INTRO Started with Ozempic in 2019 now on Reta

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Clarkyboy

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Hello everyone!

My journey with GLP-1 medications started back when Ozempic was prescribed to me for weight loss, well before GLP-1s became a huge trend. I stayed on it for several months, following my doctor's instruction to use and remain at 1mg. Somewhere around month 3 or month 4, a serious adverse effect appeared: stomach paralysis, which left food sitting and decaying in my stomach. I stopped GLP-1s entirely until last week, when I administered my very first Retatrutide dose.

Given how badly things went before, I chose to begin at a low dose and increase slowly. As of today, I have taken my 2nd dose of 0.5 mg of Reta. Things have gone well so far, with no signs of gut paralysis. In fact, I suspect I may be a hyper responder, since even a mere 0.5mg hits me strongly. My appetite is suppressed, and food noise has vanished completely. The initial 2 days were quite rough, and I felt like I could not eat at all.

I stand 5'9 and weigh 116kg, hoping to eventually reach the 75-80kg range
 
Welcome. Reta also appeared to work more effectively in my case. My starting point was zepbound, which appeared to cause me some stomach problems. After that, I've incorporated several other peptides into my routine and seem to feel much better overall. I was even able to discontinue my antidepressants that I'd been taking for roughly 13 years!
 
I’d really like to hear how others have handled the switch from Tirz to Reta. What I keep seeing on Reddit is a pretty consistent pattern…hunger isn’t suppressed as strongly, resting heart rate goes up, and there are plenty of shredded younger folks.
 
NoDoz36 said:

I’d really like to hear how others have handled the switch from Tirz to Reta. What I keep seeing on Reddit is a pretty consistent pattern…hunger isn’t suppressed as strongly, resting heart rate goes up, and there are plenty of shredded younger folks.
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The reason I haven't introduced Reta alongside my Triz is exactly this. I deal with Hypertension, and a higher resting heart rate isn't something I'd want, though I'm continuing to look into it.
 
Good to know it's been smooth for you up to this point, particularly given what you went through before with Ozempic! Beginning at a low dose and ramping up gradually seems like a wise move.

Do you intend to remain at 0.5 mg for some time?
 
nycparamedic said:

NoDoz36 said:

I’d really like to hear how others have handled the switch from Tirz to Reta. What I keep seeing on Reddit is a pretty consistent pattern…hunger isn’t suppressed as strongly, resting heart rate goes up, and there are plenty of shredded younger folks.
Click to expand...
The reason I haven't introduced Reta alongside my Triz is exactly this. I deal with Hypertension, and a higher resting heart rate isn't something I'd want, though I'm continuing to look into it.
Click to expand...
Same here when it comes to doing research. At the moment, compounded Tirz is doing the job and fits my budget, so I don’t have to deal with the extra worries that come with doing grey safely. Still, the idea of keeping a large stash in the freezer appeals to me in case the rules around this change.
 
Hello! I began at a low dose too. I started at .33mg since I was pinning and praying lol. 5 weeks later, I'm now taking 1.333mg every 6 days. It's been great so far. A bit lethargic, but I've been taking some modafinil to counter the tiredness and boost energy.

I do nightshifts, so I've had a prescription for years, and reta in particular tends to drain energy on days when I get little sleep
 
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