Hey all!
I'm living with type 2 diabetes. It was diagnosed in 2018, at a point when my blood sugar sat near 30 mmol/L and my weight was roughly 150 kg (330 lbs).
After that diagnosis I threw everything at losing weight — keto, working out, tracking calories, whatever you can think of. Progress was slow and hard, but in the end it started to happen.
Semaglutide entered the picture in December 2024. Back then I weighed about 118 kg (260 lbs), and by this spring I had gotten down to roughly 96 kg (212 lbs).
Then things went sideways: a serious flare-up of bipolar depression, triggered by major work-related problems. Across roughly 2 months of severe depression I put on about 15 kg (33 lbs). Right now I'm focused on getting my medications adjusted again, and at the same time trying to bring my weight back down.
These days semaglutide no longer feels like it's doing enough for me, which is why I began researching retatrutide. I've already located a source, but I want to hear from people with similar stories before I make any move.
What I'd most like to hear about:
— how semaglutide and other drugs in this class have worked out for you;
— if anyone here has used retatrutide, and what the results and side effects looked like;
— which other peptides or weight-loss drugs are being talked about or used right now;
— and whether anyone has succeeded in keeping weight off over the long term.
There's a second concern that weighs on me as much as the weight itself.
For the past couple of years I've been trying to keep myself physically active — cycling, walking, strength training with light weights, pull-ups, push-ups, squats, and so on. But during the last 3 months my physical performance has dropped off noticeably.
As the bipolar depression has worsened, training has gotten a lot harder, and I have the feeling that I'm losing muscle mass.
So I'd also like to hear from anyone who has dealt with muscle loss while shedding weight, while on GLP-1 drugs or similar medications, or during a depressive episode.
Any personal experiences, useful threads, or solid research you can point me to would mean a lot. My goal is to understand this beyond just weight loss — how to hold onto muscle mass and stay physically fit.
my blood sugar has stayed controlled and within the normal range for the last six years.
I'm living with type 2 diabetes. It was diagnosed in 2018, at a point when my blood sugar sat near 30 mmol/L and my weight was roughly 150 kg (330 lbs).
After that diagnosis I threw everything at losing weight — keto, working out, tracking calories, whatever you can think of. Progress was slow and hard, but in the end it started to happen.
Semaglutide entered the picture in December 2024. Back then I weighed about 118 kg (260 lbs), and by this spring I had gotten down to roughly 96 kg (212 lbs).
Then things went sideways: a serious flare-up of bipolar depression, triggered by major work-related problems. Across roughly 2 months of severe depression I put on about 15 kg (33 lbs). Right now I'm focused on getting my medications adjusted again, and at the same time trying to bring my weight back down.
These days semaglutide no longer feels like it's doing enough for me, which is why I began researching retatrutide. I've already located a source, but I want to hear from people with similar stories before I make any move.
What I'd most like to hear about:
— how semaglutide and other drugs in this class have worked out for you;
— if anyone here has used retatrutide, and what the results and side effects looked like;
— which other peptides or weight-loss drugs are being talked about or used right now;
— and whether anyone has succeeded in keeping weight off over the long term.
There's a second concern that weighs on me as much as the weight itself.
For the past couple of years I've been trying to keep myself physically active — cycling, walking, strength training with light weights, pull-ups, push-ups, squats, and so on. But during the last 3 months my physical performance has dropped off noticeably.
As the bipolar depression has worsened, training has gotten a lot harder, and I have the feeling that I'm losing muscle mass.
So I'd also like to hear from anyone who has dealt with muscle loss while shedding weight, while on GLP-1 drugs or similar medications, or during a depressive episode.
Any personal experiences, useful threads, or solid research you can point me to would mean a lot. My goal is to understand this beyond just weight loss — how to hold onto muscle mass and stay physically fit.
my blood sugar has stayed controlled and within the normal range for the last six years.