1st shot 5/25

[BNLFL]

kmngq said:

Took my 2nd injection on Sunday. 1mg.

Honestly, I have no idea whether it's doing anything. I suppose not having any side effects is a positive thing.

That dose is on the low side. Either follow what @birdwhacker suggested, or keep it there for a full 4 weeks so it accumulates in your body, then raise it to 2mg.

birdwhacker said:

BNLFL said:

birdwhacker said:

Powerslide said:

Took my 3rd dose (1mg) on Saturday night (day 6) right before going to sleep, and it seemed to reduce the mild side effects I'd been having. That first night I slept well, but the following night I couldn't fall asleep and woke up a few hours later. It definitely appears to be accumulating in my system — even at 1mg I can't consume nearly as much as before. I'm thinking about junk food, soda, and similar stuff less and less, and for the most part I'm making better choices at the grocery store. This morning the scale showed 229. The khaki pants and black shorts I wear to work, which used to be stretched tight, no longer feel like they're cutting off my circulation, and trimming my toenails is a bit less uncomfortable.

Weeks 1 through 3 are the toughest stretch. Don't skip your supplements: a methylated B complex, trace minerals, magnesium taken at night, plus electrolytes — those are the floor, not the ceiling.

Since I'm clearly wired a little differently, here come the product links. In my view these are extremely helpful, maybe even mandatory, so that whatever side effects show up can be blamed on bad nutrition instead of the reta.

• https://a.co/d/09wqgsjj 1 pill after your evening meal; work up to 2 as your stool softness permits. Add fiber wherever you can — psillium husk (metamucil) works wonders.
  
• https://a.co/d/07E78CCj Honestly, buying most of these separately would be better. Still, not everyone is as into vitamins as I am, so here's a middle ground. Take it with food or without, however you tolerate it.
  
• https://a.co/d/08mqDPmk 2 every morning before eating.

That list is the floor. If side effects hit you and you haven't covered these basics, I've got no sympathy. NOW Foods liquid fish oil plus whatever psilium husk brand you like are also hugely helpful.

Now, back to those first 3 weeks...

Sleep problems will get worse before they get better. Eventually they settle down. Avoid carbs in the evening. Anything you eat past 5pm deserves caution, because it rides with you into sleep. Carbs make sleep worse. A little low fat cheese or casein protein powder before bed keeps you asleep and delivers solid lowfat, lowcarb protein. Casein breaks down slowly, so your body won't jolt you awake from insulin crashing (carbs gone) or cortisol (body acting like it's starving) surging overnight.

Your skin may get sensitive. If it's severe, an antihistamine can help, though it shouldn't reach that point. I also found my sense of smell permanently sharpened a touch.

During the first few weeks you might feel wiped out, stay in bed, and even like it — because for the first time in years you've stopped overeating. Don't settle in there. Time to show up and get 3+ balanced meals daily with enough protein. Time to learn TDEE, BMI, and cardio zones. Don't burn this chance.

Reta nudges your heartrate up slightly. Not a problem. If it ever turns noticeable or uncomfortable, that's probably an electrolyte imbalance — you need more sodium, potassium, or magnesium. Follow Daddy's instructions above and magnesium is covered.

Start doing cardio. It brings blood pressure down and keeps things moving as you get healthier.

At goal weight, that's when you can add testosterone and pleasure your wife 4 to 6 times a day.

Good luck on your journey!

P.S.

One more thing...

In my opinion, injecting reta weekly is idiotic. Reta's appetite suppression fades after 4-5 days. I inject every 3 days and I pity anyone going more than 5 days between injections. Anyone calling this bad information is wrong and should feel bad.

Starting weight, 236, current weight 207. 10 weeks. That's 3lbs a week, which is a little unhealthy. Began at 0.5mg, raised by 0.5mg every 2 days until reaching 2.33mg per week (1mg every 3 days). Bumped to 4.66mg/wk at week 5 (2mg every 3 days) and see no reason to increase dose further at this time. 27y/o male

It's not that I doubt you — this is simply how I do things. One injection weekly for us. As I see it, the hunger blunting stays steady. Over 19 weeks: 46lbs, which works out to 2.4lb each week on average.

BNLFL, that wasn't aimed at you! I was referring to folks who don't have your level of coolness. You're among the good ones!

Mind passing that message along to my wife, brother?

 

[birdwhacker]

BNLFL said:

kmngq said:

Took my 2nd injection on Sunday. 1mg.

Honestly, I have no idea whether it's doing anything. I suppose not having any side effects is a positive thing.

That dose is on the low side. Either follow what @birdwhacker suggested, or keep it there for a full 4 weeks so it accumulates in your body, then raise it to 2mg.

birdwhacker said:

BNLFL said:

birdwhacker said:

Powerslide said:

Took my 3rd dose (1mg) on Saturday night (day 6) right before going to sleep, and it seemed to reduce the mild side effects I'd been having. That first night I slept well, but the following night I couldn't fall asleep and woke up a few hours later. It definitely appears to be accumulating in my system — even at 1mg I can't consume nearly as much as before. I'm thinking about junk food, soda, and similar stuff less and less, and for the most part I'm making better choices at the grocery store. This morning the scale showed 229. The khaki pants and black shorts I wear to work, which used to be stretched tight, no longer feel like they're cutting off my circulation, and trimming my toenails is a bit less uncomfortable.

Weeks 1 through 3 are the toughest stretch. Don't skip your supplements: a methylated B complex, trace minerals, magnesium taken at night, plus electrolytes — those are the floor, not the ceiling.

Since I'm clearly wired a little differently, here come the product links. In my view these are extremely helpful, maybe even mandatory, so that whatever side effects show up can be blamed on bad nutrition instead of the reta.

• https://a.co/d/09wqgsjj 1 pill after your evening meal; work up to 2 as your stool softness permits. Add fiber wherever you can — psillium husk (metamucil) works wonders.
  
• https://a.co/d/07E78CCj Honestly, buying most of these separately would be better. Still, not everyone is as into vitamins as I am, so here's a middle ground. Take it with food or without, however you tolerate it.
  
• https://a.co/d/08mqDPmk 2 every morning before eating.

That list is the floor. If side effects hit you and you haven't covered these basics, I've got no sympathy. NOW Foods liquid fish oil plus whatever psilium husk brand you like are also hugely helpful.

Now, back to those first 3 weeks...

Sleep problems will get worse before they get better. Eventually they settle down. Avoid carbs in the evening. Anything you eat past 5pm deserves caution, because it rides with you into sleep. Carbs make sleep worse. A little low fat cheese or casein protein powder before bed keeps you asleep and delivers solid lowfat, lowcarb protein. Casein breaks down slowly, so your body won't jolt you awake from insulin crashing (carbs gone) or cortisol (body acting like it's starving) surging overnight.

Your skin may get sensitive. If it's severe, an antihistamine can help, though it shouldn't reach that point. I also found my sense of smell permanently sharpened a touch.

During the first few weeks you might feel wiped out, stay in bed, and even like it — because for the first time in years you've stopped overeating. Don't settle in there. Time to show up and get 3+ balanced meals daily with enough protein. Time to learn TDEE, BMI, and cardio zones. Don't burn this chance.

Reta nudges your heartrate up slightly. Not a problem. If it ever turns noticeable or uncomfortable, that's probably an electrolyte imbalance — you need more sodium, potassium, or magnesium. Follow Daddy's instructions above and magnesium is covered.

Start doing cardio. It brings blood pressure down and keeps things moving as you get healthier.

At goal weight, that's when you can add testosterone and pleasure your wife 4 to 6 times a day.

Good luck on your journey!

P.S.

One more thing...

In my opinion, injecting reta weekly is idiotic. Reta's appetite suppression fades after 4-5 days. I inject every 3 days and I pity anyone going more than 5 days between injections. Anyone calling this bad information is wrong and should feel bad.

