Do you account for overages?

WLBLD

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When you work out your dose, do you factor in the tested overages? For example, if a 30mg vial tests at roughly 34mg, do you still calculate based on the label, or do you include that extra 4mg or whatever the difference is?
 
When I mix, I go by the average from the test reports and treat that as the real amount in the vial. Plenty of people skip this, arguing that the difference is just a small percentage of error. That may be so, but when the data is right there, why ignore it? Say I have R20 that came back at 23 mg — reaching a 10 mg/mL concentration means adding 2.3 mL instead of 2 mL, which is no harder. With a GLP especially, I really aim for maximum accuracy.
 
Normally I ignore it and treat the extra as a cushion against degradation. That said, I just received some Tirz 60mg that came back at 72mg. That feels like a lot of overfill, so I'm not sure what to do with that kit. Had the overage been 8mg or less, I wouldn't worry much — unless I were testing something completely new.
 
Dos-Dox said:

When I mix, I go by the average from the test reports and treat that as the real amount in the vial. Plenty of people skip this, arguing that the difference is just a small percentage of error. That may be so, but when the data is right there, why ignore it? Say I have R20 that came back at 23 mg — reaching a 10 mg/mL concentration means adding 2.3 mL instead of 2 mL, which is no harder. With a GLP especially, I really aim for maximum accuracy.
That's basically my approach too. My r 30 came back at 34 (I believe), so I added 3.4 ml, which lets me dose precisely.
 
Nope. Overfill has never factored into how I calculate a dose. That said, I prefer my peptides with a bit of a kick. Not quite the kick @Super Trips goes for, but still a little spicy. Small wonder I can't 💩💩💩

Anyway, just this morning I pinned some elora that tested at 13mg, which I mixed with 1mL of bac and then pinned 50 units. My previous dose was 5mg... but I thought, what's the point of dealing with odd fractions, and there's no time like now to titrate up 😂.
 
Dos-Dox said:

When I mix, I go by the average from the test reports and treat that as the real amount in the vial. Plenty of people skip this, arguing that the difference is just a small percentage of error. That may be so, but when the data is right there, why ignore it? Say I have R20 that came back at 23 mg — reaching a 10 mg/mL concentration means adding 2.3 mL instead of 2 mL, which is no harder. With a GLP especially, I really aim for maximum accuracy.
Listen, I dose by how it feels and by the tick marks on the syringe. None of that complicated milligram math. Sounds like another big pharma trick to me.
 
Yup! When the tested mass comes in 1mg or more above or below what's expected, I average it out and use that to set my reconstitution and the concentration I write on the label. For Selank testing at 10.3mg, I generally still treat it as 10.

Elora is different, though — with that one I always go by the average of the tested mass, because it's way too expensive for me to play games with! So if 10mg tests at 10.61mg, you bet I'm counting those 0.61mgs! 😂

(I had to work it out… @Grogu took 6.5mg…I can't do recon math in my head and it was bugging me!)
 
plant_lady said:

Normally I ignore it and treat the extra as a cushion against degradation. That said, I just received some Tirz 60mg that came back at 72mg. That feels like a lot of overfill, so I'm not sure what to do with that kit. Had the overage been 8mg or less, I wouldn't worry much — unless I were testing something completely new.
That's a big overage! You really got lucky with that batch. An amount that far above label is something I would certainly factor in.
 
Calm Logic said:

Listen, I dose by how it feels and by the tick marks on the syringe. None of that complicated milligram math. Sounds like another big pharma trick to me.

That takes me back to when I used to hang around Reddit's compound tirzepatide subreddit. People who were just starting out would frequently describe their dose in unitz. I'm on 30 unitz. 🙄

There's a saying that "The dose makes the poison" — though perhaps in this case it's "The unitz make the poison."
 
I once took part in a group test where one R30 came out at about 33mg while a different one measured 28. That means variation can exist even inside a single kit.
 
I base my routine on the averages from the test. So why not set the dosages up to be as consistent as possible from the start? It doesn't require any additional effort, and the payoff is consistency.
 
SamsHere said:

I once took part in a group test where one R30 came out at about 33mg while a different one measured 28. That means variation can exist even inside a single kit.
That kind of spread is possible, but it's quite an extreme variation and could point to more than one batch or source.

To get back to the original question, though: I treat the label as gospel, 30 is 30.

After filtering, and possibly after some aging, everything tends to even out pretty close.

Sure, maybe that 28 covers a rough week and the 33 calls for more water and fiber; but odds are you won't notice a difference, at least I haven't across more than 2 years of pinning.
 
I only adjust the BAC when the dose is 5mg or higher. Shortages get the same treatment from me. So far, I've run into just one.
 
Grogu said:

That takes me back to when I used to hang around Reddit's compound tirzepatide subreddit. People who were just starting out would frequently describe their dose in unitz. I'm on 30 unitz. 🙄

There's a saying that "The dose makes the poison" — though perhaps in this case it's "The unitz make the poison."

Fair points, for sure. That's exactly why I stick with 30-unit syringes — no issue anymore.
 
WLBLD said:

That's a big overage! You really got lucky with that batch. An amount that far above label is something I would certainly factor in.
Indeed, the overfill was pretty significant. In hindsight, I regret not grabbing more than 1 kit. That batch has since completely sold out 😣.
 
After roughly 24 hours following a pin, I (believe I) can sense whether a batch runs overfilled or underfilled. Based on that, I adjust my later pins. If a pin feels weak, I may add a 0.2mg pin 48 hours afterward to compensate for an underfill.
 
WLBLD said:

When you work out your dose, do you factor in the tested overages? For example, if a 30mg vial tests at roughly 34mg, do you still calculate based on the label, or do you include that extra 4mg or whatever the difference is?
Yes, each time — I simply enter it into the calculator.
 
Yes, I do. I add slightly more bac water, though only a little extra. This matters particularly since we typically don't pull out the full 100% from the vial.
 
yes.

most of what I've got stockpiled comes with at least 2 vial conformity, so I have a somewhat clearer picture of what's actually in there. I'm not like many folks on the forum who are fine with feeling a bit hungry for a day or two before the next dose — what worries me is getting violently sick and spending the night hugging the toilet because it's too strong. when I nail it (which is most of the time) the food noise is entirely gone, I still eat at normal intervals, I just can't put away as much as my former fat ass self could. it's really not difficult to plug it into the calculator, figure out the dose per unit, and work from there.

the tirz batch I'm currently using is 0.192mg per unit
 
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