INTRO Into Year 3 GLP -

zbound&down

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Hello!

Reddit is how I ended up in this space, and I'm now entering my 3rd year on Zep. When Wegovy first hit the market, my endocrinologist brought it up as an option. Insurance turned me down — no diabetes diagnosis. Ozempic met the same fate for the same reason. On top of that, I wasn't exactly eager to start a GLP1, since my understanding was that these drugs mainly curb appetite, and overeating was never my problem. My problem was the opposite: getting enough calories in each day was a struggle. That's been true my whole adult life, starting in college, when money was too tight for food and I subsisted on rice plus a gallon of water/day. Between a very active lifestyle and a LOT of effort at the gym and outside it — daily workouts (60min. Cardio, or running, walking 1 hr.+, weight training), plus a strict, whole foods, organic, diet — sustained for 20+ years, I kept a healthy weight (fluctuating between 120-130lbs, 5’6.5 F) from my late teens all the way into my mid-40’s. Then my metabolism finally crumbled. Decades of low-caloric consumption, high-energy output, hormone change, genetics, PCOS, and surely other factors I'm not even fully aware of all combined. In one year I gained 60 lbs., and at my highest I reached 235 lbs., with no change in Calories in/out.

During my first year and a half on Zepbound, 75 lbs. came off, and for over a year now not a single pound more has budged. 30 more to go. My titration was very fast, and 15 mg. has been my dose for over a year. My endocrinologist is excited for me to try Retatrutide when it comes on market, but I want to try it sooner. I'm here to learn about peptides and everything related, as I was blown away by how much of an impact Zepbound had on my broken metabolism.

More to say, much to learn, happy to be here!!!
 
Hi! From what you've said, it seems like there's plenty we share, so I'm looking forward to keeping up with how things go for you. I've been on tirz for just about 8 months, and I haven't reached the top dose yet, so in that way I'm a bit further back. Still, if switching ends up being something I face down the road, I'd really like to hear your take on how it goes.
 
Hahaha, thank you! The Danny McBride TV series “Eastbound and Down” was a favorite of mine. There’s a ton I need to learn, and right now I’m just trying to work out the best place to begin. Any roadmaps would be appreciated!
 
zbound&down said:

Hello!

Reddit is how I ended up in this space, and I'm now entering my 3rd year on Zep. When Wegovy first hit the market, my endocrinologist brought it up as an option. Insurance turned me down — no diabetes diagnosis. Ozempic met the same fate for the same reason. On top of that, I wasn't exactly eager to start a GLP1, since my understanding was that these drugs mainly curb appetite, and overeating was never my problem. My problem was the opposite: getting enough calories in each day was a struggle. That's been true my whole adult life, starting in college, when money was too tight for food and I subsisted on rice plus a gallon of water/day. Between a very active lifestyle and a LOT of effort at the gym and outside it — daily workouts (60min. Cardio, or running, walking 1 hr.+, weight training), plus a strict, whole foods, organic, diet — sustained for 20+ years, I kept a healthy weight (fluctuating between 120-130lbs, 5’6.5 F) from my late teens all the way into my mid-40’s. Then my metabolism finally crumbled. Decades of low-caloric consumption, high-energy output, hormone change, genetics, PCOS, and surely other factors I'm not even fully aware of all combined. In one year I gained 60 lbs., and at my highest I reached 235 lbs., with no change in Calories in/out.

During my first year and a half on Zepbound, 75 lbs. came off, and for over a year now not a single pound more has budged. 30 more to go. My titration was very fast, and 15 mg. has been my dose for over a year. My endocrinologist is excited for me to try Retatrutide when it comes on market, but I want to try it sooner. I'm here to learn about peptides and everything related, as I was blown away by how much of an impact Zepbound had on my broken metabolism.

More to say, much to learn, happy to be here!!!
Glad you're here! I'm only beginning to dig into all of this. Seems like a solid community that can lend a hand to us
 
Absolutely, I feel the same way! I'm doing my best to fit my research into a packed timeline, and I'm glad this community came into my life!
 
Welcome! There's tons of useful stuff to learn around here. I've been digging into Reta quite a bit, but since Tirz has worked so well for me at low doses, I decided switching isn't worth it right now.

After such a long stretch on a GLP1, have you picked up on anything? I'm always wondering, since I've only used them for a bit more than a year and never went past 2.5 mg. Are you taking your 15mg each week?
 
exxige said:

Welcome! There's tons of useful stuff to learn around here. I've been digging into Reta quite a bit, but since Tirz has worked so well for me at low doses, I decided switching isn't worth it right now.

After such a long stretch on a GLP1, have you picked up on anything? I'm always wondering, since I've only used them for a bit more than a year and never went past 2.5 mg. Are you taking your 15mg each week?
Hey! Thanks so much for the warm welcome! I take a 15 mg. vial each week. After this much time on Zep, my strong suggestion is to remain on the smallest dose you can for as long as it keeps working, and only move up once it stops doing the job — which sounds exactly like your approach! Beyond that, the additional benefits I've noticed — mental clarity, reduced inflammation, and less joint pain — have made such a difference in my life that I can't picture returning to a life without this, or some other GLP. That's the reason I'm here… It's also for my husband, who watched me go through the struggle — countless doctors, years of labs and specialist appointments that led nowhere — and now that I've finally found something that works, he wants to start the GLP journey too. I'm also lucky to have a wonderful Dr. (endocrinologist) who monitors my labs and checks in every 6 months. He's especially eager about Reta's upcoming release. I'm still figuring out how I'll explain things to him at our twice-yearly appointments if I do end up trying it through the GM.
 
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