Starting weight, 236, current weight 207. 10 weeks. That's 3lbs a week, which is a little unhealthy. Began at 0.5mg, raised by 0.5mg every 2 days until reaching 2.33mg per week (1mg every 3 days). Bumped to 4.66mg/wk at week 5 (2mg every 3 days) and see no reason to increase dose further at this time. 27y/o male

It's not that I doubt you — this is simply how I do things. One injection weekly for us. As I see it, the hunger blunting stays steady. Over 19 weeks: 46lbs, which works out to 2.4lb each week on average.

BNLFL, that wasn't aimed at you! I was referring to folks who don't have your level of coolness. You're among the good ones!

Mind passing that message along to my wife, brother?

Honestly, the only situations where I'd say 1mg makes sense are if someone is extremely sensitive, or if their diet and appetite are already dialed in.

In my own family, I saw 2 people begin at 1mg and then move to 2mg 4 weeks later. To me that looks like a clever method for burning time and ruining how well the drug will work down the road.

My mom was 1 of them. She ended up needing 6mg per week instead of 4mg, since 5mg wasn't sufficient for her. My take is that 1mg makes you tolerant to the drug quite fast. Acclimating takes only 1-2 weeks, and most side effects clear up within 3-4 weeks.

 

[BNLFL]

birdwhacker said:

BNLFL said:

kmngq said:

Took my 2nd injection on Sunday. 1mg.

Honestly, I have no idea whether it's doing anything. I suppose not having any side effects is a positive thing.

That dose is on the low side. Either follow what @birdwhacker suggested, or keep it there for a full 4 weeks so it accumulates in your body, then raise it to 2mg.

birdwhacker said:

BNLFL said:

birdwhacker said:

Powerslide said:

Took my 3rd dose (1mg) on Saturday night (day 6) right before going to sleep, and it seemed to reduce the mild side effects I'd been having. That first night I slept well, but the following night I couldn't fall asleep and woke up a few hours later. It definitely appears to be accumulating in my system — even at 1mg I can't consume nearly as much as before. I'm thinking about junk food, soda, and similar stuff less and less, and for the most part I'm making better choices at the grocery store. This morning the scale showed 229. The khaki pants and black shorts I wear to work, which used to be stretched tight, no longer feel like they're cutting off my circulation, and trimming my toenails is a bit less uncomfortable.

Weeks 1 through 3 are the toughest stretch. Don't skip your supplements: a methylated B complex, trace minerals, magnesium taken at night, plus electrolytes — those are the floor, not the ceiling.

Since I'm clearly wired a little differently, here come the product links. In my view these are extremely helpful, maybe even mandatory, so that whatever side effects show up can be blamed on bad nutrition instead of the reta.

• https://a.co/d/09wqgsjj 1 pill after your evening meal; work up to 2 as your stool softness permits. Add fiber wherever you can — psillium husk (metamucil) works wonders.
  
• https://a.co/d/07E78CCj Honestly, buying most of these separately would be better. Still, not everyone is as into vitamins as I am, so here's a middle ground. Take it with food or without, however you tolerate it.
  
• https://a.co/d/08mqDPmk 2 every morning before eating.

That list is the floor. If side effects hit you and you haven't covered these basics, I've got no sympathy. NOW Foods liquid fish oil plus whatever psilium husk brand you like are also hugely helpful.

Now, back to those first 3 weeks...

Sleep problems will get worse before they get better. Eventually they settle down. Avoid carbs in the evening. Anything you eat past 5pm deserves caution, because it rides with you into sleep. Carbs make sleep worse. A little low fat cheese or casein protein powder before bed keeps you asleep and delivers solid lowfat, lowcarb protein. Casein breaks down slowly, so your body won't jolt you awake from insulin crashing (carbs gone) or cortisol (body acting like it's starving) surging overnight.

Your skin may get sensitive. If it's severe, an antihistamine can help, though it shouldn't reach that point. I also found my sense of smell permanently sharpened a touch.

During the first few weeks you might feel wiped out, stay in bed, and even like it — because for the first time in years you've stopped overeating. Don't settle in there. Time to show up and get 3+ balanced meals daily with enough protein. Time to learn TDEE, BMI, and cardio zones. Don't burn this chance.

Reta nudges your heartrate up slightly. Not a problem. If it ever turns noticeable or uncomfortable, that's probably an electrolyte imbalance — you need more sodium, potassium, or magnesium. Follow Daddy's instructions above and magnesium is covered.

Start doing cardio. It brings blood pressure down and keeps things moving as you get healthier.

At goal weight, that's when you can add testosterone and pleasure your wife 4 to 6 times a day.

Good luck on your journey!

P.S.

One more thing...

In my opinion, injecting reta weekly is idiotic. Reta's appetite suppression fades after 4-5 days. I inject every 3 days and I pity anyone going more than 5 days between injections. Anyone calling this bad information is wrong and should feel bad.

Starting weight, 236, current weight 207. 10 weeks. That's 3lbs a week, which is a little unhealthy. Began at 0.5mg, raised by 0.5mg every 2 days until reaching 2.33mg per week (1mg every 3 days). Bumped to 4.66mg/wk at week 5 (2mg every 3 days) and see no reason to increase dose further at this time. 27y/o male

It's not that I doubt you — this is simply how I do things. One injection weekly for us. As I see it, the hunger blunting stays steady. Over 19 weeks: 46lbs, which works out to 2.4lb each week on average.

BNLFL, that wasn't aimed at you! I was referring to folks who don't have your level of coolness. You're among the good ones!

Mind passing that message along to my wife, brother?

Honestly, the only situations where I'd say 1mg makes sense are if someone is extremely sensitive, or if their diet and appetite are already dialed in.

In my own family, I saw 2 people begin at 1mg and then move to 2mg 4 weeks later. To me that looks like a clever method for burning time and ruining how well the drug will work down the road.

My mom was 1 of them. She ended up needing 6mg per week instead of 4mg, since 5mg wasn't sufficient for her. My take is that 1mg makes you tolerant to the drug quite fast. Acclimating takes only 1-2 weeks, and most side effects clear up within 3-4 weeks.

Just experience, I suppose. My own start was 2mg. The folks whose posts really get to me — and I've replied to them directly — are the ones on .25, .5 and .75. Where they dug up those starting doses, I have no clue. Clearly they skipped the Lilly trials.

 

[birdwhacker]

BNLFL said:

birdwhacker said:

BNLFL said:

kmngq said:

Took my 2nd injection on Sunday. 1mg.

Honestly, I have no idea whether it's doing anything. I suppose not having any side effects is a positive thing.

That dose is on the low side. Either follow what @birdwhacker suggested, or keep it there for a full 4 weeks so it accumulates in your body, then raise it to 2mg.

birdwhacker said:

BNLFL said:

birdwhacker said:

Powerslide said:

Took my 3rd dose (1mg) on Saturday night (day 6) right before going to sleep, and it seemed to reduce the mild side effects I'd been having. That first night I slept well, but the following night I couldn't fall asleep and woke up a few hours later. It definitely appears to be accumulating in my system — even at 1mg I can't consume nearly as much as before. I'm thinking about junk food, soda, and similar stuff less and less, and for the most part I'm making better choices at the grocery store. This morning the scale showed 229. The khaki pants and black shorts I wear to work, which used to be stretched tight, no longer feel like they're cutting off my circulation, and trimming my toenails is a bit less uncomfortable.

Weeks 1 through 3 are the toughest stretch. Don't skip your supplements: a methylated B complex, trace minerals, magnesium taken at night, plus electrolytes — those are the floor, not the ceiling.

Since I'm clearly wired a little differently, here come the product links. In my view these are extremely helpful, maybe even mandatory, so that whatever side effects show up can be blamed on bad nutrition instead of the reta.

• https://a.co/d/09wqgsjj 1 pill after your evening meal; work up to 2 as your stool softness permits. Add fiber wherever you can — psillium husk (metamucil) works wonders.
  
• https://a.co/d/07E78CCj Honestly, buying most of these separately would be better. Still, not everyone is as into vitamins as I am, so here's a middle ground. Take it with food or without, however you tolerate it.
  
• https://a.co/d/08mqDPmk 2 every morning before eating.

That list is the floor. If side effects hit you and you haven't covered these basics, I've got no sympathy. NOW Foods liquid fish oil plus whatever psilium husk brand you like are also hugely helpful.

