sold on the idea that a higher resting heart rate and lower heart rate variability are beneficial over the long haul.
Click to expand...
I find this interesting, since one protocol I'm considering involves running Reta for 24-30 weeks to reach GW 1, then moving over to Tirz — that way I'd get the advantages of both, with Tirz handling maintenance.
 
A small update:

The number on the scale finally dipped a bit today. This whole week at 1.5 has gone about as well as I could ask. Hard training is no problem, the food noise is gone (well, some is still there, but I can manage it), and the best part is that the diet keeps moving forward because I actually have room to eat. On trz I never felt hungry and had to push myself to eat; on rt this week there's no noise, yet I can still get through what the diet calls for, which is exactly what I need to hit my protein target.

On the downside, sleep has become genuinely difficult, even though my heart rate is unchanged from when I wasn't on rt (I track it with whoop)... I can't pin that on rt though, since work has been crazy these weeks... so it's hard to say.

As for the klow, I can't notice any difference at this point...
 
RandomCrew said:

gusterbuster said:

RandomCrew said:

gusterbuster said:

I don't get it. If tirzepatide was working so well, what's the reason for moving to retatrutide? You had to have access to tirzepatide, given that you turned to the grey market for retatrutide, right?
Click to expand...
I'm wrestling with the same decision. Should I begin with Tirzepatide and observe its effects, or should I go straight to Retatrutide? I realize Retatrutide has impressive advantages, but I'm leaning toward using Tirzepatide first and keeping Retatrutide in reserve for later. Yet those Retatrutide benefits are tempting, and that's exactly why I haven't placed my initial order yet. I suppose I'm caught in a loop of overthinking... at least it buys me extra time to research.
Click to expand...
The choice is yours to make. Reta is the latest craze and pulls in clicks, which is why you see content about it everywhere.

I'll just point out that a pattern seems to be emerging where people on Reta move over to Tirz for maintenance. I'm in that group myself. I'm not sold on the idea that a higher resting heart rate and lower heart rate variability are beneficial over the long haul.
Click to expand...
I find this interesting, since one protocol I'm considering involves running Reta for 24-30 weeks to reach GW 1, then moving over to Tirz — that way I'd get the advantages of both, with Tirz handling maintenance.
Click to expand...

If you ask me, the smart play when changing compounds isn't a sudden swap — it's a gradual handover. Picture finishing 24-30 weeks sitting at 8-10mg of reta. From there, I'd add a split dose of 2.5mg tirz, taken 3-4 days after the reta shot, while trimming the reta by 2-4mg. Then, 2-4 weeks down the line, I'd raise tirz to whatever I figure a maintenance dose should be, and shave another 2-4mg off the reta. Yeah, I know — that's just how I'd do it. GL
 
mcpeligro said:

A small update:

The number on the scale finally dipped a bit today. This whole week at 1.5 has gone about as well as I could ask. Hard training is no problem, the food noise is gone (well, some is still there, but I can manage it), and the best part is that the diet keeps moving forward because I actually have room to eat. On trz I never felt hungry and had to push myself to eat; on rt this week there's no noise, yet I can still get through what the diet calls for, which is exactly what I need to hit my protein target.

On the downside, sleep has become genuinely difficult, even though my heart rate is unchanged from when I wasn't on rt (I track it with whoop)... I can't pin that on rt though, since work has been crazy these weeks... so it's hard to say.

As for the klow, I can't notice any difference at this point...
Click to expand...
For roughly 2 months, my sleep was a mess. I was getting maybe 4.5 to 5 hours each night, and the amount crept up gradually as time went on. What made the sleep issue rough was that once I woke up, I was completely alert and there was no way I could fall back asleep. These days sleep has improved a lot, though it is still not as much as it used to be....I manage about 6 to nearly 7 hours, and I still wake up with my eyes wide open.
 
Flash-BCR said:

RandomCrew said:

gusterbuster said:

RandomCrew said:

gusterbuster said:

I don't get it. If tirzepatide was working so well, what's the reason for moving to retatrutide? You had to have access to tirzepatide, given that you turned to the grey market for retatrutide, right?
Click to expand...
I'm wrestling with the same decision. Should I begin with Tirzepatide and observe its effects, or should I go straight to Retatrutide? I realize Retatrutide has impressive advantages, but I'm leaning toward using Tirzepatide first and keeping Retatrutide in reserve for later. Yet those Retatrutide benefits are tempting, and that's exactly why I haven't placed my initial order yet. I suppose I'm caught in a loop of overthinking... at least it buys me extra time to research.
Click to expand...
The choice is yours to make. Reta is the latest craze and pulls in clicks, which is why you see content about it everywhere.

I'll just point out that a pattern seems to be emerging where people on Reta move over to Tirz for maintenance. I'm in that group myself. I'm not sold on the idea that a higher resting heart rate and lower heart rate variability are beneficial over the long haul.
Click to expand...
I find this interesting, since one protocol I'm considering involves running Reta for 24-30 weeks to reach GW 1, then moving over to Tirz — that way I'd get the advantages of both, with Tirz handling maintenance.
Click to expand...

If you ask me, the smart play when changing compounds isn't a sudden swap — it's a gradual handover. Picture finishing 24-30 weeks sitting at 8-10mg of reta. From there, I'd add a split dose of 2.5mg tirz, taken 3-4 days after the reta shot, while trimming the reta by 2-4mg. Then, 2-4 weeks down the line, I'd raise tirz to whatever I figure a maintenance dose should be, and shave another 2-4mg off the reta. Yeah, I know — that's just how I'd do it. GL
Click to expand...
Thanks for that. Still, my plan is to begin with Reta and then switch over to Tirz when it comes time for maintenance, so I'll just have to wait and find out.
 
update:

At 2.5 of reta, the results are amazing. Compared with tr, the scale moves more slowly, but muscle and lean mass are getting better, so if I only drop 0.2 kg while adding 0.3 of muscle, that is great news, and the mirror shows it!!!

Klow is working too, and my hair feels a bit thicker!!!...
 
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