GLP 1 weight loss and skin tightening with GHK CU

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teetee07

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I know that loose skin can turn into a problem for certain people while they are losing weight. From what I have looked into, I have come across claims and heard people say that putting GHK CU into their routine has contributed to firmer skin. Has anyone in this community seen anything like that themselves? Would GHK CU be something worth exploring for skin concerns? Any input would be great. Thanks folks 🙂
 
teetee07 said:

I know that loose skin can turn into a problem for certain people while they are losing weight. From what I have looked into, I have come across claims and heard people say that putting GHK CU into their routine has contributed to firmer skin. Has anyone in this community seen anything like that themselves? Would GHK CU be something worth exploring for skin concerns? Any input would be great. Thanks folks 🙂
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My weight loss journey began 6 months back, and I've incorporated ghk throughout that entire period. I've dropped 88lbs without any sagging skin. So I do believe it's effective.
 
There are many factors at play, in my view. One that matters a lot is age. With the added boost from GHK-cu, younger skin tends to bounce back more effectively.

As for me, I'm middle aged, have just a modest amount of weight left to shed, and have spent only 1 month on a GLP1 plus GLOW. So far there's nothing to share, though I'm hoping to move over to KPV and GHK-cu alone before long, and perhaps once I reach my target weight, the slight looseness around my belly will have resolved.
 
Nopenada said:

There are many factors at play, in my view. One that matters a lot is age. With the added boost from GHK-cu, younger skin tends to bounce back more effectively.

As for me, I'm middle aged, have just a modest amount of weight left to shed, and have spent only 1 month on a GLP1 plus GLOW. So far there's nothing to share, though I'm hoping to move over to KPV and GHK-cu alone before long, and perhaps once I reach my target weight, the slight looseness around my belly will have resolved.
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Maybe, but I'm closing in on 60 and it's worked really well for me.
 
What would actually help us out? If a pair of very obese identical twins stumbled onto this site, got hyped about tirz or reta, started using them, and then just ONE of them went ahead with Klow while the other shrugged and passed. To be clear, I'm not advocating for treating people like lab rats, and I'm definitely not saying we should intentionally recruit twins just so we can finally get a few anecdotal reports about klow and loose skin that go beyond "trust me bro". Honestly, I suspect that even floating the idea to a newcomer might come across as borderline nazi-adjacent, and I have zero interest in that.

What I am saying is this: if any twins ever post a welcome thread, I intend to be extremely, EXTREMELY kind to them. 😀
 
CNCCurrency said:

teetee07 said:

I know that loose skin can turn into a problem for certain people while they are losing weight. From what I have looked into, I have come across claims and heard people say that putting GHK CU into their routine has contributed to firmer skin. Has anyone in this community seen anything like that themselves? Would GHK CU be something worth exploring for skin concerns? Any input would be great. Thanks folks 🙂
Click to expand...
My weight loss journey began 6 months back, and I've incorporated ghk throughout that entire period. I've dropped 88lbs without any sagging skin. So I do believe it's effective.
Click to expand...
Wow, that's amazing. Great job on what you've achieved up to now 🙌🏽
 

Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data - PMC



The human peptide GHK (glycyl-l-histidyl-l-lysine) has multiple biological actions, all of which, according to our current knowledge, appear to be health positive. It stimulates blood vessel and nerve outgrowth, increases collagen, elastin, and ...

4d13c41cbc0409fb932089618e379d69d6e07846fc324487242c1d77d1bad140.png



pmc.ncbi.nlm.nih.gov

Tirz has taken me from a BMI of 40.0 down to 33.7, which means I've dropped close to 40 lbs over 2 months. What I'm not loving is that my neck is beginning to show loose skin. After reading that NIH article, I decided to give GHK-Cu a try and placed an order last night. I also picked up a GHK-Cu face cream and a micro-roller.
 
Honestly, finding out about GHK-Cu earlier would have been great. This marks my 2nd time dropping over 100 lbs, and the skin under my chin is really sagging. Being 39 makes it feel awful, particularly since the rest of my face is firm. I'm going to order some and come back to this sub with an update if things get better.
 