Now, back to those first 3 weeks...

Sleep problems will get worse before they get better. Eventually they settle down. Avoid carbs in the evening. Anything you eat past 5pm deserves caution, because it rides with you into sleep. Carbs make sleep worse. A little low fat cheese or casein protein powder before bed keeps you asleep and delivers solid lowfat, lowcarb protein. Casein breaks down slowly, so your body won't jolt you awake from insulin crashing (carbs gone) or cortisol (body acting like it's starving) surging overnight.

Your skin may get sensitive. If it's severe, an antihistamine can help, though it shouldn't reach that point. I also found my sense of smell permanently sharpened a touch.

During the first few weeks you might feel wiped out, stay in bed, and even like it — because for the first time in years you've stopped overeating. Don't settle in there. Time to show up and get 3+ balanced meals daily with enough protein. Time to learn TDEE, BMI, and cardio zones. Don't burn this chance.

Reta nudges your heartrate up slightly. Not a problem. If it ever turns noticeable or uncomfortable, that's probably an electrolyte imbalance — you need more sodium, potassium, or magnesium. Follow Daddy's instructions above and magnesium is covered.

Start doing cardio. It brings blood pressure down and keeps things moving as you get healthier.

At goal weight, that's when you can add testosterone and pleasure your wife 4 to 6 times a day.

Good luck on your journey!

P.S.

One more thing...

In my opinion, injecting reta weekly is idiotic. Reta's appetite suppression fades after 4-5 days. I inject every 3 days and I pity anyone going more than 5 days between injections. Anyone calling this bad information is wrong and should feel bad.

Starting weight, 236, current weight 207. 10 weeks. That's 3lbs a week, which is a little unhealthy. Began at 0.5mg, raised by 0.5mg every 2 days until reaching 2.33mg per week (1mg every 3 days). Bumped to 4.66mg/wk at week 5 (2mg every 3 days) and see no reason to increase dose further at this time. 27y/o male

It's not that I doubt you — this is simply how I do things. One injection weekly for us. As I see it, the hunger blunting stays steady. Over 19 weeks: 46lbs, which works out to 2.4lb each week on average.

BNLFL, that wasn't aimed at you! I was referring to folks who don't have your level of coolness. You're among the good ones!

Mind passing that message along to my wife, brother?

Honestly, the only situations where I'd say 1mg makes sense are if someone is extremely sensitive, or if their diet and appetite are already dialed in.

In my own family, I saw 2 people begin at 1mg and then move to 2mg 4 weeks later. To me that looks like a clever method for burning time and ruining how well the drug will work down the road.

My mom was 1 of them. She ended up needing 6mg per week instead of 4mg, since 5mg wasn't sufficient for her. My take is that 1mg makes you tolerant to the drug quite fast. Acclimating takes only 1-2 weeks, and most side effects clear up within 3-4 weeks.

Just experience, I suppose. My own start was 2mg. The folks whose posts really get to me — and I've replied to them directly — are the ones on .25, .5 and .75. Where they dug up those starting doses, I have no clue. Clearly they skipped the Lilly trials.

Yep, folks picked up on "lowest effective dose" and interpreted it as microdosing.

What it actually means: move up fast until you hit a dose that does the job, then park there for as long as it keeps working.

 

[BlueDog55]

BNLFL said:

Powerslide said:

Day 6, and since the half life is 6 days, I'll wait out the 6 days then inject. This morning my wife administered the shot into my arm (10 units, or 1mg). I still wound up with some discomfort in the R lower back lasting a couple hours, so it seems the injection site wasn't the cause. My guess is that's where the kidney sits. Has anyone reported kidney discomfort? It wasn't unbearable and I kept up with my day, just something I picked up on. Over 5 hours have passed and a slight headache is beginning, which also happened with the first shot, along with a bit of fatigue. I got on the scale and I'm down 5 pounds so far, at 233.

Yesterday I could eat much more before feeling full quickly. Around 4 I had eggs and sausage, then around 10 a meatball sub. I may not have eaten in the morning, can't remember now, likely only a coffee.

5lbs gone in 6 days? That's dropping weight way too quickly.

For week 1, yeah, that's a big drop — but if he quit 2 MtDos daily, the weight would likely have come off anyway, no Reta needed. A bunch of my friends and I all stopped coke, and each of us dropped roughly 20lbs over a month.

 

[BNLFL]

BlueDog55 said:

BNLFL said:

Powerslide said:

Day 6, and since the half life is 6 days, I'll wait out the 6 days then inject. This morning my wife administered the shot into my arm (10 units, or 1mg). I still wound up with some discomfort in the R lower back lasting a couple hours, so it seems the injection site wasn't the cause. My guess is that's where the kidney sits. Has anyone reported kidney discomfort? It wasn't unbearable and I kept up with my day, just something I picked up on. Over 5 hours have passed and a slight headache is beginning, which also happened with the first shot, along with a bit of fatigue. I got on the scale and I'm down 5 pounds so far, at 233.

Yesterday I could eat much more before feeling full quickly. Around 4 I had eggs and sausage, then around 10 a meatball sub. I may not have eaten in the morning, can't remember now, likely only a coffee.

5lbs gone in 6 days? That's dropping weight way too quickly.

For week 1, yeah, that's a big drop — but if he quit 2 MtDos daily, the weight would likely have come off anyway, no Reta needed. A bunch of my friends and I all stopped coke, and each of us dropped roughly 20lbs over a month.

Most of the drop in those opening weeks tends to be water.

 

[BlueDog55]

birdwhacker said:

Powerslide said:

Took my 3rd dose (1mg) on Saturday night (day 6) right before going to sleep, and it seemed to reduce the mild side effects I'd been having. That first night I slept well, but the following night I couldn't fall asleep and woke up a few hours later. It definitely appears to be accumulating in my system — even at 1mg I can't consume nearly as much as before. I'm thinking about junk food, soda, and similar stuff less and less, and for the most part I'm making better choices at the grocery store. This morning the scale showed 229. The khaki pants and black shorts I wear to work, which used to be stretched tight, no longer feel like they're cutting off my circulation, and trimming my toenails is a bit less uncomfortable.

Weeks 1 through 3 are the toughest stretch. Don't skip your supplements: a methylated B complex, trace minerals, magnesium taken at night, plus electrolytes — those are the floor, not the ceiling.

Since I'm clearly wired a little differently, here come the product links. In my view these are extremely helpful, maybe even mandatory, so that whatever side effects show up can be blamed on bad nutrition instead of the reta.

• https://a.co/d/09wqgsjj 1 pill after your evening meal; work up to 2 as your stool softness permits. Add fiber wherever you can — psillium husk (metamucil) works wonders.
  
• https://a.co/d/07E78CCj Honestly, buying most of these separately would be better. Still, not everyone is as into vitamins as I am, so here's a middle ground. Take it with food or without, however you tolerate it.
  
• https://a.co/d/08mqDPmk 2 every morning before eating.

That list is the floor. If side effects hit you and you haven't covered these basics, I've got no sympathy. NOW Foods liquid fish oil plus whatever psilium husk brand you like are also hugely helpful.

Now, back to those first 3 weeks...

Sleep problems will get worse before they get better. Eventually they settle down. Avoid carbs in the evening. Anything you eat past 5pm deserves caution, because it rides with you into sleep. Carbs make sleep worse. A little low fat cheese or casein protein powder before bed keeps you asleep and delivers solid lowfat, lowcarb protein. Casein breaks down slowly, so your body won't jolt you awake from insulin crashing (carbs gone) or cortisol (body acting like it's starving) surging overnight.

Your skin may get sensitive. If it's severe, an antihistamine can help, though it shouldn't reach that point. I also found my sense of smell permanently sharpened a touch.

During the first few weeks you might feel wiped out, stay in bed, and even like it — because for the first time in years you've stopped overeating. Don't settle in there. Time to show up and get 3+ balanced meals daily with enough protein. Time to learn TDEE, BMI, and cardio zones. Don't burn this chance.

