husrim
New member
It was actually my wife's own interest that got me started. "Get me o*mpic!" she insisted about a year ago. She wanted to drop a few pounds and has struggled with the other methods. At the time I was against it, influenced by, well, influencers, talking about nausea, slowed gastric emptying, and the low compliance rate towards the end of the first year. She's perfect as she is already -- doesn't need to change anything -- and for that reason we assumed that no doctor would prescribe it, insurance wouldn't cover it, and therefore we wouldn't be able to afford it anyway.
Fast forward a year, and now some of those same influencers have discovered that GLP-1 agonists do a lot more than suppress appetite. My own assessment has changed. Now I believe that the metabolic improvements sit front-center stage, and the weight loss is just a consequence of getting healthier. And appetite is, as it always has been, just a sincere expression of energy needs at the cellular level.
My own method of weight control has been low-carb eating. It works when it works. When I'm adherent, I don't get hungry, and I become lean and remain lean. I don't exactly have food noise, but I do have carb noise. It's a constant low-level effort to avoid those carbs, even when I'm at my peak of fat adaptation. It's especially difficult because I live in a house where the walls are virtually held up by boxes and cartons of processed carbs. (Caution: teenagers present.)
Now I'm cruising on 2 mg of reta, dosed once weekly. I've lost a few pounds since starting, but that's just been a linear extension of the weight-loss trajectory of the keto diet I reinstated a few months before I added reta. Since adding reta, the shallow decline in BF% is happening without carb noise. The biggest challenge for me is meeting my daily protein goal. I use that goal to gate-keep any temptation to increase the reta dose. Current rule for myself: I have to meet the protein goal without struggle before I'm allowed to consider bumping up the reta dose. I also do resistance training in my garage 5 days/wk, and walk 5 miles a few times per week.
As for my wife, she's having a slower on-ramp to reta due to nausea. Currently hanging on at 0.4 mg dosed 2-3 times per week. She had a few days of nausea due to overeager escalation, but we've since gotten that under control and are proceeding more cautiously, with help of an app to show estimated accumulated level. It's hard to tell if she's getting the results she came here for just yet, but my viewpoint is that the current goal is just building tolerance up to the point where she can stomach a therapeutic dose.
I am the pen mechanic in the family. We share a kit, but always have our own pens, and of course, our own needles.
Fast forward a year, and now some of those same influencers have discovered that GLP-1 agonists do a lot more than suppress appetite. My own assessment has changed. Now I believe that the metabolic improvements sit front-center stage, and the weight loss is just a consequence of getting healthier. And appetite is, as it always has been, just a sincere expression of energy needs at the cellular level.
My own method of weight control has been low-carb eating. It works when it works. When I'm adherent, I don't get hungry, and I become lean and remain lean. I don't exactly have food noise, but I do have carb noise. It's a constant low-level effort to avoid those carbs, even when I'm at my peak of fat adaptation. It's especially difficult because I live in a house where the walls are virtually held up by boxes and cartons of processed carbs. (Caution: teenagers present.)
Now I'm cruising on 2 mg of reta, dosed once weekly. I've lost a few pounds since starting, but that's just been a linear extension of the weight-loss trajectory of the keto diet I reinstated a few months before I added reta. Since adding reta, the shallow decline in BF% is happening without carb noise. The biggest challenge for me is meeting my daily protein goal. I use that goal to gate-keep any temptation to increase the reta dose. Current rule for myself: I have to meet the protein goal without struggle before I'm allowed to consider bumping up the reta dose. I also do resistance training in my garage 5 days/wk, and walk 5 miles a few times per week.
As for my wife, she's having a slower on-ramp to reta due to nausea. Currently hanging on at 0.4 mg dosed 2-3 times per week. She had a few days of nausea due to overeager escalation, but we've since gotten that under control and are proceeding more cautiously, with help of an app to show estimated accumulated level. It's hard to tell if she's getting the results she came here for just yet, but my viewpoint is that the current goal is just building tolerance up to the point where she can stomach a therapeutic dose.
I am the pen mechanic in the family. We share a kit, but always have our own pens, and of course, our own needles.