WriteYourWay said:

Honestly, finding out about GHK-Cu earlier would have been great. This marks my 2nd time dropping over 100 lbs, and the skin under my chin is really sagging. Being 39 makes it feel awful, particularly since the rest of my face is firm. I'm going to order some and come back to this sub with an update if things get better.
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This isn't an instant solution. It delivers a spike and then fades, with a half-life measured in 3 or 4 minutes and clearance taking roughly 20 minutes. The effects build up over time, yet it does boost collagen through that brief surge.
 
I'm close to finishing my initial 2 month run of GHK-Cu. As far as tightening skin goes, I can't say much yet — I'd already dropped roughly 55 lbs by the time I learned about it, and I'm now around 72.

However, there is one change I've picked up on: I have a genetic condition, Ehlers Danlos Syndrome, which impacts connective tissue and collagen in the body. My fingernails have always been super brittle. They break apart very easily, so I trim them as near to the quick as possible; otherwise they'll crack lengthwise down INTO the nail bed, which is miserable. Here's what happened: roughly 2 weeks after starting the cycle, I realized my nails felt tougher. I'd neglected to trim them and they weren't breaking! Since then just 1 split has happened, from hitting my finger against something hard.

I still keep my nails fairly short, and they're not at the strength of someone without EDS, but compared with before I began GHK-Cu they are WAY improved.

That's what I've got so far.
 
After dropping 79kg I'm left with a great deal of sagging skin, so clearly the reason must be that I never took Glow as a preventive measure. (Honestly, I'm glad to be dealing with this particular issue.)

From everything I've come across or grasp about human physiology, a peptide simply isn't capable of changing this. The bands of elastin and collagen fibrous tissue running through the subcutaneous fat, which anchor skin to the tissues beneath, have been stretched out over a long period. Any of them still holding tension will contract in size after weight comes off, but once they've lengthened I simply can't accept that they'll remodel. It's not impossible that localized treatments might do something, yet achieving uniform results with them would likely be unachievable.

If peptides were driving connective tissue growth on that scale (throughout the entire body beneath the skin, and enough to firm up sagging skin), I'd be deeply concerned about them spurring fibrous tissue growth in other places too, such as the heart, lungs or kidneys, leading to severe organ dysfunction.

Naturally, absent an enormous clinical trial there's no way to ever know whether it worked. If you reach the end without loose skin, it will appear as though it worked. I'd be genuinely astonished if you could placebo-effect your way into subcutaneous tissue remodeling.
 
At this point, my age and the amount of weight I've dropped mean surgery is the only real solution for the leftover skin. Spanx and I are bonded for life.

Even so, GHKcu is part of my routine. The cosmetic improvements to my skin are great, but it brings plenty of other advantages beyond appearance. I'm a fan and plan to keep it stocked permanently.
 
lessthanhalf said:

After dropping 79kg I'm left with a great deal of sagging skin, so clearly the reason must be that I never took Glow as a preventive measure. (Honestly, I'm glad to be dealing with this particular issue.)

From everything I've come across or grasp about human physiology, a peptide simply isn't capable of changing this. The bands of elastin and collagen fibrous tissue running through the subcutaneous fat, which anchor skin to the tissues beneath, have been stretched out over a long period. Any of them still holding tension will contract in size after weight comes off, but once they've lengthened I simply can't accept that they'll remodel. It's not impossible that localized treatments might do something, yet achieving uniform results with them would likely be unachievable.

If peptides were driving connective tissue growth on that scale (throughout the entire body beneath the skin, and enough to firm up sagging skin), I'd be deeply concerned about them spurring fibrous tissue growth in other places too, such as the heart, lungs or kidneys, leading to severe organ dysfunction.

Naturally, absent an enormous clinical trial there's no way to ever know whether it worked. If you reach the end without loose skin, it will appear as though it worked. I'd be genuinely astonished if you could placebo-effect your way into subcutaneous tissue remodeling.
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That idea about organ growth seems a little off to me, and I doubt it holds up. Can you point me to any research backing it? The only thing I've ever come across that caused organ growth was hgh at high doses.
 
