Genetic tests

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lastresort

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Has anyone here gone through medical genetic counseling for their weight problems?

For me: low T, Hashimoto, and a fatty liver. Neither Ozempic nor zepbound made any difference. The only one that does anything at all — retatrutide — lets me lose weight in a normal way, but the changes aren't as dramatic as what other people here describe.

My endos referred me for medical genetic testing in July...I've since figured out how to get retatrutide for less money, but honestly, if an exact cause could be pinned down, I'd want to treat that first. Thoughts?
 
lastresort said:

Has anyone here gone through medical genetic counseling for their weight problems?

For me: low T, Hashimoto, and a fatty liver. Neither Ozempic nor zepbound made any difference. The only one that does anything at all — retatrutide — lets me lose weight in a normal way, but the changes aren't as dramatic as what other people here describe.

My endos referred me for medical genetic testing in July...I've since figured out how to get retatrutide for less money, but honestly, if an exact cause could be pinned down, I'd want to treat that first. Thoughts?
Click to expand...
??? Dude, do you mean why GLP isn't working as it should?
 
lastresort said:

Has anyone here gone through medical genetic counseling for their weight problems?

For me: low T, Hashimoto, and a fatty liver. Neither Ozempic nor zepbound made any difference. The only one that does anything at all — retatrutide — lets me lose weight in a normal way, but the changes aren't as dramatic as what other people here describe.

My endos referred me for medical genetic testing in July...I've since figured out how to get retatrutide for less money, but honestly, if an exact cause could be pinned down, I'd want to treat that first. Thoughts?
Click to expand...

An exact cause of what, though? Obesity?

Where genetic testing earns its keep is early-onset or extreme obesity, when a single gene is suspected. With ordinary adult obesity there are certainly genetic contributions, but they are diffuse and likely spread across many genes, so testing changes neither the treatment nor the interventions. And there is nothing to "treat". No gene therapy for obesity currently exists. So even if your genes revealed the "cause" of your obesity, you could not act on it first.

To be clear, genetic testing has my full support at 100% and I have had some done for other conditions of mine, but even there it comes down to managing the related conditions.
 
It has been shown that a GLP drug's effects can be overcome by overeating, if that is what someone chooses to do. When used properly, the medication supports improved decisions, which in turn makes effective weight loss possible. Should you assume the drug will handle everything on its own, results will probably fall short. Track your calories. Figure out what your maintenance calories are. Consume fewer calories than that. A GLP makes this less difficult than doing it alone, yet the fundamentals do not change.
 
Interesting. Do report back on what your doctors are trying to identify, what the genetic testing turns up, and what game plan comes out of it.
 
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