lessthanhalf said:
Losing weight by any route will shrink visceral and subcutaneous fat alike, along with lean muscle and organ mass. So when you drop pounds on reta, visceral fat goes down too. Because of its glucagon agonism, reta likely carries a small added benefit for visceral fat relative to other GLP drugs; it is clearly better than the other glp drugs at cutting liver fat, and liver fat and visceral fat usually move together. Still, the bulk of the effect comes from the weight loss itself. Tesa works differently: it does not produce weight loss, but it does appear to lower visceral fat more than subcutaneous fat, at least among people with HIV lipodystrophy, which is really the only group it has been tested on. On the whole, reta should have a far bigger impact on visceral fat than tesa, provided it drives a good amount of weight loss.