MOTS-c Shows Anti-Tumor Properties

[diplomat]

Exogenous MOTS-c can inhibit OC cell growth in vitro and in vivo. Mechanistically, MOTS-c exerted anti-cancer effects by attenuating USP7-mediated deubiquitination of LARS1 and promoting LARS1 degradation. Our study revealed for the first time that MOTS-c serves as an antitumor peptide to inhibit OC progression, and thus could be a potential target for future OC diagnosis and treatment.

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It looks like a promising anti-cancer agent, (in the paper, 'OC' stands for Ovarian Cancer) although so far it has only been tested in mice and petri dishes.

I won't claim to understand even 10% of it, but here are the details -

Chinese research paper.

 

[Clavicular's Hammer]

Nice, from the look of it, direct translation to people would mean months of running — but that's not the way science operates

Fingers crossed we get human trials down the line

Given the mechanism they suggest, if it pans out as theorized, the same approach might apply to lung, colon, breast and liver cancers. It might also prove useful against prostate, melanoma, gliobastoma, pancreatic and gastric cancers too.