dogmom
New member
They have been out of stock for a while now. I don't know if they are ever going to restock unfortunately. That is where I got from a year or so ago.
Looking at tesofinsine
- Thread starter Airborne Daddy
- Start date
Torque
New member
EZ went out of stock recently as well. I feel like most places have the capsules. If I ever tried it I would want the tablets so I could attempt to split them into very small doses.
Jack brown
New member
What do you think of pairing it with propanalol or similar?
lessthanhalf
New member
As far as I remember there was actually a clinical trial combining it with a beta blocker to reduce side effects, cannot remember the name but should be findable on google scholar. In theory beta blockers can increase weight a tiny bit, maybe a percent or 2, nebivolol or carvedilol are the beta blockers least likely to cause weight gain or increase blood sugar. In Aus these may be less available on standard prescriptions though, whereas propanalol is readily available and not restricted.
It looked like they were slowly developing tesofensine with the aim of actually getting it approved, but it seems to be in limbo now ,( like 90 % of drugs that never quite make it ) presumably after ozempic came out it was thought it could not compete.
But using tesofensine with a beta blocker is reasonable. Ideally this should be discussed with a doctor first, and you would need to have a good understanding of the possible side effects and contraindications if going it alone, and get blood pressure and electrolytes checked before and after starting it.
Looking at the pills seen above , they look big enough that crushing or cutting in half to get partial doses would not be an issue. You can buy tesofensine in multigram quantities on ebay, but because the dose is so low, under 0.5mg, you would need very accurate scales, the standard cheap ones on Amazon are not good enough, I tried using my scales to measure 5 and 10mg doses the other day and they were not good enough, but were ok for 25mg doses, thankfully the little tiny 5 and 10mg spoons on amazon were accurate enough to measure out those doses so long they do not need to be accurate ( plus or minus 50% was good enough ) , but I would guess scales accurate in mcg would be expensive. They would need to be at least 50-100x more accurate than the 20 or 30 dollar ones I got or plus or minus 25-50 mcg to get even somewhat accurate doses.
It looked like they were slowly developing tesofensine with the aim of actually getting it approved, but it seems to be in limbo now ,( like 90 % of drugs that never quite make it ) presumably after ozempic came out it was thought it could not compete.
But using tesofensine with a beta blocker is reasonable. Ideally this should be discussed with a doctor first, and you would need to have a good understanding of the possible side effects and contraindications if going it alone, and get blood pressure and electrolytes checked before and after starting it.
Looking at the pills seen above , they look big enough that crushing or cutting in half to get partial doses would not be an issue. You can buy tesofensine in multigram quantities on ebay, but because the dose is so low, under 0.5mg, you would need very accurate scales, the standard cheap ones on Amazon are not good enough, I tried using my scales to measure 5 and 10mg doses the other day and they were not good enough, but were ok for 25mg doses, thankfully the little tiny 5 and 10mg spoons on amazon were accurate enough to measure out those doses so long they do not need to be accurate ( plus or minus 50% was good enough ) , but I would guess scales accurate in mcg would be expensive. They would need to be at least 50-100x more accurate than the 20 or 30 dollar ones I got or plus or minus 25-50 mcg to get even somewhat accurate doses.
RadicalCrimson
New member
It was metoprolol, the studies showed that combining both negated the impact on heart rate.
There is a trustworthy vendor online that offers both in liquid form.
rch02474
New member
Did you ever research this further? Became interested after hearing about the focus and metabolic benefits. Now I'm thinking I should proceed VERY cautiously given all the reports of side effects.
Calm Logic
New member
There are places that sell an oral liquid form. But as a reta fanboi, not interested in teso.