monel12345
Explorer
3 weeks into Reta and it’s definitely hitting me. Still, visceral fat is my main target, so I’m considering adding Tesa to the mix. What’s everyone else running?
INTRO Who’s stacking Reta & tesa
- Thread starter monel12345
- Start date
lluna45469
Explorer
My dear, take your time—don't rush. I know you will surely become even more wonderful.
I can’t tell you what’s smart here or hand out advice about something that sits in the grey zone—so do whatever you want to do. That said, my view is that you ought to hold off on combining peptides until you’ve been stuck at a major plateau and/or haven’t seen progress for a stretch. Fat loss can’t constantly be quick, and it can’t be spot-specific (unfortunately). I realize this isn’t what you were hoping to hear, but I hope you get what I’m saying!
Goodluck on you weightloss journey!
Goodluck on you weightloss journey!
Galapagosfit
Explorer
when you're at the point of maintaining your goal weight and tapering off Reta, do you figure Tesa might be useful then?
monel12345
Explorer
Got respect for that, man. So keeping the Reta cycle solo would be the smarter call.
tesamorelin is a peptide/medicine intended for patients who store fat abnormally in the abdomen. in 9 out of 10 cases it is administered in a professional setting, to patients who have HIV and use specific medications that bring this on. research indicates that once tesamorelin is stopped, the outcomes achieved will revert to how they were before, and this applies equally to healthy individuals who are not on HIV medication. the reason is that abdominal fat reacts very strongly to hormonal shifts. unfortunately, lifestyle changes alone cannot correct this or hold onto the result.
now, regarding your question, plus a little extra on retatutride and the rebound effect.
the primary explanation studies show weight coming back is that those individuals lacked proper coaching and/or did not make the lifestyle changes/adaptations required to preserve the results, or to keep weight gain as small as possible, when stopping the drug.
GLP-1 medication (such as retatutride) does not act directly on your body’s hormonal balance, it imitates it. so when you stop the drug or (strongly advised) taper it down:
hormonal balance largely remains unchanged
does not act directly on fat storage
the mimicked hunger/fullness effect will gradually fade back.
this means there is a very large and/or strong possibility the weight can simply remain at the desired body weight, but only alongside the right lifestyle changes and dietary adaptations. the reason is that after quitting retatutride your baseline energy expenditure (the energy burned at complete rest) will drop. that requires adjustment to stay at the weight you want.
and this is all just personal advice, not medical advice! also, once more, and i truly want to stress this: you have to make your own decision about what to do, taking tesa and/or reta is your own choice. i am only sharing info based on my experience and the deep search into what each peptide does and the risks attached.
so if you want to quit retatutride, taper down slowly, for example:
8 mg a week=
6,5/7 mg week taper for 4 weeks
5,5 mg for also 4 or if the hunger is really bad even 6 weeks.
why taper so slowly? because the body has to readjust to the lower level of medicine. this makes a big difference in rebound effect.
get to your lowest dose that you can handle and maybe even stay there for 8/10 weeks, this is again just adjustment. if things really get difficult because you feel this intense urge of eating, then there are in my opinion or what i would/gonna do is.
1.stay on that difficult dose a bit longer (body really just needs to adjust and get out of this emergency mode of ‘we don’t have enough food!!’.) and that takes time.
2. (big maybe) invest in some cagrilintide. that peptide is also in big research and i acts in a different way than glp-1. it makes youre more full when you eat and could also effect the hunger and binge eating.
if you would take the second option make sure, take the lowest dose maybe even micro dose. its to help you maintaining and getting of the reta.
this is how i would do it. no bullshit info and just straight up info about the peptides and effects of them.
(no medical advice again and everything is a risk you are willing to take. i am just providing info and what you do with it is you're choice!)
hope this helps guys!! i wanted to answer with some accurate info i could find on studies and people their experience. that is why my answer took a bit longer!
indeed! and take a look at my separate response covering the typical effects of these peptides!
once more, it’s great that you’ve joined this platform, and i want you to make carefully thought-out choices regarding these peptides.
i hope your time here—and your journey—turns out really well. don’t hesitate to ask anything. i hope i’ll spot your questions fast and get back to you!
wishing you a fantastic day!!
Galapagosfit
Explorer
Appreciate it — great response, plenty of useful info there.No name said:
tesamorelin is a peptide/medicine intended for patients who store fat abnormally in the abdomen. in 9 out of 10 cases it is administered in a professional setting, to patients who have HIV and use specific medications that bring this on. research indicates that once tesamorelin is stopped, the outcomes achieved will revert to how they were before, and this applies equally to healthy individuals who are not on HIV medication. the reason is that abdominal fat reacts very strongly to hormonal shifts. unfortunately, lifestyle changes alone cannot correct this or hold onto the result.
now, regarding your question, plus a little extra on retatutride and the rebound effect.
the primary explanation studies show weight coming back is that those individuals lacked proper coaching and/or did not make the lifestyle changes/adaptations required to preserve the results, or to keep weight gain as small as possible, when stopping the drug.