Reta nudges your heartrate up slightly. Not a problem. If it ever turns noticeable or uncomfortable, that's probably an electrolyte imbalance — you need more sodium, potassium, or magnesium. Follow Daddy's instructions above and magnesium is covered.

Start doing cardio. It brings blood pressure down and keeps things moving as you get healthier.

At goal weight, that's when you can add testosterone and pleasure your wife 4 to 6 times a day.

Good luck on your journey!

P.S.

One more thing...

In my opinion, injecting reta weekly is idiotic. Reta's appetite suppression fades after 4-5 days. I inject every 3 days and I pity anyone going more than 5 days between injections. Anyone calling this bad information is wrong and should feel bad.

Starting weight, 236, current weight 207. 10 weeks. That's 3lbs a week, which is a little unhealthy. Began at 0.5mg, raised by 0.5mg every 2 days until reaching 2.33mg per week (1mg every 3 days). Bumped to 4.66mg/wk at week 5 (2mg every 3 days) and see no reason to increase dose further at this time. 27y/o male

Each person reacts differently. My routine: 1 injection per 7 days. Over 8 weeks at 1mg weekly, I dropped 30lbs. Then I paused for a month, restarted, and 2 weeks in I've shed 6lbs. Important context: prior to starting, I'd eaten carnivore-style for 4 months and already lost 20-25lbs, so my diet was already solid when I began Reta. I haven't felt it fade at day 4-5. Also, I've never gone above 1mg. Guess I'm a strong responder. BTW, not claiming your info is wrong—just that everyone is different. Your info is helpful and I don't dispute it, except it comes across as the only approach.

 

[birdwhacker]

BlueDog55 said:

birdwhacker said:

Powerslide said:

Took my 3rd dose (1mg) on Saturday night (day 6) right before going to sleep, and it seemed to reduce the mild side effects I'd been having. That first night I slept well, but the following night I couldn't fall asleep and woke up a few hours later. It definitely appears to be accumulating in my system — even at 1mg I can't consume nearly as much as before. I'm thinking about junk food, soda, and similar stuff less and less, and for the most part I'm making better choices at the grocery store. This morning the scale showed 229. The khaki pants and black shorts I wear to work, which used to be stretched tight, no longer feel like they're cutting off my circulation, and trimming my toenails is a bit less uncomfortable.

Weeks 1 through 3 are the toughest stretch. Don't skip your supplements: a methylated B complex, trace minerals, magnesium taken at night, plus electrolytes — those are the floor, not the ceiling.

Since I'm clearly wired a little differently, here come the product links. In my view these are extremely helpful, maybe even mandatory, so that whatever side effects show up can be blamed on bad nutrition instead of the reta.

• https://a.co/d/09wqgsjj 1 pill after your evening meal; work up to 2 as your stool softness permits. Add fiber wherever you can — psillium husk (metamucil) works wonders.
  
• https://a.co/d/07E78CCj Honestly, buying most of these separately would be better. Still, not everyone is as into vitamins as I am, so here's a middle ground. Take it with food or without, however you tolerate it.
  
• https://a.co/d/08mqDPmk 2 every morning before eating.

That list is the floor. If side effects hit you and you haven't covered these basics, I've got no sympathy. NOW Foods liquid fish oil plus whatever psilium husk brand you like are also hugely helpful.

Now, back to those first 3 weeks...

Sleep problems will get worse before they get better. Eventually they settle down. Avoid carbs in the evening. Anything you eat past 5pm deserves caution, because it rides with you into sleep. Carbs make sleep worse. A little low fat cheese or casein protein powder before bed keeps you asleep and delivers solid lowfat, lowcarb protein. Casein breaks down slowly, so your body won't jolt you awake from insulin crashing (carbs gone) or cortisol (body acting like it's starving) surging overnight.

Your skin may get sensitive. If it's severe, an antihistamine can help, though it shouldn't reach that point. I also found my sense of smell permanently sharpened a touch.

During the first few weeks you might feel wiped out, stay in bed, and even like it — because for the first time in years you've stopped overeating. Don't settle in there. Time to show up and get 3+ balanced meals daily with enough protein. Time to learn TDEE, BMI, and cardio zones. Don't burn this chance.

Reta nudges your heartrate up slightly. Not a problem. If it ever turns noticeable or uncomfortable, that's probably an electrolyte imbalance — you need more sodium, potassium, or magnesium. Follow Daddy's instructions above and magnesium is covered.

Start doing cardio. It brings blood pressure down and keeps things moving as you get healthier.

At goal weight, that's when you can add testosterone and pleasure your wife 4 to 6 times a day.

Good luck on your journey!

P.S.

One more thing...

In my opinion, injecting reta weekly is idiotic. Reta's appetite suppression fades after 4-5 days. I inject every 3 days and I pity anyone going more than 5 days between injections. Anyone calling this bad information is wrong and should feel bad.

Starting weight, 236, current weight 207. 10 weeks. That's 3lbs a week, which is a little unhealthy. Began at 0.5mg, raised by 0.5mg every 2 days until reaching 2.33mg per week (1mg every 3 days). Bumped to 4.66mg/wk at week 5 (2mg every 3 days) and see no reason to increase dose further at this time. 27y/o male

Each person reacts differently. My routine: 1 injection per 7 days. Over 8 weeks at 1mg weekly, I dropped 30lbs. Then I paused for a month, restarted, and 2 weeks in I've shed 6lbs. Important context: prior to starting, I'd eaten carnivore-style for 4 months and already lost 20-25lbs, so my diet was already solid when I began Reta. I haven't felt it fade at day 4-5. Also, I've never gone above 1mg. Guess I'm a strong responder. BTW, not claiming your info is wrong—just that everyone is different. Your info is helpful and I don't dispute it, except it comes across as the only approach.

Look, you're the outlier here. That's fantastic progress. I wasn't referring to you — I meant the riff raff!

That said... my hunch is that splitting your dose would have produced identical results! The reverse, however, wouldn't hold true

 

[Powerslide]

Shot number 4. The research partner who handles my injections nodded off early on Friday evening, which meant I ended up a day behind schedule. She administered 1mg last night (7 days). Sleep was rough, though we had a race last night and on those evenings my mind tends to stay wired. No side effects to report today, and appetite suppression seems to be working again — I haven't wanted to eat anything this morning. My weight has been fluctuating all week, landing anywhere between 226 and 232. I'm weighing whether to take another 1mg in 3 days, or simply wait out the 6 days and then bump up to 2mg. This week's food choices likely weren't the healthiest; with races and activities nearly every evening, fast food made up a lot of it.

 

[Powerslide]

Haven't posted an update for about 2 weeks. Following my previous update, I switched to 1mg every 3-4 days, and since then my weight loss has mostly stalled — possibly I've even put a couple pounds back on. I added the mag, b12 and micro/macro that bird recommended earlier in the thread. Last week I was worn out nearly every day; when evening came I had no motivation to head into the garage and work on my projects, and some afternoons I napped (sometime between 5-7pm). I'm aware others have reported feeling tired/sluggish on this stuff, but I'm only at about 2mg per week. Eating early in the day is difficult for me — usually just a coffee, and many days I still have no appetite by lunch. I suspect that might be contributing to my evening fatigue. Yesterday I made myself eat a bit of eggs and sausage, and afterward I had stomach cramps for most of the day. My bowels have also slowed somewhat, though I figure that's to be expected when you're consuming less. The weather this week was pretty lousy, which could be a factor — rainy/dreary weather has a real impact on the wife's mood, though I've never noticed it affecting me. Tonight I'm moving up to a 2mg shot.

 

[Powerslide]

Sitting at roughly 210 now.

Switched to 2mg on 6/29, and I've kept to that schedule every 6 days since.

I'm still drawing from the original vial, which makes it about 80 days old by now. From what I gather, the majority of folks aim to finish theirs inside 60 days. The only size I could get was a 30mg, so that's the one I reconstituted. Lately it feels like the headache side effects are ramping up rather than easing off during the first couple days following the pin. I'm trying to figure out whether this is a hydration thing or possibly tied to how long the vial has been sitting.

