INTRO I’m a beginner looking for guidance

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herb7

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Intro

25M, 197 cm, 125 kg (roughly 25% BF). Right now my main aims are losing fat, getting my metabolism dialed in, and boosting everyday energy plus recovery.

I use long-acting TRT in the form of Nebido (1000 mg every 4–6 weeks), mostly to keep hormones steady. On top of that, I follow a structured peptide plan meant to help body composition, recovery, and mitochondrial function.

What I’m running now – began a few days back, except for Reta.

Retatrutide

titrated up to 4 mg each week, continuing to increase slowly

CJC-1295 (no DAC) + Ipamorelin

200 mcg before bed each night, fasted

SS-31

4 mg per day (set for a 4–6 week stretch)

→ MOTS-C wasn’t doing much for me, so this came first

MOTS-C

5 mg, 3x weekly (in the morning, paired with activity)

→ to follow the SS-31 phase

Epithalon

500 mcg per day, for 2-3 weeks (still deciding)



Melanotan I (optional)

200 mcg per day

KLOW (TB/BPC/GHK/KPV blend)

2,5mg 500mcg 500mcg 500mcg daily/ possibly 5 days on, 2 days off

Supplements

  • Vitamin D3 + K2 (10.000-30.000 IU per day)
  • Omega-3
  • Magnesium
  • Zinc 25 or 50 mg per day
  • B-complex
  • Beef liver

I’m also paying attention to electrolytes because of Reta + my diet.

Goals

  • Bring body fat down to ~10–15%
  • Keep or build muscle mass
  • Raise daily energy and cut down fatigue
  • Get sleep and recovery dialed in

- Deal with fatigue, particularly after exertion / after sex THIS ONE MATTERS A LOT - I have no idea why this keeps happening to me.

Notes / Observations

  • Energy goes up and down, especially while in a calorie deficit
  • Clear fatigue following sexual activity, gets better with a long rest - 2-3 weeks
  • Barely any reaction to MOTS-C at 5 mg, so now on SS-31


Why I’m here

I want to fine-tune this setup, get a better grasp on these fatigue patterns, and make everything more efficient without losing sight of long-term health.

Happy to hear thoughts on energy, recovery, and whether this is sustainable.
 
herb7 said:

Intro

25M, 197 cm, 125 kg (roughly 25% BF). Right now my main aims are losing fat, getting my metabolism dialed in, and boosting everyday energy plus recovery.

I use long-acting TRT in the form of Nebido (1000 mg every 4–6 weeks), mostly to keep hormones steady. On top of that, I follow a structured peptide plan meant to help body composition, recovery, and mitochondrial function.

What I’m running now – began a few days back, except for Reta.

Retatrutide

titrated up to 4 mg each week, continuing to increase slowly

CJC-1295 (no DAC) + Ipamorelin

200 mcg before bed each night, fasted

SS-31

4 mg per day (set for a 4–6 week stretch)

→ MOTS-C wasn’t doing much for me, so this came first

MOTS-C

5 mg, 3x weekly (in the morning, paired with activity)

→ to follow the SS-31 phase

Epithalon

500 mcg per day, for 2-3 weeks (still deciding)



Melanotan I (optional)

200 mcg per day

KLOW (TB/BPC/GHK/KPV blend)

2,5mg 500mcg 500mcg 500mcg daily/ possibly 5 days on, 2 days off

Supplements

  • Vitamin D3 + K2 (10.000-30.000 IU per day)
  • Omega-3
  • Magnesium
  • Zinc 25 or 50 mg per day
  • B-complex
  • Beef liver

I’m also paying attention to electrolytes because of Reta + my diet.

Goals

  • Bring body fat down to ~10–15%
  • Keep or build muscle mass
  • Raise daily energy and cut down fatigue
  • Get sleep and recovery dialed in

- Deal with fatigue, particularly after exertion / after sex THIS ONE MATTERS A LOT - I have no idea why this keeps happening to me.

Notes / Observations

  • Energy goes up and down, especially while in a calorie deficit
  • Clear fatigue following sexual activity, gets better with a long rest - 2-3 weeks
  • Barely any reaction to MOTS-C at 5 mg, so now on SS-31


Why I’m here

I want to fine-tune this setup, get a better grasp on these fatigue patterns, and make everything more efficient without losing sight of long-term health.

Happy to hear thoughts on energy, recovery, and whether this is sustainable.
Click to expand...
It's clear you've put in the effort to research this properly.

Based on what I've read, nothing stands out as a problem.

That said, I recently came across a YouTube clip featuring a doctor who had just returned from a peptide conference. The discussion there touched on peptides such as Mots-C, and the takeaway was that daily micro-dosing (1mg-2.5mg) may work better than taking it 3x/wk.

If anyone here has firsthand experience with Mots-C, I'd really appreciate hearing about it.
 
CharlieBrown said:


Good to see you've done your homework/research.

Everything looks good from the research I have done as well.

However, I just watched a video on YouTube with a Dr. that just recently went to a peptide conference and they discussed certain peptides like Mots-C where it is more beneficial to micro-dose (1mg-2.5mg) every day as appose to 3x/wk.

