Doing stupid things in the name of science...

Shittersfull said:

Foggy-Hollow said:

Shittersfull said:

I pull dumb stunts constantly. Microwaving a canister of butane? Been there. No judgment from me, but jumping straight into that kind of reta dose is something I'd steer clear of. Best of luck to you. Might be smart to have something on hand for constipation. Stay hydrated. Keep us posted.
😮😳 to what extent was it filled or not?

Did the fire department get heated over that?
The thing was packed to the brim. The plastic valve sitting on top melted down, which let butane flood the microwave before it caught fire fast and burned itself out just as fast. I pulled this stunt right in the center of my driveway.

Honestly, I can't decide if that's impressive or just plain terrifying. 😆
 
Foggy-Hollow said:

Shittersfull said:

Foggy-Hollow said:

Shittersfull said:

I pull dumb stunts constantly. Microwaving a canister of butane? Been there. No judgment from me, but jumping straight into that kind of reta dose is something I'd steer clear of. Best of luck to you. Might be smart to have something on hand for constipation. Stay hydrated. Keep us posted.
😮😳 to what extent was it filled or not?

Did the fire department get heated over that?
The thing was packed to the brim. The plastic valve sitting on top melted down, which let butane flood the microwave before it caught fire fast and burned itself out just as fast. I pulled this stunt right in the center of my driveway.

Honestly, I can't decide if that's impressive or just plain terrifying. 😆
A classic "hold my beer, watch this" situation for me. Still not as wild as pinning 4mg of reta on your very first shot.
 
Shittersfull said:

Foggy-Hollow said:

Shittersfull said:

Foggy-Hollow said:

Shittersfull said:

I pull dumb stunts constantly. Microwaving a canister of butane? Been there. No judgment from me, but jumping straight into that kind of reta dose is something I'd steer clear of. Best of luck to you. Might be smart to have something on hand for constipation. Stay hydrated. Keep us posted.
😮😳 to what extent was it filled or not?

Did the fire department get heated over that?
The thing was packed to the brim. The plastic valve sitting on top melted down, which let butane flood the microwave before it caught fire fast and burned itself out just as fast. I pulled this stunt right in the center of my driveway.

Honestly, I can't decide if that's impressive or just plain terrifying. 😆
A classic "hold my beer, watch this" situation for me. Still not as wild as pinning 4mg of reta on your very first shot.
An M80 got taped by us onto a coke can that was full of gasoline...

After it detonated, the can fell over and the fuel spilled out with no ignition.. we gave it a shot..
 
Shittersfull said:

Foggy-Hollow said:

Shittersfull said:

Foggy-Hollow said:

Shittersfull said:

I pull dumb stunts constantly. Microwaving a canister of butane? Been there. No judgment from me, but jumping straight into that kind of reta dose is something I'd steer clear of. Best of luck to you. Might be smart to have something on hand for constipation. Stay hydrated. Keep us posted.
😮😳 to what extent was it filled or not?

Did the fire department get heated over that?
The thing was packed to the brim. The plastic valve sitting on top melted down, which let butane flood the microwave before it caught fire fast and burned itself out just as fast. I pulled this stunt right in the center of my driveway.

Honestly, I can't decide if that's impressive or just plain terrifying. 😆
A classic "hold my beer, watch this" situation for me. Still not as wild as pinning 4mg of reta on your very first shot.
Fuuuuuuuck! 🤣
 
razelito said:

Kicking off with 4mg of reta is wild... Good thing you managed to figure out some kind of equilibrium
Not exactly—the clinical trials assigned separate cohorts to begin at varying doses. This was done to evaluate adverse effects.
 
CNCCurrency said:

razelito said:

Kicking off with 4mg of reta is wild... Good thing you managed to figure out some kind of equilibrium
Not exactly—the clinical trials assigned separate cohorts to begin at varying doses. This was done to evaluate adverse effects.
Coraline is so pretty, OMFG!

I switched back to 5mg tirz / 1mg reta and will titrate reta up slowly. The numbers aren't definitive, I realize, but I "feel" like a sweetspot might be waiting for me on the way to 5mg/4mg...
 
razelito said:

Kicking off with 4mg of reta is wild... Good thing you managed to figure out some kind of equilibrium
My own reta ramp was extremely careful: it took many weeks to move from .5 up to 2mg. After that, I leapt straight to 4mg. Why, I honestly can't say — maybe because I'd had zero troublesome sides. Or maybe just cowboy impatience.

4mg wrecked me! Anecdotally, I've seen a strange split — certain people got nothing at all below 4mg and then sailed along smoothly, while others spent several days feeling like death.

These days I'm not on it. I did a single 2.5mg shot and that was that. Going higher than that isn't something I plan to try. Burned once, shy forever.
 
Not quite as severe as the individual who accidentally pinned r 20 right from the start. They're dead now. So. Yeah, don't do that.
 
razelito said:

Kicking off with 4mg of reta is wild... Good thing you managed to figure out some kind of equilibrium
In 2024, when I first got going, 4mg was a fairly normal place for people to begin. Options were basically 2 or 4. The phase 2 trials had used those doses, and folks picked their starting point from that trial data.

After that, TikTok influencers began putting out videos.
 
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