My point was not organ growth. It was fibrous tissue growth inside those organs. If it promotes fibrous tissue growth, chances are it is doing so throughout the body. These blends are marketed for soft tissue injuries, not only for skin. For instance, fibrous tissue accumulating in heart muscle leads to heart failure. My reasoning: if it truly performs as claimed, then it is hazardous. My suspicion is that it breaks down too fast to have much effect? (since no human studies exist, nor even animal studies on these blends)
 
lessthanhalf said:

My point was not organ growth. It was fibrous tissue growth inside those organs. If it promotes fibrous tissue growth, chances are it is doing so throughout the body. These blends are marketed for soft tissue injuries, not only for skin. For instance, fibrous tissue accumulating in heart muscle leads to heart failure. My reasoning: if it truly performs as claimed, then it is hazardous. My suspicion is that it breaks down too fast to have much effect? (since no human studies exist, nor even animal studies on these blends)
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That is basically splitting hairs, so where is the research backing that theory? If it is only your own theory, then that is like shouting fire in a crowded movie theater
 
teetee07 said:

I know that loose skin can turn into a problem for certain people while they are losing weight. From what I have looked into, I have come across claims and heard people say that putting GHK CU into their routine has contributed to firmer skin. Has anyone in this community seen anything like that themselves? Would GHK CU be something worth exploring for skin concerns? Any input would be great. Thanks folks 🙂
Click to expand...
When I began peptides, my weight was 334 and my age was 54. KLOW is something I take every day, and I reckon it won't do any harm to the situation. Avoiding sagging skin entirely doesn't seem likely to me; the only thing I can do is hope it's cutting down on whatever I do end up with.
 
Whether GHK-CU would reduce skin looseness during weight loss is tough to determine. Still, from my perspective, it doesn't cost much and might help limit loose skin, plus it offers other advantages. I'd say give it a shot!

I've been taking glow or klow together with a GLP 1, and I just placed an order for some GHK-CU to use by itself during the breaks between klow cycles.
 
Alikron13 said:

I'm close to finishing my initial 2 month run of GHK-Cu. As far as tightening skin goes, I can't say much yet — I'd already dropped roughly 55 lbs by the time I learned about it, and I'm now around 72.

However, there is one change I've picked up on: I have a genetic condition, Ehlers Danlos Syndrome, which impacts connective tissue and collagen in the body. My fingernails have always been super brittle. They break apart very easily, so I trim them as near to the quick as possible; otherwise they'll crack lengthwise down INTO the nail bed, which is miserable. Here's what happened: roughly 2 weeks after starting the cycle, I realized my nails felt tougher. I'd neglected to trim them and they weren't breaking! Since then just 1 split has happened, from hitting my finger against something hard.

I still keep my nails fairly short, and they're not at the strength of someone without EDS, but compared with before I began GHK-Cu they are WAY improved.

That's what I've got so far.
Click to expand...
EDS is something I deal with as well. I'm eager to see my nails get better! They were in decent shape before, but after reaching my late 30s, ridges have appeared.
 
Alikron13 said:

I'm close to finishing my initial 2 month run of GHK-Cu. As far as tightening skin goes, I can't say much yet — I'd already dropped roughly 55 lbs by the time I learned about it, and I'm now around 72.

However, there is one change I've picked up on: I have a genetic condition, Ehlers Danlos Syndrome, which impacts connective tissue and collagen in the body. My fingernails have always been super brittle. They break apart very easily, so I trim them as near to the quick as possible; otherwise they'll crack lengthwise down INTO the nail bed, which is miserable. Here's what happened: roughly 2 weeks after starting the cycle, I realized my nails felt tougher. I'd neglected to trim them and they weren't breaking! Since then just 1 split has happened, from hitting my finger against something hard.

I still keep my nails fairly short, and they're not at the strength of someone without EDS, but compared with before I began GHK-Cu they are WAY improved.

That's what I've got so far.
Click to expand...

GHKcu cannot possibly change the end of your fingernails within 2 months.
 
CNCCurrency said:

teetee07 said:

I know that loose skin can turn into a problem for certain people while they are losing weight. From what I have looked into, I have come across claims and heard people say that putting GHK CU into their routine has contributed to firmer skin. Has anyone in this community seen anything like that themselves? Would GHK CU be something worth exploring for skin concerns? Any input would be great. Thanks folks 🙂
Click to expand...
My weight loss journey began 6 months back, and I've incorporated ghk throughout that entire period. I've dropped 88lbs without any sagging skin. So I do believe it's effective.
Click to expand...
Are you doing this as a daily injection?
 
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