GLP-1 medication (such as retatutride) does not act directly on your body’s hormonal balance, it imitates it. so when you stop the drug or (strongly advised) taper it down:
hormonal balance largely remains unchanged
does not act directly on fat storage
the mimicked hunger/fullness effect will gradually fade back.
this means there is a very large and/or strong possibility the weight can simply remain at the desired body weight, but only alongside the right lifestyle changes and dietary adaptations. the reason is that after quitting retatutride your baseline energy expenditure (the energy burned at complete rest) will drop. that requires adjustment to stay at the weight you want.
and this is all just personal advice, not medical advice! also, once more, and i truly want to stress this: you have to make your own decision about what to do, taking tesa and/or reta is your own choice. i am only sharing info based on my experience and the deep search into what each peptide does and the risks attached.
so if you want to quit retatutride, taper down slowly, for example:
8 mg a week=
6,5/7 mg week taper for 4 weeks
5,5 mg for also 4 or if the hunger is really bad even 6 weeks.
why taper so slowly? because the body has to readjust to the lower level of medicine. this makes a big difference in rebound effect.
get to your lowest dose that you can handle and maybe even stay there for 8/10 weeks, this is again just adjustment. if things really get difficult because you feel this intense urge of eating, then there are in my opinion or what i would/gonna do is.
1.stay on that difficult dose a bit longer (body really just needs to adjust and get out of this emergency mode of ‘we don’t have enough food!!’.) and that takes time.
2. (big maybe) invest in some cagrilintide. that peptide is also in big research and i acts in a different way than glp-1. it makes youre more full when you eat and could also effect the hunger and binge eating.
if you would take the second option make sure, take the lowest dose maybe even micro dose. its to help you maintaining and getting of the reta.
this is how i would do it. no bullshit info and just straight up info about the peptides and effects of them.
(no medical advice again and everything is a risk you are willing to take. i am just providing info and what you do with it is you're choice!)
hope this helps guys!! i wanted to answer with some accurate info i could find on studies and people their experience. that is why my answer took a bit longer!
All I can share comes from what I’ve tried personally with my RS. Right when I began researching peptides, I gave Reta, Tesa/IPA, and MOTS-C, each at the suggested starting dose. My RS dropped roughly 10lbs over the course of 6 weeks. Just remember that on their own, these peptides aren’t miracle weight-loss fixes. Sure, over time they might assist with dropping weight. Still, managing what you eat and adding some form of exercise will make a huge difference in getting where you want to be.
Tempting as it is to throw everything in from day 1, my take is that you should first settle on Reta, dialing it up until you hit the dose that works best for you, and only after that introduce Tesamorelin — that way you can actually tell what each one is doing at a given dose.
Pumpmeboy1974
Explorer
That's a smart approach...I'm leaning toward following it. Right now I'm moving off Sem/Tirz onto Ret ... once I see the results from that, I'll layer in the visceral fat reduction peps afterward, so I can tell which one is doing the work.
Florus2026
Explorer
Down the line I’m planning to do the same thing. My goal isn’t really dropping pounds—it’s targeting visceral fat. I even went as far as attempting to obtain it for my dad through his physician in a "legal" manner, only to discover that the official medication isn’t approved in Austria, so that route is closed.
When it comes to peptides in general, I find the material from Swolverine useful—I’m not certain whether external links are allowed here, but a Google search for that plus Tesa turns up their guidance and so on. One of their suggestions is using it to "tighten up" after you’ve reached or are near your goal weight. Since Reta and Tesa work through different pathways, I can’t see any reason not to combine them. Right now I’m on a low dose of Reta and have introduced Ipa/CJC alongside it during training to hold onto muscle. I still need to place an order for Tesa, but after it arrives I’ll rotate it in and give it a try.
Right now I’m on Reta, and my supply of the pricey Tesa has arrived—likely lasting 2months. My plan is to start it once I’m done with the CJC+Ipa vial I’m currently using, since both are GH secretagogues and running them together would be redundant. I’ll return to this thread once it’s underway.
Cynthianoob
Explorer
I'm considering a comparable approach, though I plan to hold off a few weeks prior to adding anything else.. I'm still acclimating to the single reta first
RicFlair
Explorer
I'm jumping in on this thread since I've been running reta for roughly 1.5 weeks and have a tesa kit on the way, expected to land either this week or the next. Reta agreed with me pretty much right away, so after researching tesa for a while I pulled the trigger on a kit and plan to stack it alongside reta, mainly because visceral fat and a belly are issues for me. My advice would also be to hold off until you've adapted to the reta if that hasn't happened yet, then reassess whether bumping the dose or bringing in a second compound makes sense
ThunderBird
Explorer
When you recon Tesa, stay cautious — it’s certainly among the more unpredictable compounds.
gimmeshelter
Explorer
My take is this: start with reta on its own. That way you'll have a clear picture of how it feels and what it's actually doing for u. After you've adjusted to that, or once progress stalls, that might be the point to bring in Tesa ( I want to do the same) . Adding it later means u can better tell what Tesa is contributing beyond reta.
It's tempting to stack right away, but doing that can leave u unsure about what's really happening, and placebo effect can trip u up. Ohhh , and hello from eastern nc as well. Gville area.
soesfairview
Explorer
I've only just begun Tessa alongside Reta, so it's far too early for me to report anything. With any luck, another month or so will bring some visible results.
BoxerLover
Explorer
What is it that causes the volatility?