If anyone has run reta beyond the 60 day mark after reconstituting, I'd like to hear whether their sides got worse as the vial got older.

 

[Skidude]

Powerslide said:

Sitting at roughly 210 now.

Switched to 2mg on 6/29, and I've kept to that schedule every 6 days since.

I'm still drawing from the original vial, which makes it about 80 days old by now. From what I gather, the majority of folks aim to finish theirs inside 60 days. The only size I could get was a 30mg, so that's the one I reconstituted. Lately it feels like the headache side effects are ramping up rather than easing off during the first couple days following the pin. I'm trying to figure out whether this is a hydration thing or possibly tied to how long the vial has been sitting.

If anyone has run reta beyond the 60 day mark after reconstituting, I'd like to hear whether their sides got worse as the vial got older.

Reason suggests 3 possible explanations, though none is guaranteed

1. Degradation- this wouldn't lead to stronger side effects, possibly milder ones since potency drops
   
2. hydration- this can bring on headaches
   
3. Bacteria/endo buildup- this might turn it cloudy, show floaters, or cause ISR

Injecting endotoxins (lipopolysaccharides from gram-negative bacteria) subcutaneously typically causes localized inflammation and systemic flu-like reactions. [1, 2, 3]

Local Symptoms at Injection Site

• • Redness (Erythema): The skin around the injection site becomes pink or red.
  • Swelling (Edema): Fluid builds up, creating a firm or puffy lump.
  • Pain and Tenderness: The area hurts when touched or moved.
  • Warmth: The skin feels hot to the touch.
  • Local Necrosis: In severe or hypersensitive reactions, tissue damage or localized tissue death can occur. [1, 2, 3, 4, 5]

Systemic (Whole Body) Symptoms

• • Fever and Chills: A sudden spike in body temperature accompanied by severe shaking chills (rigors).
  • Headache and Aches: Generalized muscle aches (myalgia), joint pain (arthralgia), and severe headaches.
  • Nausea and Fatigue: Feelings of severe tiredness, malaise, upset stomach, or vomiting.
  • Low Blood Pressure: In high doses or severe systemic reactions, blood pressure can drop dangerously low, potentially leading to shock

Click to expand...

 

[Powerslide]

Skidude said:

Powerslide said:

Sitting at roughly 210 now.

Switched to 2mg on 6/29, and I've kept to that schedule every 6 days since.

I'm still drawing from the original vial, which makes it about 80 days old by now. From what I gather, the majority of folks aim to finish theirs inside 60 days. The only size I could get was a 30mg, so that's the one I reconstituted. Lately it feels like the headache side effects are ramping up rather than easing off during the first couple days following the pin. I'm trying to figure out whether this is a hydration thing or possibly tied to how long the vial has been sitting.

If anyone has run reta beyond the 60 day mark after reconstituting, I'd like to hear whether their sides got worse as the vial got older.

Reason suggests 3 possible explanations, though none is guaranteed

1. Degradation- this wouldn't lead to stronger side effects, possibly milder ones since potency drops
   
2. hydration- this can bring on headaches
   
3. Bacteria/endo buildup- this might turn it cloudy, show floaters, or cause ISR

Injecting endotoxins (lipopolysaccharides from gram-negative bacteria) subcutaneously typically causes localized inflammation and systemic flu-like reactions. [1, 2, 3]

Local Symptoms at Injection Site

• • Redness (Erythema): The skin around the injection site becomes pink or red.
  • Swelling (Edema): Fluid builds up, creating a firm or puffy lump.
  • Pain and Tenderness: The area hurts when touched or moved.
  • Warmth: The skin feels hot to the touch.
  • Local Necrosis: In severe or hypersensitive reactions, tissue damage or localized tissue death can occur. [1, 2, 3, 4, 5]

Systemic (Whole Body) Symptoms

• • Fever and Chills: A sudden spike in body temperature accompanied by severe shaking chills (rigors).
  • Headache and Aches: Generalized muscle aches (myalgia), joint pain (arthralgia), and severe headaches.
  • Nausea and Fatigue: Feelings of severe tiredness, malaise, upset stomach, or vomiting.
  • Low Blood Pressure: In high doses or severe systemic reactions, blood pressure can drop dangerously low, potentially leading to shock

Click to expand...

This morning, before injecting again, I inspected it. It remains clear. Today I took just 1.8mg, which is 18units, and on Thursday I'm heading out for a vacation.

 

[lessthanhalf]

Headaches show up a lot, and reta doesn't have to be the reason—though it could be. They might also come from the drop in weight, from eating less or eating differently, or from drinking fewer fluids. Or they might have nothing to do with any of that. Would you describe them as migraine-style (throbbing and on 1 side), or more like a vague, general tightness in the head? Have you dealt with headaches before? If this is something new for you, and it keeps happening, getting a medical opinion isn't a bad idea.

To me, contaminants or endotoxins seem like the least probable explanation.

When I added reta on top of tirz 15mg, I had the worst migraine cycle of my life. They hit every day at 5 or 6 am while I was asleep, eletriptan worked really well, but they returned daily for roughly 8 days. Eventually it stopped, thankfully. So I don't believe headache is a frequent side effect, but it clearly can happen. If they stick around and you get checked out, the worst case might just be having to switch to tirz.

 

[GLPFrodo]

birdwhacker said:

BNLFL said:

kmngq said:

Took my 2nd injection on Sunday. 1mg.

Honestly, I have no idea whether it's doing anything. I suppose not having any side effects is a positive thing.

That dose is on the low side. Either follow what @birdwhacker suggested, or keep it there for a full 4 weeks so it accumulates in your body, then raise it to 2mg.

birdwhacker said:

BNLFL said:

birdwhacker said:

Powerslide said:

Took my 3rd dose (1mg) on Saturday night (day 6) right before going to sleep, and it seemed to reduce the mild side effects I'd been having. That first night I slept well, but the following night I couldn't fall asleep and woke up a few hours later. It definitely appears to be accumulating in my system — even at 1mg I can't consume nearly as much as before. I'm thinking about junk food, soda, and similar stuff less and less, and for the most part I'm making better choices at the grocery store. This morning the scale showed 229. The khaki pants and black shorts I wear to work, which used to be stretched tight, no longer feel like they're cutting off my circulation, and trimming my toenails is a bit less uncomfortable.

Weeks 1 through 3 are the toughest stretch. Don't skip your supplements: a methylated B complex, trace minerals, magnesium taken at night, plus electrolytes — those are the floor, not the ceiling.

Since I'm clearly wired a little differently, here come the product links. In my view these are extremely helpful, maybe even mandatory, so that whatever side effects show up can be blamed on bad nutrition instead of the reta.

• https://a.co/d/09wqgsjj 1 pill after your evening meal; work up to 2 as your stool softness permits. Add fiber wherever you can — psillium husk (metamucil) works wonders.
  
• https://a.co/d/07E78CCj Honestly, buying most of these separately would be better. Still, not everyone is as into vitamins as I am, so here's a middle ground. Take it with food or without, however you tolerate it.
  
• https://a.co/d/08mqDPmk 2 every morning before eating.

That list is the floor. If side effects hit you and you haven't covered these basics, I've got no sympathy. NOW Foods liquid fish oil plus whatever psilium husk brand you like are also hugely helpful.

Now, back to those first 3 weeks...

Sleep problems will get worse before they get better. Eventually they settle down. Avoid carbs in the evening. Anything you eat past 5pm deserves caution, because it rides with you into sleep. Carbs make sleep worse. A little low fat cheese or casein protein powder before bed keeps you asleep and delivers solid lowfat, lowcarb protein. Casein breaks down slowly, so your body won't jolt you awake from insulin crashing (carbs gone) or cortisol (body acting like it's starving) surging overnight.

Your skin may get sensitive. If it's severe, an antihistamine can help, though it shouldn't reach that point. I also found my sense of smell permanently sharpened a touch.

During the first few weeks you might feel wiped out, stay in bed, and even like it — because for the first time in years you've stopped overeating. Don't settle in there. Time to show up and get 3+ balanced meals daily with enough protein. Time to learn TDEE, BMI, and cardio zones. Don't burn this chance.