I'm hoping someone with Mots-C experience can share some info.

Click to expand...
Click to expand...

Not long ago I saw a claim that MOT-c might trigger anaphylaxis or a similar reaction. I still need to dig deeper into that, since I currently have 10 vials of it sitting unused.
 
herb7 said:

Intro

25M, 197 cm, 125 kg (roughly 25% BF). Right now my main aims are losing fat, getting my metabolism dialed in, and boosting everyday energy plus recovery.

I use long-acting TRT in the form of Nebido (1000 mg every 4–6 weeks), mostly to keep hormones steady. On top of that, I follow a structured peptide plan meant to help body composition, recovery, and mitochondrial function.

What I’m running now – began a few days back, except for Reta.

Retatrutide

titrated up to 4 mg each week, continuing to increase slowly

CJC-1295 (no DAC) + Ipamorelin

200 mcg before bed each night, fasted

SS-31

4 mg per day (set for a 4–6 week stretch)

→ MOTS-C wasn’t doing much for me, so this came first

MOTS-C

5 mg, 3x weekly (in the morning, paired with activity)

→ to follow the SS-31 phase

Epithalon

500 mcg per day, for 2-3 weeks (still deciding)



Melanotan I (optional)

200 mcg per day

KLOW (TB/BPC/GHK/KPV blend)

2,5mg 500mcg 500mcg 500mcg daily/ possibly 5 days on, 2 days off

Supplements

  • Vitamin D3 + K2 (10.000-30.000 IU per day)
  • Omega-3
  • Magnesium
  • Zinc 25 or 50 mg per day
  • B-complex
  • Beef liver

I’m also paying attention to electrolytes because of Reta + my diet.

Goals

  • Bring body fat down to ~10–15%
  • Keep or build muscle mass
  • Raise daily energy and cut down fatigue
  • Get sleep and recovery dialed in

- Deal with fatigue, particularly after exertion / after sex THIS ONE MATTERS A LOT - I have no idea why this keeps happening to me.

Notes / Observations

  • Energy goes up and down, especially while in a calorie deficit
  • Clear fatigue following sexual activity, gets better with a long rest - 2-3 weeks
  • Barely any reaction to MOTS-C at 5 mg, so now on SS-31


Why I’m here

I want to fine-tune this setup, get a better grasp on these fatigue patterns, and make everything more efficient without losing sight of long-term health.

Happy to hear thoughts on energy, recovery, and whether this is sustainable.
Click to expand...
Hi Herb, glad to have you here!

Warm regards,

Danger1212
 
itsapinthing said:


I recently came across something that said the MOT-c can cause anaphylaxis or something like that. I have to read into it more because I'm sitting on 10 vials of it

Click to expand...
Click to expand...
Anaphylactic shock is a possible reaction, and the risk is higher when the shot goes into muscle. From what I remember, VigorousSteve covers this topic on YouTube pretty thoroughly.

Canada Post is scheduled to bring me a 40mg kit on Monday.

My plan is to inject 1mg into the upper glutes, 1 inch under the waistline, rather than into the belly. I’ll use a 30g - 1/2 inch needle, going in at a 45 degree angle.

Assuming there are no problems, the next dose I attempt will be 2.5mg.

I’m wishing you a smooth experience, and once you’ve done your first pin, please share an update.
 
CharlieBrown said:


It can cause an anaphylaxis shock, especially if injection IM. I believe VigorousSteve on YouTube explains it quite well.

I have a 40mg kit arriving Monday with Canada Post.

I will pin 1mg in the upper glutes, 1 inch below the waist line, as appose to the abdomen area with a 30g - 1/2 inch needle at a 45 degree angle.

If all goes well, I will try 2.5mg next time.

I hope it goes well for you and please post after your first pin.

Click to expand...
Click to expand...
Hold on, you’re pinning MotsC intramuscularly?
 
herb7 said:


Wait you inject MotsC IM?

Click to expand...
Click to expand...
Not me.

VigorousSteve over on YouTube, though, did it unintentionally, and he describes what the experience was like.

Mine is supposed to arrive today. My plan is 1mg into the upper glute, 1" under the waist line.
 
CharlieBrown said:


It can cause an anaphylaxis shock, especially if injection IM. I believe VigorousSteve on YouTube explains it quite well.

I have a 40mg kit arriving Monday with Canada Post.

I will pin 1mg in the upper glutes, 1 inch below the waist line, as appose to the abdomen area with a 30g - 1/2 inch needle at a 45 degree angle.

If all goes well, I will try 2.5mg next time.

I hope it goes well for you and please post after your first pin.

Click to expand...
Click to expand...
Why that exact? Seems oddly precise.

And what makes you skip IN in favor of IM? I keep seeing folks mention IN, though I'm unsure whether it works as well or affects the mucosal membrane at all

EDIT: Sorry - I mixed up IM with plain "injecting". Those aren't the same thing; IM goes into muscle while SubQ goes into fat. SubQ is what you're doing. Got it now. Cheers
 
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