Another Teso ADHD Story

This thread is genuinely fascinating, and I'm happy I stumbled on it. At 28 I was diagnosed with ADHD, but before that came 8 years of a wrong bipolar diagnosis and a pile of psych meds that accomplished nothing beyond creating new problems and packing on pounds — at a time when my body had been healthy. Now, 4 years later, it's clear I'm definitely ADHD, and based on family anecdotes I've had it since toddlerhood. Once I finally got the correct diagnosis, my mom admitted to me that she has inattentive ADHD, yet she doesn't buy into diagnosing or medicating it. Thanks, Ma. That's 8 years of my life wasted while doctors hurled the kitchen sink at me.

Anyway, what strikes me as curious here is that teso appears to carry SNRI properties. Years back I gave welbutrin a shot, after sertraline left me unhappy due to sexual numbing. Welbutrin sent me off the rails — it looked like mania. I quit it after roughly 2 weeks, but that response kept the bogus bipolar label alive for a couple more years, since we kept citing it as 'that one time I definitely had a manic episode'. In reality it was nothing more than an uncommon reaction to welbutrin. Bipolar I am not, and never have been. What I actually had was bad depression plus severe, uncontrolled and unacknowledged ADHD symptoms, my whole life long.

So, after reading this I'm intrigued by teso, but wary of a repeat of the welbutrin-type reaction. The adderal xr I'm currently on doesn't thrill me, and I only take it 1x a week. The remaining 6 days I'm basically a slug of a human, which isn't ideal.
 
There are plenty of solid replies in this thread, along with plenty that miss the mark. My own experience with ADHD goes back to 1981. Every medication out there has been on my list at some point, and for me stimulants tend to work the best. The problem is that tolerance creeps up fast, which I don't care for. During several years spent in a lab setting doing medication studies, Teso came up constantly in ADHD conversations. What we saw was no genuine long-term benefit from IT. Any short-term effects were on the mild side, and a lot of people described feeling jittery. Even when tesofensine leaves someone feeling more awake, energetic, or motivated, working memory, distractibility, organization, sustained attention, and executive control can remain just as difficult. Anxiety, restlessness, insomnia, or a "wired" sensation that ends up hurting concentration rather than helping it can sometimes result from too much norepinephrine or serotonergic stimulation. This isn't me claiming it won't work for you; personally I like it because that wired feeling never hits me, though it does hit many others. Side: Note, Our strongest responders used a extended release caffeine with their Teso. Good luck.
 
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