Cresol, anyone?

Chili777

Chili777

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A vendor's mazdutide was recently discovered on STG to contain cresol, which is a highly toxic antiseptic. That could only have entered during manufacturing. Cresol (or metacresol) does not appear among the inactive ingredients of the lyophilizing process.

The excipients for lyophilization are:

· Trometamol

· Mannitol

· Propylene glycol (for injection)

· Disodium edetate

· Dilute hydrochloric acid

· Sodium hydroxide

· Water for injections

Cresol is not present in any of them, nor do any of them contain it.

Comments:

"There should never be enough cresol to have a lab put this on a coa

Sry had it one time and gave out refunds

But this isn’t normal

You should get a refund if this is in your peps

This is trash pep

Do not use this throw it only"

Those around longer may recall SRY having the same problem last year (together with Paraben), and refunds were issued.

Everyone, stay cautious.
 
Chili777 said:

A vendor's mazdutide was recently discovered on STG to contain cresol, which is a highly toxic antiseptic. That could only have entered during manufacturing. Cresol (or metacresol) does not appear among the inactive ingredients of the lyophilizing process.

The excipients for lyophilization are:

· Trometamol

· Mannitol

· Propylene glycol (for injection)

· Disodium edetate

· Dilute hydrochloric acid

· Sodium hydroxide

· Water for injections

Cresol is not present in any of them, nor do any of them contain it.

Comments:

"There should never be enough cresol to have a lab put this on a coa

Sry had it one time and gave out refunds

But this isn’t normal

You should get a refund if this is in your peps

This is trash pep

Do not use this throw it only"

Those around longer may recall SRY having the same problem last year (together with Paraben), and refunds were issued.

Everyone, stay cautious.
Click to expand...

From what I remember, Jano's response mentioned that insulin commonly uses this as a preservative, unless I'm mixing that up.
 
Not every form of cresol is harmful. The report now includes m-cresol, a substance that serves as a preservative.
 
Chili777 said:

Habibibi said:

Not every form of cresol is harmful. The report now includes m-cresol, a substance that serves as a preservative.
Click to expand...
Can someone point me to that update? I haven't spotted Peter commenting in either of the STG chats.




m-Cresol - Hazardous Agents | Haz-Map



Haz-Map database entry with detailed information on the m-Cresol agent.

Image unavailable


www.haz-map.com
Click to expand...

Take another look at that COA

(link removed because the COA comes from a gb)

At 3-4mg/ml or below, m-cresol is acceptable.
 
Habibibi said:

Chili777 said:

Habibibi said:

Not every form of cresol is harmful. The report now includes m-cresol, a substance that serves as a preservative.
Click to expand...
Can someone point me to that update? I haven't spotted Peter commenting in either of the STG chats.




m-Cresol - Hazardous Agents | Haz-Map



Haz-Map database entry with detailed information on the m-Cresol agent.

Image unavailable


www.haz-map.com
Click to expand...

Take another look at that COA

(link removed because the COA comes from a gb)

At 3-4mg/ml or below, m-cresol is acceptable.
Click to expand...
Found over on Meso, in the Analytical Lab Testing thread about Cresol — attachment included. As a preservative it's a bad pick, and that goes double for GLPs. Insulin isn't a GLP.

On top of that, Peter's remark never says whether the stuff is good or bad, only that it shows up. And the peak tells you nothing about quantity, since that assay doesn't report it. In his write-up on the test he notes it isn't included among the impurities either. Same story as his Jeep endo test, which simply read 2306EU. He left it to others to decide if that was bad, and most landed on the right answer.
 
Chili777 said:

Habibibi said:

Chili777 said:

Habibibi said:

Not every form of cresol is harmful. The report now includes m-cresol, a substance that serves as a preservative.
Click to expand...
Can someone point me to that update? I haven't spotted Peter commenting in either of the STG chats.




m-Cresol - Hazardous Agents | Haz-Map



Haz-Map database entry with detailed information on the m-Cresol agent.

Image unavailable


www.haz-map.com
Click to expand...

Take another look at that COA

(link removed because the COA comes from a gb)

At 3-4mg/ml or below, m-cresol is acceptable.
Click to expand...
Found over on Meso, in the Analytical Lab Testing thread about Cresol — attachment included. As a preservative it's a bad pick, and that goes double for GLPs. Insulin isn't a GLP.

On top of that, Peter's remark never says whether the stuff is good or bad, only that it shows up. And the peak tells you nothing about quantity, since that assay doesn't report it. In his write-up on the test he notes it isn't included among the impurities either. Same story as his Jeep endo test, which simply read 2306EU. He left it to others to decide if that was bad, and most landed on the right answer.
Click to expand...
Reading your screenshot, it actually supports what I was saying — it mentions that M-cresol or phenol are used in multipens...

Regardless, it has no business being present, though calling it an automatic poison isn't accurate (it depends on how much is involved).
 
Habibibi said:

Chili777 said:

Habibibi said:

Chili777 said:

Habibibi said:

Not every form of cresol is harmful. The report now includes m-cresol, a substance that serves as a preservative.
Click to expand...
Can someone point me to that update? I haven't spotted Peter commenting in either of the STG chats.




m-Cresol - Hazardous Agents | Haz-Map



Haz-Map database entry with detailed information on the m-Cresol agent.

Image unavailable


www.haz-map.com
Click to expand...

Take another look at that COA

(link removed because the COA comes from a gb)

At 3-4mg/ml or below, m-cresol is acceptable.
Click to expand...
Found over on Meso, in the Analytical Lab Testing thread about Cresol — attachment included. As a preservative it's a bad pick, and that goes double for GLPs. Insulin isn't a GLP.

On top of that, Peter's remark never says whether the stuff is good or bad, only that it shows up. And the peak tells you nothing about quantity, since that assay doesn't report it. In his write-up on the test he notes it isn't included among the impurities either. Same story as his Jeep endo test, which simply read 2306EU. He left it to others to decide if that was bad, and most landed on the right answer.
Click to expand...
Reading your screenshot, it actually supports what I was saying — it mentions that M-cresol or phenol are used in multipens...

Regardless, it has no business being present, though calling it an automatic poison isn't accurate (it depends on how much is involved).
Click to expand...
For GLPs that get reconstituted, I came across a figure of 0.2% being permitted. Any amount of it showing up in lyophilized peptides is unjustifiable.
 
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