Labcat said:
I'd been running ghkCu/basic at 50:20, plus kpv, which I injected first into the same spot, and I added a bit of topical hydrocortisone for extra measure… I was titrating toward 4.5mg/day split into separate doses… and that was genuinely helping shut down my migraines… there was zero sting right away, but 2-5 hours afterward I'd feel stinging in that same leg at
other spots I'd previously injected and where I'd had bruises. My read on that was that some kind of healing process was underway.
Roughly 1 week in, delayed itching began, along with a bump deep under the skin at the injection site that itched but wasn't hives. I moved to abdominal sq sites and every bump became substantially smaller. A few days later, though, the sites on my other leg where I do qd lira and ss31 also started producing delayed itchy bumps. Meanwhile my scalp had grown itchier, and so had my skin generally. I've tended to be fairly environmentally allergic in the past, and with the recent rains we're getting an early spring allergy season here, so that was piling on top.
It's still confined to 1 organ system (skin), so it isn't anaphylaxis. Even so, it looked like a mast cell reaction, a mechanical irritation, except it was also spilling over into making me more reactive to real allergies, which can happen. I began to suspect my needles and pen needles, which are honestly pretty poor quality, maybe the rubber stoppers, or some component common to all the products (my rather $$$$ Rx'd generic lira pen actually shipped from CN, so I strongly suspect it too is recon'd lyo'd pep).
I spoke with someone who'd had similar reactions and who took 5 days of high dose brand name Zyrtec antihistamine (4 pills a day, but do check with your doctor to make sure you're not missing or covering up increased anaphylaxis risk, which can be the case with those with atopic dermatitis or mast cell disorders, and mast cell disorders are apparently underdiagnosed since 50% of people with history of wasp sting anaphylaxis im one study turned out to have a mast cell clonal disorder ).
So, with my neffies within reach, I'm on day 3 of antihistamines and down to only 1.5mg of ghk, and I can report it has relieved my insomnia
and I'm less itchy, though new itchy welts keep appearing. I went back to topical hydrocortisone, which helps.
My next idea is to try ghk basic by itself, following the copper theory, but I'm somewhat concerned I may have to pause every injection so my mast cells can calm down, if literally everything sets this off.
Is anyone else reacting to ghk while also taking tirz? Tirz is probably quite effective at damping mast cell inflammation. If you take tirz and ghkcu, could you tell us whether you get any kind of isrs?
Anyone whose reaction is spreading should be very careful, and probably more careful than I've been. Antihistamines
DO NOT treat or prevent anaphylaxis. Anyone who has had anaphylaxis before is likely at higher risk for another episode. Epi does not save everyone who gets anaphylaxis!