Reta nudges your heartrate up slightly. Not a problem. If it ever turns noticeable or uncomfortable, that's probably an electrolyte imbalance — you need more sodium, potassium, or magnesium. Follow Daddy's instructions above and magnesium is covered.

Start doing cardio. It brings blood pressure down and keeps things moving as you get healthier.

At goal weight, that's when you can add testosterone and pleasure your wife 4 to 6 times a day.

Good luck on your journey!

P.S.

One more thing...

In my opinion, injecting reta weekly is idiotic. Reta's appetite suppression fades after 4-5 days. I inject every 3 days and I pity anyone going more than 5 days between injections. Anyone calling this bad information is wrong and should feel bad.

Starting weight, 236, current weight 207. 10 weeks. That's 3lbs a week, which is a little unhealthy. Began at 0.5mg, raised by 0.5mg every 2 days until reaching 2.33mg per week (1mg every 3 days). Bumped to 4.66mg/wk at week 5 (2mg every 3 days) and see no reason to increase dose further at this time. 27y/o male

It's not that I doubt you — this is simply how I do things. One injection weekly for us. As I see it, the hunger blunting stays steady. Over 19 weeks: 46lbs, which works out to 2.4lb each week on average.

BNLFL, that wasn't aimed at you! I was referring to folks who don't have your level of coolness. You're among the good ones!

Mind passing that message along to my wife, brother?

Honestly, the only situations where I'd say 1mg makes sense are if someone is extremely sensitive, or if their diet and appetite are already dialed in.

In my own family, I saw 2 people begin at 1mg and then move to 2mg 4 weeks later. To me that looks like a clever method for burning time and ruining how well the drug will work down the road.

My mom was 1 of them. She ended up needing 6mg per week instead of 4mg, since 5mg wasn't sufficient for her. My take is that 1mg makes you tolerant to the drug quite fast. Acclimating takes only 1-2 weeks, and most side effects clear up within 3-4 weeks.

From some study material I went through, beginning at a lower dose seems to aid adaptation — or plasticity, to use their term — and greatly lessens side effects while a person titrates upward. When the starting dose was higher, the findings indicated the body never adjusted, and those in that group continued to have noticeably more side effects.

 

[BNLFL]

For the most part, my adverse reactions have cleared up, though the problem with sleep remains. I'm waiting on a response from my cardiologist regarding 2 options I'd like to test for sleep.

 

[birdwhacker]

GLPFrodo said:

birdwhacker said:

BNLFL said:

kmngq said:

Took my 2nd injection on Sunday. 1mg.

Honestly, I have no idea whether it's doing anything. I suppose not having any side effects is a positive thing.

That dose is on the low side. Either follow what @birdwhacker suggested, or keep it there for a full 4 weeks so it accumulates in your body, then raise it to 2mg.

birdwhacker said:

BNLFL said:

birdwhacker said:

Powerslide said:

Took my 3rd dose (1mg) on Saturday night (day 6) right before going to sleep, and it seemed to reduce the mild side effects I'd been having. That first night I slept well, but the following night I couldn't fall asleep and woke up a few hours later. It definitely appears to be accumulating in my system — even at 1mg I can't consume nearly as much as before. I'm thinking about junk food, soda, and similar stuff less and less, and for the most part I'm making better choices at the grocery store. This morning the scale showed 229. The khaki pants and black shorts I wear to work, which used to be stretched tight, no longer feel like they're cutting off my circulation, and trimming my toenails is a bit less uncomfortable.

Weeks 1 through 3 are the toughest stretch. Don't skip your supplements: a methylated B complex, trace minerals, magnesium taken at night, plus electrolytes — those are the floor, not the ceiling.

Since I'm clearly wired a little differently, here come the product links. In my view these are extremely helpful, maybe even mandatory, so that whatever side effects show up can be blamed on bad nutrition instead of the reta.

• https://a.co/d/09wqgsjj 1 pill after your evening meal; work up to 2 as your stool softness permits. Add fiber wherever you can — psillium husk (metamucil) works wonders.
  
• https://a.co/d/07E78CCj Honestly, buying most of these separately would be better. Still, not everyone is as into vitamins as I am, so here's a middle ground. Take it with food or without, however you tolerate it.
  
• https://a.co/d/08mqDPmk 2 every morning before eating.

That list is the floor. If side effects hit you and you haven't covered these basics, I've got no sympathy. NOW Foods liquid fish oil plus whatever psilium husk brand you like are also hugely helpful.

Now, back to those first 3 weeks...

Sleep problems will get worse before they get better. Eventually they settle down. Avoid carbs in the evening. Anything you eat past 5pm deserves caution, because it rides with you into sleep. Carbs make sleep worse. A little low fat cheese or casein protein powder before bed keeps you asleep and delivers solid lowfat, lowcarb protein. Casein breaks down slowly, so your body won't jolt you awake from insulin crashing (carbs gone) or cortisol (body acting like it's starving) surging overnight.

Your skin may get sensitive. If it's severe, an antihistamine can help, though it shouldn't reach that point. I also found my sense of smell permanently sharpened a touch.

During the first few weeks you might feel wiped out, stay in bed, and even like it — because for the first time in years you've stopped overeating. Don't settle in there. Time to show up and get 3+ balanced meals daily with enough protein. Time to learn TDEE, BMI, and cardio zones. Don't burn this chance.

Reta nudges your heartrate up slightly. Not a problem. If it ever turns noticeable or uncomfortable, that's probably an electrolyte imbalance — you need more sodium, potassium, or magnesium. Follow Daddy's instructions above and magnesium is covered.

Start doing cardio. It brings blood pressure down and keeps things moving as you get healthier.

At goal weight, that's when you can add testosterone and pleasure your wife 4 to 6 times a day.

Good luck on your journey!

P.S.

One more thing...

In my opinion, injecting reta weekly is idiotic. Reta's appetite suppression fades after 4-5 days. I inject every 3 days and I pity anyone going more than 5 days between injections. Anyone calling this bad information is wrong and should feel bad.

Starting weight, 236, current weight 207. 10 weeks. That's 3lbs a week, which is a little unhealthy. Began at 0.5mg, raised by 0.5mg every 2 days until reaching 2.33mg per week (1mg every 3 days). Bumped to 4.66mg/wk at week 5 (2mg every 3 days) and see no reason to increase dose further at this time. 27y/o male

It's not that I doubt you — this is simply how I do things. One injection weekly for us. As I see it, the hunger blunting stays steady. Over 19 weeks: 46lbs, which works out to 2.4lb each week on average.

BNLFL, that wasn't aimed at you! I was referring to folks who don't have your level of coolness. You're among the good ones!

Mind passing that message along to my wife, brother?

Honestly, the only situations where I'd say 1mg makes sense are if someone is extremely sensitive, or if their diet and appetite are already dialed in.

In my own family, I saw 2 people begin at 1mg and then move to 2mg 4 weeks later. To me that looks like a clever method for burning time and ruining how well the drug will work down the road.

My mom was 1 of them. She ended up needing 6mg per week instead of 4mg, since 5mg wasn't sufficient for her. My take is that 1mg makes you tolerant to the drug quite fast. Acclimating takes only 1-2 weeks, and most side effects clear up within 3-4 weeks.

From some study material I went through, beginning at a lower dose seems to aid adaptation — or plasticity, to use their term — and greatly lessens side effects while a person titrates upward. When the starting dose was higher, the findings indicated the body never adjusted, and those in that group continued to have noticeably more side effects.

That's just some anonymous individual's claim, not research. Going in too high or ramping up too fast is clearly a bad idea, but the goal should be to begin at or close to a dose that actually works. Begin too low and your responsiveness to the medication fades, meaning you'll need more of it to get results other people reach on a smaller amount.

 

[BNLFL]

GLPFrodo said:

birdwhacker said:

BNLFL said:

kmngq said:

Took my 2nd injection on Sunday. 1mg.

Honestly, I have no idea whether it's doing anything. I suppose not having any side effects is a positive thing.

