Berberine helped break plateau

J

jmikes

New member
Joined
Aug 19, 2026
Messages
6
Reaction score
0
Location
Imported archive
I have been on compound tirzepatide for nine months. I was stuck at five pounds from my goal weight. I have lost 70 pounds and am only on 5mg. I didn't want to titrate up for the last few pounds. I tried 2000mg/day of berberine, and poof, I am just below goal weight in a week.
 
deluge said:


Huh, never heard of Berberine before. I've got a bit of reading to do!

Click to expand...
Click to expand...
It’s the active compound in turmeric, and is often mixed with black pepper and cinnamon. It’s been touted as nature’s ozempic (idk about that, studies are “promising but inconclusive,” but I like it nonetheless). I used it a lot the last time I lost weight, which was also my most successful pre-GLP drop (I was also diet/exercising). It has nice anti-inflammatory properties!
 
HouseCat said:


It’s the active compound in turmeric, and is often mixed with black pepper and cinnamon. It’s been touted as nature’s ozempic (idk about that, studies are “promising but inconclusive,” but I like it nonetheless). I used it a lot the last time I lost weight, which was also my most successful pre-GLP drop (I was also diet/exercising). It has nice anti-inflammatory properties!

Click to expand...
Click to expand...
Berberine? “Nature’s Ozempic” is Olympic gymnastics level of stretching. Nature’s metformin maybe.
 
quicksilver80 said:


Dont they expressly tell you not to take that with glp1s?

Click to expand...
Click to expand...
Take what? Neither berberine or metformin are contraindicated with GLP-1s (plenty of diabetics take metformin and a GLP-1), though “too much good stuff” can potentially be an issue when people stack multiple glucose-lowering drugs and supplements.
 
SVT810E said:


Take what? Neither berberine or metformin are contraindicated with GLP-1s (plenty of diabetics take metformin and a GLP-1), though “too much good stuff” can potentially be an issue when people stack multiple glucose-lowering drugs and supplements.

Click to expand...
Click to expand...
Yeah read its on the same air as using stims or clen on reta because of the heart/rate risk.

berberine and glp1 can send you into dangerously low blood sugar levels aka hypoglycemia.
 
quicksilver80 said:


Yeah read its on the same air as using stims or clen on reta because of the heart/rate risk.

berberine and glp1 can send you into dangerously low blood sugar levels aka hypoglycemia.

Click to expand...
Click to expand...
Reta can cause hypoglycemia on its own. It doesn’t need any help to pull that off.

It’s like a lot of other things… the dose makes the poison but also the victim makes the poison. A diabetic might need reta and metformin and empagliflozin to successfully manage their blood sugar. I’m pretty sure that combo would kill me. Lots of people all over the place in between.
 
Back
Top