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Nunu-Nudie-Rudie

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Hey everyone,

Ally here. My time with glp1 medication adds up to roughly 18 months, with breaks in between. I dropped 25kgs, but 2/3 of that came back, so I have switched over to Retatrutide. The experience has been great up to now.

I want to get to know others, find out what approaches you all take to get the most out of your results, and hear how you support your weight loss journey from a health perspective too.

Looking forward to building new connections and picking up a lot!
 
Yep, with GLPs the problem boils down to "once on, always on". That said, studies are beginning to emerge around tapering at the end rather than quitting abruptly.

Even so, oral versions intended for "maintenance" dosing are far along in development and should hit the market broadly before long. I just caught the "on the pen" podcast, and they pointed out that the oral dose is actually TEN TIMES higher since merely 1% makes it through. The human body can be strange like that.
 
Nunu-Nudie-Rudie said:

¡Vaya, me encantaría escuchar ese podcast! Gracias por contestar
Searching "On the Pen" over on YT will bring up his channel. During his latest "one month off GLP-1" live show (not the podcast, my bad), around the 37-38m mark, the oral versions came up.
 
nighthawk98 said:

Yep, with GLPs the problem boils down to "once on, always on". That said, studies are beginning to emerge around tapering at the end rather than quitting abruptly.

Even so, oral versions intended for "maintenance" dosing are far along in development and should hit the market broadly before long. I just caught the "on the pen" podcast, and they pointed out that the oral dose is actually TEN TIMES higher since merely 1% makes it through. The human body can be strange like that.
Is that due to the peptides getting broken down in the stomach, or something like that?

I'll give the podcast a listen later, it sounds interesting.
 
Willem89 said:

nighthawk98 said:

Yep, with GLPs the problem boils down to "once on, always on". That said, studies are beginning to emerge around tapering at the end rather than quitting abruptly.

Even so, oral versions intended for "maintenance" dosing are far along in development and should hit the market broadly before long. I just caught the "on the pen" podcast, and they pointed out that the oral dose is actually TEN TIMES higher since merely 1% makes it through. The human body can be strange like that.
Is that due to the peptides getting broken down in the stomach, or something like that?

I'll give the podcast a listen later, it sounds interesting.
Right. According to what they said, just 1 percent makes it through. That's crazy, though it makes sense — our stomachs contain hydrochloric acid, after all. They mentioned that because of this, in India injections are going to cost less than the pills. I was thinking "Oh, a pill would be my preference anyway" until it hit me that I am HORRIBLE at remembering to take my medications. A once per week injection is hard to miss though. When you take an injection you REMEMBER you did so.
 
Nunu-Nudie-Rudie said:

Hey everyone,

Ally here. My time with glp1 medication adds up to roughly 18 months, with breaks in between. I dropped 25kgs, but 2/3 of that came back, so I have switched over to Retatrutide. The experience has been great up to now.

I want to get to know others, find out what approaches you all take to get the most out of your results, and hear how you support your weight loss journey from a health perspective too.

Looking forward to building new connections and picking up a lot!
Hey Ally, great to have you here!

I'm another person navigating the GLP‑1 path, so I figured I'd say hello too. About four months back I started tirzepatide, currently at 5 mg weekly, and during the last month I've added 1 mg of Reta per week on top of that. My reasoning is pretty simple: I've got roughly equal supplies of both compounds that will last me a good while, and my system tends to do better when I move gradually. Sticking to consistent ratios makes it easier to tell when an increase is warranted, while keeping things within a level that doesn't feel overwhelming or hard to maintain.

There were also stretches in my past where I dropped a lot of weight quickly, only to put much of it back on, and that experience made me step back and reconsider my approach so I could be more deliberate about what actually serves my body over the long haul. Hearing that Retatrutide has been working so well for you is genuinely motivating.

My reasons for being here match yours—meeting people, picking up what's working for others, and paying attention to the health side of all this rather than just the number on the scale. Excited to swap stories and pick up things from everyone.
 
AcadiaPeptides said:

Nunu-Nudie-Rudie said:

Hey everyone,

Ally here. My time with glp1 medication adds up to roughly 18 months, with breaks in between. I dropped 25kgs, but 2/3 of that came back, so I have switched over to Retatrutide. The experience has been great up to now.

I want to get to know others, find out what approaches you all take to get the most out of your results, and hear how you support your weight loss journey from a health perspective too.

Looking forward to building new connections and picking up a lot!
Hey Ally, great to have you here!

I'm another person navigating the GLP‑1 path, so I figured I'd say hello too. About four months back I started tirzepatide, currently at 5 mg weekly, and during the last month I've added 1 mg of Reta per week on top of that. My reasoning is pretty simple: I've got roughly equal supplies of both compounds that will last me a good while, and my system tends to do better when I move gradually. Sticking to consistent ratios makes it easier to tell when an increase is warranted, while keeping things within a level that doesn't feel overwhelming or hard to maintain.

There were also stretches in my past where I dropped a lot of weight quickly, only to put much of it back on, and that experience made me step back and reconsider my approach so I could be more deliberate about what actually serves my body over the long haul. Hearing that Retatrutide has been working so well for you is genuinely motivating.

My reasons for being here match yours—meeting people, picking up what's working for others, and paying attention to the health side of all this rather than just the number on the scale. Excited to swap stories and pick up things from everyone.
Great to hear back from you! I may explore stacking as well, to figure out what could help. The Reta I recently picked up from a seller here seems somewhat sketchy — right now I suspect my ADHD meds are carrying most of the appetite suppression, so I'll need to set aside funds and test a batch from a different supplier, I think.
 
nighthawk98 said:

Willem89 said:

nighthawk98 said:

Yep, with GLPs the problem boils down to "once on, always on". That said, studies are beginning to emerge around tapering at the end rather than quitting abruptly.

Even so, oral versions intended for "maintenance" dosing are far along in development and should hit the market broadly before long. I just caught the "on the pen" podcast, and they pointed out that the oral dose is actually TEN TIMES higher since merely 1% makes it through. The human body can be strange like that.
Is that due to the peptides getting broken down in the stomach, or something like that?

I'll give the podcast a listen later, it sounds interesting.
Right. According to what they said, just 1 percent makes it through. That's crazy, though it makes sense — our stomachs contain hydrochloric acid, after all. They mentioned that because of this, in India injections are going to cost less than the pills. I was thinking "Oh, a pill would be my preference anyway" until it hit me that I am HORRIBLE at remembering to take my medications. A once per week injection is hard to miss though. When you take an injection you REMEMBER you did so.
That is really interesting! Quite a difference from the stimulant pills that were handed out for weight loss back in the 90's & 00's
 
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