Cycle off or not (GHK-CU)

Optimistic3

Optimistic3

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I have been taking GHK-CU since 5/15/26, and I’m already seeing noticeable improvements in lines I had on my neck, they are slowly disappearing. I also fractured my collarbone 3 weeks ago so have been taking wolverine blend as well. I have been trying to decide if I should cycle off GHK-cu for 2 weeks to 30 days or just continue taking. I’ve read different things about people saying it’s not necessary to cycle off and vice vs. I will say that I feel like the the Wolverine is really helping my injury as well, so do I continue to take it until I stop Wolverine then take the cycle break, thoughts??
 
I'm in the middle of a 12-week cycle of GHK-Cu as well. My understanding is that the reason for cycling off is too avoid too much copper buildup in the body, and not because of desensitization. I plan on cycling off for this reason although I suspect that copper buildup may be less of a concern the older we are.
 
I'm on month 3 of 2mg daily. I do not plan on cycling off as of now. I never got any sides from it and I'm over 50 so I'm going to roll with it, I will reassess later in the year after my next labs check.
 
I have no intention to cycle Cu. I've been daily since February. My changes are subtle, unlike @FarmgirlRebel (search for her post!). If I remember correctly, her results were realized in a 12-week cycle.
 
Angelique said:


I'm in the middle of a 12-week cycle of GHK-Cu as well. My understanding is that the reason for cycling off is too avoid too much copper buildup in the body, and not because of desensitization. I plan on cycling off for this reason although I suspect that copper buildup may be less of a concern the older we are.

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I have been taking zinc supplements in hope to offset this. But I agree I think it’s less of an issue the older we are
 
HereKittyKitty said:


I've heard the Zinc supplements are not necessary (effective) unless the PT has high Cu in their serum or has Wilson's Disease.

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If you want to keep your skin saggy after losing weight or if you want to go bald, no problemo, you don't need zinc.
 
SeaGypsy said:


I'm on month 3 of 2mg daily. I do not plan on cycling off as of now. I never got any sides from it and I'm over 50 so I'm going to roll with it, I will reassess later in the year after my next labs check.

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Why are you not cycling of, have you seen many benefits from it ? I'm only one week in to 2mg
 
Celtic said:


Why are you not cycling of, have you seen many benefits from it ? I'm only one week in to 2mg

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No need to cycle off, your body makes it naturally and production lessens with age. I have noticed skin, hair, and nails improving. Skin feels firmer, thicker. Hair has darkened and thickened, nails are ridiculous hard now. I love the stuff
 
I've been debating this exact topic with myself the last few days. I've been pinning 2mg of GHK-cu daily (with 1-1.5mg of KPV) since mid-March and I do finally see noticeable improvements. Fewer fine lines and skin seems to be almost filling in where there had been some sallow before.

I am of the age where this pep is noted as being most useful, and I take zinc daily as well. So it's really just a matter of determining if I keep going with no break, or potentially losing some of the gains by cycling off for the not yet (?) confirmed copper toxicity risk.
 
I just started pinning 1mg, 2x/day. I am psyched!!! Especially for skin elasticity.

I can tell y’all the placebo effect is real LOL! I’m only 2 days in, and I’m like “oooh, soft skin!” 🤣 It’s all in my mind of course, but looking forward to actual results. Already took a before pic of my face a la @FarmgirlRebel

Non Sequitur: My skin has improved dramatically after 5 months on tirz. Hyperpigmentation fading, clearer pores…I did not expect that at all. At this point I feel fine going out bare faced!
 
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