That dose is on the low side. Either follow what @birdwhacker suggested, or keep it there for a full 4 weeks so it accumulates in your body, then raise it to 2mg.

birdwhacker said:

BNLFL said:

birdwhacker said:

Powerslide said:

Took my 3rd dose (1mg) on Saturday night (day 6) right before going to sleep, and it seemed to reduce the mild side effects I'd been having. That first night I slept well, but the following night I couldn't fall asleep and woke up a few hours later. It definitely appears to be accumulating in my system — even at 1mg I can't consume nearly as much as before. I'm thinking about junk food, soda, and similar stuff less and less, and for the most part I'm making better choices at the grocery store. This morning the scale showed 229. The khaki pants and black shorts I wear to work, which used to be stretched tight, no longer feel like they're cutting off my circulation, and trimming my toenails is a bit less uncomfortable.

Weeks 1 through 3 are the toughest stretch. Don't skip your supplements: a methylated B complex, trace minerals, magnesium taken at night, plus electrolytes — those are the floor, not the ceiling.

Since I'm clearly wired a little differently, here come the product links. In my view these are extremely helpful, maybe even mandatory, so that whatever side effects show up can be blamed on bad nutrition instead of the reta.

• https://a.co/d/09wqgsjj 1 pill after your evening meal; work up to 2 as your stool softness permits. Add fiber wherever you can — psillium husk (metamucil) works wonders.
  
• https://a.co/d/07E78CCj Honestly, buying most of these separately would be better. Still, not everyone is as into vitamins as I am, so here's a middle ground. Take it with food or without, however you tolerate it.
  
• https://a.co/d/08mqDPmk 2 every morning before eating.

That list is the floor. If side effects hit you and you haven't covered these basics, I've got no sympathy. NOW Foods liquid fish oil plus whatever psilium husk brand you like are also hugely helpful.

Now, back to those first 3 weeks...

Sleep problems will get worse before they get better. Eventually they settle down. Avoid carbs in the evening. Anything you eat past 5pm deserves caution, because it rides with you into sleep. Carbs make sleep worse. A little low fat cheese or casein protein powder before bed keeps you asleep and delivers solid lowfat, lowcarb protein. Casein breaks down slowly, so your body won't jolt you awake from insulin crashing (carbs gone) or cortisol (body acting like it's starving) surging overnight.

Your skin may get sensitive. If it's severe, an antihistamine can help, though it shouldn't reach that point. I also found my sense of smell permanently sharpened a touch.

During the first few weeks you might feel wiped out, stay in bed, and even like it — because for the first time in years you've stopped overeating. Don't settle in there. Time to show up and get 3+ balanced meals daily with enough protein. Time to learn TDEE, BMI, and cardio zones. Don't burn this chance.

Reta nudges your heartrate up slightly. Not a problem. If it ever turns noticeable or uncomfortable, that's probably an electrolyte imbalance — you need more sodium, potassium, or magnesium. Follow Daddy's instructions above and magnesium is covered.

Start doing cardio. It brings blood pressure down and keeps things moving as you get healthier.

At goal weight, that's when you can add testosterone and pleasure your wife 4 to 6 times a day.

Good luck on your journey!

P.S.

One more thing...

In my opinion, injecting reta weekly is idiotic. Reta's appetite suppression fades after 4-5 days. I inject every 3 days and I pity anyone going more than 5 days between injections. Anyone calling this bad information is wrong and should feel bad.

Starting weight, 236, current weight 207. 10 weeks. That's 3lbs a week, which is a little unhealthy. Began at 0.5mg, raised by 0.5mg every 2 days until reaching 2.33mg per week (1mg every 3 days). Bumped to 4.66mg/wk at week 5 (2mg every 3 days) and see no reason to increase dose further at this time. 27y/o male

It's not that I doubt you — this is simply how I do things. One injection weekly for us. As I see it, the hunger blunting stays steady. Over 19 weeks: 46lbs, which works out to 2.4lb each week on average.

BNLFL, that wasn't aimed at you! I was referring to folks who don't have your level of coolness. You're among the good ones!

Mind passing that message along to my wife, brother?

Honestly, the only situations where I'd say 1mg makes sense are if someone is extremely sensitive, or if their diet and appetite are already dialed in.

In my own family, I saw 2 people begin at 1mg and then move to 2mg 4 weeks later. To me that looks like a clever method for burning time and ruining how well the drug will work down the road.

My mom was 1 of them. She ended up needing 6mg per week instead of 4mg, since 5mg wasn't sufficient for her. My take is that 1mg makes you tolerant to the drug quite fast. Acclimating takes only 1-2 weeks, and most side effects clear up within 3-4 weeks.

From some study material I went through, beginning at a lower dose seems to aid adaptation — or plasticity, to use their term — and greatly lessens side effects while a person titrates upward. When the starting dose was higher, the findings indicated the body never adjusted, and those in that group continued to have noticeably more side effects.

My first week of January was when I began, at 2mg. Side effects were slight for me: a bit of nighttime heartburn, and possibly some bloating. Both of those faded a while ago, but the sleep issue that appeared late in the 6mg doses is still with me. Currently I'm on 9mg. Apart from sleep, I have nothing else going on, which rather undermines that theory. Still, no two people are alike.

 

[GLPFrodo]

birdwhacker said:

GLPFrodo said:

birdwhacker said:

BNLFL said:

kmngq said:

Took my 2nd injection on Sunday. 1mg.

Honestly, I have no idea whether it's doing anything. I suppose not having any side effects is a positive thing.

That dose is on the low side. Either follow what @birdwhacker suggested, or keep it there for a full 4 weeks so it accumulates in your body, then raise it to 2mg.

birdwhacker said:

BNLFL said:

birdwhacker said:

Powerslide said:

Took my 3rd dose (1mg) on Saturday night (day 6) right before going to sleep, and it seemed to reduce the mild side effects I'd been having. That first night I slept well, but the following night I couldn't fall asleep and woke up a few hours later. It definitely appears to be accumulating in my system — even at 1mg I can't consume nearly as much as before. I'm thinking about junk food, soda, and similar stuff less and less, and for the most part I'm making better choices at the grocery store. This morning the scale showed 229. The khaki pants and black shorts I wear to work, which used to be stretched tight, no longer feel like they're cutting off my circulation, and trimming my toenails is a bit less uncomfortable.

Weeks 1 through 3 are the toughest stretch. Don't skip your supplements: a methylated B complex, trace minerals, magnesium taken at night, plus electrolytes — those are the floor, not the ceiling.

Since I'm clearly wired a little differently, here come the product links. In my view these are extremely helpful, maybe even mandatory, so that whatever side effects show up can be blamed on bad nutrition instead of the reta.

• https://a.co/d/09wqgsjj 1 pill after your evening meal; work up to 2 as your stool softness permits. Add fiber wherever you can — psillium husk (metamucil) works wonders.
  
• https://a.co/d/07E78CCj Honestly, buying most of these separately would be better. Still, not everyone is as into vitamins as I am, so here's a middle ground. Take it with food or without, however you tolerate it.
  
• https://a.co/d/08mqDPmk 2 every morning before eating.

That list is the floor. If side effects hit you and you haven't covered these basics, I've got no sympathy. NOW Foods liquid fish oil plus whatever psilium husk brand you like are also hugely helpful.

Now, back to those first 3 weeks...

Sleep problems will get worse before they get better. Eventually they settle down. Avoid carbs in the evening. Anything you eat past 5pm deserves caution, because it rides with you into sleep. Carbs make sleep worse. A little low fat cheese or casein protein powder before bed keeps you asleep and delivers solid lowfat, lowcarb protein. Casein breaks down slowly, so your body won't jolt you awake from insulin crashing (carbs gone) or cortisol (body acting like it's starving) surging overnight.

Your skin may get sensitive. If it's severe, an antihistamine can help, though it shouldn't reach that point. I also found my sense of smell permanently sharpened a touch.

During the first few weeks you might feel wiped out, stay in bed, and even like it — because for the first time in years you've stopped overeating. Don't settle in there. Time to show up and get 3+ balanced meals daily with enough protein. Time to learn TDEE, BMI, and cardio zones. Don't burn this chance.

Reta nudges your heartrate up slightly. Not a problem. If it ever turns noticeable or uncomfortable, that's probably an electrolyte imbalance — you need more sodium, potassium, or magnesium. Follow Daddy's instructions above and magnesium is covered.

Start doing cardio. It brings blood pressure down and keeps things moving as you get healthier.

At goal weight, that's when you can add testosterone and pleasure your wife 4 to 6 times a day.

Good luck on your journey!

P.S.

One more thing...

In my opinion, injecting reta weekly is idiotic. Reta's appetite suppression fades after 4-5 days. I inject every 3 days and I pity anyone going more than 5 days between injections. Anyone calling this bad information is wrong and should feel bad.

Starting weight, 236, current weight 207. 10 weeks. That's 3lbs a week, which is a little unhealthy. Began at 0.5mg, raised by 0.5mg every 2 days until reaching 2.33mg per week (1mg every 3 days). Bumped to 4.66mg/wk at week 5 (2mg every 3 days) and see no reason to increase dose further at this time. 27y/o male

It's not that I doubt you — this is simply how I do things. One injection weekly for us. As I see it, the hunger blunting stays steady. Over 19 weeks: 46lbs, which works out to 2.4lb each week on average.

BNLFL, that wasn't aimed at you! I was referring to folks who don't have your level of coolness. You're among the good ones!

Mind passing that message along to my wife, brother?

Honestly, the only situations where I'd say 1mg makes sense are if someone is extremely sensitive, or if their diet and appetite are already dialed in.

In my own family, I saw 2 people begin at 1mg and then move to 2mg 4 weeks later. To me that looks like a clever method for burning time and ruining how well the drug will work down the road.

My mom was 1 of them. She ended up needing 6mg per week instead of 4mg, since 5mg wasn't sufficient for her. My take is that 1mg makes you tolerant to the drug quite fast. Acclimating takes only 1-2 weeks, and most side effects clear up within 3-4 weeks.

From some study material I went through, beginning at a lower dose seems to aid adaptation — or plasticity, to use their term — and greatly lessens side effects while a person titrates upward. When the starting dose was higher, the findings indicated the body never adjusted, and those in that group continued to have noticeably more side effects.

That's just some anonymous individual's claim, not research. Going in too high or ramping up too fast is clearly a bad idea, but the goal should be to begin at or close to a dose that actually works. Begin too low and your responsiveness to the medication fades, meaning you'll need more of it to get results other people reach on a smaller amount.

Or maybe at 28 you don't have all the answers, and it was a study...

 

[birdwhacker]

GLPFrodo said:

birdwhacker said:

GLPFrodo said:

birdwhacker said:

BNLFL said:

kmngq said:

Took my 2nd injection on Sunday. 1mg.

Honestly, I have no idea whether it's doing anything. I suppose not having any side effects is a positive thing.

That dose is on the low side. Either follow what @birdwhacker suggested, or keep it there for a full 4 weeks so it accumulates in your body, then raise it to 2mg.

birdwhacker said:

BNLFL said:

birdwhacker said:

Powerslide said:

Took my 3rd dose (1mg) on Saturday night (day 6) right before going to sleep, and it seemed to reduce the mild side effects I'd been having. That first night I slept well, but the following night I couldn't fall asleep and woke up a few hours later. It definitely appears to be accumulating in my system — even at 1mg I can't consume nearly as much as before. I'm thinking about junk food, soda, and similar stuff less and less, and for the most part I'm making better choices at the grocery store. This morning the scale showed 229. The khaki pants and black shorts I wear to work, which used to be stretched tight, no longer feel like they're cutting off my circulation, and trimming my toenails is a bit less uncomfortable.

Weeks 1 through 3 are the toughest stretch. Don't skip your supplements: a methylated B complex, trace minerals, magnesium taken at night, plus electrolytes — those are the floor, not the ceiling.

Since I'm clearly wired a little differently, here come the product links. In my view these are extremely helpful, maybe even mandatory, so that whatever side effects show up can be blamed on bad nutrition instead of the reta.

• https://a.co/d/09wqgsjj 1 pill after your evening meal; work up to 2 as your stool softness permits. Add fiber wherever you can — psillium husk (metamucil) works wonders.
  
• https://a.co/d/07E78CCj Honestly, buying most of these separately would be better. Still, not everyone is as into vitamins as I am, so here's a middle ground. Take it with food or without, however you tolerate it.
  
• https://a.co/d/08mqDPmk 2 every morning before eating.

That list is the floor. If side effects hit you and you haven't covered these basics, I've got no sympathy. NOW Foods liquid fish oil plus whatever psilium husk brand you like are also hugely helpful.

Now, back to those first 3 weeks...

Sleep problems will get worse before they get better. Eventually they settle down. Avoid carbs in the evening. Anything you eat past 5pm deserves caution, because it rides with you into sleep. Carbs make sleep worse. A little low fat cheese or casein protein powder before bed keeps you asleep and delivers solid lowfat, lowcarb protein. Casein breaks down slowly, so your body won't jolt you awake from insulin crashing (carbs gone) or cortisol (body acting like it's starving) surging overnight.

Your skin may get sensitive. If it's severe, an antihistamine can help, though it shouldn't reach that point. I also found my sense of smell permanently sharpened a touch.

During the first few weeks you might feel wiped out, stay in bed, and even like it — because for the first time in years you've stopped overeating. Don't settle in there. Time to show up and get 3+ balanced meals daily with enough protein. Time to learn TDEE, BMI, and cardio zones. Don't burn this chance.

Reta nudges your heartrate up slightly. Not a problem. If it ever turns noticeable or uncomfortable, that's probably an electrolyte imbalance — you need more sodium, potassium, or magnesium. Follow Daddy's instructions above and magnesium is covered.

Start doing cardio. It brings blood pressure down and keeps things moving as you get healthier.

At goal weight, that's when you can add testosterone and pleasure your wife 4 to 6 times a day.

Good luck on your journey!

P.S.

One more thing...

In my opinion, injecting reta weekly is idiotic. Reta's appetite suppression fades after 4-5 days. I inject every 3 days and I pity anyone going more than 5 days between injections. Anyone calling this bad information is wrong and should feel bad.

Starting weight, 236, current weight 207. 10 weeks. That's 3lbs a week, which is a little unhealthy. Began at 0.5mg, raised by 0.5mg every 2 days until reaching 2.33mg per week (1mg every 3 days). Bumped to 4.66mg/wk at week 5 (2mg every 3 days) and see no reason to increase dose further at this time. 27y/o male

It's not that I doubt you — this is simply how I do things. One injection weekly for us. As I see it, the hunger blunting stays steady. Over 19 weeks: 46lbs, which works out to 2.4lb each week on average.

BNLFL, that wasn't aimed at you! I was referring to folks who don't have your level of coolness. You're among the good ones!

Mind passing that message along to my wife, brother?

Honestly, the only situations where I'd say 1mg makes sense are if someone is extremely sensitive, or if their diet and appetite are already dialed in.

In my own family, I saw 2 people begin at 1mg and then move to 2mg 4 weeks later. To me that looks like a clever method for burning time and ruining how well the drug will work down the road.

My mom was 1 of them. She ended up needing 6mg per week instead of 4mg, since 5mg wasn't sufficient for her. My take is that 1mg makes you tolerant to the drug quite fast. Acclimating takes only 1-2 weeks, and most side effects clear up within 3-4 weeks.

From some study material I went through, beginning at a lower dose seems to aid adaptation — or plasticity, to use their term — and greatly lessens side effects while a person titrates upward. When the starting dose was higher, the findings indicated the body never adjusted, and those in that group continued to have noticeably more side effects.

That's just some anonymous individual's claim, not research. Going in too high or ramping up too fast is clearly a bad idea, but the goal should be to begin at or close to a dose that actually works. Begin too low and your responsiveness to the medication fades, meaning you'll need more of it to get results other people reach on a smaller amount.

Or maybe at 28 you don't have all the answers, and it was a study...

Do you have a source for what you copied and pasted? It reads like AI.

Those studies began at 2mg and 4mg.